序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
81 Very high frequency (VHF) driven atmospheric plasma sources and point of use fertigation of irrigation water utilizing plasma production of nitrogen bearing species US14212195 2014-03-14 US09475710B2 2016-10-25 Steven C. Shannon; Detlef Knappe; Brandon Byrns; Daniel Wooten; Alexander Lindsay
A point of use irrigation water fertigation system utilizes plasma production of nitrogen-bearing species. Soluble nitrogen-bearing species are generated using an atmospheric air plasma treatment of an irrigation water supply. A plasma is generated by a tube having an air intake. A high frequency generator generates atmospheric plasma. The end of the tube is placed above the surface of the irrigation water supply and the plasma emanating from the tube generates nitrogen species in the water. The non-thermal plasma discharge efficiently produces highly reactive radicals and NOx species that have impact on water chemistry including inactivation of microorganisms with high efficacy and accelerated removal of persistent organic pollutants such as perfluorinated compounds (PFCs) from water samples. Plasma ignition can be initiated with a low flow of helium gas injection. Upon ignition, the gas is transitioned to a helium/room air mix, immediately followed by a transition to ambient room air only.
82 Cold Plasma Treatment System US15072284 2016-03-16 US20160271412A1 2016-09-22 Robert M. Hummel; Marc C. Jacofsky; Steven A. Myers
A system including a cold plasma treatment system, including a controller configured to produce an electrical signal that generates cold plasma, a cold plasma applicator coupled to the controller, including a roller with at least one cold plasma generating region and at least one massage region, wherein the cold plasma applicator is configured to provide a cold plasma treatment and a massage treatment with the at least one cold plasma generating region and a massage treatment with the at least one massage region.
83 Cold plasma treatment devices and associated methods US13620104 2012-09-14 US09418820B2 2016-08-16 Gregory A. Watson; David J. Jacofsky
A cold plasma helmet application device for delivery of cold plasma benefits to the head of a patient. An appropriate gas is introduced into a helmet receptacle within a containment dome of the helmet. The gas is energized by one or more dielectric barrier devices that receive energy from a pulsed source. The dielectric barrier devices can be configured to match the treatment area. Such a device and method can be used to treat large surface areas treatment sites associated with the head, head trauma, brain cancer, the control of brain swelling with closed head injury or infection, as well as treating male pattern baldness.
84 DEVICE FOR THE PLANAR TREATMENT OF AREAS OF HUMAN OR ANIMAL SKIN OR MUCOUS MEMBRANE SURFACES BY MEANS OF A COLD ATMOSPHERIC PRESSURE PLASMA US14732387 2015-06-05 US20160045246A1 2016-02-18 Manfred STIEBER; Klaus-Dieter WELTMANN; Stefan HORN; Ronny BRANDENBURG; Thomas VON WOEDTKE
The invention relates to a device, preferably a collar, for treating areas of human or animal skin or mucous membrane with a cold atmospheric pressure plasma by creating a dielectrically hindered surface discharge, comprising at least one flexible insulating material (1), a flexible high-voltage electrode (2), a flexible dielectric (3), a flexible grounded electrode (4) and a gas supply (7), characterized in that the flexible high-voltage electrode (2) is embedded in the insulating elastomer (3), having the effect of a dielectric, and the grounded electrode (4) is applied to the elastomer surface facing the surface to be treated.
85 COLD PLASMA SEED TREATMENT DEVICE US14649295 2013-03-28 US20150327430A1 2015-11-19 Yuanhua DONG; Hanliang Shao; Qin Miao; Haibo Qian
Disclosed is a cold plasma seed treatment device, having a vacuum apparatus, an electric discharging apparatus, and a transport apparatus. The electric discharging apparatus and the transport apparatus are disposed in the vacuum apparatus. The vacuum apparatus is provided with a tube feeding hole and a tube discharging hole. The cold plasma seed treatment device further has a feeding apparatus and a discharging apparatus. The feeding apparatus comprises a first feeding hopper and a second feeding hopper, each of which is provided with a feeding cover, a vent valve, a discharging hole, and a vacuuming butterfly valve. Each of the discharging hole of the feeding hopper and the tube feeding hole are separately connected to a three-way pipe by using a butterfly valve. Each vacuuming butterfly valve is connected to a first vacuuming pump group. The discharging apparatus comprises a first discharging hopper and a second discharging hopper.
