专利汇可以提供Novel antibiotic ans-127 a substance and its preparation专利检索,专利查询,专利分析的服务。并且PURPOSE: To separate and to collect the titled antibiotic from a culture, by cultivating a bacterium belonging to the genus Streptomyces, capable of producing the titled novel antibiotic.
CONSTITUTION: A bactermium such as Streptomyces Sp. ANS-127 (FERM-P 5901), etc., belonging to the genus Streptomyces, capable of producing a novel antibiotic ANS-127A substance, is cultivated. In the cultivation, aerated spinner culture is carried out in a pH near neutrality in a medium comprising a carbon source such as dextrin, glucose, etc., a nitrogen source such as peptone, soybean powder, meat extract, etc., an inorganic salt, etc. The culture is filtered, a solvent such as ethyl acetate, chloroform, etc. is added to the prepared filtrate, and the prepared extracted solution is concentrated under reduced pressure by utilizing the difference of solubility, to give a raw extract of the desired ANS-127A substance, which is purified by adsorption chromatography, etc.
COPYRIGHT: (C)1982,JPO&Japio,下面是Novel antibiotic ans-127 a substance and its preparation专利的具体信息内容。
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