子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 181 | Postopek za encimsko sintezo (7S)-3,4-dimetoksibiciklo(4.2.0)okta-1,3,5-trien-7-karboksilne kisline ter njena uporaba za sintezo ivabradina in njegovih soli | SI201430006 | 2014-02-27 | SI2772547T1 | 2015-10-30 | PEDRAGOSA MOREAU SANDRINE; LEFOULON FRANCOIS |
| 182 | Postopki in spojine za izdelavo inhibitorjev dipeptidil peptidaze IV in njihovih vmesnih spojin | SI200332399 | 2003-12-04 | SI2505579T1 | 2015-01-30 | VU TRUC CHI; KOLOTUCHIN SERGEI V; MAZZULLO JOHN A JR; WANG JIANJI; WONG KWOK; YU JURONG; ZHU JASON |
| 183 | POSTOPEK IN SPOJINE ZA PROIZVODNJO DIPEPTIDIL PEPTIDAZE IV INHIBITORJEV IN NJIHOVIH INTERMEDIATOV | SI200332363 | 2003-12-04 | SI1581487T1 | 2014-09-30 | VU TRUC CHI; BRZOZOWSKI DAVID B; FOX RITA; GODFREY JOLLIE DUAINE JR; HANSON RONALD L; KOLOTUCHIN SERGEI V; MAZZULLO JOHN A JR; PATEL RAMESH N; WANG JIANJI; WONG KWOK; YU JURONG; ZHU JASON; MAGNIN DAVID R; AUGERI DAVID J; HAMANN LAWRENCE G |
| 184 | New process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | NZ57844509 | 2009-07-16 | NZ578445A | 2011-01-28 | PEGLION JEAN-LOUIS; BAUDOIN OLIVIER; AUDIC NICOLAS; CHAUMONTET MANON; PICCARDI RICCARDO |
| Disclosed is a process for the preparation of functionalised benzocyclobutene compounds of formula (IV) where the variables are as disclosed in the specification. The process comprises the steps of subjecting a halogenated optionally substituted phenyl ring to a cyclisation reaction in the presence of a catalyst/ligand system comprising a palladium catalyst and an organic phosphine selected from tri-tert-butylphosphine, 2-biphenyl-di-tert-butylphosphine and 1,2,3,4,5-pentaphenyl-1`-(di-tert-butylphosphino)-ferrocene or a phosphomium salt of the said phosphines in the presence of a base in an organic solvent. Also disclosed are compounds that are functionalised benzocyclobutene intermediates in the process. | ||||||
| 185 | Sposób wytwarzania hemipentahydratu rizedronianu sodu | PL37447405 | 2005-04-19 | PL206916B1 | 2010-10-29 | IZYDORZAK MARCIN; MAJKA ZBIGNIEW; RECHNIO JUSTYNA; STAWIŃSKI TOMASZ |
| 186 | PHOTOCHROMIC MATERIALS | HK07108809 | 2007-08-14 | HK1104055A1 | 2008-01-04 | WANG FENG; GEMERT BARRY VAN; STEWART KEVIN J; KNOX CAROL L; CHOPRA ANU; BROWN PATRICK M |
| 187 | A process for the preparation of alpha, alpha-dialkyl-alpha-hydroxymethyl-carboxylic acid derivatives | DE502005000381 | 2005-11-24 | DE502005000381D1 | 2007-03-29 | BOEHM ANDREAS DR; PETERSEN HERMANN DR; STOHRER JUERGEN DR |
| 188 | AT05025658 | 2005-11-24 | AT353867T | 2007-03-15 | BOEHM ANDREAS DR; PETERSEN HERMANN DR; STOHRER JUERGEN DR | |
| 189 | COMPOSTOS DE CICLOPENTANO SUBSTITUIDOS, UTEIS COMO INIBIDORES DE NEURAMINIDASE | PT97931014 | 1997-06-13 | PT933993E | 2006-10-31 | BABU YARLAGADDA S; POORAN CHAND; MONTGOMERY JOHN A |
| 190 | Sposób wytwarzania hemipentahydratu rizedronianu sodu | PL37447405 | 2005-04-19 | PL374474A1 | 2006-10-30 | IZYDORZAK MARCIN; MAJKA ZBIGNIEW; RECHNIO JUSTYNA; STAWINSKI TOMASZ |
| 191 | Method of preparing amino carboxylic acids, such as N-(phosphonomethyl)glycine, via a carboxymethylation step | NZ33564998 | 1998-02-12 | NZ335649A | 2001-01-26 | STERN MICHAEL K; JOHNSON TODD J; ROGERS MICHAEL D; FOBIAN YVETTE M; LEVINE JEFFREY A; MORGENSTERN DAVID A |
| Process for the preparation of an N-acyl amino carboxylic acid by means of a carboxymethylation reaction. In this reaction, a reaction mixture is formed which contains a base pair, carbon monoxide, hydrogen and an aldehyde with the base pair comprising a carbamoyl compound and a carboxymethylation catalyst precursor. In a preferred embodiment, the carbamoyl compound and aldehyde are selected to yield an N-acyl amino carboxylic acid which is readily converted to N-(phosphonomethyl)glycine, or a salt or ester thereof. The carbamoyl compound has the general formula as seen above wherein: R1 is hydrogen, hydrocarbyl, substituted hydrocarbyl, -NR3R4, -OR5, or -SR6; R2 and R2a are independently hydrogen, hydrocarbyl, or substituted hydrocarbyl; R3 and R4 are independently hydrogen, hydrocarbyl, or substituted hydrocarbyl; R5 and R6 are independently hydrogen, hydrocarbyl, substituted hydrocarbyl, or a salt-forming cation; provided, however: (1) at least one of R2 and R2a is hydrogen, hydroxymethyl, amidomethyl, or another substituent which, under the carboxymethylation reaction conditions, is capable of producing an N-H bond, or (2) R1 is -NR3R4 and at least one of R3 and R4 is hydrogen, hydroxymethyl, amidomethyl, or another substituent, which, under the carboxymethylation reaction conditions, is capable of producing an N-H bond. | ||||||
| 192 | MACROLIDE COMPOUNDS, A COMPOSITION WITH ANTIBIOTIC ACTIVITY, A VETERINARY COMPOSITION, INJECTO-ACARICIDE-NEMATOCIDAL COMPOSITION AND METHOD OF DESTRUCTION OF TICKS AND-OR INSECTS, NEMATODES | GEAP1993001498 | 1993-08-25 | GEP19981388B | 1998-11-10 | NOBLE DAVID; PORTER NEIL; TILEY EDWARD P; FLETTON RICHARD A; WARD JOHN B; RAMSAY MICHAEL V J; NOBLE HAZEL M; PEREIRA OSWY Z; SUTHERLAND DEREK R |
| 1. Technical result Reception of compounds and compositions possessing antibiotic activity, veterinary compositions and insect acaricide nematocidal compositions. 2. Essence Macrolide compounds of the formula 1: or its salts where R1 - methyl, ethyl or isopropyl, R2 – hydrogen, C1-C8 - alkyl or C1-C8 - alkenyl, thus the group = NOR2 is in the Е-configuration, ОR3- hydroxy, ОR4, ОСОR4 or ОСОNR8R9, R4-C1-C6 - alkyl, R8 and R9 independently mean hydrogen or C1-C4 - alkyl. A composition having antibiotic activity, a veterinary composition, insectоacaricidonematicidal composition and a method of destruction of ticks and-or insects, nematodes in which in the form of active connections the compounds of the formula 1 are used. 3. Field of Application Medicine, veterinary science, pharmacology. | ||||||
| 193 | Method of preparing amino carboxylic acids | AU6326498 | 1998-02-12 | AU6326498A | 1998-09-08 | STERN MICHAEL K; JOHNSON TODD J; ROGERS MICHAEL D; LEVINE JEFFREY A; MORGENSTERN DAVID A; FOBIAN YVETTE M |
| 194 | METHOD OF PREPARING AMINO CARBOXYLIC ACIDS | CA2271201 | 1998-02-12 | CA2271201A1 | 1998-08-20 | STERN MICHAEL K; FOBIAN YVETTE M; JOHNSON TODD J; ROGERS MICHAEL D; MORGENSTERN DAVID A; LEVINE JEFFREY A |
| Process for the preparation of an N-acyl amino carboxylic acid by means of a carboxymethylation reaction. In this reaction, a reaction mixture is formed which contains a base pair, carbon monoxide, hydrogen and an aldehyde with the base pair conprising a carbamoyl compound and a carboxymethylation catalyst precursor. In a preferred embodiment, the carbamoyl compound and aldehyde are selected to yield an N-acyl amino carboxylic acid which is readily converted to N-(phosphonomethyl)glycine, or a salt or ester thereof. | ||||||
| 195 | CYKLOHEXANDIONKARBOXYLSYRADERIVAT MED VAEXTREGLERANDE EGENSKAPER HOS VAEXTER | FI844521 | 1984-11-16 | FI89163C | 1993-08-25 | BRUNNER HANS-GEORG |
| 196 | Cyclohexandioncarboxylsyrederivater, process for their preparation and their use as plant growth regulators | DK248084 | 1984-05-17 | DK166775C | 1993-07-12 | BRUNNER HANS-GEORG |
| 197 | Cyclohexandioncarboxylsyrederivater, process for their preparation and their use as plant growth regulators | DK248084 | 1984-05-17 | DK166775B1 | 1993-07-12 | BRUNNER HANS-GEORG |
| 198 | CYCLOHEXANEDIONE-CARBOXYLIC-ACID DERIVATIVES HAVING A HERBICIDAL AND PLANT GROWTH REGULATING ACTIVITY | CY162192 | 1992-07-10 | CY1621A | 1992-07-10 | |
| 199 | CYCLOHEXANDION-CARBONSAEUREDERIVATE MIT HERBIZIDER UND DAS PFLANZENWACHSTUM REGULIERENDER WIRKUNG. | AT84810233 | 1984-05-14 | ATE40106T1 | 1989-02-15 | BRUNNER HANS-GEORG |
| 200 | CYCLOHEXANDION-CARBONSAEUREDERIVATE MIT HERBIZIDER UND DAS PFLANZENWACHSTUM REGULIERENDER WIRKUNG. | AT84810233 | 1984-05-14 | AT40106T | 1989-02-15 | BRUNNER HANS-GEORG |
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