序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 基亚甲基环己烷1,3-二化合物的用途 CN201880033796.7 2018-05-18 CN111108083A 2020-05-05 罗成; 乐立艳; 万伟; 张元元; 蒋华良; 陈凯先
发明涉及基亚甲基环己烷1,3-二化合物的用途,具体涉及下式(I)所示化合物或其药学上可接受的盐单独或者与其他药物联合在制备调节细胞自噬及治疗细胞自噬,特别是哺乳动物ATG8同源蛋白,相关的疾病的药物中的用途。
2 一种木质纤维原料的生物炼制方法 CN200910084431.X 2009-05-15 CN101555667A 2009-10-14 刘德华; 赵雪冰
一种木质纤维原料的生物炼制方法,包括以下步骤:(1)破碎和筛分原料,得到长纤维、短纤维和粉末;(2)采用化处理两步法处理步骤(1)所得到的长纤维,制成纸浆;和/或对步骤(1)所得的短纤维、粉末和步骤(2)所得的超细纤维和部分良浆进行同步糖化发酵,制得乙醇。在上述方法中,从碱处理后的黑液制得碱木素,氧化处理后的黑液回收溶剂并制得氧化木素。使用本发明的方法,可将木质纤维原料综合利用于生产纸浆、乙醇和木素产品。所得纸浆比同种原料的硫酸盐浆具有更高的得率和更好的纸浆性能。该纸浆在较少的纤维素酶用量下即可得到较高的酶解率。本发明提供的方法无硫、氯元素,同时减少了的排放,具有很好的环境友好性。
3 在低温炼油厂和天然气加工中使结垢腐蚀溶剂降解最小化的方法 CN202080088753.6 2020-12-16 CN114787325A 2022-07-22 J·索里亚
一种清除的方法,所述方法包括(i)提供氧清除剂组合物;和(ii)将所述氧清除剂组合物加入到加工系统的性进料和/或烃进料中。
4 基亚甲基环己烷1,3-二化合物的用途 CN201880033796.7 2018-05-18 CN111108083B 2022-07-15 罗成; 乐立艳; 万伟; 张元元; 蒋华良; 陈凯先
发明涉及基亚甲基环己烷1,3‑二化合物的用途,具体涉及下式(I)所示化合物或其药学上可接受的盐单独或者与其他药物联合在制备调节细胞自噬及治疗细胞自噬,特别是哺乳动物ATG8同源蛋白,相关的疾病的药物中的用途。
5 一种木质纤维原料的生物炼制方法 CN200910084431.X 2009-05-15 CN101555667B 2011-03-30 刘德华; 赵雪冰
一种木质纤维原料的生物炼制方法,包括以下步骤:(1)破碎和筛分原料,得到长纤维、短纤维和粉末;(2)采用化处理两步法处理步骤(1)所得到的长纤维,制成纸浆;和/或对步骤(1)所得的短纤维、粉末和步骤(2)所得的超细纤维和部分良浆进行同步糖化发酵,制得乙醇。在上述方法中,从碱处理后的黑液制得碱木素,氧化处理后的黑液回收溶剂并制得氧化木素。使用本发明的方法,可将木质纤维原料综合利用于生产纸浆、乙醇和木素产品。所得纸浆比同种原料的硫酸盐浆具有更高的得率和更好的纸浆性能。该纸浆在较少的纤维素酶用量下即可得到较高的酶解率。本发明提供的方法无硫、氯元素,同时减少了的排放,具有很好的环境友好性。
6 1,4-二氢-1,4-二-1H-的三环衍生物的应用,由其获得的新颖化合物,和它们在治疗中的应用 CN96198894.0 1996-12-10 CN1204323A 1999-01-06 O·布蒂埃林法尔森; S·迪斯匡得-比亚阿多; A·法夫罗; M·菲内; O·滕博; J·L·托雷格罗斯; S·扬尼克-阿尔努; F·多马加瓦-勒马克
具有通式(Ⅰ)的三环衍生物及其药学上可接受的盐的治疗应用,用于治疗与静脉功能缺陷和/或炎性浮肿。通式(Ⅰ)中,A是硫或原子、或是R3N基(其中的R3是氢原子、C1-C5的烷基、或是取代或未取代的芳环、或是取代或未取代的杂芳环);R1是C1-C5的烷基、或是R4NH基,其中的R4是氢原子、C1-C5的烷基、或取代或未取代的芳环、或取代或未取代的杂芳环,或是可被或不被一个或多个受体或给体基团取代的芳环、或有一个或多个杂原子的能被或不被受体或给体取代的杂芳环;R2是氢原子、卤原子、C1-C5的烷基、能被或不被C1-C5的烷基取代的氧原子、或NR5R5’基,其中的R5和R5’可相互独立地分别是氢原子、氧原子,或单价的C1-C5的有机基。
7 Production of quinones JP21505189 1989-08-23 JPH0381246A 1991-04-05 KOMIYAMA TADASHI; SUGIYAMA EIICHI; KUBOYAMA HISAHARU; TOKUMOTO SHUICHI
PURPOSE: To obtain the subject compounds for, synthesis of hydroquinone useful in photograph industry with a high selectivity without a problem of corrosion of metallic materials by reacting phenol with oxygen in the presence of a specified catalyst. CONSTITUTION: Using copper oxide and boron oxide as the catalyst, phenol or a substituted phenol is reacted with oxygen (Pure oxygen, air or nitrogen- diluted oxygen is used as the oxygen source) usually at 0-150°C, preferably at 10-100°C to obtain the objective compound. The reaction pressure may be ordinary pressure, an applied one or a reduced one and the pressure of oxygen is usually 0.1-500kg/cm 2G. In case of the non-substituted phenol, 20kg/cm 2≤200kg/cm 2 is preferable as the pressure of oxygen. In addition, the above-mentioned catalyst is produced, e.g. by a method where cuprous oxide or cuprous hydroxide is mixed with boron oxide. The atomic ratio of boron to copper is 0.01-100g atom boron based on 1g atom copper. COPYRIGHT: (C)1991,JPO&Japio
8 Hannoseihokozokukagobutsunosankaho JP50113982 1982-03-23 JPH0237903B2 1990-08-28 KUNIPUSU URURITSUHI; BEEMAA BERUTORAMU; HERUTSUBERUKU ROORANDO
9 JPS6011895B2 - JP6434580 1980-05-15 JPS6011895B2 1985-03-28 SUGITA SHIGEO; TANABE KENICHI; NAKAISHI TERUO; KOSHIDA KAZUO
10 JPS58500525A - JP50113982 1982-03-23 JPS58500525A 1983-04-07
11 Addition product of vitamin k compound and stabilization vitamin*its manufacture and its stabilized addition product JP9175379 1979-07-20 JPS5527180A 1980-02-27 ENRIKO BURUTSUCHI
