GLUCOSYLCERAMIDE SYNTHASE INHIBITORS |
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申请号 | EP12760259 | 申请日 | 2012-03-16 | 公开(公告)号 | EP2685986A4 | 公开(公告)日 | 2015-03-04 |
申请人 | GENZYME CORP; | 发明人 | BOURQUE ELYSE; CELATKA CASSANDRA; HIRTH BRADFORD; METZ MARKUS; ZHAO ZHONG; SKERLJ RENATO; XIANG YIBIN; JANCISICS KATHERINE; MARSHALL JOHN; CHENG SENG; SCHEULE RONALD; CABRERA-SALAZAR MARIO; GOOD ANDREW; | ||||
摘要 | The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer. | ||||||
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说明书全文 |