| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 181 | Digestive, and immune - the use of Bacillus pb6 for the prevention or treatment of related diseases | JP2008543436 | 2006-11-29 | JP5280854B2 | 2013-09-04 | サス，ベネディクト; ヴァン・ヘーメル，ヨハン; ヴァンデンケルックホーブ，ヤン; ペイス，エリック; タン，ハイ・メン; セ，チー−ユン; ラムチャンド，チャニイルパランプ; ヴァーゲセ，ジェリー |
| Bacteria of the sp. Bacillus that produce a lipopeptide are found to be effective in the treatment and prophylaxis of gastro-intestinal disease when administered as a probiotic. In particular, a strain of Bacillus bacteria identified as PB6 is useful for the treatment of Antibiotic Associated Diarrhea (AAD) or the more serious condition Clostridium difficile associated diarrhea (CDAD) when administered as a probiotic. Additionally, these bacteria have been found efficient for the treatment of immunorelated diseases such as Inflammatory Bowel Disease (IBD). | ||||||
| 182 | Bile resistant Bacillus composition | JP2011541411 | 2009-12-16 | JP2012512639A | 2012-06-07 | クナレボルウ アネ; クナップ インゲ; デュルマン レセール トマス; デルクス パトリック; ルン ベンテ; ディネス カントル メッテ |
| 胆汁酸塩（擬似的消化管環境）中で急速に発芽および成長すること、および目的の化合物を生産すること、を特徴とするバチルス組成物。 当該バチルス組成物は、動物用飼料中の添加物として用いることができ、飼料中にて、プロバイオティック（健康増進）効果を有し、消化を促進して動物用飼料の栄養分の有効性を高める。 | ||||||
| 183 | New natto and natto produced using this | JP2011198971 | 2011-09-13 | JP4918173B1 | 2012-04-18 | ケイ子 吉原; 典永 奥畑; 由子 林; 杉夫 渡辺; 吉弘 牛久 |
| 【課題】 粘質性と納豆臭の減少化が図られる納豆を得ること。
【解決手段】 バチルス・ズブチルス（Bacillus subtilis）AZ-5512菌株（FERM P-22135）及びこの菌株を用いて製造した納豆である。 【選択図】 図２ |
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| 184 | Thiamine production by fermentation | JP2006508093 | 2004-05-27 | JP4695068B2 | 2011-06-08 | ゲーゼ，マルクス・ギュンター; シンス，ギスラン; パーキンス，ジョン・ビー |
| 185 | Increased protein expression in Bacillus | JP2003580558 | 2003-03-28 | JP4680512B2 | 2011-05-11 | ウェイラー、ウォルター; ハービソン、キャロル; フェラーリ、ユージニオ; ラシード、エム・ハルニュアー |
| The present invention provides cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms, such as Bacillus species having enhanced expression of a protein of interest, wherein one or more chromosomal genes have been inactivated, and preferably wherein one or more chromosomal genes have been deleted from the Bacillus chromosome. In some further embodiments, one or more indigenous chromosomal regions have been deleted from a corresponding wild-type Bacillus host chromosome. | ||||||
| 186 | Dioxins extermination accelerator | JP2004508827 | 2003-05-30 | JP4652050B2 | 2011-03-16 | 宏 吉川; 明弘 増山; 英利 森田; 直 篠田 |
| An accelerating agent for elimination of dioxins which comprises, as an active ingredient, a microorganism having an activity of accelerating elimination of dioxins in the body to the outside of the body. | ||||||
| 187 | New bacillus natto and soft fermented soybeans produced by using the bacillus natto | JP2007115110 | 2007-04-25 | JP2008263929A | 2008-11-06 | TAKEMURA HIROSHI |
| <P>PROBLEM TO BE SOLVED: To obtain Bacillus natto suitable for producing soft fermented soybeans. <P>SOLUTION: The Bacillus natto suitable for producing soft fermented soybeans is obtained by separating Bacillus natto from Chungkookjang being a fermented food used for food in Korea and separating Bacillus natto by using thread pulling and hardness of fermented soybeans as indexes. The Bacillus natto is different from existing Bacillus natto and has characteristics of softening fermented soybeans with progress of fermentation. The method for producing softer fermented soybeans comprises using the Bacillus natto. The soft fermented soybeans are produced by the production method. <P>COPYRIGHT: (C)2009,JPO&INPIT | ||||||
| 188 | Method for controlling plant disease using the Bacillus subtilis strains with antagonism | JP2007504884 | 2005-03-23 | JP2007530032A | 2007-11-01 | キム、ジン−チョル; ジャン、キュン−ソ; チョ、クワン−ユン; チョイ、ギュン−ジャ; チョイ、ヨン・ホ; リ、ソン−ウォ; リム、ヘ−キュン |
| 【課題】 植物病に対する拮抗作用を有する新規な枯草菌株、これを含む植物病防除用の微生物製剤、及び該微生物製剤を用いて植物病を生物学的に防除する方法を提供する。
