| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 81 | Pyridinee2*3*66triones*their manufacture and their use as silver dyeebleaching catalyst | JP3763780 | 1980-03-26 | JPS55130959A | 1980-10-11 | UIRIAMU EDOWAADO RONGU |
| 82 | 11benzyll1*2*5*66tetrahydropyridinee33carboxylic acid derivative*its manufacture and pharmacological composition containing it for therapy of thrombosis or latent blooddvessel disease | JP14876479 | 1979-11-16 | JPS5572165A | 1980-05-30 | RARUFU HAUE; SUCHIYUAATO DONETSUTO MIRUZU |
| 83 | Production of hydronaphthalene derivative | JP9576078 | 1978-08-04 | JPS5436240A | 1979-03-16 | FUREDERITSUKU PEETAA HOOKU; MAIKERU EDOWAADO KONDON; JIYOISU AN REIDO |
| 84 | JPS5128715B2 - | JP4132474 | 1974-04-11 | JPS5128715B2 | 1976-08-20 | |
| 85 | Purosutaguranjinruijikagobutsuno seizohoho | JP14118374 | 1974-12-10 | JPS5168547A | 1976-06-14 | HAYASHI MASAKI; KOORI SEIJI; OKADA YOSHIKATSU; IIJIMA YOSHITSUGU |
| 86 | MÉTODO PARA LA DETECCIÓN ELECTROQUÍMICA DE SECUENCIAS DE ÁCIDOS NUCLÉICOS | PCT/ES2008/000364 | 2008-05-23 | WO2008145785A1 | 2008-12-04 | LORENZO ABAD, Encarnación; PARIENTE ALONSO, Felix; REVENGA PARRA, Monica; GARCIA MENDIOLA, Tania |
Es objeto de la presente invención un nuevo compuesto derivado de rutenio, de fórmula (I), denominado complejo de pentamin rutenio [3-(2-fenantren-9-il-vinil)piridina], así como su empleo como indicador electroquímico de hibridación en un método para la detección de hibridación entre secuencias de ácidos nucleicos, para la cuantificación de dichas secuencias, así como la detección de la presencia de una base desapareada y su posición dentro de una secuencia de ácido nucleico. |
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| 87 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | PCT/US2006/032877 | 2006-08-22 | WO2007024922A1 | 2007-03-01 | GAO, Wenqi; WAN, Yongqin; JIANG, Jiqing; FAN, Yi; GRAY, Nathanael, S.; PAN, Shifeng |
The present invention relates to immunosuppressants, processes for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, particularly diseases associated with EDG receptor mediated signal transduction. This application relates to compounds selected from Formula (Ia), (Ib), (Ic) and (Id). |
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| 88 | MONO-ACYLATED O-PHENYLENDIAMINES DERIVATIVES AND THEIR USE AGAINST CANCER | PCT/EP2004001044 | 2004-02-05 | WO2004069803A3 | 2004-11-18 | FERTIG GEORG; HERTING FRANK; KUBBIES MANFRED; LIMBERG ANJA; REIFF ULRIKE; WEIDNER MICHAEL |
| Objects of the present invention are new mono-acylated o-phenylendiamines derivatives of formula (A) wherein Ar is thiophen-2,5-diyl, pyridine-2,5-diyl, pyridine-5,2-diyl, pyridine-2,6-diyl, pyridine-2,4-diyl or 1,4-phenylene, R<1>, R<2> independently from each other represent hydrogen, C1-12-alkyl, C2-12-alkenyl, C2-12-alkynyl, C3-12-cycloalkyl, the alkyl, alkenyl, alkynyl and cycloalkyl groups being optionally mono or multiple substituted by hydroxy, halogen, C3-12-cycloalkyl, alkoxy, alkylsulfanyl, acyloxy, alkoxycarbonyl, acyl, C1-6-alkyl-NH-C(O)-, C1-6-alkyl-C(O)NH- or -NR<3>R<4>, or alternatively R<1> is hydrogen, and R<2> is hydroxyl, alkoxy, C2-C12-alkenyloxy or phenoxy, which phenoxy group is optionally substituted with methyl, methoxy, halogen, nitro, cyano, trifluoromethyl, ethenyl or -C(O)-O-CH3, provided that if R<2> is hydroxy, Ar is not thiophen-2,5-diyl; and R<3> and R<4> independently from each other represent hydrogen or C1-6-alkyl, or wherein R<3> and R<4> together with the nitrogen-atom to which they are attached form a ring, which ring is monosubstituted by oxo and which ring may contain a further heteroatom, and pharmaceutically acceptable salts thereof, as well as processes for the manufacturing of these compounds, pharmaceutical compositions containing such compounds and their use in the manufacture of drugs for the treatment of diseases such as cancer. | ||||||
