METHODS AND COMPOSITIONS FOR INHIBITING 5-g(a)-REDUCTASE ACTIVITY.

申请号 EP93910950 申请日 1993-04-30 公开(公告)号 EP0652749A4 公开(公告)日 1997-04-09
申请人 ARCH DEV CORP; 发明人 LIAO SHUTSUNG; LIANG TEHMING;
摘要 Disclosed are a novel class of anti-androgenic compounds including saturated and unsaturated fatty acids, their derivatives, and synthetic analogs, according to the following formula: CH3-(CH2)a-(CR1R2CH=CH)b-(CH2)c-COOH, wherein R1 and R2 are each either hydrogen or a halogen; wherein a and c are integers from 0-9; wherein b is an integer from 1-6, provided that 12
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