OPEN-TOP MICROFLUIDIC DEVICES AND METHODS FOR SIMULATING A FUNCTION OF A TISSUE

申请号 US15781078 申请日 2016-12-02 公开(公告)号 US20180346859A1 公开(公告)日 2018-12-06
申请人 President and Fellows of Harvard College; 发明人 Antonio Varone; Norman Wen; Daniel Levner; Richard Novak; Lori McPartlin; Donald E. Ingber; Youngjae Choe; Lian Leng; Justin K. Nguyen;
摘要 A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.
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