12 METHOD FOR MINIMIZING FOULING, CORROSION, AND SOLVENT DEGRADATION IN LOW-TEMPERATURE REFINERY AND NATURAL GAS PROCESSES EP20829161.7 2020-12-16 EP4077598A1 2022-10-26 SORIA, John
A method of oxygen scavenging, the method (i) providing an oxygen scavenger composition; and (ii) adding the oxygen scavenger composition to an aqueous feed and/or a hydrocarbon feed of a hydrocarbon processing system.
13 MITOCHONDRIA-TARGETED ATOVAQUONE: A MORE POTENT AND MORE EFFECTIVE ANTITUMOR, ANTIMICROBIAL, AND ANTIMALARIAL DRUG EP20880080.5 2020-10-26 EP4048246A1 2022-08-31 KALYANARAMAN, Balaraman; CHENG, Gang; HARDY, Micael Joël
The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provided. Methods of enhancing an anti-tumor immune response by administering mito-ATO are further provided.
14 Organic conductive complex EP89111686.5 1989-06-27 EP0350709B1 1994-09-21 Matsuoka, Masaru; Kitao, Teijiro; Shimizu, Yo c/o Osaka Works of
15 퀴논 유도체의 제법 KR1019820000537 1982-02-09 KR100025900B1 1988-08-18 와따나베마사즈미; 이마다이스께
16 비스-아마노 메틸- 안트라퀴논 유도체의 제조 방법 KR1019810004526 1981-11-23 KR1019830007489A 1983-10-21 에르하르트빈켈만
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17 Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array US16016403 2018-06-22 US10724143B1 2020-07-28 Karl Maurer; John J. Cooper
There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.
18 Stabilization of pygas for storage US12345567 2008-12-29 US08187346B2 2012-05-29 James R. Butler
A method for stabilizing pyrolysis gasoline in storage involves adding an effective amount of a quinone methide compound to the pyrolysis gasoline. The quinone methide does not require oxygen for activity. Embodiments of the quinone methide do not contain nitrogen and will have a reduced tendency for ammonia production.
19 Polymorphs of atovaquone and process of preparation thereof US10569036 2004-07-16 US07847112B2 2010-12-07 Narayana Rao Mantripragada; Dhananjay Govind Sathe; Venkatasubramanian Radhakrishnan Tarur; Kamlesh Digambar Sawant; Gautam Ramjibhai Patel
Novel crystalline forms of anti Pneumocystis carinii compound (2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone) commonly known as Atovaquone and methods for producing the same is disclosed herein. This also provides pharmaceutical compositions comprising the said polymorphs of Atovaquone and method of treating Pneumocystis carinii pneumonia, the method comprising administering to a warm blooded animal an effective amount of a product-by-process composition of matter comprising polymorphic forms of Atovaquone.
20 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME US11693306 2007-03-29 US20080093985A1 2008-04-24 Hironobu MORISHITA; Hisayuki Kawamura; Chishio Hosokawa
A material for an organic electroluminescent device including a quinone derivative represented by the following formula (1), (2) or (3): wherein R1 to R16 are each a hydrogen atom, a halogen atom, a cyano group, an alkoxy group, a substituted or unsubstituted aryloxy group, an alkyl group, a fluoroalkyl group, an aryl group or a heterocyclic group; provided that at least one of R1 to R4, at least one of R5 to R10 or at least one of R11 to R16 is an aryloxy group; and X is a substituent represented by any one of the following formulas (a) to (f): wherein R17 to R19 are a hydrogen atom, an alkyl group, or aryl group; and R18 and R19 may be bonded together to form a ring.
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