OPTICALLY ENCODED PARTICLES, SYSTEM AND HIGH-THROUGHPUT SCREENING

申请号 PCT/US2004043001 申请日 2004-12-21 公开(公告)号 WO2005062866A3 公开(公告)日 2006-05-18
申请人 UNIV CALIFORNIA; SAILOR MICHAEL J; MEADE SHAWN O; 发明人 SAILOR MICHAEL J; MEADE SHAWN O;
摘要 The invention concerns a particle (10, 10a) having a code from a library of codes embedded in its physical structure by refractive index changes between different regions of the particle. In preferred embodiments, a thin film possesses porosity that varies in a manner to produce a code detectable in the reflectivity spectrum. An assay detection method uses such a particle and detects a spectral shift in the presence of an analyte. Additional embodiments are disclosed including additional features.
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