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序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
141 Solid - liquid separation method JP2006526891 2004-08-04 JP2007505735A 2007-03-15 ウィルサック,リチャード・エイ; コムストック,ディーン・ビー; ステファンスキ,ロナルド; ハフ,ジョージ・エイ; ロバーツ,スコット・エイ
フィルターによって分離されている高濃度ゾーン及び低濃度ゾーンによって画定された濾過ゾーン内で液体から固体を分離する方法。 本方法は、液体及び固体を含むスラリー供給物を高濃度ゾーンに送る工程、置換流体を高濃度ゾーンに送る工程、液体の少なくとも一部をフィルターを通して濾液ゾーンに送り、濾液を生じさせる工程を含む。
142 Imaging of automated protein crystallisation JP2003584270 2003-04-10 JP2005520174A 2005-07-07 リリング デイブ; グリーンウエイ ブライアン
多くの結晶化プレートに含まれる結晶化実験の画像を自動的に取得、分析及び蓄積する装置である。 本装置は、複数の種類の蛋白質結晶化プレートを収容可能なプレートネストと、対物レンズと結晶化ウェルの画像に焦点を合わる画像取得装置とを含む画像取得光学系と、明領域照射装置と暗領域照射装置を含む光源と、ウェルの内容物の画像化をする前記対物レンズを様々な選択したウェルに対して位置合わせをするために画像取得光学系に対してプレートネストの位置を移動させるネスト位置決めコントローラとを含む。 データベースは、個々の結晶化プレートに関連付けられた実験情報で、固有の識別コードによってデータベース内で個々の結晶化プレートが識別される特定の結晶形成パラメータ値の識別を含む実験情報を蓄積する。 結晶化画像化コントローラは、本装置に挿入された個々の結晶化プレートの情報を検索し、検索された実験情報に基づいてネスト位置決めコントローラと画像取得光学系を制御することにより結晶化画像化を制御する。 本装置は、異なる光源及び偏光条件を用いる個々の結晶サイトの複数画像を取得し、拡大された融合画像を形成するために個々の結晶サイトの複数画像を処理する。
143 Processes and process container with integrated evaporator of evaporation JP2003576101 2003-03-10 JP2005519750A 2005-07-07 アレクザニアン,アラ.ジェイ.; エンゲダール,ジョニイ; カールソン,アーニ; クラウクジイック,マーク,エイ.; ダール,アイバー,エム.
供給原料液体を蒸発させるためのプロセス、及び、液体供給原料を蒸発させるための蒸発ゾーン(18)及びその結果生じた蒸気を処理するための処理ゾーン(26)の両方を含んでいるプロセス容器(10)は、蒸発表面部(82)を用いて液体小滴の形成を防ぐ。 上記装置は、蒸発ゾーン(18)内にあるオリフィス(66)を有する注入器(48)、蒸発ゾーン(18)内に配置されていて供給原料を蒸発させて蒸気を発生させるための少なくとも1つの蒸発表面部(82)、蒸気を処理するための処理ゾーン(26)、及びプロセス容器の少なくとも一部に連結される少なくとも1つの加熱器(20)で構成され、注入器オリフィス及び蒸発表面部(82)は、オリフィス(66)での滴形成を防ぐために配置されることを特徴とする。
144 Protein crystallization condition-screening device JP2003124085 2003-04-28 JP2004194647A 2004-07-15 MOGI ITSURO; MATSUZAKI HIROFUMI; KITAHARA HIDEYOSHI; TSUKAMOTO MITSUHAYA; SHIMOKAWA KOJI; MAGOORI MASAKI; HIGUCHI AKIRA
PROBLEM TO BE SOLVED: To provide a protein crystallization condition-screening device capable of performing the protein crystallization condition screening efficiently a vapor diffusion method by using a sitting drop method. SOLUTION: This protein crystallization condition-screening device capable of performing the protein crystallization condition screening by using the sitting drop method which is a kind of the protein crystallization by using the vapor diffusion method is constituted by joining a crystallization plate-forming device 2 equipped with a separate injection means for separately injecting a protein solution and a crystallization solution into wells of the crystallization plate and a seal-pasting part for tightly closing the injected wells, with a protein crystal-detecting device 5 for detecting the protein crystals in a thermostat chamber for housing the crystallization plate after the injections in a prescribed environment and performing the crystallization plate conveyance automatically to perform the screening automatically in a good efficiency. COPYRIGHT: (C)2004,JPO&NCIPI
145 Method for purifying cyclic ester JP2000096713 2000-03-31 JP2001278877A 2001-10-10 EJIRI TETSUO; YAMANE KAZUYUKI; OTAWARA KENTARO
PROBLEM TO BE SOLVED: To provide a method by which a cyclic ester can simply, efficiently and continuously be purified. SOLUTION: A crude cyclic ester as a raw material crystal is charged into a charging port 3 for the raw material crystal provided in the lower part of a cyclindrical purifying column 1 extending in the vertical direction and stirred while making the raw material ascend with a stirring device 2 arranged in the purifying column 1 and the raw material crystal is purified by countercurrent contact of a descending molten liquid of a purified crystal component with the ascending raw material crystal in the purifying column 1 to take out the crystal after the purification as a product from a takeout port 4 installed in the upper part of the purifying column 1 in the method for purifying the crystal of the cyclic ester. COPYRIGHT: (C)2001,JPO
