DRUG REGIMEN FOR TREATMENT OF CEREBRAL ISCHEMIA

申请号 US15859075 申请日 2017-12-29 公开(公告)号 US20180185475A1 公开(公告)日 2018-07-05
申请人 Shimojani, LLC; 发明人 Lawrence M. KAUVAR; Damir JANIGRO;
摘要 Treatment of subjects experiencing cerebral ischemia is improved when the treatment employs a thrombolytic and an inhibitor against vascular endothelial growth factor receptor signal transduction (VEGF-RST) at a reduced, low dosage compared to that used to treat cancer patients. The treatment is also improved to permit point-of-care use by formulating protein drugs for long term stability at room temperature, providing doses appropriate for the method, and by combining the therapeutic agents with a point-of-care diagnostic for blood brain barrier integrity.
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