子分类：
- C07C235/02：·带有连接在非环碳原子上的羧酰胺基的碳原子和连接在同一碳架上的单键氧原子
- C07C235/40：·带有连接在除六元芳环以外的环的碳原子上的羧酰胺基的碳原子和连在同一碳架上的单键氧原子
- C07C235/42：·带有连接在六元芳环碳原子上的羧酰胺的碳原子和连在同一碳架上的单键氧原子
- C07C235/68：·至少1个羧酰胺基的氮原子连接在非环碳原子和至少有一个邻位氢原子被取代的六元芳环碳原子上
- C07C235/70：·带有连接在同一碳架上的羧酰胺基的碳原子和双键氧原子
- C07C235/86：·含有至少1个羧酰胺基的氮原子季铵化
- C07C235/88：·含有至少1个羧酰胺基的氮原子进一步被酰化
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 361 | Process for purifying oxalic acid diamide | US129843 | 1987-12-08 | US5047587A | 1991-09-10 | Loreno Lorenzoni; Giuseppe Messina; Vittorio Bruzzi |
| A process is disclosed for the purification of the diamide of oxalic acid obtained by means a process wherein copper catalysts are used, by means of the washing with aqueous solutions of an ammonium salt of an organic or inorganic acid, operating at a pH value comprised within the range of from 2 to 8, and at a temperature comprised within the range of from 40.degree. to 150.degree. C. | ||||||
| 362 | Chemical compounds | US298752 | 1989-01-19 | US4999377A | 1991-03-12 | Peter W. R. Caulkett; Michael J. Cooper; Murdoch Eakin; Geraint Jones |
| 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide compounds are disclosed as useful in the treatment of obesity and related conditions. Processes for their preparation are described, as are novel intermediates and pharmaceutical compositions containing them. | ||||||
| 363 | Polyhydroxylated and highly fluorinated compounds, their preparation and their use as surfactants | US78626 | 1987-07-28 | US4985550A | 1991-01-15 | Brigitte Charpiot; Jacques Greiner; Maurice Le Blanc; Alexandre Manfredi; Jean Riess; Leila Zarif |
| Compounds having a polyhydroxylated hydrophilic moiety, a highly fluorinated moiety and a functional junction group linking said moieties together, wherein said hydrophilic moiety is derived from a polyol or an aminopolyol, and wherein said highly fluorinated moiety consists of a fluorocarbon group wherein at lest 50% of the atoms bonded to the carbon skeleton are fluorine atoms, the other atoms bonded to the carbon skeleton being hydrogen, chlorine or bromine atoms, said highly fluorinated moiety containing at least 4 fluorine atoms; as well as the internal ethers and ketals thereof; process for their preparation; and a compositions containing said compounds as surfactants, together with non polar compounds, for use as gas carriers. | ||||||
| 364 | 1-phenoxy-3-amino-2-propanols use thereof | US125308 | 1987-11-25 | US4948812A | 1990-08-14 | Herbert Koppe; Franz Esser; Walter Kobinge; Christian Lillie |
| Compounds of formula ##STR1## (the substituents R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are explained in the specification) may be prepared by conventional methods.Owing to their favorable activity profile the compounds may advantageously be used to treat certain heart and circulatory disorders. | ||||||
| 365 | 4-Vinyl-2-methylene butanedioic acid compounds | US499052 | 1983-05-27 | US4438246A | 1984-03-20 | Rodney D. Bush |
| 4-Vinyl-2-methylenebutanedioic acid and its esters, as well as amide and nitrile analogs of these compounds, are diclosed. These compounds are capable of undergoing a rapid free radical cyclopolymerization reaction. The compounds, themselves, may be used as film-formers (for example, in paints or plastics) or may be used as groups pendant from a backbone, especially a low molecular weight backbone, to form other, more complex film-forming polymer precursor materials. | ||||||
| 366 | Process for the production of oxamide | US3714251D | 1970-04-08 | US3714251A | 1973-01-30 | WEIGERT W; LUSSLING T; THEISSEN F |
| OXAMIDE IS PRODUCED BY THE HYDROLYSIS OF CYANOGEN WITH WATER IN THE PRESENCE OF HYDROGEN HALIDE IN AN ORGANIC SOLVENT SUCH AS SULFONES, KETONES, CYCLIC AND ACYCLIC ETHERS.
|
||||||
| 367 | Production of adiponitrile | US3671568D | 1970-04-29 | US3671568A | 1972-06-20 | ONSAGER OLAV TORGEIR |
| D R A W I N G
|
||||||
| 368 | Process for the production of oxamide | US3600441D | 1969-02-27 | US3600441A | 1971-08-17 | LUSSLING THEODOR; THEISSEN FERDINAND; WEIGERT WOLFGANG |
| OXAMIDE IS FORMED IN GOOD YIELDS UNDER ANHYDROUS CONDITIONS EMPLOYING (1) CYANOGEN, (2) A CARBOXYLIC ACID AND (3) A CARBOXYLIC ACID HALIDE OR HYDROGEN HALIDE. PREFERABLY SUPERATMOSPHERIC PRESSURE IS EMPLOYED.
