1 |
Preparation of 4-substituted aryl olefins |
US315674 |
1989-02-27 |
US4965361A |
1990-10-23 |
Kevin J. Edgar |
Process is disclosed for the preparation of 4-substituted aryl olefins from 4-substituted aryl iodides. 4-Substituted aryl iodides are contacted with an olefin in an ester solvent in the presence of a catalyst system comprising a palladium compound and a Bronsted base. |
2 |
JPH04503674A - |
JP50522090 |
1990-02-22 |
JPH04503674A |
1992-07-02 |
|
|
3 |
Halogen-substituted cyclic ether compound and its preparation |
JP1615984 |
1984-02-02 |
JPS60161942A |
1985-08-23 |
ITOU HIROSHI; NITSUTA ATSUHIKO; TANAKA TOMIO; KAMIO HIDEO; TSUBOI KENJI |
NEW MATERIAL:The compound of formula I (R is carbon ring or heterocylic group; Z is alkylene, alkenylene, oxyalkylene or aminoalkylene; A is halogen, alkyl, alkenyl, haloalkyl, OH, alkoxy, cyano, amino, etc.; B is O, CO, S, SO or azo; X is halogen; l is 0W5; m is 4W20; α and β are 0W4 and α+β>1; p is 1W2; q is 0W1; when p is 1, then q is 0, and when p is 2, then q is 0W1; etc.).
EXAMPLE: 1-Bromo-4-furfuryloxybutane.
USE: An intermediate raw material useful to introduce various functional groups into amide compound, amine, OH-substituted compound, etc.
PREPARATION: The compound of formula I can be prepared economically in one step by reacting the OH-substituted compound of formula II with the halogen- substituted compound of formula III in an aprotic polar solvent in the presence of a strongly basic substance.
COPYRIGHT: (C)1985,JPO&Japio |
4 |
Process for the preparation of a secondary or tertiary hydroxylated
amine compound from a primary or secondary amine compound and a product
made by the process |
US268530 |
1994-07-06 |
US5594150A |
1997-01-14 |
Catherine David; Gilles Teral; Henry Ledon; Jean-Pierre Boiteux |
Process for the preparation of a hydroxylated secondary or tertiary amine compound having a hydroxyl function .beta. to the amine function, according to which a primary or secondary amine compound is reacted with a compound containing an epoxy function in the presence of a phase transfer catalyst. |
5 |
Phenyl-substituted hydroxy-cyclopentenone and a method of manufacturing a method for manufacturing the same, and phenyl-substituted hydroxy cyclopentanone |
JP5121794 |
1994-02-24 |
JP3541418B2 |
2004-07-14 |
史衛 佐藤 |
|
6 |
Phenyl-substituted hydroxycyclopentenones, production thereof and production of phenyl-substituted hydroxycycklopentanone |
JP5121794 |
1994-02-24 |
JPH07238045A |
1995-09-12 |
SATOU FUMIE |
PURPOSE:To obtain a novel intermediate for a phenyl-substituted prostaglandin E which is useful as a variety of medicines. CONSTITUTION:A compound is represented by formula I[Z<1> is H, a protecting group for OH; X<1> is H, halogen, 1-6C alkoxy, nitro; X<2> is a halogen,-Y<1>h(CR<1> R<2>)mAn(CH2)p, Y<2>q(CR<3>R<4>)rQs (Y<1>, Y<2> are O, S; A is a divalent group; R<1>-R<4> are H, a 1-4C alkyl; Q is H, cyano, OH; h, n, q, s are 0, 1; m, p, r are 0-5]. The compound of formula I is obtained by rearrangement of a furan derivative of formula II in the presence of an acid catalyst, isomerization under acidic or basic conditions and, when needed, protection of the hydroxyl group. A mixture of both antipodes of the compound of formula l is treated with an enzyme to give an optically active compound. |
7 |
