序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
261 Probiotic Strain of Lactobacillus Reuteri Exhibiting Anti-Helicobacter Activity, a Probiotic or Biotherapeutic Product Comprising Said Strain, and the Use Thereof US14913514 2014-08-21 US20160279180A1 2016-09-29 Baltasar Mayo Pérez; Susana Delgado Palacio
The invention relates to a new strain of Lactobacillus reuteri isolated from the human stomach, exhibiting antioxidant and antimicrobial activity, in particular an anti-Helicobacter effect, considerable resistance to the conditions of the gastric ecosystem, and the capacity to adhere to the epithelium. The invention also relates to a probiotic or biotherapeutic product which contains the strain of L. reuteri and is suitable for use in the treatment or prophylaxis of gastric diseases caused by the Helicobacter pylori bacteria, in order to prevent the secondary effects associated with conventional antibiotic treatments.
262 COMPOSITION AND USE OF LACTOBACILLUS REUTERI GMNL-263 IN DECREASING BLOOD LIPID LEVELS US14618188 2015-02-10 US20160095889A1 2016-04-07 YI-HSING CHEN; YA-HUI CHEN; TZU-CHI LOU; TING-YUN SHEN
A use of a Lactobacillus reuteri GMNL-263 in decreasing blood lipid levels is disclosed. Lactobacillus reuteri GMNL-263 (accession No.: CCTCC M 209263) specifically inhibits gene expression related to pro-inflammatory factor and lipid synthesis and promotes gene expression related to cholesterol metabolism. Lactobacillus reuteri GMNL-263 is utilized to produce a composition for decreasing blood lipid levels, thereby achieving the aim of hyperlipidemia treatment.
263 Composition and method of Lactobacillus reuteri GMNL-89 in treating type 2 diabetes US14200162 2014-03-07 US09301983B2 2016-04-05 Hui-Yu Huang; Yi-Hsing Chen; Feng-Ching Hsieh
Present invention features a novel use of Lactobacillus for treating type 2 diabetes, wherein the Lactobacillus is Lactobacillus reuteri GMNL-89 with the deposition numbers of BCRC 910340 and CCTCC M 207154 and comprises of live, dead bacteria or supernatant of the bacterial culture(s) and a pharmaceutically acceptable vehicle. The invention also discloses the efficacies of the indicated Lactobacillus strain including anti-oxidative enzyme activity, anti-inflammation, reduction of blood glucose level, reduction of triglycerides, reduction of total cholesterol, reduction of LDL, increase of HDL and improve insulin utilization.
264 COMPOSITION COMPRISING LACTOBACILLUS AND A CARRIER US14766591 2014-02-05 US20150374764A1 2015-12-31 Karen T. ROBINS; Judith MAZOTTI; Kurt GASSER
Subject of the invention is a food composition comprising Lactobacillus, or a Lactobacillus preparation, which comprises Lactobacillus cell walls, cell wall fragments and/or cell wall constituents, which is capable of aggregating Helicobacter pylori under physiological conditions, and a carrier, wherein the carrier comprises skim milk. Subject of the invention are also methods for producing such food compositions and uses thereof.
265 COMPOSITIONS AND METHODS FOR REDUCED CARBOHYDRATES AND INCREASED ERYTHRITOL IN BEVERAGES US14436588 2013-10-17 US20150320099A1 2015-11-12 Jeroen HUGENHOLTZ; Thilo TRACHOTTA; Martijn BEKKER; Christel CARRIGUES
The present invention provides novel compositions and methods for naturally decreasing carbohydrates and calories, while increasing erythritol, in beverages. The method includes fermenting beverages, such as fruit juices with a microorganism capable of metabolizing sugars into sugar alcohol(s) such as erythritol, to produce a fermented beverage having reduced carbohydrates, and therefore reduced calories, and increased erythritol as compared to an unfermented equivalent beverage.
