| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 141 | Systems and methods for processing cells | US14547966 | 2014-11-19 | US08967513B1 | 2015-03-03 | Rouzbeh R. Taghizadeh; John Meade |
| The present invention efficiently and cost-effectively extracts and collects cells from a tissue. The inventors have discovered that the tissue can be effectively fragmented and the resulting cells can be purified using a system or kit with multiple components. An advantage of the present invention is that tissue processing takes place in a closed system such that sterility can be maintained throughout the process, even if certain components are removed during processing, for example through the use of valves, clamps, and heal seals. Furthermore, any or all of the steps can be automated or manually accomplished, according to the specific needs of the application or the user. | ||||||
| 142 | Systems and methods for processing cells | US13933034 | 2013-07-01 | US08893995B2 | 2014-11-25 | Rouzbeh R. Taghizadeh; John Meade |
| The present invention efficiently and cost-effectively extracts and collects cells from a tissue. The inventors have discovered that the tissue can be effectively fragmented and the resulting cells can be purified using a system or kit with multiple components. An advantage of the present invention is that tissue processing takes place in a closed system such that sterility can be maintained throughout the process, even if certain components are removed during processing, for example through the use of valves, clamps, and heat seals. Furthermore, any or all of the steps can be automated or manually accomplished, according to the specific needs of the application or the user. | ||||||
| 143 | Postpartum-derived cells for use in treatment of disease of the heart and circulatory system | US10877445 | 2004-06-25 | US08703121B2 | 2014-04-22 | Ian Ross Harris; Alexander M. Harmon; Anthony J. Kihm; Anna Gosiewska |
| Cells derived from postpartum tissue and methods for their use in treatment of diseases of the heart or circulatory system are disclosed. Cells may be used in either differentiated or undifferentiated forms, in homogenous cultures, or as populations with other cells, and in conjunction with other bioactive factors. | ||||||
| 144 | SYSTEMS AND METHODS FOR PROCESSING CELLS | US13933034 | 2013-07-01 | US20130295673A1 | 2013-11-07 | Rouzbeh R. Taghizadeh; John Meade |
| The present invention efficiently and cost-effectively extracts and collects cells from a tissue. The inventors have discovered that the tissue can be effectively fragmented and the resulting cells can be purified using a system or kit with multiple components. An advantage of the present invention is that tissue processing takes place in a closed system such that sterility can be maintained throughout the process, even if certain components are removed during processing, for example through the use of valves, clamps, and heat seals. Furthermore, any or all of the steps can be automated or manually accomplished, according to the specific needs of the application or the user. | ||||||
| 145 | HAIR FOLLICLE MESENCHYMAL STEM CELLS AND USE THEREOF | US13661782 | 2012-10-26 | US20130115198A1 | 2013-05-09 | ROLF HOFFMANN; KEVIN J. MCELWEE |
| The present invention relates to a method for isolating hair follicle mesenchymal stem cells and to the use thereof for therapy and prophylaxis as well as for cosmetic treatments. | ||||||
| 146 | REGENERATION AND REPAIR OF NEURAL TISSUE USING POSTPARTUM-DERIVED CELLS | US13605716 | 2012-09-06 | US20130022585A1 | 2013-01-24 | DARIN J. MESSINA; Sanjay Mistry; Alexander M. Harmon; Ian Ross Harris; Anthony J. Kihm; Agnieszka Seyda; Chin-Feng Yi; Anna Gosiewska |
| Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed. | ||||||
| 147 | METHODS AND APPARATUS FOR ENHANCED RECOVERY OF CELLS AND OF CELL-ENRICHED MATRIX FROM TISSUE SAMPLES | US13329143 | 2011-12-16 | US20120195863A1 | 2012-08-02 | Eckhard U. Alt; Michael E. Coleman; Ron Stubbers |
| This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed. | ||||||
| 148 | Method for isolation of inner cell mass and method of preparation of embryonic stem cell lines using inner cell mass isolated by the same | US12459869 | 2009-07-10 | US08093051B2 | 2012-01-10 | Chang Hyun Kim |
| A method for isolation of an inner cell mass and a method for preparation of embryonic stem cell lines using the inner cell mass isolated by the same. A blastocyst being free from a zona pellucida removed therefrom is placed on a feeder cell, and a micro cover glass is put on the blastocyst to apply pressure caused by a weight of the micro cover glass, to the blastocyst for a desired time, so that the inner cell mass may be obtained with considerably improved yield compared to conventional methods, and therefore, an embryonic stem cell line may be efficiently established and proliferated. | ||||||