Cyclic halogen-substituted ether compounds and methods of manufacturing the |
JP1615984 |
1984-02-02 |
JPH0710786B2 |
1995-02-08 |
伊藤 博; 賢次 坪井; 敦彦 新田; 富夫 田中; 秀雄 神尾 |
|
8 |
Preparation of N- [4-chloro-2-fluoro-5- (pentyloxy-carbonylmethyloxy) -phenyl] -3,4,5,6-tetrahydrophthalimides. |
DE3853605 |
1988-08-19 |
DE3853605T2 |
1995-10-19 |
FUNAKI YUJI; FUKUSHIMA MASAYUKI |
|
9 |
|
AT90905293 |
1990-02-22 |
ATE98209T1 |
1993-12-15 |
EDGAR KEVIN JOSEPH |
|
10 |
ENANTIOSELECTIVE PREPARATION OF ACETYLENIC OR OLEFINIC SUBSTITUTED CYCLOALKENYL DIHYDROXYBUTYRATES AND 4-HYDROXY-TETRAHYDROPYRAN-2-ONES |
AU2023292 |
1992-02-11 |
AU2023292A |
1992-09-15 |
ULLRICH JOHN W; REGAN JOHN R |
|
11 |
PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS |
CA2046643 |
1990-02-22 |
CA2046643A1 |
1990-08-28 |
EDGAR KEVIN J |
2046643 9009973 PCTABS00002 Process is disclosed for the preparation of 4-substituted aryl olefins from 4-substituted aryl iodides. 4-Substituted aryl iodides are contacted with an olefin in an ester solvent in the presence of a catalyst system comprising a palladium compound and a Bronsted base. |
12 |
|
BR8906055 |
1989-11-30 |
BR8906055A |
1990-06-26 |
AUSTIN PETER WILLIAM |
|
13 |
The production of N-[4-chloro-2-fluoro-5-(pentyloxycarbonylmethyloxy)phenyl]-3,4,5,6-tetrahydrophthalimide |
EP88113510.7 |
1988-08-19 |
EP0305826B1 |
1995-04-19 |
Funaki, Yuji; Fukushima, Masayuki |
|
14 |
Novel bicycloheptene derivatives and process for the preparation thereof |
AU4143100 |
2000-04-27 |
AU4143100A |
2000-11-17 |
YAGIHARA TOMIO; YAMANAKA HIROYUKI |
|
15 |
Photoactive benzene monomers |
IL11450495 |
1995-07-07 |
IL114504A |
1999-12-31 |
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16 |
FUEL COMPOSITIONS CONTAINING POLY(OXYALKYLENE) AROMATIC ETHERS |
CA2151713 |
1994-10-27 |
CA2151713A1 |
1995-05-04 |
|
Fuel compositions containing a major amount of hydrocarbons boiling in the gasoline or diesel range and an effective deposit-controlling amount of a poly(oxyalkylene) aromatic ether having formula (I) where A1 is nitro, amino, N-alkylamino wherein the alkyl group contains 1 to 6 carbon atoms, or N,Ndialkylamino wherein each alkyl group independently contains 1 to 6 carbon atoms; R1 and R2 are independently hydrogen, hydroxy, lower alkyl, or lower alkoxy; R3 and R4 are independently hydrogen or lower alkyl and each R3 and R4 is independently selected in each -O-CHR3-CHR4- unit; R5 is hydrogen, alkyl having 1 to 100 carbon atoms, phenyl, aralkyl having 7 to 100 carbon atoms or alkaryl having 7 to 100 carbon atoms, or an acyl group of formula (a) where R6 is alkyl having 1 to 30 carbon atoms, phenyl, aralkyl having 7 to 36 carbon atoms or alkaryl having 7 to 36 carbon atoms; n is an integer from 5 to 100; and x is an integer from 0 to 10. |
17 |
|
MX1833789 |
1989-11-13 |
MX173148B |
1994-02-02 |
AUSTIN PETER WILLIAM |
|
18 |
Preparation of 4-substituted aryl olefins. |
DE69005102 |
1990-02-22 |
DE69005102D1 |
1994-01-20 |
EDGAR KEVIN |
|
19 |
Compounds of use in the treatment of herrickschen syndrome. |
DE3778576 |
1987-03-26 |
DE3778576D1 |
1992-06-04 |
ABRAHAM DONALD J; CRAGOE JR; WOLTERSDORF JR |
|
20 |
PROCESS FOR PRODUCING POLYHYDROXY-BENZAYLOXY-PROPANOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS ACTIVE COMPONENT |
HU663689 |
1989-12-15 |
HUT53591A |
1990-11-28 |
PATIL GHANSHYAM; MATIER WILLIAM L; MAI KHUONG H X |
|