RECOMBINANT FUSION PROTEINS FOR PREVENTING OR TREATING ADHESIONS OF TISSUES OR ORGANS

申请号 US15506558 申请日 2015-08-20 公开(公告)号 US20170253864A1 公开(公告)日 2017-09-07
申请人 Akesion GmbH; 发明人 Klaus Rübsamen; Stephan Witte;
摘要 The invention relates to recombinant fusion proteins comprising a fibrinogenolytic enzyme having an amino acid sequence that is C-terminally and/or N-terminally linked to the amino acid sequence of at least one high-molecular inert stabilization domain with a molecular weight of >50 kDa, for the prevention or treatment of adhesions at tissues or organs, in particular peritoneal adhesions following surgical interventions.
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