首页 / 国际专利分类库 / 物理 / 测量 / 借助于测定材料的化学或物理性质来测试或分析材料 / 测试颗粒的特性;测试多孔材料的渗透性,孔隙体积或表面积(微生物的识别入C12Q)
序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
181 JPS5853860B2 - JP13062478 1978-10-24 JPS5853860B2 1983-12-01 MATSUMURA TAKAO; SHIMANUKI KOJI; HASEGAWA SHIRO
182 JPS5744136B2 - JP6100978 1978-05-24 JPS5744136B2 1982-09-20
183 Live Single-Cell Bioassay in Microdroplets US15965841 2018-04-27 US20180313844A1 2018-11-01 Tania KONRY; Saheli SARKAR; Pooja SABHACHANDANI
Bioassays are provided for detecting and analyzing responses from single cells and cell pairs suspended in micro-scale droplets (80-200 μm diameter) generated in microfluidic devices. Cell responses to various stimuli are analyzed. The stimuli are delivered by homotypic or heterotypic cells, small molecule drugs, and therapeutic agents including immunotherapeutics. The bioassays can be used to describe heterogeneity in any given cell population, and can be used in a clinical setting, such as profiling of patient-derived cells, designing personalized treatment strategies, and optimizing drug combinations for immunotherapy of tumors.
184 APPARATUS FOR ANALYZING A SAMPLE OF GRANULAR MATERIAL US15964972 2018-04-27 US20180313747A1 2018-11-01 Viacheslav ADAMCHUK; Asim BISWAS; Long QI; Maxime LACLERC; Bharath SUDARSAN; Wenjun JI
An apparatus for analysing a sample of granular material, such as soil, is described. An elongated housing has a channel extending therethrough to define an optical path. A cavity is defined within the top of the housing to receive the sample, and a transparent sample-receiving surface is disposed within the cavity at a first elevation from the bottom of the housing. A lens assembly is positioned within the optical path at a second, lower, elevation. The lens assembly magnifies an image formed by light beams reflected by or transmitted through the sample. An image capturing device is disposed across the optical path at a third elevation that is lower than the second elevation. The image capturing device is thus lower than both the lens assembly and the transparent sample-receiving surface. A light source is mounted within the housing to emit light toward the sample-receiving surface.
185 NEAR-INFRARED RAY EXPOSURE SYSTEM FOR BIOLOGICAL STUDIES US15491137 2017-04-19 US20180305679A1 2018-10-25 Vidya Sagar; Madhavan Nair
An apparatus and methods of using the same for conducting photonic and optical treatments on biological samples with additional functions including temperature monitoring and real-time microscopic imaging are provided. The photonic and optical treatments can be conducted using light with wavelengths in the near-infrared region (NIR) on biological samples, including in-vitro brain cell cultures, in-vivo central nervous system (CNS) and peripheral nervous system (PNS) tissue samples, and other body tissues. The apparatus and methods can be combined with magnetic nanoparticles treatment to accomplish non-invasive, on-demand drug targeting, brain cell specific gene delivery, and magnetized photo-biomodulation for treating various CNS disorders.
186 Methods and devices for sorting cells and other biological particulates US14743542 2015-06-18 US10105712B2 2018-10-23 Maurice M. Garcia; Aaron Ohta; Ming Wu; Tom F. Lue; Justin Valley
An optical pattern-driven light induced dielectrophoresis (DEP) apparatus and separation methods are described which provide for the manipulation of particles or cells and selection based on traits correlated with the DEP response. Embodiments of the apparatus use DEP electric field patterns in combination with microfluidic laminar flows to measure response, separate, segregate and extract particles from heterogeneous mixtures according to the relative response of the particles to one or more DEP fields without damaging living cells. The preferred OET-DEP devices generally comprise a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a localized virtual electrode with a DEP electric field gradient of selected intensity along with input and a plurality of output fluidic channels. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or groups of particles/cells. The methods are particularly suited for selecting and extracting the best sperm and embryo candidates based on fitness for use with existing artificial reproduction procedures and excluding defective or non-viable gametes.
187 SCREENING OF NANOPARTICLE PROPERTIES US15571808 2016-04-29 US20180266932A1 2018-09-20 Andrea VALSESIA; Cloé DESMET; Pascal COLPO; François ROSSI
A nanoparticle screening chip and a method using said chip allowing for determining physical properties of nanoparticles, wherein the screening chip comprises a substrate having a working surface divided into a plurality of areas, wherein (1) each of these areas presents different surface properties defined by surface energy component (d,b,a), the total free energy γTOT of the surface of each area being defined as follows: γTOT=γLW+2(γ+γ−)0.5, wherein the components are: γLW=dispersive component=d, γ+=electron acceptor component=b, γ−=electron donor component=a; and (2) each of these areas comprises a plurality of subareas, each subarea comprising an array of sub-micrometric holes or elongated grooves with a different aperture size (S1, S2, S3, . . . ).
