Listeria-Based Immunogenic Compositions And Methods Of Use Thereof in Cancer Prevention And Treatment

申请号 US15563447 申请日 2016-09-14 公开(公告)号 US20180305702A1 公开(公告)日 2018-10-25
申请人 Advaxis, Inc.; 发明人 Robert Petit; Michael F. Princiotta; Kyle Perry;
摘要 Disclosed herein are recombinant Listeria strains comprising nucleotides encoding two or more heterologous antigens each fused to a truncated LLO, an N-terminal ActA or a PEST-sequence, methods of preparing same, and methods of inducing an immune response, and treating, inhibiting, or suppressing cancer or tumors comprising administering same.
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