266 Selection and Use of Lactic Acid Bacteria Preventing Bone Loss in Mammals US14405496 2013-06-04 US20150150917A1 2015-06-04 Eamonn Connolly; Robert Allen Britton, II; Laura Rae McCabe
The present invention comprises a method for selecting lactic acid bacterial strains effective for preventing bone loss in humans and strains that have been selected according to the presented method. The selection method is based on the strain's capability of reestablishing an altered microbial community to normal and/or harboring at least one of four specific SNPs.
267 EXTRUDED NON-REPLICATING PROBIOTIC MICRO-ORGANISMS AND THEIR HEALTH BENEFITS US14541434 2014-11-14 US20150072033A1 2015-03-12 Annick Mercenier; Antoine Wermeille; Audrey Demont; Guenolee Prioult
The present invention generally relates to the field of pro biotic micro-organisms, in particular to the field of non-replicating probiotic micro-organisms. Embodiments of the present invention relate to compositions comprising probiotic microorganisms that were rendered non-replicating by extrusion. Such compositions may be used to treat or prevent disorders that are related to a compromised immune system.
268 Anti-obesity agent and anti-obesity food US13154185 2011-06-06 US08637001B2 2014-01-28 Hidetoshi Morita; Toshio Masaoka; Takehito Suzuki
An anti-obesity agent containing, as an active ingredient, a microorganism which belongs to the species Lactobacillus reuteri and is capable of producing lipases having the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5 or amino acid sequences having deletion, substitution or addition of one or more amino acids in the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5. The anti-obesity agent enables a patient to take a normal meal yet preventing the absorption of a fat into the body which is the primary cause of obesity.
269 Dairy composition with probiotics and anti-microbial system US13709334 2012-12-10 US08617625B2 2013-12-31 Gary Francis Smith; Alice Shen Cha; Zuoxing Zheng; Michael Gerard Roman; Benjamin Emanuel Dias
Dairy compositions are provided having a high pH, of about 4.8 to about 6.2, comprising desirable probiotic cultures as well as an anti-microbial system for inhibiting undesirable pathogenic and/or spoilage microbial growth without significantly reducing the beneficial effect of the probiotic cultures.
270 Complete liquid nutrition for children at the age of 1-10 years comprising probiotics US13319961 2010-05-11 US08603492B2 2013-12-10 Annick Mercenier; Sophie Nutten; Guenolee Prioult
The present invention relates to the field of nutrition for children. In particular, the present invention relates to the nutritional compositions intended for children with an impaired function of the gastro-intestinal tract. One embodiment of the present invention relates to a nutritional composition to be administered to children with an impaired function of the gastrointestinal tract comprising probiotic micro-organisms. The probiotic micro-organisms may be non-replicating, for example bioactive heat treated probiotic micro-organisms.
271 BIFIDOBACTERIUM LONGUM NCC2705 (CNCM I-2618) AND IMMUNE DISORDERS US13901176 2013-05-23 US20130260440A1 2013-10-03 Valerie Petit; Clara Garcia-Rodenas; Monique Julita; Guenolee Prioult; Annick Mercenier; Sophie Nutten
The present invention generally relates to the field of preventing and/or treating inflammatory and infectious disorders, in particular by boosting the endogenous antimicrobial defences. One embodiment of the present invention is the use of B. longum NCC2705 (deposit number CNCM 1-2618) for use in the treatment or prevention of disorders related to the immune system including infections.
272 Increased folate production levels in Lactobacillus fermenting melon juice US12811782 2008-12-05 US08524297B2 2013-09-03 Henderikus Bernardus Albertus Wegkamp; Filipe Branco dos Santos; Eilt Johannes Smid; Jeroen Hugenholtz
The invention relates to the field of food, feed and food supplements comprising high folate levels, whereby the folate is produced by fermentation of Lactobacillus strains on melon fruit extract. Methods for increasing folate production of Lactobacillus strains are also provided.
273 Dairy Composition With Probiotics And Anti-Microbial System US13709334 2012-12-10 US20130164410A1 2013-06-27 Gary Francis Smith; Alice Shen Cha; Zuoxing Zheng; Michael Gerard Roman; Benjamin Emanuel Dias
Dairy compositions are provided having a high pH, of about 4.8 to about 6.2, comprising desirable probiotic cultures as well as an anti-microbial system for inhibiting undesirable pathogenic and/or spoilage microbial growth without significantly reducing the beneficial effect of the probiotic cultures.