| 89 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDINES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PCT/US0143280 | 2001-11-20 | WO0242272A8 | 2003-10-23 | SOUTH MICHAEL S; CASE BRENDA; GARLAND DANNY J; HAYES MICHAEL J; HUANG HORNG-CHIH; HUANG WEI; JONES DARIN E; NEUMANN WILLIAM L; PARLOW JOHN J; REITZ DAVID B; RUEPPEL MELVIN L; WEBBER RONALD K |
| The present invention relates to compounds, and prodrugs thereof, composition and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade. | ||||||
| 90 | HYDROXYPYRIDONE METHIDE AZO DYES | PCT/EP2001/006408 | 2001-06-06 | WO01094314A1 | 2001-12-13 | |
| The invention relates to hydroxypyridone methide azo dyes corresponding to the formula (I) and to their tautomer forms. In said formula, the substituents X<1> to X<4>, R<1> and R<2> are defined as per the description. Said dyes are particularly suitable for dyeing and printing hydrophobic, synthetic-fibre materials, or mixtures thereof and natural-fibre materials. | ||||||
| 91 | NEW OXIME SULFONATES AND THE USE THEREOF AS LATENT SULFONIC ACIDS | PCT/EP1998/003750 | 1998-06-19 | WO99001429A1 | 1999-01-14 | |
| New oximsulfonate compounds of formulae (I) or (II), wherein m is 0 or 1; x is 1 or 2; R1 is, for example phenyl, which is unsubstituted or substituted or R1 is a heteroaryl radical that is unsubstituted or substituted, or, if m is 0, R1 additionally is C2-C6alkoxycarbonyl, phenoxycarbonyl or CN; R'1 is for example C2-C12alkylene, phenylene; R2 has for example one of the meanings of R1; n is 1 or 2; R3 is for example C1-C18alkyl, R'3 when x is 1, has one of the meanings given for R3, or R'3 in formula (IV) and when x is 2 in formula (I), is for example C2-C12 alkylene, phenylene; R4 and R5 are independently of each other for example hydrogen, halogen, C1-C6alkyl; R6 is for example hydrogen, phenyl; R7 and R8 are independently of each other for example hydrogen or C1-C12alkyl; R9 is for example C1-C12alkyl; A is S, O, NR6, or a group of formula (A1), (A2), (A3) or (A4); R10 and R11 independently of each other have one of the meanings given for R4; R12, R13, R14 and R15 independently of one another are for example hydrogen, C1-C4alkyl; Z is CR11 or N; Z1 is -CH2-, S, O or NR6, are useful as latent sulfonic acids, especially in photoresist applications. | ||||||
| 92 | PYRIDINIUM INTERMEDIATES AND THE PROCESS FOR PREPARING THE SAME | PCT/US1993007521 | 1993-08-11 | WO1994004502A1 | 1994-03-03 | ABBOTT LABORATORIES; WANG, Xiu, C.; KALARITIS, Panos; CHANG, Michelle, L. |
| A process for the preparation of halobenzoic acids, comprising the step of reacting a halonitrobenzene with a pyridinium salt to form an intermediate of formula (I), wherein R is selected from the group consisting of hydrogen, alkyl, aryl, alkenyl, alkynyl, -CN, -COOR' and -COR' where R' is alkyl or aryl; X is chloro or fluoro; Y is hydrogen, chloro or fluoro; and Z is chloro, bromo or iodo. | ||||||
| 93 | PSEUDOMONAS STRAINS AND THEIR METABOLITES TO CONTROL PLANT DISEASES | EP21791575.0 | 2021-10-04 | EP4225894A1 | 2023-08-16 | YANG, Ching-hong; HUANG, Jian |
| 94 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-AMINO-3-HYDROXYPYRIDINE, AND HAIR DYEING PROCESS USING THESE DYES AND PRECURSORS | EP08862628.8 | 2008-12-09 | EP2231607B1 | 2013-07-03 | LEDUC, Madeleine; SABELLE, Stéphane; METAIS, Eric; RONDOT, Christophe |
