| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | Method of preventing transport of a neurotropic virus and identifying agents for achieving same | US10031492 | 2000-07-20 | US06953661B1 | 2005-10-11 | Russell John Diefenbach; Monica Miranda-Saksena; Eve Margaret Diefenbach; David James Holland; Anthony Lawrence Cunningham; Mark Penfold; Patricia Joan Armati |
| A method of preventing transport of a Herpes simplex virus within a neuron, comprising preventing interaction between a structural tegument protein US11 of the virus and a motor protein, Kinesin in the neuron such that virus transport in the neuron is prevented. An antiviral composition is also provided, comprising a compound capable of preventing interaction between a structural tegument protein of a neurotropic virus and a neuron or cell. | ||||||
| 2 | Neurotropic virus transport | JP2001510465 | 2000-07-20 | JP2003504407A | 2003-02-04 | アントニー・ローレンス・カニンガム; イヴ・マーガレット・ディーフェンバック; デイヴィッド・ジェイムズ・ホランド; パトリシア・ジョウン・アーマティ; マーク・ペンフォルド; モニカ・ミランダ−サクセナ; ラッセル・ジョン・ディーフェンバック |
| (57)【要約】 ニューロン又は細胞内への神経向性ウィルスの輸送を妨げる又は減少させる方法であって、該方法は、ニューロン又は細胞へのウィルス輸送を防止又は減少させるように、ウィルスの構造外被蛋白質とニューロン又は細胞中のモーター蛋白質との間の相互作用を変化させる又は妨げることを含むものである方法。 神経向性ウィルスの構造外被蛋白質とニューロン又は細胞中のモーター蛋白質との間の相互作用を変化させる又は妨げることができる化合物を含む抗ウィルス組成物。 | ||||||
| 3 | Neurotropic virus transport | EP07116331.5 | 2000-07-20 | EP1992359A1 | 2008-11-19 | Diefenbach, Russell John; Miranda-Saksena, Monica; Diefenbach, Eve, Margaret; Holland, David, James; Armati, Patricia, Joan; Cunningham, Anthony, Lawrence; Penfold, Mark |
A method of preventing or reducing transport of a neurotropic virus within a neuron, the method comprising altering or preventing interaction between a structural tegument protein of the virus and a motor protein in the neuron such that virus transport in the neuron is prevented or reduced. |
||||||
| 4 | NEUROTROPIC VIRUS TRANSPORT | EP00945443 | 2000-07-20 | EP1202741A4 | 2004-01-14 | DIEFENBACH RUSSELL JOHN; MIRANDA-SAKSENA MONICA; DIEFENBACH EVE MARGARET; HOLLAND DAVID JAMES; ARMATI PATRICIA JOAN; CUNNINGHAM ANTHONY LAWRENCE; PENFOLD MARK |
| 5 | NEUROTROPIC VIRUS TRANSPORT | EP00945443.0 | 2000-07-20 | EP1202741A1 | 2002-05-08 | DIEFENBACH, Russell, John; MIRANDA-SAKSENA, Monica; DIEFENBACH, Eve, Margaret; HOLLAND, David, James; ARMATI, Patricia, Joan; CUNNINGHAM, Anthony, Lawrence; PENFOLD, Mark |
| A method of preventing or reducing transport of a neurotropic virus within a neuron, the method comprising altering or preventing interaction between a structural tegument protein of the virus and a motor protein in the neuron such that virus transport in the neuron is prevented or reduced. An antiviral composition comprising a compound capable of altering or preventing interaction between a structural tegument protein of a neurotropic virus and a motor protein in a neuron or cell. | ||||||
QQ群二维码
意见反馈
意见反馈