| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 在流控芯片中分离珠的方法 | CN201580032596.6 | 2015-06-19 | CN106461653A | 2017-02-22 | 斯蒂格·莫藤·博尔奇; 托尔吉尔·哈姆松德; 约斯泰因·吉尔·霍尔特隆德; 安雅·格利克森 |
| 本发明提供了在包含内部流体回路的流控芯片中分离珠的方法，其中多种反应物通过所述内部流体回路的移动可以通过使用离心力来实现，其中至少一种反应物是珠，所述方法包括以下步骤：在所述流体回路的节段(7、15、18)中至少提供密度为m1的第一组珠(8a)和密度为m2的第二组珠(8b)，所述节段至少包含第一出口(16、13、17)；在所述节段中提供第一液体介质，所述液体介质的密度为d3，使得m1＜d3＜m2；以及施加第一离心力(G)，使得所述第一组珠(8a)和所述第二组珠(8b)在所述节段内沿相反方向移动。 | ||||||
| 2 | 一种中低品味硅藻土选矿用分散剂及其制备方法 | CN201510935461.2 | 2015-12-15 | CN105457761A | 2016-04-06 | 吴照洋; 张志湘 |
| 本发明涉及一种中低品味硅藻土选矿用分散剂及其制备方法，该发明产品由如下原料制成：酒石酸钠、无水乙醇、钛酸酯偶联剂、水玻璃和水，其中酒石酸钠、无水乙醇、钛酸酯偶联剂、水玻璃和水的摩尔比为8:（30~60）:（0.2~0.9）:（0.1~0.3）；本发明制备的中低品味硅藻土选矿用分散剂有效地解决中低品位硅藻土矿的选矿分散性差的难题，显著提高中低品位硅藻土矿的利用程度。 | ||||||
| 3 | 转移珠的方法 | CN201580032664.9 | 2015-06-19 | CN106461654A | 2017-02-22 | 斯蒂格·莫藤·博尔奇; 托尔吉尔·哈姆松德; 约斯泰因·吉尔·霍尔特隆德; 安雅·格利克森 |
| 本发明提供了在包含内部流体回路的流控芯片中转移珠的方法，其中多种反应物通过所述内部流体回路的移动可以通过使用离心力来实现，其中至少一种反应物是珠，所述方法包括以下步骤：在所述流体回路的节段(7、15)中提供密度等于或小于m1的珠(8)，所述节段包含至少第一出口(16、13)；向所述节段提供第一液体介质，所述液体介质的密度为d2，使得d2＞m1；以及施加离心力，使得所述珠在所述离心力的相反方向上移动。 | ||||||
| 4 | 从微粒状药物产品中筛选具有预选粒径粒子的方法 | CN98807489.3 | 1998-07-03 | CN1265045A | 2000-08-30 | T·奥姆维特; B·郝格塞特 |
| 本发明提供一种从微粒状药物产品中筛选具有预选粒径粒子的方法,所述方法包括:(i)得到所述微粒状药物产品在一种流体悬浮介质中的基本均匀的混悬液,该流体悬浮介质与所述微粒状药物不相混溶,其密度也不同于所述产品,(ii)进行粒径筛选过程,以设置最终微粒状产品粒子粒径的有效上限或下限,和(iii)根据需要,进一步进行粒径筛选过程,以制得含有预选粒径粒子的微粒状产品,其中步骤(ii)包括(iv)将所述混悬液沉降一段预定的时间,(v)按预定的体积比将所述混悬液再分离为第一和第二组分,所述第一组分来自混悬液的上层,所述第二组分来自混悬液的下层,(vi)向所述第一组分中进一步加入密度大于药物产品的悬浮介质,或者向所述第二组分中进一步加入密度小于药物产品的悬浮介质,并混合,制得微粒状药物产品在所述悬浮介质中的基本均匀的混悬液,和(vii)重复步骤(iv)至(vi)至少一次,可选地省略步骤(vi)的最后一次重复操作,在重复步骤(vi)时,向第一组分或第二组分中加入流体悬浮介质,其中在步骤(vi)的第一次操作中制得的基本均匀的混悬液分别来自第一组分或第二组分,从而设置了最终微粒状产品粒子粒径的有效下限;或者(viii)将所述混悬液沉降一段预定的时间,(ix)按第二种预定体积比将所述混悬液再分离为第三和第四组分,所述第三组分来自所述混悬液的上层,所述第四组分来自所述混悬液的下层,保留其中所述介质密度小于药物产品的所述第三组分或其中所述介质密度小于药物产品的所述第四组分,从而通过所述第二种预定体积比,设置所保留组分粒子粒径的有效上限。 | ||||||
| 5 | 分析方法 | CN201580032730.2 | 2015-06-19 | CN106461655A | 2017-02-22 | 斯蒂格·莫藤·博尔奇; 托尔吉尔·哈姆松德; 约斯泰因·吉尔·霍尔特隆德; 安雅·格利克森 |
| 本发明提供了分析含有待定性和/或定量测定之分析物的样品的方法，其包括结合步骤和洗涤步骤，其中所述结合步骤包括：使所述分析物与密度为m1的珠相互作用；获得包含密度为m2的可定量珠复合体的堆积珠结构；并且所述洗涤步骤包括：使所述堆积珠分散在密度为d＞m2和m1的液体介质中；以及将所述液体介质与包含所述可定量珠复合体的所述珠分离。 | ||||||
| 6 | 用于密度梯度分离的方法和插入件 | CN201280029951.0 | 2012-05-03 | CN103619484A | 2014-03-05 | S·M·伍德赛德 |
| 本发明描述了一种适合用于密度梯度分离的离心管的插入件。插入件包括元件，所述元件尺寸确定成配合在管内以用于将管分成顶部分和底部分。可选地插入件具有支撑件，所述支撑件从元件延伸或悬挂以用于将元件定位在管内。至少两个开口位于元件上，使得当插入件定位在离心管中时，第一开口相对于第二开口更靠近管的底端。也描述了一种使用离心管的插入件从样本分离靶细胞群的方法。 | ||||||
| 7 | 水化成粒装置 | CN00803491.5 | 2000-02-08 | CN1171666C | 2004-10-20 | 利昂·乌尔维林; 欧内斯特·费伯; 罗伯特·G·戈芬 |
| 一种用于产品的水化成粒装置，它包括一个适于注入粒化水的粒化池(10)和与粒化池分开的沉淀池(12)，以及将水/颗粒的混合物从粒化池(10)引进沉淀池(12)的分配器(26)。沉淀池(12)由几个浓缩池(30)组成，浓缩池悬挂在一个支撑构件上。浓缩池(30)是漏斗形并且伸进一个排管(32)内，排管配有一个闭塞件(33)。沉淀池(12)还有一个周壁(34)，周壁上有至少一个溢流出口(36)。 | ||||||
| 8 | 水化成粒装置 | CN00803491.5 | 2000-02-08 | CN1338974A | 2002-03-06 | 利昂·乌尔维林; 欧内斯特·费伯; 罗伯特·G·戈芬 |
| 一种用于产品的水化成粒装置,它包括一个适于注入粒化水的粒化池(10)和与粒化池分开的沉淀池(12),以及将水/颗粒的混合物从粒化池(10)引进沉淀池(12)的分配器(26)。沉淀池(12)由几个浓缩池(30)组成,浓缩池悬挂在一个支撑构件上。浓缩池(30)是漏斗形并且伸进一个排管(32)内,排管配有一个闭塞件(33)。沉淀池(12)还有一个周壁(34),周壁上有至少一个溢流出口(36)。 | ||||||
| 9 | タンニン含有ポリマーを用いて藻類を凝集させる方法 | JP2017123804 | 2017-06-26 | JP6392416B2 | 2018-09-19 | ウォルタリック,ジェラルド・セシル,ジュニア; ホイット,デイヴィッド; ジュチンスキ,ジョン |
| 10 | Method of separating and use density-specific blood cell | JP50207987 | 1987-03-04 | JP2553606B2 | 1996-11-13 | SAASEKU BORISU; SAASEKU REA |
