序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 Production of Acrylate in Cells US15421495 2017-02-01 US20170218409A1 2017-08-03 Jameson K. Rogers; George M. Church
A method of producing acrylate in vivo in a genetically modified bacteria cell is provided including providing a cell with a first one or more nucleic acids encoding a pathway resulting in the production of 3-hydroxypropionate, providing the cell with a second one or more nucleic acids encoding a truncated pcs enzyme lacking a domain converting acrylyl-CoA to propionyl-CoA, providing the cell with a third one or more nucleic acids encoding acrylyl-CoA hydrolase, wherein the cell expresses the first, second and third one or more nucleic acids and produces acrylate.
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