|
||||||
| 369 | Preparation of dicarboxylic acid monoamides | US50257865 | 1965-10-22 | US3376337A | 1968-04-02 | PIERRE BROSSARD BERNARD |
| 370 | Process for separating adiponitrile from reaction mixture by stripping with ammonia | US34345164 | 1964-02-10 | US3350281A | 1967-10-31 | ROBERTO ROMANI; MARIO FERRI |
| 371 | Method for the preparation of amides | US30424963 | 1963-08-23 | US3296303A | 1967-01-03 | NEMEC JOSEPH W; RATERINK HARRY R; WISE STANLEY W |
| 372 | N, n-diethyl and n-methyl, n-butyl docosyl succinamate | US16228061 | 1961-12-26 | US3214460A | 1965-10-26 | MCGEE HANSEL L; SCHWARTZ PAUL M |
| 373 | Process for the production of monoamides of dicarboxylic acids | US74814158 | 1958-07-14 | US2929841A | 1960-03-22 | GODT JR HENRY C |
| 374 | Substituted malonic acid derivatives and process of preparing them | US16060737 | 1937-08-24 | US2228256A | 1941-01-14 | CHRISTIANSEN WALTER G |
| 375 | POLYIMIDE-BASED RESIN PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING RESIN FILM, AND AMIC ACID ESTER COMPOUND | PCT/JP2023025333 | 2023-07-07 | WO2025013140A1 | 2025-01-16 | NAGAYAMA SHINTARO; ISHIKAWA YOHEI; IWATA MARIKO |
| The polyimide-based resin precursor contains at least one of a constituent unit represented by formula (A1) or a constituent unit represented by formula (A2). At least one of R2 or R3 is an optionally substituted aromatic group, at least one of R2 or R3 is a group containing a photopolymerizable group, and R4 represents an aromatic group substituted with a group containing a photopolymerizable group. | ||||||
| 376 | METHODS OF MANUFACTURING A BIFUNCTIONAL COMPOUND | PCT/US2022038343 | 2022-07-26 | WO2023009521A1 | 2023-02-02 | CHEN CHUNGPIN HERMAN; DONG HANQING |
| This disclosure pertains to the preparation of bifunctional compounds (e.g., Compound 1), intermediates in the preparation of such compounds, and preparation of such intermediates. Compound 1 | ||||||
| 377 | CHEMICAL SUBSTANCES WHICH INHIBIT THE ENZYMATIC ACTIVITY OF HUMAN KALLIKREIN RELATED PEPTIDASE 6 (KLK6) | PCT/EP2017/075552 | 2017-10-06 | WO2018065607A1 | 2018-04-12 | MILLER, Aubry; SCHÜLER, Peter; DE VITA, Elena; GUNKEL, Nikolas |
The invention relates to compounds which are suitable for the treatment of a disease associated with kallikrein related peptidase 6 overexpression and to pharmaceutical compositions containing such compounds. The invention further relates to a kit of parts comprising such compounds or pharmaceutical compositions. |
||||||
| 378 | AROMATIC DERIVATIVES AS ANTI-MALARIAL | PCT/IN2015050140 | 2015-10-21 | WO2016063301A4 | 2016-08-11 | BHATTACHARYA ASISH KUMAR; ARATIKATLA ESWAR KUMAR; SRIVASTAVA KUMKUM; MANHAS ASHAN |
| The present invention discloses anti-malarial compound of formula (I) Formula (I) wherein, X is selected from O or NH; R1, R2, R3, R4 and R5 is selected from H or OMe or CH3, -CH2-O-CH2- or -CH=CH-CH=CH-; Y is selected from O or NH and R6, R7 is selected from the following compounds: or pharmaceutically acceptable salts thereof, process for preparation and a pharmaceutical composition containing the same. | ||||||
| 379 | AROMATIC DERIVATIVES AS ANTI-MALARIAL | PCT/IN2015/050140 | 2015-10-21 | WO2016063301A3 | 2016-04-28 | BHATTACHARYA, Asish Kumar; ARATIKATLA, Eswar Kumar; SRIVASTAVA, Kumkum; MANHAS, Ashan |
The present invention discloses anti-malarial compound of formula (I) Formula (I) wherein, X is selected from O or NH; R1, R2, R3, R4 and R5 is selected from H or OMe or CH3, -CH2-O-CH2- or -CH=CH-CH=CH-; Y is selected from O or NH and R6, R7 is selected from the following compounds: or pharmaceutically acceptable salts thereof, process for preparation and a pharmaceutical composition containing the same. |
||||||
| 380 | アミノ酸誘導体の製造方法 | PCT/JP2015/075653 | 2015-09-09 | WO2016039393A1 | 2016-03-17 | 関 雅彦 |
本発明は、光学純度の高いラコサミドを、高収率で、安価かつ安全に工業的に製造する方法を提供することを目的とする。 特定の中間体を用いることにより、光学純度の高いラコサミドを、高収率で、安価かつ安全に工業的に製造する方法を提供することで上記課題を解決する。また、ラコサミドの製造において有用な中間体を提供する。 |
||||||
QQ群二维码
意见反馈
意见反馈