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序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 用于抑制KSP驱动蛋白活性的化合物 CN200880121479.7 2008-10-16 CN101952255A 2011-01-19 A·M·西迪昆; 戴朝阳; U·F·梅瑟; 杨丽萍; L·D·维沙拉纳; A·R·安吉利斯; G·W·小西普斯; 黄孝华; C·郑
发明涉及下面的式(I)化合物(其中X、R1、R2、R3、R27、R28、p、E、环A和环B如在本文中所定义)。本发明还涉及包含单独的这些化合物以及包含这些化合物和一种或多种附加的治疗剂的组合物(包括药学上可接受的组合物),以及涉及其用于抑制KSP驱动蛋白活性的方法,以及用于治疗与KSP驱动蛋白活性有关的细胞增殖疾病或障碍的方法。
2 Novel epoxy compound having an alicyclic structure, a polymer compound, the resist material, and a patterning process JP2001179593 2001-06-14 JP4178360B2 2008-11-12 武 渡辺; 恒寛 西; 剛 金生; 幸士 長谷川
3 New epoxy compound having alicyclid structure, high- molecular compound, resist material and method for forming pattern JP2001179593 2001-06-14 JP2002371080A 2002-12-26 HASEGAWA KOJI; KANOU TAKESHI; WATANABE TAKESHI; NISHI TSUNEHIRO
PROBLEM TO BE SOLVED: To obtain a sheet material comprising a high-molecular compound as a base resin and useful for microfabrication with electron beams or far ultraviolet radiations because the sheet material is sensitive to high energy rays and has excellent sensitivity, resolution and etching resistance. SOLUTION: The epoxy compound is represented by formula (1) (wherein, W denotes CH2 , O or S; X and Y denote each CR<1> R<2> or C(=O); (k) denotes 0 or 1; R<1> and R<2> denote each H or an alkyl group; and R<1> and R<2> may mutually be bound to form an aliphatic hydrocarbon ring with the carbon atom to which both are bound).
4 Compounds for inhibiting the Ksp kinesin activity JP2010533142 2008-10-16 JP2011503076A 2011-01-27 ララルンティ ディルラクシ ヴィサラナ,; アンジー アール. エンジェルズ,; ジェラルド ダブリュー. ジュニア シップス,; エム. アーシャド シディキ,; チャオヤン ダイ,; クリフ チェン,; シャオフア ファン,; ウマール ファルク マンスール,; リーピン ヤン,
The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, R27, R28, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity.
5 ELECTROACTIVE MATERIALS PCT/US2015056364 2015-10-20 WO2016069321A3 2016-08-18 GAO WEIYING; HOWARD MICHAEL HENRY JR; DIEV VIACHESLAV V; WU WEISHI; MENG HONG
There is disclosed a compound having Formula (I), Formula (II), Formula (III), Formula (VIII), Formula (IX), or Formula (X) The variables are described in detail in the application.
6 BRACHIARIA ENDOPHYTES AND RELATED METHODS PCT/AU2016050887 2016-09-23 WO2017049352A9 2017-05-11 SPANGENBERG GERMAN CARLOS; GUTHRIDGE KATHRYN MICHAELA; MANN ROSS; SAWBRIDGE TIMOTHY IVOR; HETTIARACHCHIGE INOKA KUMARI; EKANAYAKE PIYUMI NIROSHINI; BROHIER NATASHA DENISE; ROCHFORT SIMONE JANE; EDWARDS JACQUELINE
The present invention relates to endophytes, in particular endophytes associated with plants of the Brachiaria-Urochloa species complex, plants infected with the endophytes, products produced by the endophytes, and related methods.
7 새로운 레졸신아렌 기반의 양친매성 화합물 및 이의 활용 KR20160141870 2016-10-28 KR20180046566A 2018-05-09 채필석; 하즈랏후세인
본발명은새롭게개발한레졸신아렌기반의양친매성화합물, 이의제조방법및 이를이용하여막단백질을추출, 용해화, 안정화, 결정화또는분석하는방법에관한것이다. 또한, 이화합물은기존의화합물보다다양한구조와특성을지닌막단백질들을세포막에서효율적으로추출하고이를수용액에서장기간안정적으로보관할수 있고, 이를통해그 기능분석및 구조분석에활용될수 있다. 막단백질구조및 기능분석은신약개발에밀접한관계가있는만큼현 생물학및 화학에서가장관심을갖고있는분야중 하나이다.
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