| Method for the detection of certain diseases and body conditions based upon the response to antigenes associated with the disease or condition tested for by lymphocytes having buoyant densities of 1.0590g/cm<3> to 1.0670g/cm<3> and densities of 1.0690g/cm<3> to 1.0730g/cm<3> in a continuous density gradient solution having an osmolality of 0.315 to 0.320 osm/kg at a temperature of 20 DEG C. The response is indicated by changes in the structure of the cytoplasmic matrix of the cell as measured by intracellular fluorescein fluorescence polarization. The lymphocytes are separated from peripheral blood by centrifugation in a continuous gradient density solution having limiting density gradients which bracket the range of buoyant densities of the lymphocytes to be separated. | ||||||
| 11 | JPH0220297B2 - | JP16283980 | 1980-11-18 | JPH0220297B2 | 1990-05-08 | AKIMOTO HIDETOSHI; KAJI RYUICHI; KOMURO TAKEO; MURANAKA TADASHI; KIKUCHI HIDEO; HISHINUMA TAKAO; NAKAJIMA FUMITO; TERADA HIROSHI |
| 12 | JPS63503164A - | JP50207987 | 1987-03-04 | JPS63503164A | 1988-11-17 | |
| Method for the detection of certain diseases and body conditions based upon the response to antigenes associated with the disease or condition tested for by lymphocytes having buoyant densities of 1.0590g/cm<3> to 1.0670g/cm<3> and densities of 1.0690g/cm<3> to 1.0730g/cm<3> in a continuous density gradient solution having an osmolality of 0.315 to 0.320 osm/kg at a temperature of 20 DEG C. The response is indicated by changes in the structure of the cytoplasmic matrix of the cell as measured by intracellular fluorescein fluorescence polarization. The lymphocytes are separated from peripheral blood by centrifugation in a continuous gradient density solution having limiting density gradients which bracket the range of buoyant densities of the lymphocytes to be separated. | ||||||
| 13 | JPS6143120B2 - | JP8243076 | 1976-07-10 | JPS6143120B2 | 1986-09-25 | FURANKU KOONERYUUSU ROESURAA |
| A solids-liquid mixture, such as waste water, containing biologically degradable material is treated in a circulatory system having alternating upward and downward flow kept in motion by injection of gas such as air. Mixture is diverted from the system into a separating chamber in which solids-enriched mixture is separated by flotation and/or sedimentation. A solids-rich mixture, preferably recycled from the separation chamber, is fed into the system hydrostatically and thereby the concentration of such solids in the system is maintained and/or such solids are transferred from one location to another without mechanical pumping. | ||||||
| 14 | JPS513312B1 - | JP1102572 | 1972-02-01 | JPS513312B1 | 1976-02-02 | |
| 15 | 비드의 이송 방법 | KR1020177001706 | 2015-06-19 | KR1020170020893A | 2017-02-24 | 보르흐,스티그,모르텐; 함순드,토르게이르; 홀트룬드,요스타인,게이르; 귤릭센,아냐 |
| 본발명은적어도하나의반응물이비드(bead)인각종반응물이원심력의사용에의해이동될수도있는내부유체회로를포함하는유체칩중의비드의이송방법을제공하며, 상기방법은: 유체칩의섹션(7, 15) 중에 m1 이하의밀도를갖는비드(8)를제공하는단계로서, 섹션은적어도제 1 출구(16, 13)를포함하는, 단계; 섹션에제 1 액체매체를제공하는단계로서, 액체매체는 d2 > m1이도록밀도 d2를갖는, 단계; 및비드가원심력의반대방향으로이동하도록원심력을가하는단계를포함한다. | ||||||
| 16 | 상이한 물질들을 분류하는 공정, 시스템 및 장치 | KR1020087012274 | 2006-10-24 | KR1020080074900A | 2008-08-13 | 바레리오토마스에이. |
