Listeria-Based Immunogenic Compositions And Methods Of Use Thereof in Cancer Prevention And Treatment |
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申请号 | US15563447 | 申请日 | 2016-09-14 | 公开(公告)号 | US20180305702A1 | 公开(公告)日 | 2018-10-25 |
申请人 | Advaxis, Inc.; | 发明人 | Robert Petit; Michael F. Princiotta; Kyle Perry; | ||||
摘要 | Disclosed herein are recombinant Listeria strains comprising nucleotides encoding two or more heterologous antigens each fused to a truncated LLO, an N-terminal ActA or a PEST-sequence, methods of preparing same, and methods of inducing an immune response, and treating, inhibiting, or suppressing cancer or tumors comprising administering same. | ||||||
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说明书全文 |