序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
41 METHOD OF PRODUCING DIMETHYL SULFITE PCT/EP0000771 2000-02-01 WO0046218A3 2000-12-07 HALBRITTER KLAUS; STERZEL HANS-JOSEF; TRAGUT CHRISTIAN; FREUDENTHALER EVA
The invention relates to a method of producing dimethyl sulfite by reacting a cyclic alkylene sulfite having at least 2 carbon atoms with methanol, optionally in the presence of a catalyst. The inventive method is carried out in a continuous manner in a column.
42 METHOD OF PRODUCING DIMETHYL SULFITE PCT/EP2000/000771 2000-02-01 WO00046218A2 2000-08-10
The invention relates to a method of producing dimethyl sulfite by reacting a cyclic alkylene sulfite having at least 2 carbon atoms with methanol, optionally in the presence of a catalyst. The inventive method is carried out in a continuous manner in a column.
43 SULPHITED FATS WITH A REDUCED FREE-BISULPHITE CONTENT PCT/EP1993003274 1993-11-22 WO1994012471A1 1994-06-09 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention concerns the production of sulphited fats with a reduced free-bisulphite content by blowing unsaturated fats using prior art methods, sulphiting with sodium metabisulphite and finally binding unreacted hydrogen sulfite as sulphosuccinic acid esters by treating with maleic acid esters and, if necessary, bases. The products are suitable for use in the production of leather-oiling and leather-waterproofing agents.
44 VERBINDUNGEN MIT (METH)ACRYLAT-RESTEN UND SULFONAT- ODER SULFATGRUPPEN, POLYMERE UND KONDENSATE DARAUS SOWIE VERWENDUNG DER POLYMERE UND KONDENSATE EP12723194 2012-05-24 EP2714653B1 2017-05-03 WOLTER HERBERT; SEYFRIED MONA; NIQUE SOMCHITH
45 NOVEL NITROPHENYL MUSTARD AND NITROPHENYLAZIRIDINE ALCOHOLS AND THEIR CORRESPONDING PHOSPHATES AND THEIR USE AS TARGETED CYTOTOXIC AGENTS EP04817434 2004-10-29 EP1680394A4 2006-10-11 DENNY WILLIAM ALEXANDER; ATWELL GRAHAM JOHN; YANG SHANGJIN; WILSON WILLIAM ROBERT; PATTERSON ADAM VORN; HELSBY NUALA ANN
46 VERFAHREN ZUR HERSTELLUNG VON DIMETHYLSULFIT EP00910634.5 2000-02-01 EP1149088B1 2003-04-23 HALBRITTER, Klaus; STERZEL, Hans-Josef; TRAGUT, Christian; FREUDENTHALER, Eva
The invention relates to a method of producing dimethyl sulfite by reacting a cyclic alkylene sulfite having at least 2 carbon atoms with methanol, optionally in the presence of a catalyst. The inventive method is carried out in a continuous manner in a column.
47 VERFAHREN ZUR HERSTELLUNG VON DIMETHYLSULFIT EP00910634.5 2000-02-01 EP1149088A2 2001-10-31 HALBRITTER, Klaus; STERZEL, Hans-Josef; TRAGUT, Christian; FREUDENTHALER, Eva
The invention relates to a method of producing dimethyl sulfite by reacting a cyclic alkylene sulfite having at least 2 carbon atoms with methanol, optionally in the presence of a catalyst. The inventive method is carried out in a continuous manner in a column.
48 SYNTHESIS OF ARYLOXYPROPANOLAMINES AND ARYLETHANOLAMINES. EP87900373 1986-11-14 EP0248879A4 1990-02-26 PATIL GHANSHYAM; MAI KHUONG H X; MATIER WILLIAM L
A process for preparing a racemic or chiral aryloxypropanolamine (1) or arylethanolamine (2) of the formula (1) or (2) wherein Ar is aryl, substituted aryl, heteroaryl, or aralkyl and R is alkyl, substituted alkyl, aralkyl or WB wherein W is a straight or branched chain alkylene of from 1 to about 6 carbon atoms and wherein B is -NR2COR3, -NR2CONR3R4, -NR2SO2R3, -NR2SO2NR3R4, or -NR2COOR5, where R2, R3, R4, and R5 may be the same or different and may be hydrogen, alkyl, alkoxyalkyl, alkoxyaryl, cycloalkyl, alkenyl, alkynil, aryl, heteroaryl, or aralkyl, except that R3 and R5 are not hydrogen when B is -NR2SO2R3 or -NR2COOR5, or R3 and R4 may together with N form a 5- to 7-membered heterocyclic group. The process can be used to prepare beta-blocking agents, useful in the treatment of cardiac conditions.