86 WOUND HEALING DEVICE US14795221 2015-07-09 US20150314036A1 2015-11-05 Joe O'Keeffe; Peter Dobbyn; John O'Donoghue; Liam O'Neil
A plasma coating device for treating a wound comprises a plasma chamber having: one or more electrodes, a gas supply inlet, a plasma outlet exposed to ambient pressure, and an ignition system operatively connected to the electrodes for providing a non-thermal equilibrium plasma within the plasma chamber. An aerosol delivery system is operable to introduce a bioresorbable material as an aerosol into the plasma, to produce a coating on the wound surface.
87 TRANSDERMAL DELIVERY OF DNA VACCINES USING NON-THERMAL PLASMA US14560343 2014-12-04 US20150151135A1 2015-06-04 Sameer Kalghatgi; Daphne Pappas Antonakas; Tsung-Chan Tsai; Robert L. Gray
Exemplary systems and methods of delivering DNA vaccines are disclosed herein. An exemplary methodology of delivering DNA vaccines includes providing a plasma generator for applying plasma to a treatment area for a sufficient period of time to open one or more pores. Applying a topical DNA vaccine to the treatment area and waiting for a period of time to allow the DNA vaccine to travel through the one or more pores. The exemplary methodology further includes applying plasma to the treatment area at a setting sufficient to cause intracellular uptake of the DNA vaccine.
88 Device for generating cold plasma in a vacuum chamber and use of said device for thermo-chemical processing US12526904 2008-02-01 US09011655B2 2015-04-21 Philippe Maurin-Perrier; Hervé Chavanne; Laure Poigt
A device for generating a cold plasma in a vacuum enclosure includes a cathode body having hollow chambers for confining the plasma. Magnets are placed around each hollow chamber for creating a magnetic field forcing electrons to rotate about the field lines. The cathode body cooperates with an element for circulating a coolant to extract the heat generated by an intense ion bombardment at each of the hollow chambers.
89 PHYSICAL MEANS AND METHODS FOR INDUCING REGENERATIVE EFFECTS ON LIVING TISSUES AND FLUIDS US14525802 2014-10-28 US20150105716A1 2015-04-16 Orit ISH-YAMINI TOMER; Tamar Levin
A system for the administration of modified plasma to a subject, including: (a) a non thermal plasma (NTP) emitting source for emitting a plasma beam; (b) a plasma coupling mechanism (PCM) with a plasma beam dish having at least one opening for the passage of the plasma beam; the plasma beam dish having a first surface and a second opposite surface. The first surface of the plasma beam dish includes: at least one coupling element selected from the group consisting of: (1) at least one ferroelectric element for providing the field; (2) at least one ferromagnetic element for providing the field; (3) at least one piezoelectric element for providing the field; and (4) at least one piezomagnetic element for providing the field. The system additionally includes at least one reflecting element configured to focus the NTP beam, thereby providing the modified plasma.
90 Cold plasma treatment devices and associated methods US13620118 2012-09-14 US09006976B2 2015-04-14 Gregory A. Watson; Robert M. Hummel; Marc C. Jacofsky; David J. Jacofsky
A compact cold plasma device for generating cold plasma having temperatures in the range 65 to 120 degrees Fahrenheit. The compact cold plasma device has a magnet-free configuration and an induction-grid-free configuration. An additional configuration uses an induction grid in place of the input electrode to generate the cold plasma. A high voltage power supply is provided that includes a controllable switch to release energy from a capacitor bank to a dual resonance RF transformer. A controller adjusts the energy input to the capacitor bank, as well as the trigger to the controllable switch.
