序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
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1 | 作为柴油十六烷改进剂的甘油和乙醇的醚的硝酸酯及其生产方法 | CN202080090484.7 | 2020-11-19 | CN114929844A | 2022-08-19 | 贝尔纳多·加尔旺西凯拉; 克里斯蒂安娜·内韦斯波托; 拉裴尔·贝泽拉德梅内塞斯; 马里托·戈梅斯朱尼尔; 卡洛斯·勒内克洛茨拉贝洛 |
本发明涉及甘油和乙醇的醚的硝酸酯作为柴油十六烷改进剂的用途及其生产方法,旨在由来自生物柴油生产的甘油生产添加剂,并为添加剂市场带来更经济且更有效的选择,从而促进柴油的点火并改进所述燃料的十六烷值。 | ||||||
2 | Selective manufacture of nitroalkane and nitroaromatic | JP19075384 | 1984-09-13 | JPS60130550A | 1985-07-12 | SHIYUUCHII POORU WAN; MAACHIN BII SHIYAAUIN |
3 | AT00948685 | 2000-07-14 | AT425213T | 2009-03-15 | HUFFMAN BRIAN; SCHULTZ ROSE; SCHLOM PETER; NOWICKI JAMES; HUNG JU-MING | |
4 | ИНГИБИТОРЫ ВИЧ-ИНТЕГРАЗЫ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ | RU2004119963 | 2002-12-06 | RU2284315C2 | 2006-09-27 | UOKER MAJKL A; BANVIL ZHAK; REMILLARD RODZHER; PLAMONDON SERZH |
FIELD: organic chemistry, biochemistry, virology. SUBSTANCE: invention relates to inhibition of human immunodeficiency virus (HIV) that is identified as etiological agent responsible for the acquired immunodeficiency syndrome (AIDS) that represents the lethal disease characterizing by damage of immune system, inability for the life safe and to resist against infections. Invention proposes inhibitors of integrase represented by the formula (I): wherein corresponding values of radicals are given in the invention description. The aim of the present invention involves providing preparing a pharmaceutical composition useful for inhibition of activity of HIV integrase that involves the therapeutically effective dose of compound of the formula (I) and their pharmaceutically acceptable salts, solvates and a pharmaceutically acceptable carrier. EFFECT: valuable medicinal properties of inhibitors. 16 cl, 6 sch, 42 ex | ||||||
5 | COMPOUND, COMPOSITION, PROCESS AND USE | IE344389 | 1989-10-25 | IE893443L | 1990-05-30 | |
6 | PROCESS FOR PREPARING 3-CHLORO-4-FLUORONITROBENZENE | EP88902565.6 | 1988-03-18 | EP0307481A1 | 1989-03-22 | ISHIKURA, Tsukasa; FUKUSHIMA, Tatuharu |
A process for preparing 3-chloro-4-fluoronitrobenzene, which comprises chlorinating 4-fluoronitrobenzene in the presence of: (1) iodine or its compound and iron or its compound, or (2) iodine or its compound and antimony or its compound. |
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7 | Dehydroxylierung von Nitroalkoholen in Nitroalkane | DE112013006019 | 2013-11-21 | DE112013006019B4 | 2021-04-22 | DAVIS PAUL; DESHPANDE RAJ; GREEN GEORG DAVID; PANDEY VANDANA |
Dehydroxylierungsverfahren zur Herstellung eines Nitroalkans von einem Nitroalkohol, das Folgendes beinhaltet:(A) Inkontaktbringen des Nitroalkohols mit einem Iodkatalysator, ausgewählt aus Iodwasserstoffsäure und Iod, in einer Reaktionszone unter Wasserstoffdruck; und(B) Erhitzen der Reaktionszone und des Inhalts auf eine Reaktionstemperatur zwischen 50°C und 250°C, um das Nitroalkan zu bilden. | ||||||
8 | Optiski tīra dietil[4-metil-1-nitropentan-2-il]malonāta iegūšanas paņēmiens | LV150126 | 2015-11-06 | LV15111B | 2016-08-20 | FOTINS JURIS; PETRENKO ALLA; MIRONOVA LABĪTE; ORBANE OLGA; LIEPIŅŠ VILNIS |
9 | Optiski tīra dietil[4-metil-1-nitropentan-2-il]malonāta iegūšanas paņēmiens | LV150126 | 2015-11-06 | LV15111A | 2016-03-20 | FOTINS JURIS; PETRENKO ALLA; MIRONOVA LABĪTE; ORBANE OLGA; LIEPIŅŠ VILNIS |
Izgudrojums attiecas uz optiski tīra dietil[4-metil-1-nitropentan-2-il]malonāta iegūšanas paņēmienu. Dotais izgudrojums attiecas uz asimetrisko savienojumu iegūšanas paņēmienu, kas ietver dikarbonilsavienojumu asimetrisku pievienošanu pie nitroalkēniem hirālā katalizatora klātbūtnē saskaņā ar Mihaela reakciju. | ||||||
10 | Reagents for heat activated polymer crosslinking | AU6215300 | 2000-07-14 | AU6215300A | 2002-01-30 | HUFFMAN BRIAN S; SCHULTZ ROSE ANN; SCHLOM PETER J; NOWICKI JAMES W; HUNG JU-MING |
11 | A process for the preparation of 3-chloro-4-fluoronitrobenzene. | DE3885823 | 1988-03-18 | DE3885823D1 | 1994-01-05 | ISHIKURA TSUKASA; FUKUSHIMA TATUHARU |
12 | GENERAL METHOD FOR INCREASING STEREOSELECTIVITY IN STEREOSELECTIVE REACTIONS | US12340455 | 2008-12-19 | US20090163741A1 | 2009-06-25 | Matthew P. Meyer; Hui Zhu |
This invention is directed to a method of performing a stereoselective reaction without use of a solvent comprising contacting a reactant with a chiral reagent under sonication conditions to form an excess of an enantiomer. | ||||||
