首页 / 国际专利分类库 / 化学;冶金 / 生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程 / / 作用于酯键的水解酶 (3.1) / FAD2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks

FAD2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks

申请号 US14019244 申请日 2013-09-05 公开(公告)号 US09963711B2 公开(公告)日 2018-05-08
申请人 Dow AgroSciences LLC; Sangamo BioSciences, Inc.; 发明人 Noel Cogan; John Forster; Matthew Hayden; Tim Sawbridge; German Spangenberg; Steven R. Webb; Manju Gupta; William Michael Ainley; Matthew J. Henry; Jeffrey C. Miller; Dmitry Y. Guschin;
摘要 A method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break in the FAD2 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.
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