| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 181 | MAGNESIUM PHOSPHATE BIOMATERIALS | US14342027 | 2012-08-31 | US20140305344A1 | 2014-10-16 | Jake Edward Barralet; Faleh Ahmad Tamimi Marino; Andrew Paul Flynn |
| There is provide a solid cement reactant comprising a dehydrated magnesium phosphate, and/or an amorphous or partially amorphous magnesium phosphate, and/or Farringtonite. | ||||||
| 182 | Hydraulic Cements, Methods and Products | US14246679 | 2014-04-07 | US20140221303A1 | 2014-08-07 | Håkan Engqvist; Jonas Åberg |
| Non-aqueous hydraulic cement compositions comprise a non-aqueous mixture of a powder composition and a non-aqueous water-miscible liquid. In one embodiment, powder composition is a Brushite or Monetite-forming calcium phosphate powder composition. In another embodiment, the powder composition comprises porous β-tricalcium phosphate (β-TCP) granules and at least one additional calcium phosphate powder. In another embodiment, the powder composition comprises calcium silicate powder. In a further embodiment, the powder composition comprises calcium aluminate powder. In another embodiment, the powder composition is a cement composition and comprises nanopowders having a grain size of less than 1 micron. Hardened cements are formed from such hydraulic cement compositions, and methods of producing hardened cements, kits, and articles of manufacture employ such hydraulic cement compositions. | ||||||
| 183 | Hydraulic cements, methods and products | US13128034 | 2009-11-12 | US08709149B2 | 2014-04-29 | H{dot over (a)}kan Engqvist; Jonas Aberg |
| Non-aqueous hydraulic cement compositions comprise a non-aqueous mixture of a powder composition and a non-aqueous water-miscible liquid. In one embodiment, powder composition is a Brushite or Monetite-forming calcium phosphate powder composition. In another embodiment, the powder composition comprises porous β-tricalcium phosphate (β-TCP) granules and at least one additional calcium phosphate powder. In another embodiment, the powder composition comprises calcium silicate powder. In a further embodiment, the powder composition comprises calcium aluminate powder. In another embodiment, the powder composition is a cement composition and comprises nanopowders having a grain size of less than 1 micron. Hardened cements are formed from such hydraulic cement compositions, and methods of producing hardened cements, kits, and articles of manufacture employ such hydraulic cement compositions. | ||||||
| 184 | HYDRAULIC CEMENT COMPOSITIONS WITH LOW PH METHODS, ARTICLES AND KITS | US13229534 | 2011-09-09 | US20130066327A1 | 2013-03-14 | Håkan Engqvist; Jonas Áberg |
| A non-aqueous hydraulic cement composition comprises a non-aqueous mixture of (a) β-tricalcium phosphate powder, (b) monocalcium phosphate comprising monocalcium phosphate anhydrous (MCPA), monocalcium phosphate monohydrate (MCPM), or a combination thereof, and (c) non-aqueous water-miscible liquid, wherein a 0.1 g/ml saturated aqueous solution of the monocalcium phosphate has a pH less than 3.0. Methods of producing a hardened cement, hardened cements, kits, and articles of manufacture employ such compositions. | ||||||
| 185 | Tricalcium Phosphate Coarse Particle Compositions and Methods for Making the Same | US13554999 | 2012-07-20 | US20130017233A1 | 2013-01-17 | Sahil Jalota; David C. Delaney; Duran N. Yetkinler |
| Methods for preparing a tricalcium phosphate coarse particle composition are provided. Aspects of the methods include converting an initial tricalcium phosphate particulate composition to hydroxyapatite, sintering the resultant hydroxyapatite to produce a second tricalcium phosphate composition and then mechanically manipulating the second tricalcium phosphate composition to produce a tricalcium phosphate coarse particle composition. The subject methods and compositions produced thereby find use in a variety of applications. | ||||||
| 186 | Calcium phosphate particles and hydraulic cements based thereon | US12990744 | 2008-05-02 | US08287641B2 | 2012-10-16 | Marc Bohner |
| Calcium phosphate particles having A) a specific surface area (SSA) larger than 0.1 m2/g; B) a mean diameter smaller than 5 mm; C) a Ca/P molar ratio superior to 0.95; and wherein D) said particles have been subjected as a last processing step to a heat treatment at a temperature superior to 400° C. for a period of time such that the specific surface area (SSA) of said particles after the heat treatment is not decreased by more than 10% compared to the SSA before said heat treatment. | ||||||
| 187 | Tricalcium Phosphate Coarse Particle Compositions and Methods for Making the Same | US13153308 | 2011-06-03 | US20120000394A1 | 2012-01-05 | Sahil Jalota; David C. Delaney; Duran N. Yetkinler |