| 149 | POSTPARTUM CELLS DERIVED FROM UMBILICAL CORD TISSUE, AND METHODS OF MAKING AND USING THE SAME | US12389305 | 2009-02-19 | US20100210013A1 | 2010-08-19 | Sanjay Mistry; Anthony J. Kihm; Ian Ross Harris; Alexander M. Harmon; Darin J. Messina; Agnieszka Seyda; Chin-Feng Yi; Anna Gosiewska |
| Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described. | ||||||
| 150 | Soft tissue repair and regeneration using postpartum-derived cells | US10877009 | 2004-06-25 | US07560276B2 | 2009-07-14 | Alexander M. Harmon; Ian Ross Harris; Anthony J. Kihm; Sanjay Mistry; Darin J. Messina; Agnieszka Seyda; Chin-Feng Yi; Anna Gosiewska |
| Cells derived from postpartum tissue having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue. | ||||||
| 151 | Regeneration and repair of neural tissue using postpartum-derived cells | US10877269 | 2004-06-25 | US07524489B2 | 2009-04-28 | Darin J. Messina; Sanjay Mistry; Alexander M. Harmon; Ian Ross Harris; Anthony J. Kihm; Agnieszka Seyda; Chin-Feng Yi |
| Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed. | ||||||
| 152 | Postpartum cells isolated from umbilical cord tissue, and methods of making and using the same | US10877012 | 2004-06-25 | US07510873B2 | 2009-03-31 | Sanjay Mistry; Anthony J. Kihm; Ian Ross Harris; Alexander M. Harmon; Darin J. Messina; Chin-Feng Yi; Anna Gosiewska |
| Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described. | ||||||
| 153 | Treatment of retinitis pigmentosa with human umbilical cord cells | US10877541 | 2004-06-25 | US07413734B2 | 2008-08-19 | Sanjay Mistry; Darin J. Messina; Ian Ross Harris; Alexander M. Harmon; Agnieszka Seyda; Chin-Feng Yi; Anna Gosiewska |
| Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed. | ||||||
| 154 | Soft tissue repair and regeneration using postpartum-derived cells and cell products | US11316104 | 2005-12-22 | US20060153816A1 | 2006-07-13 | Laura Brown; Alexander Harmon; Anna Gosiewska |
| Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue. | ||||||
| 155 | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same | US10877012 | 2004-06-25 | US20050054098A1 | 2005-03-10 | Sanjay Mistry; Anthony Kihm; Ian Harris; Alexander Harmon; Darin Messina; Agnieszka Seyda; Chin-Feng Yi; Anna Gosiewska |
| Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described. | ||||||
| 156 | Repair and regeneration of ocular tissue using postpartum-derived cells | US10877541 | 2004-06-25 | US20050037491A1 | 2005-02-17 | Sanjay Mistry; Darin Messina; Ian Harris; Alexander Harmon; Anthony Kihm; Agnieszka Seyda; Chin-Feng Yi; Anna Gosiewska |
| Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed. | ||||||
| 157 | Adhesive signature-based methods for the isolation of stem cells and cells derived therefrom | US14128547 | 2012-06-21 | US10106780B2 | 2018-10-23 | Ankur Singh; Shalu Suri; Todd Christopher McDevitt; Hang Lu; Andres Jose Garcia |
| The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces. | ||||||
| 158 | METHOD FOR CULTURING PRIMARY CELLS | US15444588 | 2017-02-28 | US20180023055A1 | 2018-01-25 | Norikatsu MIYOSHI; Shiki FUJINO; Masayuki OHUE; Masayoshi YASUI |
| Method for producing a primary culture of cancer cells, comprising: (a) fragmenting cancer tissues derived from a living body and removing impurities from the fragmented cancer tissues, (b) subjecting the tissue masses obtained in (a) to suspension culture, and (c) subjecting the culture obtained in (b) to adherent culture. | ||||||
| 159 | SYSTEMS FOR DISSOCIATION OF BIOLOGICAL TISSUES | US15532854 | 2015-12-04 | US20170355950A1 | 2017-12-14 | Yitshak ZOHAR; Linda L. RESTIFO; Linan JIANG |
| Provided herein is technology relating to processing biological samples and particularly, but not exclusively, to systems and apparatuses for dissociating biological tissues into viable cells. | ||||||
| 160 | STEM CELLS & DECELLULARIZED TISSUE MATRIX FROM CORD TISSUE | US15613264 | 2017-06-05 | US20170327792A1 | 2017-11-16 | Raymond MOUZANNAR |
| Methods and products obtained from the method for isolating and culturing mixed populations of stem cells, making decellularized tissue matrix, making decellularized tissue matrix infused with said mixed populations of stem cells, and methods of stem cell therapy are provided. | ||||||
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