188 METHOD AND SYSTEM FOR IN-LINE ANALYSIS OF PRODUCTS US15317847 2015-06-12 US20180259446A1 2018-09-13 Max Terry COFFEY; Cristina Ellen PHILLIPS; Jeffery Alan HANSEN
The present invention is drawn to methods and systems for using in-line near infrared spectroscopy to determine the physical parameters of a comminuted product.
189 OPTICAL SENSOR US15428511 2017-02-09 US20180224327A1 2018-08-09 Stefan Abel; Jean Fompeyrine; Antonio La Porta
An optical sensor includes an interaction region configured to comprise an analyte and an illumination source configured to illuminate the interaction region with an optical input signal. The optical sensor further includes an optical coupling structure configured to collect transmitted parts of the optical input signal from the interaction region and an optical neuromorphic network that is directly optically coupled to the optical coupling structure and is configured to receive and process the transmitted parts of the optical input signal in the optical domain. The invention further concerns a related method for analyzing an analyte by an optical sensor.
190 APPARATUS AND METHOD FOR OPTICALLY MEASURING FLUIDAL MATTER HAVING FLUID AS MEDIUM AND PARTICLES NON-DISSOLVED IN MEDIUM US15836277 2017-12-08 US20180172585A1 2018-06-21 Pasi KÄRKI
An apparatus for optically measuring fluidal matter having fluid as medium and particles non-dissolved in the medium wherein the apparatus comprises a measurement chamber, which is configured to contain the fluidal matter, and a nozzle. The nozzle receives flowable matter and emits a jet of the flowable matter towards or fromwards an optical detector which is associated with the measurement chamber and receives optical radiation from the fluidal matter in the measurement chamber.
191 INSPECTION DEVICE, INSPECTION SYSTEM, AND INSPECTION METHOD US15578193 2016-10-05 US20180149601A1 2018-05-31 Takaharu ENJOJI; Yoshikazu WAKIZAKA; Satoshi UCHIDA; Eiko KATO; Masayo TAKANO
An inspection device (1) inspects an amount of dielectric particles contained in a sample liquid. The inspection device includes a dielectric collection unit (3), a pump unit (10) and an AC voltage supply unit (11). The dielectric collection unit includes at least one pair of electrodes (41, 42) and a flow channel (13) extending in a predetermined direction on the pair of electrodes. The pump unit is configured to feed the sample liquid to follow the flow channel in the predetermined direction. The AC voltage supply unit is configured to supply, to the pair of electrodes, an AC voltage with a predetermined frequency to cause dielectrophoresis for dielectric particles in the fed sample liquid. The dielectric collection unit includes a plurality of slit regions (Rs) aligned in the predetermined direction between the pair of electrodes. Each of the plurality of slit regions is separated from each other within the flow channel.
192 Method and system for exhaust particulate matter sensing US14937632 2015-11-10 US09951672B2 2018-04-24 David Bilby
Methods and systems are provided for sensing particulate matter by a particulate matter sensor positioned downstream of a diesel particulate filter in an exhaust system. In one example, a method may include accumulating incoming particulate matter by applying a higher bias to a first trap of the particulate matter sensor, and further charging the particulate matter and forming highly charged dendrites. The method further includes capturing the dendrites exiting the first trap by applying a lower bias to a second trap also housed within the same particulate matter sensor, thereby reducing the effects of exhaust flow rate on the particulate matter sensor and further increasing the sensitivity of the particulate matter sensor.
193 SURFACE CHARGE MEASUREMENT US15789984 2017-10-21 US20180059160A1 2018-03-01 Jason Corbett; Fraser McNeil-Watson; Robert Jack
The invention relates to methods and apparatus for determining properties of a surface. Embodiments disclosed include an apparatus for measuring a surface charge of a sample, comprising: a sample holder having an opposed pair of electrodes and configured to hold a sample in position in a measurement volume between the electrodes such that a planar surface of the sample is aligned orthogonal to the electrode surfaces; a measurement chamber for containing a measurement liquid and having an open end configured to receive the sample holder to position the electrodes in a preset orientation; a laser light source positioned and configured to direct a laser beam through the measurement chamber between the electrodes and parallel to the planar surface of the sample when the sample holder is received in the measurement chamber; and a detector positioned and configured to detect scattered light from the measurement volume, wherein the apparatus is configured to allow for detection of the scattered light by the detector over a range of distances from the surface of the sample.
194 Evaluation of fluid-particle mixtures based on dielectric measurements US14032076 2013-09-19 US09891153B2 2018-02-13 Mustapha Abbad; Khaled Hadj-Sassi; Stephen Dyer
A system is described for evaluating coagulation of particles in a downhole fluid-particle mixture based on dielectric measurements. An example downhole treatment is one in which flocs are used to plug a high-permeability subterranean formation zone as part of a stimulation procedure. An injection tube is positioned within the wellbore to the high-permeability zone. An instrumented section of tubing includes one or more dielectric probes that are positioned and configured to make dielectric measurements of the particle-fluid mixture flowing in the tubing or in the annulus. The downhole dielectric measurements are used to indicate whether or not the particle-fluid mixture has the desired structural properties. An operator on the surface can make adjustments in real-time according to the received dielectric measurements.