【解決手段】 本発明による新規な枯草菌（Bacillus subtilis）ＥＢ１２０菌株は、オオムギうどん粉病、キュウリうどん粉病、トウガラシ炭疽病、イネいもち病、トマト灰色かび病、トマト疫病、及び小麦赤さび病を含む多様な植物病の防除のための強い拮抗作用を有するので、植物病の生物学的な防除に有用である。 【選択図】 図１ |
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| 189 | Thiamine production by fermentation | JP2006508093 | 2004-05-27 | JP2006526395A | 2006-11-24 | ゲーゼ，マルクス・ギュンター; シンス，ギスラン; パーキンス，ジョン・ビー |
| 本発明は、チアミン産物を過剰産生させそしてチアミン産物を培地中に放出させる突然変異を含む微生物を使用して、チアミン産物を産生させる方法を提供する。 この突然変異を含む微生物の生物学的に純粋な培養物及びこの突然変異を含む単離されたポリヌクレオチドも提供される。 更に、臨床サンプル中の病原性微生物を検出する方法、抗生物質を同定するためのアッセイ、並びにこのようなアッセイにより同定された抗生物質が提供される。 | ||||||
| 190 | Microorganisms and the use of new species | JP2000593726 | 1999-01-14 | JP3789303B2 | 2006-06-21 | 武三 青沼 |
| 191 | Non-sporulating Bacillus subtilis portion of the gene encoding the sigma g is missing | JP2003542599 | 2002-11-05 | JP2005508184A | 2005-03-31 | スサンナ・ケーリエイネン; ペルッティ・コスキ |
| 本発明は、非胞子形成枯草菌株、その調製方法およびその産生生物としての使用に関する。 さらに、本発明は該非胞子形成細菌により生物学的に調製される産物の調製方法に関する。 | ||||||
| 192 | Microorganism which produces riboflavin and method for producing the riboflavin by using the same | JP2003142502 | 2003-05-20 | JP2004180672A | 2004-07-02 | LEE KWANG HO; PARK YOUNG HOON; HAN JONG KWON; PARK JANG HEE; LEE KYUNG HAN; CHOI HYANG |
| PROBLEM TO BE SOLVED: To provide Bacillus subtilis which produces riboflavin and has resistance to a proline analog, and to a provide a method for producing the riboflavin by using the Bacillus subtilis microorganism. SOLUTION: The Bacillus subtilis has the resistance to the proline analog, so that proline synthesis is enhanced in cell bodies, osmotic pressure resistance is strengthened, and the riboflavin is produced in a high concentration and a high yield. Therefore, the riboflavin in a large amount is acquired from a culture which is given by culturing the microorganism. COPYRIGHT: (C)2004,JPO&NCIPI | ||||||
| 193 | Galactomannan - oligosaccharides and a method of manufacturing the same, as well as its use | JP2001545566 | 2000-12-12 | JP2003516757A | 2003-05-20 | クリンゲベルグ，ミカエル; クンツ，マルクウォルト; フォーゲル，マンフレッド; ムニル，モハメド; リティッヒ，フランク; ルッドウィッヒ，エヴァ |
| (57)【要約】 本発明は、ガラクトマンナン化合物の加水分解方法、および加水分解物の種々の使用に関する。 | ||||||
| 194 | A new strain of food fermentation Bacillus subtilis group | JP2000574692 | 1999-09-15 | JP2002526113A | 2002-08-20 | ツヴァーレン、マリー、カミーユ; プリドモール、レイモン、デビッド; モレ、ベアト |
| (57)【要約】 本発明は、本質的にイソ吉草酸産生能を失った、豆類を発酵し得るバシラス・サチリス（Ｂａｃｉｌｌｕｓ ｓｕｂｔｉｌｉｓ）の新規菌株に関する。 本発明は特に、イソ吉草酸の産生のための生合成経路に関与する一つないしそれ以上の遺伝子が本質的に非機能的であるＢａｃｉｌｌｕｓ ｎａｔｔｏの新規菌株に関する。 | ||||||
| 195 | SALT-TOLERANT BACILLUS SUBTILIS VAR. CHUNGKOOKJANG STRAIN PRODUCING HIGH MOLECULAR WEIGHT POLY-γ-GLUTAMIC ACID | JP2001401411 | 2001-12-28 | JP2002233391A | 2002-08-20 | SUNG MOON HEE; BAEK DAEHEOUN; LEE SEUNG GOO; SONG JAE JUN; HONG SEUNGPYO; CHOI YOON HO; SHIN SUNYOUNG; HAN JAESUK; ASHIUCHI MAKOTO; SODA KENJI |
| PROBLEM TO BE SOLVED: To provide a method for efficiently producing high molecular weight poly-γ-glutamic acid with a Bacillus strain. SOLUTION: The Bacillus Subtilis var. chungkookjang strain (KCTC0697BP) separated from chungkookjang. The method for producing the poly-γ-glutamic acid with the strain. The poly-γ-glutamic acid produced with the strain and having a molecular weight of >=2,000 kDa. | ||||||
| 196 | Method for oxidizing hydrocarbon having 2-20 carbon atoms by using bacteria and use of the same method | JP2001132716 | 2001-04-27 | JP2002142764A | 2002-05-21 | LENKE HILTRUD; LINJA LAURA; SIEGLEN UTE; KUEHNLE ADOLF; DUDA MARK |
| PROBLEM TO BE SOLVED: To provide an alkanehydroxylase-enzyme system and develop a method for oxidizing a hydrocarbon for making an alcohol by using a microorganism which is resistant to a first oxidized material that is the alcohol thus produced, in an industrially utilizable scale and selectivity. SOLUTION: This method for oxidizing a hydrocarbon having 2-20 carbon atoms by using a bacterium is characterized by oxidizing the hydrocarbon by using a bacterial strain of Rhodococcus rubber KB1, Rhodococcus rubber DSM 7511, Rhodococcus rubber SW 3 or Arthrobacter sp. 11075, their accidentally mutated strain, or their mutated strain obtained by using a genetic engineering method. COPYRIGHT: (C)2002,JPO | ||||||