91 Cold plasma treatment devices and associated methods US13620224 2012-09-14 US08928230B2 2015-01-06 Gregory A. Watson; Marc C. Jacofsky
A cold plasma treatment device for delivery of a cold plasma to patient treatment area. Gas is fed to a gas compartment where it is energized by an electrode coupled to a pulse source to thereby generate a cold plasma. A dielectric barrier is sandwiched between the gas compartment and the electrode to form a dielectric barrier discharge device. The cold plasma exits the gas compartment via a bottom member having a plurality of holes. Gases that can be used include noble gases such as helium or combinations of noble gases.
92 Device for generating gaseous species US13510030 2010-11-11 US08828326B2 2014-09-09 Thomas Bickford Holbeche
The present invention provides a device 10 for generating a non-thermal gaseous plasma which may be a flow of gas plasma in the form of a gas plasma plume emitted from the device. The device comprises a gas capsule, or pressure vessel, 12 for holding a gas or gases 14 under pressure and forming a flow of gas through a plasma generator 16 to an applicator 18 when released from the capsule. Gas released from the gas capsule is energised in the reaction generator to form a gas plasma.The device has a housing 28 for the plasma generator 16, a battery 116 and a signal generator 58 for energising the plasma generator. The gas capsule 12 docks with the housing 28. The device is adapted to be hand-held, typically by the gas capsule 12, and operated to allow it to be used for instance for cleaning and whitening teeth.
93 PHYSICAL MEANS AND METHODS FOR INDUCING REGENERATIVE EFFECTS ON LIVING TISSUES AND FLUIDS US13874547 2013-05-01 US20140199756A1 2014-07-17 Orit ISH-YAMINI TOMER; Tamar LEVIN
The present invention discloses a system for the administration of a plasma modified field (PMF) to a subject comprising: (a) a non thermal plasma (NTP) emitting source for emitting a plasma beam; (b) a plasma modified field coupling mechanism (PMFCM) comprising a plasma beam dish having at least one opening for the passage of said plasma beam; said plasma beam dish having a first surface and a second opposite surface; and (c) a controller for controlling said PMFCM. In a main aspect of the invention, said first surface of said plasma beam dish is mounted with: (i) at least one coupling element selected from the group consisting of: (1) at least one ferroelectric element for providing said field; (2) at least one ferromagnetic element for providing said field; (3) at least one piezoelectric element for providing said field; and (4) at least one piezomagnetic element for providing said field; and (ii) at least one reflecting element. In a further main aspect, the PMFCM and said controller are configured to adjust any of said at least one coupling and reflecting element in a predetermined manner thereby providing said PMF for inducing a therapeutic or regenerative or beneficial effect on said subject. The present invention further discloses methods and use of the aforementioned system.
94 Low temperature plasma probe and methods of use thereof US14010130 2013-08-26 US08772710B2 2014-07-08 Zheng Ouyang; Jason Harper; Nicholas Charipar; Robert Graham Cooks
The present invention generally relates to a low temperature plasma probe for desorbing and ionizing at least one analyte in a sample material and methods of use thereof. In one embodiment, the invention generally relates to a low temperature plasma probe including: a housing having a discharge gas inlet port, a probe tip, two electrodes, and a dielectric barrier, in which the two electrodes are separated by the dielectric barrier, in which application of voltage from a power supply generates a low temperature plasma, and in which the low temperature plasma is propelled out of the discharge region by the electric field and/or the discharge gas flow.
95 Cold Plasma Electroporation of Medication and Associated Methods US14145320 2013-12-31 US20140188071A1 2014-07-03 Marc C. Jacofsky; David J. Jacofsky; Gregory A. Watson
A method and device to apply a cold plasma to a substance at a treatment surface of a patient to cause electroporation of the substance into cells of the patient. The substance can be previously applied to the treatment surface. Alternatively, the substance can be placed in a foam-like material within a tip that passes the cold plasma from the cold plasma device to the treatment area. The tip can be a cannula device with an aperture at the distal end. The cannula device can also have apertures along a portion of the length of the cannula device.
