序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
101 Stabilized adducts of menadione bisulfite with p-aminobenzoic acid or adenine US518769 1983-08-02 US4577019A 1986-03-18 Enrico Bruschi
Stabilized adducts of K vitaminic compounds, as menadione bisulfite or a derivative thereof and stabilizing vitamins as, particularly, nicotine amide or nicotinic acid. Feed compositions containing the same. Process for their preparation.
102 Binucleating ligand-metal complexes as oxidation catalysts US659396 1984-10-10 US4545937A 1985-10-08 John E. Bulkowski
There is taught a class of homogeneous oxidation catalysts characterized by the presence therein of two chelated cations of Cu(I) in each molecule.
103 Oxidation process of reactive aromatics with reactivation of the catalyst using potassium permanganate US403615 1982-07-23 US4477380A 1984-10-16 Ulrich Knips; Bertram Bohmer; Roland Herzberg
In the oxidation of reactive aromatics with molecular oxygen in carboxylic acid solution in the presence of a catalyst consisting of a cobalt compound and possibly with addition of a manganese and a bromine compound suitable as Co-catalyst, an inactivation of the catalyst system readily occurs. This is prevented in that after each reaction cycle the catalyst is reactivated by treatment with a strong oxidant and the water formed in the reaction is removed by distillation.
104 Quinone compounds and their use in suppressing the production of SRS-A in mammals US248042 1981-03-26 US4393075A 1983-07-12 Shinji Terao; Mitsuru Shiraishi; Yoshitaka Maki
New quinone compounds of the formula: ##STR1## wherein R.sup.1 is methyl or methoxy, or the two R.sup.1 groups jointly represent --CH.dbd.CH--CH.dbd.CH--; X is --CH.dbd.CH-- or --C.dbd.C--; Y.sup.1 is hydrogen, hydroxyl, carboxyl, cyano, acyloxy or --COZ in which Z is amino which may be substituted; m is zero or an integer of 1 to 3; n is zero or an integer of 1 to 10; n' is an integer of 1 to 5; k is an integer of 1 to 3; and when k is 2 or 3, n' is optionally variable within the range of 1 to 5 in each occurrence of the --X--(CH.sub.2).sub.n' group; and their hydroquinone forms and salts, have useful physiological activities such as antiasthmatic, antiallergic and bloodpressure decreasing activities.
105 Substituted ortho-quinone dimer US62333 1979-07-31 US4362668A 1982-12-07 Richard J. Lee
Ortho-quinones with alkyl, olefin polymer, or halogen substituents and a process for the preparation of these compounds comprising a base catalyzed halogen oxidation of alkylated phenol.
106 Manufacture of pyranthrones US3673220D 1970-10-09 US3673220A 1972-06-27 BOCK GUSTAV
A new process for the manufacture of pyranthrones (I) from 2,2'' -dialkyl-1,1''-dianthraquinonyls (II) by heating (II) at from 150* to 210* C. in polar organic solvents in the presence of alkali metal acetates.
107 METHOD FOR MINIMIZING FOULING, CORROSION, AND SOLVENT DEGRADATION IN LOW-TEMPERATURE REFINERY AND NATURAL GAS PROCESSES PCT/US2020/065184 2020-12-16 WO2021126892A1 2021-06-24 SORIA, John

A method of oxygen scavenging, the method (i) providing an oxygen scavenger composition; and (ii) adding the oxygen scavenger composition to an aqueous feed and/or a hydrocarbon feed of a hydrocarbon processing system.

108 MITOCHONDRIA-TARGETED ATOVAQUONE: A MORE POTENT AND MORE EFFECTIVE ANTITUMOR, ANTIMICROBIAL, AND ANTIMALARIAL DRUG PCT/US2020/057363 2020-10-26 WO2021081500A1 2021-04-29 KALYANARAMAN, Balaraman; CHENG, Gang; HARDY, Micael Joël

The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provided. Methods of enhancing an anti-tumor immune response by administering mito-ATO are further provided.