49 Process for the preparation of 4,4'-dinitrostilbene-disulfonic acid EP86106873 1986-05-21 EP0203506B1 1988-08-24 SKIPKA, GUIDO, DR.; DURHOLZ, FRIEDRICH, DR.
50 Urethanes containing perfluoroalkyl groups, epichlorhydrine groups, and dialcohol rests, process for their preparation and their use EP86115437 1986-11-07 EP0222334A3 1988-08-03 WEHOWSKY, FRANK, DR.; KLEBER, ROLF, DR.; JAECKEL, LOTHAR
51 Quinolones having antihypertensive activity. EP86304390 1986-06-09 EP0206616A2 1986-12-30 DAVIES ROY VICTOR; FRASER JAMES; NICHOL KENNETH JOHN
Quinolines with antihypertensive activity have the general formula I, …… wherein X is the residue of an optionally substituted benzene ring; R is lower alkyl; R3 is hydrogen or lower alkyl; R1 and R2, which may be the same or different, are hydrogen, lower alkyl, or, together with the nitrogen atom to which they are attached, form a 5 to 7 membered saturated heterocyclic ring optionally containing an additional hetero atom selected from nitrogen, oxygen and sulphur and optionally substituted by 1 or more lower alkyl groups; and the dotted line between positions 2 and 3 of the quinolone nucleus represents an optional bond. The compounds are useful as antihypertensive agents. They are also indicated for use in treating heart failure and ischaemic heart disease. …With the exception of the three compounds 1-methyl-4-oxo-1,4-dihydroquinoline-3-sulphonamide, 1,N-dimethyl-4-oxo-1,4-dihydroquinoline-3-sulphonamide and 6,7-dimethoxyl-methyl-4-oxo-1,4-dihydroquinoline-3-sulphonamide, the quinolones of formula I are novel. …Pharmaceutical compositions containing the compounds of formula I are described. Processes for preparing the novel quinolones are also described.
52 Verfahren zur Herstellung von 1,8-verbrückten 4-Chinolon-3-carbonsäuren. EP86107908 1986-06-10 EP0206101A1 1986-12-30 GROHE KLAUS DR; SCHRIEWER MICHAEL DR
Die Erfindung betrifft ein Verfahren zur Herstellung von 1,8-verbrückten 4-Chinolon-3-carbonsäuren, deren Zwischenprodukte sowie ihre Verwendung als Arzneimittel, insbesondere als antibakterielle Mittel in der Human- und Veterinärmedizin.
53 Process for the preparation of p-tolvidine-2-sulfonic acid EP85100112 1985-01-07 EP0149460B1 1986-12-30 BLANK, HEINZ ULRICH, DR.; EMDE, HERBERT, DR.; SCHIMPF, ROLF, DR.
54 PROCESS FOR THE PREPARATION OF 2-CHLOROSULFONYL-4-(N-SUBSTITUTED SULFAMYL)-CHLOROBENZENE COMPOUNDS EP83304162 1983-07-18 EP0104721B1 1986-12-30 NAKAHASHI, KAZUAKI; MIYAMURA, SOUJI; TAKEUCHI, TADASHI
55 NOUVEAUX DERIVES DE LA BENZAMIDE. EP79900115 1979-08-13 EP0009487A1 1980-04-16 PURCELL WILLIAM PAUL; PARISH JR HARLIE A
Nouveaux derives de la benzamide therapeutiquement actifs, de formule generale (FORMULE) dans laquelle R1 et R2 sont independamment l'un de l'autre de l'hydrogene ou un groupe alkyle inferieur, R3 est un groupe phenyle ou alkyle inferieur ou alkenyle inferieur, R4 est un halogene ou un groupe trifluoromethyle ou nitro, R5 est un groupe sulfamoyle ou carboxyle ou carboxalkyle, et les sels de potassium de ces derives. Ces composes sont des diuretiques et hypotenseurs et ils abaissent les fonctions angiotensine et renine, avec action prolongee.
56 PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM EP79301600 1979-08-07 EP0008226A3 1980-03-05 UEDA, IKUO; KITAURA, YOSHIHIKO; KONISHI, NOBUKIYO
57 5-クロロ-1,1,2,2,3,3,4,4-オクタフルオロペンタンの製造方法及び1-クロロ-2,3,3,4,4,5,5-ヘプタフルオロペンテンの製造方法 PCT/JP2018/045931 2018-12-13 WO2019124220A1 2019-06-27 市野川 真理; 藤森 厚史; 岩瀬 卓也; 岡本 秀一

