Detecting neoplasm from a stool sample |
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申请号 | EP11189541.3 | 申请日 | 2009-02-11 | 公开(公告)号 | EP2474626A3 | 公开(公告)日 | 2012-08-01 |
申请人 | Mayo Foundation For Medical Education And Research; | 发明人 | Taylor, William R.; Harrington, Jonathan J.; Quint, Patrick S.; Hongzhi, Zou; Bergen, Harold R., III; Smith, David I.; | ||||
摘要 | The present invention relates to a method of detecting cancer in a mammal, said method comprising determining whether or not a stool sample from said mammal comprises an elevated K-ras mutation score, an elevated BMP3 methylation status, and an elevated level of human DNA as compared to a normal control, wherein the presence of said elevated K-ras mutation score, said elevated BMP3 methylation status, and said elevated level of human DNA level indicates that said mammal has cancer. | ||||||
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