COMPOUNDS FOR INDUCING ANTI-TUMOR IMMUNITY AND METHODS THEREOF |
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| 申请号 | US15877864 | 申请日 | 2018-01-23 | 公开(公告)号 | US20180258426A1 | 公开(公告)日 | 2018-09-13 |
| 申请人 | Cornell University; | 发明人 | Juan R. Cubillos-Ruiz; Laurie H. Glimcher; | ||||
| 摘要 | Described herein is a previously unknown function of XBP1 in controlling anti-tumor immunity. It is shown that inhibiting XBP1 in tumor-associated dendritic cells inhibits tumor growth and induces protective anti-tumor immune responses. | ||||||
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| 说明书全文 | |||||||
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