146 Dry fractionation of oil and fat JP24060297 1997-09-05 JPH1180776A 1999-03-26 YONEDA MAKOTO; HIGUCHI KIYOYUKI; TANIGUCHI ATSUSHI; KUWABARA YUJI
PROBLEM TO BE SOLVED: To make possible to largely save labors and obtain oils and fats stabilized in qualities, because a filter press process can be adopted without sacrificing the yields of high melting point fractions by preliminarily cooling oils and fats and subsequently pouring the oils and the fats into crystallizing trays by a specific method. SOLUTION: Oils and fats as raw materials to be crystallized in a stationary state are preliminarily cooled preferably at a lower temperature by 1 deg.C or larger than a stationary crystallization temperature (the temperature of a cooling medium), divided into small divisions in a large vessel, poured into many crystallization trays disposed in parallel to each other, crystallized in a stationary crystallization state and finally subjected to a solid-liquid separation treatment. Concretely, for example, a large volume vessel 1 in which a plurality of small communicating chambers vertically divided with division plates in a constant height from the bottom and having openings enabling the pouring of the oils and the fats at the upper ends of the chambers are disposed is used. The oils and the fats as the raw materials are introduced into the large volume vessel 1 from an opening 3 for supplying the liquid to be poured. The small chambers are uniformly filled with the oils and fats to divide the oils and the fats into the small portions. Subsequently, the oils and the fats are simultaneously poured into parallel crystallization trays through oil-pouring pipes 5 connected to the bottom portions of the small chambers.
147 Crystallizer JP19904788 1988-08-11 JPH0692437B2 1994-11-16 アンドレアス・プラース‐リンク
148 JPH0153081B2 - JP16210881 1981-10-13 JPH0153081B2 1989-11-13 KURAUSU RATOIEN; MARUTEIN URURITSUHI
The product which is present in the form of a melt is cooled and thereby crystallized in a double-shaft worm machine which has self-cleaning worm shafts rotating in the same direction. The crystallizing material is continually crushed in a repeatedly cutting manner during solidification and during the subsequent cooling operation, while maintaining the main transporting direction in the worm. In this manner, crystal agglomerates are prevented from forming which have only solidified on the surface, while still containing liquid portions inside. The process is carried out using a worm machine, the worm profile of which is repeatedly interrupted by introducing grooves, so that only small segment ridges remain.
149 Vertical vortex cell tower JP4456683 1983-03-18 JPS58174234A 1983-10-13 GEORUKU SHIYURAIBAA; HAINRITSUHI ROOPU
150 Purification of sodium hydroxide JP5067775 1975-04-28 JPS51126399A 1976-11-04 NAKAYA KEIICHI; HIRATA SUEICHI; SATOU KUNIO
PURPOSE: Production of high concentration and high purity sodium hydrizede from its solution containing sodium chloride and other impurities. COPYRIGHT: (C)1976,JPO&Japio
151 Kinzokunorenzokushikirifuratsukusurifuainingu JP11732175 1975-09-30 JPS5176103A 1976-07-01 JEIMUZU DEYURII ESUDEIRU; GUREIMU UIRIAMU WARUTAAZU
152 Crystallization apparatus US229950 1988-08-09 US5009861A 1991-04-23 Andreas Plaas-Link
A crystallization apparatus 2, in particular for crystallizing proteins at zero gravity, comprises a crystallization cell consisting of an elastic tube 8 of which the ends can be sealed. Using a clamp means 10the tube cavity can be reversibly divided into several cells 14, 14', 14" to receive various solutions depending on the particular crystallization.
