RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF |
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| 申请号 | US15880029 | 申请日 | 2018-01-25 | 公开(公告)号 | US20180155703A1 | 公开(公告)日 | 2018-06-07 |
| 申请人 | Proteon Therapeutics, Inc.; | 发明人 | F. Nicholas FRANANO; Kimberly Bland; Marco D. Wong; Bee C. Ding; | ||||
| 摘要 | The present invention relates to methods for the manufacture, purification, formulation, and use of biologically active recombinant elastase proteins. Described are recombinant methods for producing therapeutically useful elastase proteins, as are pharmaceutical compositions comprising said elastase proteins. Novel recombinant elastase proteins and protein preparations are also disclosed. Methods are described for treating and preventing diseases of biological conduits using pharmaceutical compositions containing the elastase proteins of the invention. | ||||||
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| 说明书全文 | |||||||
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