13 | CONTINUOUS PROCESS FOR DECARBOXYLATING CARBOXYLIC ACIDS | US11961109 | 2007-12-20 | US20080214864A1 | 2008-09-04 | Marianne Omeis; Guenther Koehler; Manfred Neumann; Thomas Kuebelbaeck |
A continuous process for decarboxylating carboxylic acids proceeds by I.) initially charging a carbonyl compound as a catalyst in a solvent at reaction temperature, to obtain a catalyst solution; II.) metering a carboxylic acid into the catalyst solution as an aqueous solution, aqueous suspension or as a water-comprising solid, to obtain a reaction mixture; and III.) continuously removing a mixture of CO2, solvent, water and a reaction product or mixture of reaction products from the reaction mixture as a vapor. | ||||||
14 | Polyurea Compositions and Compounds for the Preparation Thereof | US11596325 | 2005-05-16 | US20080194859A1 | 2008-08-14 | Kenneth I. Sawyer; Robert J. Kupper |
The invention is directed to novel compounds that are used in the formation of polyurea compositions, including one-part and two-part polyurea compositions. The invention is also directed to polyureas formed from such compounds, cross-linked polyureas, and UV-stabilized polyureas. | ||||||
15 | Process of preparing 3-nitro benzoate compounds in lower alkanol | US714065 | 1996-09-11 | US5756810A | 1998-05-26 | John J. Baldwin; Michael H. J. Ohlmeyer; Ian Henderson |
A process for preparing t-butyl 4-(hydroxymethyl)-3-nitrobenzoate from t-butyl 4-(acetoxymethyl)-3-nitrobenzoate which comprises reacting t-butyl 4-(acetoxymethyl)-3-nitrobenzoate with hydrazine or hydrazine hydrate in a lower alkanol at 0.degree.-50.degree. C. | ||||||
16 | 1-aryloxy-3-alkylamino-2-propanol nitrate esters, the use thereof and corresponding pharmaceutical composition | US514267 | 1995-08-11 | US5639904A | 1997-06-17 | Maria Prat Quinones; Joan Pi Sallent; Dagmar Vedrilla Veit |
The 1-aryloxy-3-alkylamino-2-propanol nitrate esters, having formula I: ##STR1## the enantiomers and diastereoisomers and the therapeutically acceptable salts thereof, wherein R.sub.1 is a chain of general formula II --(CH.sub.2).sub.m --Z--R.sub.2, where: m is 1 or 2; Z is an --O-- ether, --CONH amide or --COO-- ester function; and R.sub.2 is a C.sub.2-3 straight or branched chain alkyl having at least one nitroxy group as substituent; and Ar is a benzene ring when Z is the ether or ester function, and a naphthalene ring when Z is the amide function, are of use for the treatment of cardiovascular affections. | ||||||
17 | nitratos de éteres de glicerol e etanol como melhoradores de cetano do diesel e processo de produção dos mesmos | BR102019025173 | 2019-11-28 | BR102019025173A2 | 2021-06-08 | BERNARDO GALVÃO SIQUEIRA; CARLOS RENE KLOTZ RABELO; CRISTIANA NEVES PORTO; MARLITO GOMES JUNIOR; RAPHAEL BEZERRA DE MENEZES |
a presente invenção está relacionada ao uso de nitratos de éteres de glicerol e etanol como melhoradores de cetano do diesel, e processo de produção dos mesmos, visando produzir um aditivo a partir do glicerol proveniente da produção de biodiesel e trazer ao mercado de aditivos uma opção mais econômica e eficiente para facilitar a ignição do diesel e melhorar o número de cetano do referido combustível. | ||||||
18 | Reagent for heat-activated crosslinking of polymeric | DE60041786 | 2000-07-14 | DE60041786D1 | 2009-04-23 | HUFFMAN BRIAN S; SCHULTZ ROSE ANN; SCHLOM PETER J; NOWICKI JAMES W; HUNG JU-MING |
19 | REAGENTS FOR HEAT ACTIVATED POLYMER CROSSLINKING | CA2385612 | 2000-07-14 | CA2385612A1 | 2002-01-24 | HUFFMAN BRIAN S; NOWICKI JAMES W; HUNG JU-MING; SCHLOM PETER J; SCHULTZ ROSE ANN |
The present invention is directed to nitrile-oxide precursor compounds, and their preparation and use as an irreversible cross-linking agent in polymers having appropriate functionality, i.e., alkenes, alkynes nitriles, and isocyanates. The present invention is also directed to the use of nitrile oxide compound in filled or unfilled applications such as pressure sensitive adhesives, reactive hot melts, polyurethane dispersions, thermosetting adhesives, thermoplastic adhesives or coatings. | ||||||
20 | Compound composition process and use | IE344389 | 1989-10-25 | IE63439B1 | 1995-04-19 | AUSTIN PETER WILLIAM |