複雑な後処理工程が不要で、高選択率で5-クロロ-1,1,2,2,3,3,4,4-オクタフルオロペンタンを製造することのできる効率的な製造方法の提供。N,N-ジメチルホルムアミド、ジメチルアセトアミド、ピリジン及びテトラメチル尿素からなる群より選ばれる少なくとも1種の含窒素有機化合物の存在下、2,2,3,3,4,4,5,5-オクタフルオロペンタノールと塩化チオニルを反応させて2,2,3,3,4,4,5,5-オクタフルオロペンタンスルホン酸クロライドを製造する第1の工程と、前記2,2,3,3,4,4,5,5-オクタフルオロペンタンスルホン酸クロライドを熱分解することにより、5-クロロ-1,1,2,2,3,3,4,4-オクタフルオロペンタンを得る第2の工程とを有する5-クロロ-1,1,2,2,3,3,4,4-オクタフルオロペンタンの製造方法。

58 TRIFUNCTIONAL ADDITIVES FOR ELECTROLYTE COMPOSITION FOR LITHIUM BATTERIES PCT/EP2018/051107 2018-01-17 WO2018134251A1 2018-07-26 YOSHIDA, Kazuki; FUKUZUMI, Takeo; KIM, Jinbum; SAWADA, Eri; SCHULZ-DOBRICK, Martin

An electrolyte composition containing (i) at least one aprotic organic solvent; (ii) at least one conducting salt; (iii) at least one compound of formula (I); and (iv) optionally one or more additives.

59 NEW ANTICANCER COMPOUNDS PCT/EP2008065985 2008-11-21 WO2009065926A3 2009-07-30 SPARATORE ANNA; DEL SOLDATO PIERO; SANTUS GIANCARLO
The present invention relates to new polysulf urated compounds containing 2 or more sulphur atoms belonging to the class of organic thiosulf onates, or dithiole-thione derivatives cyclic or linear, or trithiocarbonates for the use alone or in combination with other anticancer treatments for the treatment and/or prevention of cancer and inflammatory diseases.
60 POLYMERIZABLE SULFONATE IONIC LIQUIDS AND LIQUID POLYMERS THEREFROM AND METHODS OF MAKING SAME PCT/US2007/018335 2007-08-17 WO2008021533A3 2008-02-21 RICKS-LASKOSKI, Holly, L.; SNOW, Arthur, W.

Disclosed is a new ionic liquid monomer salt and methods of is synthesis and polymerization. The ionic liquid monomer salt is prepared by mixing equimolar amounts of an amine, such as tris[2-(2-methoxyethoxy)-ethyl]amine and an acid functionalized polymerizable monomer, such as 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS),- which is stirred at ambient temperature until salt formation is complete. Also disclosed is a new ionic liquid polymer salts and method for making the same. The synthesis of AMPS- ammonium salt polymer is accomplished by adding 2,2'-azobisisobutyronitrile (AIBN) to the ionic liquid monomer salt and heating the homogeneous melt at 70°C for 18 hr.

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