109 基亚甲基环己烷1,3-二化合物的用途 PCT/CN2018/087452 2018-05-18 WO2018214814A1 2018-11-29 罗成; 乐立艳; 万伟; 张元元; 蒋华良; 陈凯先

基亚甲基环己烷1,3-二化合物的用途,具体涉及下式(I)所示化合物或其药学上可接受的盐单独或者与其他药物联合在制备调节细胞自噬及治疗细胞自噬,特别是哺乳动物ATG8同源蛋白,相关的疾病的药物中的用途。

110 INHIBITORS OF APURINIC/APYRIMIDINIC ENDONUCLEASE 1 (APE1) AND THEIR USE PCT/GB2011/052386 2011-12-02 WO2012073041A3 2012-06-07 MADHUSUDAN, Srinivasan; FISCHER, Peter; LAUGHTON, Charles

The invention provides a compound with the structural formula of any one of Formula 1 to Formula 18 or a pharmaceutically acceptable salt thereof, and uses thereof.

111 METHODS FOR PREPARING HYPERICIN PCT/US2010/048937 2010-09-15 WO2011034922A1 2011-03-24 TOBIA, Alfonso, J.; CABANA, Bernard, E.; VADLAPATLA, Venkata; CONNOLLY, Ronald, H.

The present invention provides a method for making hypericin comprising the steps of converting a protohypericin to a protohypericin salt, and irradiating the protohypericin salt with visible light to form hypericin. The present invention also provides an apparatus comprising a transparent column having a top end and a bottom end, an inlet attached to the column at the top end to flow reactants into the column, a container attached to the column at the bottom end; and a visible light source positioned to cast light on to the column. The present invention further provides a method for making hypericin using said apparatus.

