RESPIRATION DEVICE FOR ANALYSIS OF A RESPONSE TO SHEAR STRESS AND FOREIGN AGENTS ON CELLS

申请号 US15563140 申请日 2016-03-31 公开(公告)号 US20180080925A1 公开(公告)日 2018-03-22
申请人 PRESIDENT AND FELLOWS OF HARVARD COLLEGE; 发明人 Kambez Hajipouran Benam; Richard Novak; Josiah Sliz; Thomas Charles Ferrante; Donald Elliot Ingber; Youngjae Choe;
摘要 A microfluidic system for determining a response of cells comprises one or more fluid pumps. The one or more fluid pumps move a fluid across cells within a microfluidic device. The microfluidic device includes a microchannel at least partially defined by a surface having cells adhered thereto, a first port at one end of the microchannel, and a second port at an opposing end of the microchannel. The one or more fluid pumps move the fluid across the cells in a first direction toward the second port and then move the fluid across the cells in a second direction toward the first port.
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