序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
---|---|---|---|---|---|---|
1 | Process for producing phenothiazine granules | US10312019 | 2001-03-09 | US06983612B2 | 2006-01-10 | Jürgen Beyer; Dietmar Breier; Gunther Effenberger; Michael Roos; Jens Ruppert; Olaf Just; Detlef Wehle |
The invention relates to a method for producing a phenothiazine granulate with a narrow particle size distribution. At least 98% pure phenothiazine in liquid form is pressed through a device provided with boreholes and a frequency is applied to said liquid phenothiazine. The liquid phenothiazine discharged through the boreholes enters a cooling medium having a temperature of between −196 and +120° C. The drops of liquid phenothiazine thus produced are brought to a temperature below melting point and are optionally solidified in another post-cooling area. Optionally, fine-grain particles or coarse-grained particles thus formed can be subsequently removed by appropriate methods. The bulk density of the obtained phenothiazine granulates ranges more particularly from 720–780 kg/m3. | ||||||
2 | Process for the preparation of phenothiazine granules having improved properties | US11324746 | 2006-01-03 | US20060166841A1 | 2006-07-27 | Juergen Beyer; Dietmar Breier; Gunther Effenberger; Michael Roos; Jens Ruppert; Olaf Just; Detlef Wehle |
A process for the preparation of phenothiazine granules having a narrow particle size distribution, phenothiazine having a purity of at least 98% in liquid form being forced through a means provided with holes and a frequency being applied to the liquid phenothiazine and the liquid phenothiazine emerging through the holes entering a cooling medium having a temperature in the range of from −196 to =120° C. so that the liquid phenothiazine drops thus produced are brought to a temperature below the melting point and said drops are, if required, further solidified in a downstream cooling zone. | ||||||
3 | Method for producing a phenothiazine granulate with improved properties | US10312019 | 2003-08-11 | US20040094749A1 | 2004-05-20 | J?uuml;rgen Beyer; Dietmar Breier; Gunther Effenberger; Michael Roos; Jens Ruppert; Olaf Just; Detlef Wehle |
The invention relates to a method for producing a phenothiazine granulate with a narrow particle size distribution. At least 98% pure phenothiazine in liquid form is pressed through a device provided with boreholes and a frequency is applied to said liquid phenothiazine. The liquid phenothiazine discharged through the boreholes enters a cooling medium having a temperature of between null196 and null120null C. The drops of liquid phenothiazine thus produced are brought to a temperature below melting point and are optionally solidified in another post-cooling area. Optionally, fine-grain particles or coarse-grained particles thus formed can be subsequently removed by appropriate methods. The bulk density of the obtained phenothiazine granulates ranges more particularly from 720-780 kg/m3. | ||||||
4 | Method of producing improved phenothiazine granules characteristic | JP2002507797 | 2001-03-09 | JP2004502683A | 2004-01-29 | イエンス、ルッペルト; オラフ、ユスト; ギュンター、エフェンベルガー; ディートマール、ブライアー; デトレフ、ウェーレ; ミヒャエル、ロース; ユルゲン、バイエル |
本発明は、粒子径分布が狭いフェノチアジン顆粒の製造法に関するものである。 少なくとも98%純粋な液体形態のフェノチアジンを、穴を開けた装置を通して圧迫し、該液体フェノチアジンにある周波数を作用させる。 穴を通して排出される液体フェノチアジンは、温度−196℃〜+120℃の冷却媒体に入る。 こうして製造された液体フェノチアジンの滴は融点未満の温度に調節され、所望により別の後冷却区域で凝固される。 所望により、こうして形成された微小粒子または粗い粒子は、続いて適当な方法により除去することができる。 得られるフェノチアジン顆粒のかさ密度は特に720〜780kg/m
3である。
【選択図】なし |
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5 | VERFAHREN ZUR HERSTELLUNG VON PHENOTHIAZIN-GRANULAT MIT VERBESSERTEN EIGENSCHAFTEN | EP01915324.6 | 2001-03-09 | EP1299366A1 | 2003-04-09 | BEYER, Jürgen; BREIER, Dietmar; EFFENBERGER, Gunther; ROOS, Michael; RUPPERT, Jens; JUST, Olaf; WEHLE, Detlef |
The invention relates to a method for producing a phenothiazine granulate with a narrow particle size distribution. At least 98 % pure phenothiazine in liquid form is pressed through a device provided with boreholes and a frequency is applied to said liquid phenothiazine. The liquid phenothiazine discharged through the boreholes enters a cooling medium having a temperature of between-196 and + 120° C. The drops of liquid phenothiazine thus produced are brought to a temperature below melting point and are optionally solidified in another post-cooling area. Optionally, fine-grain particles or coarse-grained particles thus formed can be subsequently removed by appropriate methods. The bulk density of the obtained phenothiazine granulates ranges more particularly from 720 - 780 kg/m3. | ||||||
6 | VERFAHREN ZUR HERSTELLUNG VON PHENOTHIAZIN-GRANULAT MIT VERBESSERTEN EIGENSCHAFTEN | EP01915324.6 | 2001-03-09 | EP1299366B1 | 2006-05-03 | BEYER, Jürgen; BREIER, Dietmar; EFFENBERGER, Gunther; ROOS, Michael; RUPPERT, Jens; JUST, Olaf; WEHLE, Detlef |
The invention relates to a method for producing a phenothiazine granulate with a narrow particle size distribution. At least 98 % pure phenothiazine in liquid form is pressed through a device provided with boreholes and a frequency is applied to said liquid phenothiazine. The liquid phenothiazine discharged through the boreholes enters a cooling medium having a temperature of between-196 and + 120° C. The drops of liquid phenothiazine thus produced are brought to a temperature below melting point and are optionally solidified in another post-cooling area. Optionally, fine-grain particles or coarse-grained particles thus formed can be subsequently removed by appropriate methods. The bulk density of the obtained phenothiazine granulates ranges more particularly from 720 - 780 kg/m3. |