195 Particle sensor US15388614 2016-12-22 US09885602B2 2018-02-06 Hirotaka Matsunami; Shintaro Hayashi; Shinichi Kitaoka
A particle sensor is provided. The particle sensor includes a light projector that projects light to a detection area. A light receiver receives scattered light. The scattered light is light from the light projector that has been scattered by particles in the detection area. A first support supports the light receiver. A second support supports the light projector and has a linear expansion coefficient different from a linear expansion coefficient of the first support. The first support includes a first placement region in which the light receiver is disposed and a second placement region in which the second support is disposed. The first placement region and the second placement region are located at different distances from at least one of an optical axis of the light projector and an optical axis of the light receiver.
196 Microparticle detection device and security gate US14402959 2013-04-30 US09850696B2 2017-12-26 Masakazu Sugaya; Koichi Terada; Hideo Kashima; Yasuaki Takada; Hisashi Nagano
In a conventional fine particle detection device that vaporizes fine particles attached to the object of examination by heating, processing capability decreases as the processing time elapses due to the influence of deposition of fine particles other than the object of examination, dirt/dust, a residue of the fine particles as the object of examination, or residual matter. A fine particle detection device according to the present invention includes: a vaporization device that vaporizes the fine particles trapped by a trap device by vaporization or decomposition; a first flow passageway in which a mixture of a component vaporized by the vaporization device and another component flows; a second flow passageway branching from the first flow passageway in a direction of inertial force acting on the other component; a third flow passageway branching from the first flow passageway in a direction different from the direction of the inertial force; and an analysis device that analyzes a component introduced into the third flow passageway.
197 Surface charge measurement US14126673 2012-06-13 US09829525B2 2017-11-28 Jason Corbett; Fraser McNeil-Watson; Robert Jack
The invention relates to methods and apparatus for determining properties of a surface. Embodiments disclosed include an apparatus for measuring a surface charge of a sample, comprising: a sample holder having an opposed pair of electrodes and configured to hold a sample in position in a measurement volume between the electrodes such that a planar surface of the sample is aligned orthogonal to the electrode surfaces; a measurement chamber for containing a measurement liquid and having an open end configured to receive the sample holder to position the electrodes in a preset orientation; a laser light source positioned and configured to direct a laser beam through the measurement chamber between the electrodes and parallel to the planar surface of the sample when the sample holder is received in the measurement chamber; and a detector positioned and configured to detect scattered light from the measurement volume, wherein the apparatus is configured to allow for detection of the scattered light by the detector over a range of distances from the surface of the sample.
198 Recycle Diluent For Wellbore Fluid Sampling System US15525525 2014-12-23 US20170321505A1 2017-11-09 Robert J. Murphy; Sandeep D. Kulkarni
A wellbore fluid sampling system and method of operation are provided. A wellbore fluid sampling system may comprise a mixing system coupled to a wellbore sample supply and a recycled diluent supply, a fluid analysis system coupled to the mixing system, and a diluent recycle system coupled to the fluid analysis system and the mixing system, wherein the diluent recycle system comprises an evaporator and a condenser. A method for recycling diluent may comprise combining a wellbore fluid sample with a diluent to form a diluted wellbore fluid sample, analyzing the diluted wellbore fluid sample to determine one or more fluid properties, separating at least a portion of the diluent from the wellbore fluid sample in the diluted wellbore fluid sample, and recycling the separated portion of the diluent for re-use.
199 PARTICLE SENSING DEVICE AND ELECTRONIC APPARATUS HAVING THE SAME US15252245 2016-08-31 US20170292912A1 2017-10-12 Yu-Hsuan Ho; Yi-Der Wu
A particle sensing device, which senses a particulate matter by using a light beam from a light source, is provided. The particle sensing device includes a columnar array and a light-sensing element. The columnar array is disposed at a downstream side of a traveling path of the light beam. The columnar array has a plurality of columnar objects. A gap is existed between two adjacent columnar objects. The light-sensing element is disposed opposite to the columnar array and at a downstream side of a traveling path of the light beam. Wherein, the traveling path of the light beam is parallel with a length direction of each columnar object. And, the light beam passes through the gap for arriving at the light-sensing element. The particle sensing device can sense the particulate matter satisfactorily and can be simply integrated into various electronic apparatuses.
200 LIQUID-SAMPLE COMPONENT ANALYSIS METHOD US15611265 2017-06-01 US20170269071A1 2017-09-21 Akira SATO
A liquid-sample component analysis method includes a dripping step of dripping a liquid sample onto a flat horizontal surface, a drying step of drying a liquid droplet of the liquid sample formed on the horizontal surface while keeping the liquid droplet still so as to obtain a plurality of concentrically-arranged ring-shaped deposits formed on the horizontal surface and composed of components having different particle diameters, and a measuring step of measuring a vibrational spectrum in each region including only one of the deposits so as to individually acquire vibrational spectra of the plurality of deposits.
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