| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | METHOD FOR ISOMERIZING DOUBLE BONDS | US16032454 | 2018-07-11 | US20180312877A1 | 2018-11-01 | Eleanore T. Wurtzel; Jesús Beltrán |
| A method for isomerizing a double bond is provided. A substrate is exposed to an isomerase enzyme, wherein the isomerase enzyme comprises a redox-regulated ligand switch and heme b cofactor. A reducing agent changes iron (III) to iron (II). The enzyme isomerizes double bonds in the iron (II) state but not in the iron (III) state. In one embodiment, the enzyme is homologous with 15-cis-ζ-carotene isomerase (Z-ISO). | ||||||
| 2 | Method for isomerizing double bonds | US15169894 | 2016-06-01 | US10036042B2 | 2018-07-31 | Eleanore T. Wurtzel; Jesús Beltrán |
| A method for isomerizing a double bond is provided. A substrate is exposed to an isomerase enzyme, wherein the isomerase enzyme comprises a redox-regulated ligand switch and heme b cofactor. A reducing agent is added which changes iron (III) to iron (II). The enzyme isomerizes double bonds in the iron (II) state but not in the iron (III) state. In one embodiment, the enzyme is homologous with 15-cis-ζ-carotene isomerase (Z-ISO). | ||||||
| 3 | METHOD FOR ISOMERIZING DOUBLE BONDS | US15169894 | 2016-06-01 | US20160348133A1 | 2016-12-01 | Eleanore T. Wurtzel; Jesús Beltrán |
| A method for isomerizing a double bond is provided. A substrate is exposed to an isomerase enzyme, wherein the isomerase enzyme comprises a redox-regulated ligand switch and heme b cofactor. A reducing agent is added which changes iron (III) to iron (II). The enzyme isomerizes double bonds in the iron (II) state but not in the iron (III) state. In one embodiment, the enzyme is homologous with 15-cis-ζ-carotene isomerase (Z-ISO). | ||||||
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