153 Small volume rotary filter US160693 1988-02-26 US4876013A 1989-10-24 Iosif Shmidt; Mario Badiali
An improved method and apparatus for filtration includes an outer stationary body, an inner rotating body defining a gap with the outer body for receiving a fluid sample, the surface of one of the bodies defining the gap being a filter. The rotation of the inner body creates Taylor vortices which continuously displace occluded solute on the filter surface. The filter can be a membrane. In one embodiment the device may be used to filter very small volumes of fluid such as are handled in clinical and other laboratories.
154 Solvent recovery system US57494 1987-06-03 US4743380A 1988-05-10 Edwin H. Royse
A solvent recovery system (10) is disclosed which separates material from a solution by refrigeration. The solution is used to wash a printing plate and the material is washed from the plate by the solution. The contaminated solution is refrigerated within a disposable container (32) to separate the material from a solution. The purified solution is then drawn off from the container, leaving the material as residue for disposal in the container.
155 Process for purifying sodium hydroxide US901032 1978-04-28 USRE30411E 1980-10-07 Keiichi Nakaya; Suekazu Hirata; Kunio Sato
An aqueous solution of sodium hydroxide containing soluble impurities such as a concentrated catholyte produced by a diaphragm electrolysis is cooled by a coolant or a heat-exchanger to form a slurry containing sodium hydroxide hydrate crystals and fine impurity crystals. The fine impurity crystals are adsorbed on bubbles which are formed by vaporizing a dissolved coolant or introducing a gas in the slurry and separated from the slurry.
156 Continuous reflux refining of metals US808387 1977-06-20 US4133517A 1979-01-09 James D. Esdaile; Graeme W. Walters
A method is provided for the continuous purification of an impure metal in a column consisting of a slurry of metal crystals in liquid metal, said column having a relatively hot zone and a continuous temperature gradient between said zones; the temperature of the cool zone being such as to permit coexistence of liquid and crystalline metal, and said hot zone being at a temperature sufficient to melt the crystals. A portion of the column in the said cool zone is chilled to form a coherent mass of crystals of the metal; then incipient melting in the mass is allowed to occur to release crystals from the mass into the column of the crystals in the liquid metal in the cool zone of said column. The crystals are transported through the temperature gradient and into the hot zone, wherein melting of the crystals occurs and the hot zone thereby becomes enriched with the pure liquid metal.In normal operation, impure feed metal is supplied to the column; purified liquid metal is withdrawn from the hot zone; and impurity-enriched metal is withdrawn from the cool zone.
157 Continuous reflux refining of metals US616816 1975-09-25 US4043802A 1977-08-23 James Durie Esdaile; Graeme William Walters
A method is provided for the continuous purification of an impure metal in a column consisting of a slurry of metal crystals in liquid metal, said column having a relatively hot zone and a continuous temperature gradient between said zones; the temperature of the cool zone being such as to permit coexistence of liquid and crystalline metal, and said hot zone being at a temperature sufficient to melt the crystals. A portion of the column in the said cool zone is chilled to form a coherent mass of crystals of the metal; then incipient melting in the mass is allowed to occur to release crystals from the mass into the column of the crystals in the liquid metal in the cool zone of said column. The crystals are transported through the temperature gradient and into the hot zone, wherein melting of the crystals occurs and the hot zone thereby becomes enriched with the pure liquid metal.In normal operation, impure feed metal is supplied to the column; purified liquid metal is withdrawn from the hot zone; and impurity-enriched metal is withdrawn from the cool zone.
158 Sharpening device for a writing element US3561507D 1968-12-04 US3561507A 1971-02-09 DZIUK PETER
A device for sharpening a writing element mounted in a holder when the writing element is inserted into an eccentric opening in the device and moved in a circular path to rotate a sharpening tool round the element. The opening is formed in a rotary part of a casing and the sharpening tool is carried in a toolholder mounted adjacent said opening, as in a ball-and-socket joint, so that the toolholder may tilt during sharpening and so minimize the danger of breakage of said writing element but the toolholder is held against rotation with the writing element.
159 Crystal growing apparatus US77352758 1958-11-12 US2990258A 1961-06-27 FRANK AUGUSTINE
160 Method of protecting the surfaces of soluble salt crystals US51439855 1955-06-09 US2835606A 1958-05-20 LADD WILLIAM A
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