| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 41 | 감각 유모 세포 사멸을 예방 또는 치료하기 위한 화합물 및 방법 | KR20177025003 | 2016-02-05 | KR20180003530A | 2018-01-09 | |
| 본원은청력손실을예방하거나치료하기위한화합물, 및이러한화합물을포함하는약학조성물을개시한다. 본원에기재된화합물및 약학조성물은유모세포사멸을예방하거나치료한다. 또한, 본원에기재된화합물및 약학조성물은아미노글리코사이드항생제를투여받는개체에서신장손상으로부터보호한다. 본발명은또한, 단독으로또는다른치료제와조합한본 화합물의사용방법을개시한다. | ||||||
| 42 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | PCT/US2016016880 | 2016-02-05 | WO2016127123A2 | 2016-08-11 | SIMON JULIAN; JOHNSON GRAHAM; RUBEL EDWIN W; RAIBLE DAVID W; GONZALEZ MARIO D; MELTZER PETER C; MIAO WEISHI |
Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing or treating hearing loss. The compounds and pharmaceutical compositions described herein prevent or treat hair cell death. In addition, the compounds and pharmaceutical compositions described herein protect against kidney damage in an individual receiving an aminoglycoside antibiotic. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed. |
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| 43 | METHYL 2,4,9-TRITHIAADAMANTANE-7-CARBOXYLATE | PCT/US2004021558 | 2004-07-01 | WO2005120186A3 | 2007-08-16 | JUN HU |
| Methyl 2,4,9-trithiaadamantane-7-carboxylate and a method for its manufacture is disclosed. The method reacts oxidized methyl triallyl acetate with a Lewis acid and a sulphuring agent. | ||||||
| 44 | ANTICANCER AND ANTIPROTOZOAL DIHYDROARTEMISINENE AND DIHYDROARTEMISITENE DIMERS WITH DESIRABLE CHEMICAL FUNCTIONALITIES | PCT/US2005021826 | 2005-06-21 | WO2006002105A8 | 2007-03-01 | ELSOHLY MAHMOUD A; GUL WASEEM |
| This invention comprises compositions containing dihydroartemisinin- and dihydroartemisitene- dimers with activity as anticancer or anticancer metastasis agents and anti-protozal, including anti-malarial and anti-leishmanial properties. This invention also describes methods of preparation of these compositions and methods of use of such compositions for the treatment of cancer or prevention of cancer metastasis, and protozoal infections, including malaria, or leishmaniasis. The compounds of this invention represent a potential new class of anti-tumor or anti-metastasis agents, one that has shown promising activity against solid tumors. | ||||||
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