| 95 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-AMINO-3-HYDROXYPYRIDINE, AND HAIR DYEING PROCESS USING THESE DYES AND PRECURSORS | EP08862628.8 | 2008-12-09 | EP2231607A1 | 2010-09-29 | LEDUC, Madeleine; SABELLE, Stéphane; METAIS, Eric; RONDOT, Christophe |
| The invention relates to the dyeing of keratin fibres using azomethine direct dyes or reduced precursors of azomethine direct dyes of formula (I) and (II) obtained from 2 -amino- 3-hydroxypyridine. The invention relates to a dye composition comprising at least one azomethine direct dye or a reduced precursor of an azomethine direct dye, to a process for dyeing keratin fibres, using the said composition, and to their uses in the dyeing of keratin fibres. This composition allows a particularly stable and fast coloration to be obtained. | ||||||
| 96 | NEW MONO-ACYLATED O-PHENYLENDIAMINES DERIVATIVES | EP04708323.3 | 2004-02-05 | EP1592667A2 | 2005-11-09 | FERTIG, Georg; HERTING, Frank; KUBBIES, Manfred; LIMBERG, Anja; REIFF, Ulrike; WEIDNER, Michael |
| Objects of the present invention are new mono-acylated o-phenylendiamines derivatives of formula (A) wherein Ar is thiophen-2,5-diyl, pyridine-2,5-diyl, pyridine-5,2-diyl, pyridine-2,6-diyl, pyridine-2,4-diyl or 1,4-phenylene, R1, R2 independently from each other represent hydrogen, C1-12-alkyl, C2-12-alkenyl, C2-12-alkynyl, C3-12-cycloalkyl, the alkyl, alkenyl, alkynyl and cycloalkyl groups being optionally mono or multiple substituted by hydroxy, halogen, C3-12-cycloalkyl, alkoxy, alkylsulfanyl, acyloxy, alkoxycarbonyl, acyl, C1-6-alkyl-NH-C(O)-, C1-6-alkyl-C(O)NH- or -NR3R4, or alternatively R1 is hydrogen, and R2 is hydroxyl, alkoxy, C2-C12-alkenyloxy or phenoxy, which phenoxy group is optionally substituted with methyl, methoxy, halogen, nitro, cyano, trifluoromethyl, ethenyl or -C(O)-O-CH3, provided that if R2 is hydroxy, Ar is not thiophen-2,5-diyl; and R3 and R4 independently from each other represent hydrogen or C1-6-alkyl, or wherein R3 and R4 together with the nitrogen-atom to which they are attached form a ring, which ring is monosubstituted by oxo and which ring may contain a further heteroatom, and pharmaceutically acceptable salts thereof, as well as processes for the manufacturing of these compounds, pharmaceutical compositions containing such compounds and their use in the manufacture of drugs for the treatment of diseases such as cancer. | ||||||
| 97 | Pyridonfarbstoffe und ein Verfahren zu ihrer thermischen Übertragung | EP91116395.4 | 1991-09-26 | EP0480252B1 | 1995-07-26 | Bach, Volker, Dr.; Sens, Ruediger, Dr.; Etzbach, Karl-Heinz, Dr. |
| 98 | Pyridonfarbstoffe und ein Verfahren zu ihrer thermischen Übertragung | EP91116395.4 | 1991-09-26 | EP0480252A1 | 1992-04-15 | Bach, Volker, Dr.; Sens, Ruediger, Dr.; Etzbach, Karl-Heinz, Dr. |
Pyridonfarbstoffe der Formel
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| 99 | Fungicides | EP91117381.3 | 1988-01-14 | EP0472224A1 | 1992-02-26 | Clough, John Martin; Godfrey, Christopher Richard Ayles; De Fraine, Paul John; Hutchings, Michael Gordon; Anthony, Vivienne Margaret |
Fungicidal compounds of the formula (I):
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| 100 | Fungicides | EP88300280.0 | 1988-01-14 | EP0278595A2 | 1988-08-17 | Clough, John Martin; Godfrey, Christopher Richard Ayles; De Fraine, Paul John; Hutchings, Michael Gordon; Anthony, Vivienne Margaret |
Fungicidal compounds of the formula (I) :
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