| 197 | Biological control of fungal infection of the plant | JP52384998 | 1997-11-18 | JP2001503642A | 2001-03-21 | アール． ジメネズ，デスモンド; ディー． ハインズ，シェリー; ジェイ． バンデマーク，ジョージ; ケイ． ベストウィック，リチャード; ゲイル マロン，パメラ; シー． マンカー，デニース |
| (57)【要約】 本発明は、植物病原性真菌および細菌の増殖を阻害するためのBacillus subtilisの独特の株、ならびに植物を真菌および細菌感染から処置または保護する方法に関する。 | ||||||
| 198 | Overcoming of obstacle by dapa aminotransferase in biotin vitamer | JP19819198 | 1998-07-14 | JPH11127887A | 1999-05-18 | PERKINS JOHN B; PERO JANICE G; VAN ARSDELL SCOTT W; YOCUM ROGERS R |
| PROBLEM TO BE SOLVED: To provide a method for bio-synthesizing a biotin vitamer in which the conversion from KAPA to DAPA is not obstructed due to the supply of a high concentration of an amino donor. SOLUTION: This method for overcoming the obstacle by a DAPA aminotransferase in biotin vitamer, which is a method for producing a biotin vitamer, is provided by (a) culturing bacteria having a DAPA aminotransferase utilizing lysine in an environment rich in lysine, a lysine analog or a lysine precursor, or (a) culturing bacteria having a DAPA aminotransferase utilizing lysine and being de-adjusted in regard to the production of lysine, and (b) recovering the biotin vitamer. The bacteria are engineered so as to produce the DAPA aminotransferase utilizing lysine and the DAPA aminotransferase utilizing SAM excessively, and especially the bacteria are further engineered so as to produce the biotin vitamer excessively by a de-adjustment caused by a bio A expression and in addition by an engineering at least one biotin synthesizing process. COPYRIGHT: (C)1999,JPO | ||||||
| 199 | Biotin biosynthesis in bacillus subtills | JP14367294 | 1994-06-24 | JPH07231789A | 1995-09-05 | SUTANREE GURANTO BOUWAA; JIYON BII PAAKINSU; JIYANISU JII PERO; AARU ROJIYAASU YOKAMU |
| PURPOSE: To obtain a new DNA useful for high level production of biotin useful for food additives for human and animals. CONSTITUTION: The DNA includes (A) DNA sequences of genes that encode a biotin biosynthetic enzyme of bacillus subtilis or of a closely related species thereof, (B) DNA sequences encoding the biologically active fragments of the sequence A and (C) a DNA including the DNA sequence selected from practically homologous DNA sequences to the sequence A or the sequence B for example, the sequence of the formula. The DNA is obtained by fixing a single DNA fragment of about 8 kb including all biotin biosynthesis gene from complementation assay using bioA, bioB, bioC, bioD, bioF, and bioH of variant of bacillus coli, and marker rescue and complementation assay using bioA, bioB, and bioF of known bacillus strain biotin variant, and isolating from bacillus subtilis. COPYRIGHT: (C)1995,JPO | ||||||
| 200 | Biomass reaction product | JP21828593 | 1993-09-02 | JPH06189778A | 1994-07-12 | JIEIMUZU EI BURAIAREI; KOREIRU ERU BURAIAREI; REIMONDO EFU DETSUKAA; JIYOOJI EMU GOYATSUKU |
| PURPOSE: To enhance the metal uptake property of a biomass reaction product. CONSTITUTION: This biomass reaction product is produced e.g. from Bacillus subtilis by treating Bacillus subtilis cell with a caustic solution. It give s a relatively solid material by washing and drying, has essentially high metal uptake property compared with the metal uptake property of Bacillus subtilis before treatment, takes granular form in water and exhibits metal uptake property when brought into contact with an aqueous solution containing metal cations. It can be produced by the caustic treatment of the cell at a temperature between about 50°C and 100°C in an aqueous solution of NaOH or KOH. COPYRIGHT: (C)1994,JPO | ||||||
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