序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase US14581592 2014-12-23 US09271970B2 2016-03-01 Danny Ng; Michael P. Arend; Lee A. Flippin
The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
2 Naphthyridine derivatives as inhibitors of Hypoxia inducible factor (HIF) hydroxylase US15043286 2016-02-12 US09695170B2 2017-07-04 Danny Ng; Michael P. Arend; Lee A. Flippin
The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
3 NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) HYDROXYLASE US15043286 2016-02-12 US20160159796A1 2016-06-09 Danny Ng; Michael P. Arend; Lee A. Flippin
The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
4 NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) HYDROXYLASE US14581592 2014-12-23 US20150174110A1 2015-06-25 Danny Ng; Michael P. Arend; Lee A. Flippin
The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
5 Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase US13983025 2012-02-01 US08921389B2 2014-12-30 Danny Ng; Michael P. Arend; Lee A. Flippin
The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
6 NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) HYDROXYLASE US13983025 2012-02-01 US20140088101A1 2014-03-27 Danny Ng; Michael P. Arend; Lee A. Flippin
The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
7 NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) HYDROXYLASE EP12704581.3 2012-02-01 EP2670750A1 2013-12-11 NG, Danny; AREND, Michael P.; FLIPPIN, Lee A.
The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
8 NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF HYPOXIA INDUCIBLE FACTOR EP12704581.3 2012-02-01 EP2670750B1 2016-09-14 NG, Danny; AREND, Michael P.; FLIPPIN, Lee A.
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