Substituted flavonoid compound, its salt, its production and medicine containing them专利检索- 杂环化合物含有硒原子或碲原子作为仅有的杂环原子的环专利检索查询-专利查询网

Substituted flavonoid compound, its salt, its production and medicine containing them
申请号	JP8783889	申请日	1989-04-06	公开(公告)号	JPH026473A	公开(公告)日	1990-01-10
申请人	Lipha (Lyon Ind Pharmaceut);			发明人	FUIRITSUPU BURIETSUTO; JIINNJIYAKUE BERUSERON; FURANSOWA KOROONE;
摘要	NEW MATERIAL: A compd. represented by formula I [wherein X is N, O, Se or S(O) n (n; 0-2), R 1 is H, alkyl, phenyl or naphthyl, R 2 is H, phenyl, OH or alkyl, R 3 and R 4 are H, alkyl, OH, alkoxy or halogen, R 5 is H, alkyl, CN or COOR 10 (wherein R 10 is H or alkyl), R 6 is H, alkyl, alkylene-CN or COOR 10 and R 7 is CO-alkyl, S-alkyl, SH or S-CO-alkyl] and its salt. EXAMPLE: Oxo-1-phenyl-3-(1H)-naphtho(2,1-b)-pyran-5-acetic acid. USE: An anti-cancer drug and a treatment agent of a disease associated with immune abnormality. PROCESS: For example, a compd. represented by formula II is reacted with an alkaline nitrile component and the reaction product is hydrolyzed to obtain a compd. represented by formula III belonging to the compd. represented by the formula I. COPYRIGHT: (C)1990,JPO
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