112 Vitamin E acetate intermediates 2,3,5-trimethylbenzoquinone synthesis method IES20180121 2018-04-04 IES20180121A2 2019-06-12 FEI PENG
The present invention discloses vitamin E acetate intermediates 2,3,5-trimethylbenzoquinone synthesis method by 2-methyl-4-hydroxy-3,6-dimethylol toluene, 2,5-hexanediol solution were added to the reaction vessel, controlled the stirring speed, raising the solution temperature, added molybdenum disulfide powder, raised the temperature of the solution, kept for 90-140 min; extracted with N-methylaniline solution for several times, washed with 2-methylpyridine solution for several times, standing for stratification, recrystallized in 3-methyl-2-butanol solution, dehydrated with dehydrating agent, finally got finished product 2, 3,5 -trimethyl benzoquinone.
113 ПРОИЗВОДНЫЕ 2-ГИДРОКСИ-3-ФЕНИЛЭТИНИЛТИО (СЕЛЕНО)-1,4-ХИНОНОВ В КАЧЕСТВЕ ПОВЕРХНОСТНО-АКТИВНЫХ ВЕЩЕСТВ И МОЮЩЕЕ СРЕДСТВО ИХ СОДЕРЖАЩЕЕ RU2013152521 2013-11-26 RU2547823C1 2015-04-10 ZACHINJAEV JAROSLAV VASIL EVICH; KHARITONENKO ALEKSANDR LEONIDOVICH; SERGIENKO JURIJ VLADIMIROVICH; TITOVA TAMILA SEMENOVNA; ZACHINJAEVA ANNA VLADIMIROVNA; KOVALEVA LJUDMILA IVANOVNA
Предложеныпроизводные 2-гидрокси-3-фенилэтинилтио(селено)-1,4-хиноновв качествеповерхностно-активныхвеществв составемоющегосредствадляочисткинефтеналивногооборудованияотзагрязненийорганическойи неорганическойприроды. Такжепредложеномоющеесредстводляочисткинефтеналивногооборудованияотзагрязненийорганическойи неорганическойприроды, включающеесиликатнатрия, карбонатнатрия, смачивательОП-10, поверхностно-активноевеществои воду, причемв качествеповерхностно-активноговеществаоносодержитприследующемсодержанииперечисленныхкомпонентов, мас.%: силикатнатрия - 0,70-0,75, карбонатнатрия - 3,5-3,75, смачивательОП-10 - 0,23-0,25, производное 2-гидрокси-3-фенилэтинилтио(селено)-1,4-хинонов - 0,23-0,25, вода - остальное. Техническийрезультат - полнаяочисткаочищаемыхповерхностейприминимальномрасходемоющегосредстваи сокращениевремениееобработки. 2 н.п. ф-лы, 1 табл.
114 ПРИМЕНЕНИЕ АЛЮМИНИЯ АЗОТНОКИСЛОГО В КАЧЕСТВЕ УСИЛИТЕЛЯ ДЕЙСТВИЯ АЗОТА И КАК СИСТЕМНОГО АКТИВАТОРА МОРФОГЕНЕТИЧЕСКИХ ПРОЦЕССОВ РАСТЕНИЙ И УДОБРЕНИЕ НА ЕГО ОСНОВЕ UAA201001780 2010-02-19 UA96494C2 2011-11-10 MAZILNIKOV HENNADII VASYLIOVYCH; SHYMANSKYI ARKADII PETROVYCH; LYKHODID YURII ANATOLIIOVYCH; MELNYK STEFANIIA STEFANIVNA
Применениеалюминияазотнокислогов качествеусилителядействияазотаи каксистемногоактиватораморфогенетическихпроцессоврастенийи удобрение, содержащееалюминийазотнокислый, гидрохинон, ортованадатнатрияи гидроксидкалия.
115 Sposób wytwarzania 2-hydroksy-3-(3-metylobuten-2-yl)naftochinonu-1,4 PL38139506 2006-12-27 PL207841B1 2011-02-28 BORUSZCZAK ZYGMUNT
116 Perylenequinone derivatives and uses thereof GB0802753 2006-07-28 GB2442915B 2009-12-16 SHARMA SANJAY K; WOO THOMAS; NAICKER SELVARAJ
The present invention relates to compounds which are perylenequinone derivatives, their stereoisomers and atropisomers. These compounds can be particularly useful as photosensitizers or sononsensitizers in photodynamic or sonodynamic therapy. The invention also relates to various methods for using these compounds in photodynamic and/or sonodynamic therapy. The compounds also are useful as therapeutic agents for treating various hyperproliferative disorders.
117 DERIVATIVES OF 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE, METHOD FOR SYNTHESIS AND PHARMACEUTICAL COMPOSITION UA20040907252 2003-02-04 UA79448C2 2007-06-25 DASSONVILLE ALEXANDRA; BRETECHE ANNE; DUFLOS MURIEL; LE BAUT GUILLAUME; PFEIFFER BRUNO; RENARD PIERRE; LEVENS NIGEL; HUSSON-ROBERT BERNADETTE
The invention concerns a compound of formula (I), wherein: R1 and R2, identical or different, represent each a hydrogen atom or an acyl or alkyl group; Ar represents an aryl or heteroaryl group; A represents a group selected from formula (II); R4 represents a hydrogen atom or an alkyl group; R5 represents a hydrogen atom or a group selected among alkyl, aryl and heteroaryl; R3 represents an aryl, heteroaryl, dicyclopropylmethyl or benzhydryl group, or A-R3 represents an optionally substituted naphthyl group, excluding 2,5-dihydioxy-3-(4-methoxyphenyl)-6-(2-phenylethenyl)-1,4-benzoquinone, 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-naphthyl)-1,4-benzoquinone, and 2,5-dihydroxy-3 (2-naphthyl)-6-phenyl-1,4-benzoquinone. The inventive compound is useful for preparing medicines.
118 BRPI0502766 2005-06-20 BRPI0502766A 2007-02-21 VARGAS MARIA DOMINGUES; PINTO ANGELO DA CUNHA; CAMARA CELSO AMORIM; CARVALHO JOAO ERNESTO DE; KOHN LUCIANA KONECNY
119 Perylenequinone derivatives and uses thereof AU2006279189 2006-07-28 AU2006279189A1 2007-02-15 SHARMA SANJAY K; WOO THOMAS; NAICKER SELVARAJ
120 OA9800080 1998-06-12 OA10696A 2002-11-26 BOUTHERIN-FALSON ODILE; DESQUAND-BILLIALD STEPHANIE; FAVROU ANITA; FINET MICHEL; TEMBO OLIVIER; TORREGROSA JEAN LUC; YANNIC-ARNOULT SYLVIE; DOMAGALA-LE MARQUER FLORENCE
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