| Methods for preparing a tricalcium phosphate coarse particle composition are provided. Aspects of the methods include converting an initial tricalcium phosphate particulate composition to hydroxyapatite, sintering the resultant hydroxyapatite to produce a second tricalcium phosphate composition and then mechanically manipulating the second tricalcium phosphate composition to produce a tricalcium phosphate coarse particle composition. The subject methods and compositions produced thereby find use in a variety of applications. | ||||||
| 188 | Novel Phosphorus-calcium-strontium compound and uses thereof in endodontic cements | US12373225 | 2007-07-09 | US20100068677A1 | 2010-03-18 | Philippe BOUDEVILLE |
| Phosphorus-calcium-strontium compound of formula (I); method for preparing same; composition for the extemporaneous preparation of a cement comprising a solid phase (SP) and a liquid phase (LP), wherein the solid phase comprises a mixture of inorganic compounds of formula (II); use as an endodontic cement. | ||||||
| 189 | Hydraulic cement based on calcium phosphate for surgical use | US10598500 | 2004-03-08 | US07670419B2 | 2010-03-02 | Marc Bohner |
| A hydraulic cement based on calcium phosphate for surgical use comprising A) a first component comprising powder particles of calcium phosphate; and B) a second component comprising water. The calcium phosphate comprises anhydrous, amorphous calcium phosphate (ACP) and the ACP is obtained by milling a calcium phosphate synthesized above 500° C. The cement according to the invention has the advantage of being very fast setting compared to prior art calcium phosphate cements. The setting reaction is finished much faster although the initial part of the reaction proceeds at the same speed as with known cements. | ||||||
| 190 | High strength biological cement composition and using the same | US11584132 | 2006-10-20 | US07553362B2 | 2009-06-30 | Donghui Lu; Shuxin Zhou |
| A hydraulic cement for biomedical applications. The cement sets in-situ, hardening when exposed to water to produce nano-dispersed composite of calcium-silicate-hydrate gel mixed with hydroxyapatite. In comparison with prior cements, the composition provides high biocompatibility, high bioactivity and high biomechanical strength, due to the composite structure of the calcium silicate hydrate reinforced with co-precipitated particles of hydroxyapatite. Biocompatibility is also increased due to an absence of aluminum and magnesium in the composition. The cement is suitable for variety of applications, including dental implants, bone fixation, and bone repair. | ||||||
| 191 | COAL COMBUSTION PRODUCT CEMENTS AND RELATED METHODS OF PRODUCTION | US11758608 | 2007-06-05 | US20080264301A1 | 2008-10-30 | Marc Porat; Iqbal Gill; Sarah Billington |
| Coal combustion product cement compositions produced using classes of relatively low-cost industrial by-products and low-value minerals. A variety of highly sustainable cements with low-environmental impact can be provided. Coal combustion by-products and other wastes produced on the large scale from the burning of coal or coal and biomass in coal-fired power stations with or without low-value minerals, processed minerals, and/or by-products of the mining, mineral processing, metal refining, petrochemical, fine chemical, pharmaceutical, agrochemical, biotechnology, food, feed and energy industries, as well as agricultural and municipal by-products, can be utilized to provide improved cements and cementitious materials that are more economic and environmentally friendly than traditional cements including Portland cement. | ||||||
| 192 | Method of increasing working time of tetracalcium phosphate cement paste | US10940922 | 2004-09-14 | US07270705B2 | 2007-09-18 | Jiin-Huey Chern Lin; Chien-Ping Ju; Wen-Cheng Chen; Kuan-Liang Lin; I-Chang Wang |
| A method for increasing working time/setting time of monolithic tetracalcium phosphate (TTCP) cement paste formed by mixing a TTCP powder with an aqueous solution, which includes heating the TTCP powder, prior to the mixing, so that the TTCP powder is maintained at a temperature of 50-350° C. for a period of time which is greater than one minute, and that a TTCP cement paste formed by mixing the resulting heated TTCP powder with the aqueous solution has a prolonged working time in comparison with that formed by mixing TTCP powder that has not been subjected to such heating with the aqueous solution. | ||||||
| 193 | Injectable calcium phosphate cements and the preparation and use thereof | US11129227 | 2005-05-13 | US07258734B2 | 2007-08-21 | Jiin-Huey Chern Lin; Chien-Ping Ju; Wen-Cheng Chen |