| An automated system for sorting dissimilar materials, and in particular for sorting plastics from other materials and for sorting different types of plastics from one another comprises, depending upon the embodiment, combinations of a sizing mechanism, a friction separation, an air separator, a magnetic separator, a dielectric sensor sortation bed, shaker screening, a ballistic separator, an inductive sensor sortation system and a float/sink tank. The dielectric sensor sortation system may be either analog or digital, depending upon the particular implementation. One or more float/sink tanks can be used, depending upon the embodiment, each with a media of a different specific gravity. The media may be water, or water plus a compound such as calcium chloride. In addition, multiples of the same general type of module can be used for particular configurations. A heavy media system or a sand float process can be used either alternatively or additionally. | ||||||
| 17 | METHOD OF SEPARATING BEADS IN A FLUIDIC CHIP | EP15735866.4 | 2015-06-19 | EP3158334B1 | 2018-10-17 | BORCH, Stig Morten; HAMSUND, Torgeir; HOLTLUND, Jostein Geir; GULLIKSEN, Anja |
| The present invention provides a method of analyzing a sample containing an analyte to be qualitatively and/or quantitatively determined, comprising a binding step and a washing step, wherein the binding step comprises: interacting the analyte with beads having a density m1; obtaining a structure of packed beads comprising quantifiable bead complexes having a density m2; and the washing step comprises: dispersing the packed beads in a liquid medium having a density d>m2 and m1; and separating the liquid medium and the beads comprising the quantifiable bead complexes. | ||||||
| 18 | METHOD OF TRANSFERRING BEADS | EP15730768.7 | 2015-06-19 | EP3158333A1 | 2017-04-26 | BORCH, Stig Morten; HAMSUND, Torgeir; HOLTLUND, Jostein Geir; GULLIKSEN, Anja |
| The present invention provides a method of analyzing a sample containing an analyte to be qualitatively and/or quantitatively determined, comprising a binding step and a washing step, wherein the binding step comprises: interacting the analyte with beads having a density m1; obtaining a structure of packed beads comprising quantifiable bead complexes having a density m2; and the washing step comprises: dispersing the packed beads in a liquid medium having a density d>m2 and m1; and separating the liquid medium and the beads comprising the quantifiable bead complexes. | ||||||
| 19 | POLYMER BLENDS FOR FLOCCULATION | EP14783316.4 | 2014-02-21 | EP2983805A1 | 2016-02-17 | HOLT, Jason |
| Polymer flocculants are described comprising blends of high molecular weight polyethylene oxide and high molecular polyacrylamides. When introduced in desired amounts and with desired molecular weight ranges, excellent flocculation function is found that can be used to reduce polymer consumption to obtain a desired purity of clarified waste water. It has been found that the desirable polymer blends can be effectively added upstream from locations in which polyethylene oxide would generally be added so that the polymer blend can effectively mix with the slime flow to reduce or eliminate the need for excess polymer use to compensate for less effective mixing with the slime flow. Suitable waste treatment systems are described to provide for the delivery of the flocculants in the waste treatment process. | ||||||
| 20 | METHOD AND INSERT FOR DENSITY GRADIENT SEPARATION | EP12779315 | 2012-05-03 | EP2704841A4 | 2014-10-22 | WOODSIDE STEVEN M |
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