274 GROWING UP MILKS CONTAINING PROBIOTIC MICRO-ORGANISMS US13319477 2010-05-11 US20120269789A1 2012-10-25 Annick Mercenier; Sophie Nutten; Guenolee Prioult
The present invention relates to the field of nutrition for infants and young children. In particular, the present invention relates to growing-up milks comprising probiotic micro-organisms to be administered to infants and young children older than 10 months. These probiotic micro-organisms may be non-replicating probiotic micro-organisms such as bioactive heat treated probiotic micro-organisms, for example.
275 ORAL NUTRITIONAL SUPPLEMENT FOR CHILDREN COMPRISING PROBIOTICS US13319943 2010-05-11 US20120189598A1 2012-07-26 Annick Mercenier; Sophie Nutten; Guenolee Prioult
The present invention relates to the field of nutrition for children. In particular, the present invention relates to the field of oral supplements. One embodiment of the present invention relates to the field of oral supplements comprising probiotics and/or bioactive non-replicating probiotics, for example heat treated probiotics.
276 NUTRITIONALLY BALANCED STANDARD TUBE FEEDING FORMULA CONTAINING PROBIOTICS US13319947 2010-05-11 US20120141444A1 2012-06-07 Annick Mercenier; Sophie Nutten; Guenolee Prioult
The present invention relates to the field of enteral nutrition to be administered via tube feeding. In particular, the present invention provides tube feeding formulas for complete nutrition comprising probiotic micro-organisms. Such probiotic micro-organisms may be non-replicating micro-organisms, such as bioactive heat-treated probiotic micro-organisms, for example.
277 INFANT FEEDING FORMULAS COMPRISING PROBIOTIC MICRO-ORGANISMS US13319627 2010-05-11 US20120128726A1 2012-05-24 Annick Mercenier; Sophie Nutten; Guenolee Prioult
The present invention relates to the field of infant nutrition. In particular, the present invention relates to infant feeding formulas comprising probiotic micro-organisms. These probiotic micro-organisms may be non-replicating probiotic micro-organisms such as bioactive heat treated probiotic micro-organisms, for example.
278 BREAKFAST CEREALS CONTAINING PROBIOTIC MICRO ORGANISMS US13319965 2010-05-11 US20120121685A1 2012-05-17 Annick Mercenier; Sophie Nutten; Guenolee Prioult
The present invention relates to the field of nutrition. In particular, the present invention relates to a breakfast cereal composition comprising probiotic micro-organisms. These probiotic micro-organisms may be non-replicating probiotic micro-organisms such as bioactive heat treated probiotic micro-organisms, for example.
279 SPECIALIZED NUTRITIONAL FORMULA FOR ADULT PATIENTS WITH GASTROINTESTINAL INTOLERANCE CONTAINING PROBIOTICS US13319949 2010-05-11 US20120121563A1 2012-05-17 Annick Mercenier; Sophie Nutten; Guenolee Prioult
The present invention relates to the field of nutrition for adults. In particular, the present invention relates to the nutritional compositions intended for adults with an impaired function of the gastro-intestinal tract. One embodiment of the present invention relates to a nutritional composition to be administered to adults with an impaired function of the gastrointestinal tract comprising probiotic micro-organisms. The probiotic micro-organisms may be non-replicating, for example bioactive heat treated probiotic micro-organisms.
280 INFANT AND YOUNG CHILDREN FEEDING FORMULA COMPRISING PROBIOTICS FOR INFANTS AND YOUNG CHILDREN US13319638 2010-05-11 US20120064051A1 2012-03-15 Annick Mercenier; Sophie Nutten; Guenolee Prioult
The present invention relates to the field of infant and young children nutrition. In particular, the present invention relates to infant and young children feeding formulas comprising probiotic micro-organisms to be administered to infants and young children older than 6 months. These probiotic micro-organisms may be non-replicating probiotic micro-organisms such as bioactive heat treated probiotic micro-organisms, for example.
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