| A calcium phosphate cement suitable for use in dental and bone prosthesis is disclosed, which include calcium phosphate particles having a diameter of 0.05 to 100 microns, wherein said calcium phosphate particles on their surfaces have whiskers or fine crystals having a width ranging from 1 to 100 nm and a length ranging from 1 to 1000 nm. | ||||||
| 194 | Hydraulic cement based on calcium phosphate for surgical use | US10598500 | 2004-03-08 | US20070186818A1 | 2007-08-16 | Marc Bohner |
| A hydraulic cement based on calcium phosphate for surgical use comprising A) a first component comprising powder particles of calcium phosphate; and B) a second component comprising water. The calcium phosphate comprises anhydrous, amorphous calcium phosphate (ACP) and the ACP is obtained by milling a calcium phosphate synthesized above 500° C. The cement according to the invention has the advantage of being very fast setting compared to prior art calcium phosphate cements. The setting reaction is finished much faster although the initial part of the reaction proceeds at the same speed as with known cements. | ||||||
| 195 | Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same | US11133165 | 2005-05-19 | US07204876B2 | 2007-04-17 | Jiin-Huey Chern Lin; Chien-Ping Ju; Wen-Cheng Chen |
| A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers on a surface thereof; the basic calcium phosphate whiskers having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm. The basic calcium phosphate whiskers are substantially free of a hydroxyapatite phase and mainly composed of TTCP phase. | ||||||
| 196 | Process for affecting the setting and working time of, bioresorbable calcium phosphate cements | US11137695 | 2005-05-25 | US07201797B2 | 2007-04-10 | Jiin-Huey Chern Lin; Chien-Ping Ju; Kuan-Liang Lin; I-Chang Wang |
| A fast-setting, bioresorbable calcium phosphate cement is prepared by a process which can be carried out with a heat treatment up to 1000° C. on a mixture of a wetting solution and a calcium phosphate powder having a Ca to P molar ratio of 0.5–2.5. The wetting solution suitable for use in the process of the present invention includes water, an organic solvent, an acidic and basic solution. A setting solution for mixing with the heated powder to form the fast-setting, bioresorbable calcium phosphate cement may be water, an acidic or basic solution according to the process of the present invention. | ||||||
| 197 | Process for affecting the setting and working time of bioresorbable calcium phosphate cements | US11137112 | 2005-05-25 | US07186294B2 | 2007-03-06 | Jiin-Huey Chern Lin; Chien-Ping Ju; Wen-Cheng Chen |
| A fast-setting, bioresorbable calcium phosphate cement is prepared by a process which can be carried out with a heat treatment up to 1000° C. on a mixture of a wetting solution and a calcium phosphate powder having a Ca to P molar ratio of 0.5–2.5. The wetting solution suitable for use in the process of the present invention includes water, an organic solvent, an acidic and basic solution. A setting solution for mixing with the heated powder to form the fast-setting, bioresorbable calcium phosphate cement may be water, an acidic or basic solution according to the process of the present invention. | ||||||
| 198 | Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same | US11133152 | 2005-05-19 | US07182928B2 | 2007-02-27 | Jiin-Huey Chern Lin; Chien-Ping Ju; Wen-Cheng Chen |
| A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers on a surface thereof; the basic calcium phosphate whiskers having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm. The basic calcium phosphate whiskers are substantially free of a hydroxyapatite phase and mainly composed of TTCP phase. | ||||||
| 199 | Tetracalcium phosphate (TTCP) with surface whiskers and method of making same | US11131892 | 2005-05-18 | US07160381B2 | 2007-01-09 | Jiin-Huey Chern Lin; Chien-Ping Ju; Wen-Cheng Chen |
| A tetracalcium phosphate (TTC P) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers or fine crystals on a surface thereof; the basic calcium phosphate whiskers or fine crystals having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm. | ||||||
| 200 | Tetracalcium phosphate (TTCP) with surface whiskers and method of making same | US11132167 | 2005-05-18 | US07156915B2 | 2007-01-02 | Jiin-Huey Chern Lin; Chien-Ping Ju; Wen-Cheng Chen |
| A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers or fine crystals on a surface thereof; the basic calcium phosphate whiskers of fine crystals having a Ca/P molar greater that 1.33, and having a length up to about 5000 nm and a width up to about 500 nm. | ||||||
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