IMPROVED SPHERICAL ENCODED BEADS |
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| 申请号 | PCT/DK2007000015 | 申请日 | 2007-01-11 | 公开(公告)号 | WO2007079752A3 | 公开(公告)日 | 2008-02-21 |
| 申请人 | NOVO NORDISK AS; CHRISTENSEN SOEREN FLYGENRING; | 发明人 | CHRISTENSEN SOEREN FLYGENRING; | ||||
| 摘要 | The present application discloses a composition comprising a plurality of spherical beads, wherein a radiofrequency chip operating at a frequency of in the range of 2.2-2.7 GHz is embedded within each of said beads and wherein essentially each of said beads is individually identifiable on the basis of radiofrequency identification. Alternatives utilizing a ultrasonic identification chip are also disclosed. The beads are preferably made of polymeric material and can for example be used for the synthesis of e.g. solid-phase chemical libraries. Preferred materials include some that minimise interference in biochemical assays (fouling). The invention also relates to batch and continuous methods of producing such compositions, including emulsion-polymerisation methods. In a further aspect, the present invention relates to an apparatus for analysing radiofrequency-encoded beads. Also provided are methods for detecting and/or analysing and/or sorting beads, as well as methods for processing beads once they have been analysed and/or sorted. | ||||||
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| 说明书全文 | |||||||
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