METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES

申请号 US15108259 申请日 2014-12-23 公开(公告)号 US20160326553A1 公开(公告)日 2016-11-10
申请人 GENOMATICA, INC.; 发明人 Anthony P. BURGARD; Robin E. OSTERHOUT; Stephen J. VAN DIEN; Priti PHARKYA; Tae Hoon YANG; Jungik CHOI;
摘要 The invention is directed to a non-naturally occurring microbial organism comprising a first attenuation of a succinyl-CoA synthetase or transferase and at least a second attenuation of a succinyl-CoA converting enzyme or a gene encoding a succinate producing enzyme within a multi-step pathway having a net conversion of succinyl-CoA to succinate.
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