96 Treatment device US13510024 2010-11-11 US08651120B2 2014-02-18 Cormac John Devery; Thomas Bickford Holbeche; Geoffrey Morgan Lloyd
An interdental treatment device comprises a generator 16 for generating a non-thermal gaseous plasma at a temperature suitable for use in oral treatment and an applicator 18 of the non-thermal plasma. The applicator 18 may comprise a hollow needle member for directing a jet of the non-thermal plasma interdentally. Alternatively the applicator 18 may comprise an interdental brush having a hollow head for receiving a non-thermal gaseous plasma, the head having at least one lateral opening for the discharge of the plasma. The generator 16 and applicator 18 may both form part of a hand-held device 10 having its own gas supply in the form of a capsule 12 containing pressurized gas and its own power supply in the form of a battery 20.
97 Low temperature plasma generator US12583222 2009-08-17 US08460283B1 2013-06-11 Mounir Laroussi; Julien Jarrige
A plasma generator having a dielectric body; a first end wall and a second end wall attached or coupled to each end of the dielectric body to define a cavity within the dielectric body, and wherein the second end wall includes at least one discharge aperture formed therein; at least one gas inlet formed proximate the first end of the dielectric body; at least one anode located within the cavity of the dielectric body, wherein the at least one anode includes at least one anode aperture; at least one hollow discharge nozzle associated with each discharge aperture, and extending from the second end wall to a nozzle aperture, such that when a generated plasma is produced, the generated plasma flows through each discharge aperture, each associated discharge nozzles, and each associated nozzle aperture; and at least one cathode formed at least substantially around a portion of each discharge nozzle.
98 Cold Plasma Treatment Devices and Associated Methods US13620092 2012-09-14 US20130072858A1 2013-03-21 Gregory A. Watson; Robert M. Hummel; Marc C. Jacofsky; David J. Jacofsky
A cold plasma mask application device for delivery of a cold plasma to the face of a patient. An appropriate gas is introduced into a gas containment area that is energized by one or more electrodes that receive energy from a pulsed source. The plasma can be prevented from contact with the patient's face, or can be allowed to make contact with the patient's face at the appropriate treatment area. A three-layer approach to the manufacture of the cold plasma mask application device is also described. Such a device and method can be used to treat acne as well as complex facial wounds such as those resulting from trauma, melanoma, and other cancers of the face, rosacea, and psoriasis.
99 Harmonic Cold Plasma Devices and Associated Methods US13620132 2012-09-14 US20130069530A1 2013-03-21 Gregory A. WATSON; Robert M. HUMMEL; Marc C. JACOFSKY; David J. JACOFSKY
A gas cartridge is described that is configured to provide sufficient gas to support cold plasma generation for a specific medical process. The gas cartridge has a seal that is pierced upon connection of the gas cartridge to the cold plasma delivery system. Different embodiments are described that use different connection locations between the gas cartridge and the cold plasma delivery system. A shroud is also described that shields the user if the cold plasma delivery system is dropped and the gas cartridge ruptures. Use of an ID system assists in ensuring that the correct gas mixture, correct gas cartridge and correct power supply settings are used for the particular medical treatment process.
100 Cold Plasma Treatment Devices and Associated Methods US13620205 2012-09-14 US20130068226A1 2013-03-21 Gregory A. WATSON; Marc C. Jacofsky
An inhalable cold plasma mask device for generation of a breathable cold plasma for delivery to a patient. A biocompatible gas is received in a dielectric barrier discharge (DBD) device that is energized by an electrode that receives energy from a pulsed source. The DBD device can be grounded by a grounding structure. A grounding screen can be used prior to inhalation of the cold plasma. The inhalable cold plasma mask device includes the use of a single-layer or a two-layer approach to its construction. The inhalable cold plasma mask device can have one or two DBD devices. Such a device and associated method can be used to treat upper respiratory tract infections, as well as reducing inflammation, sinus and esophageal polyps in both size and frequency of occurrence.
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