METHODS AND COMPOSITIONS FOR INHIBITING 5-g(a)-REDUCTASE ACTIVITY. |
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申请号 | EP93910950 | 申请日 | 1993-04-30 | 公开(公告)号 | EP0652749A4 | 公开(公告)日 | 1997-04-09 |
申请人 | ARCH DEV CORP; | 发明人 | LIAO SHUTSUNG; LIANG TEHMING; | ||||
摘要 | Disclosed are a novel class of anti-androgenic compounds including saturated and unsaturated fatty acids, their derivatives, and synthetic analogs, according to the following formula: CH3-(CH2)a-(CR1R2CH=CH)b-(CH2)c-COOH, wherein R1 and R2 are each either hydrogen or a halogen; wherein a and c are integers from 0-9; wherein b is an integer from 1-6, provided that 12 | ||||||
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