序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
101 TINTING HYDROGEL MATERIALS WITH VAT DYES EP95921509.0 1995-05-26 EP0764190A1 1997-03-26 EVANS, John, M.
Disclosed are processes for tinting hydrogel materials, such as contact lenses, by dissolving a leuco sulfate ester of a vat dye in a compatible monomer solution, adding an oxidizing initiator to the monomer solution, and oxidizing and polymerizing the monomer solution and dye in the same solution. In one aspect, the oxidation and polymerization are conducted simultaneously whereas in another embodiment, the oxidation of the soluble leuco sulfate ester of a vat dye to the insoluble vat dye and polymerization are conducted sequentially in the same reaction medium.
102 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES PCT/US2005036571 2005-10-11 WO2006044413B1 2006-08-10 HOFFACKER KURT D; LUGADE ANANDA G; TERPETSCHNIG EWALD
Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.
103 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES PCT/US2005036571 2005-10-11 WO2006044413A3 2006-06-22 HOFFACKER KURT D; LUGADE ANANDA G; TERPETSCHNIG EWALD
Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.
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