| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 一种杀虫晶体蛋白的非受体结合蛋白组合物及其提取方法和应用 | CN201610103013.0 | 2016-02-25 | CN105669842A | 2016-06-15 | 林毅; 刘肖萍; 古宇清; 余小强 |
| 本发明公开了一种杀虫晶体蛋白的非受体结合蛋白组合物及其提取方法和应用，该非受体结合蛋白组合物包括但不局限于微管蛋白、谷胱甘肽合成酶、ATP合成酶、精氨酸激酶、凝集素、胰蛋白酶、翻译延伸因子和细胞色素C氧化酶，且该非受体结合蛋白组合物是通过亲和层析自包含中肠肠腔液的害虫中肠的水溶性物质中提取的，上述亲和层析所用的亲和分子为杀虫晶体蛋白Cry。应用本发明的非受体结合蛋白组合物可在不改变工厂现有产品基础上，提高Cry的杀虫活性，克服害虫对现有产品所产生的抗性问题，以及一些重要害虫对现有产品活性不高的问题。 | ||||||
| 2 | Antibodies to argininosuccinate synthase and related methods | US14794273 | 2015-07-08 | US09938355B2 | 2018-04-10 | Wei He; Yunyun Guo; Bor-Wen Wu |
| Antibodies, and antigen-binding fragments, which specifically bind to argininosuccinate synthase, and related compositions, kits, and methods of use, which are useful as companion diagnostics to identify suitable subjects for arginine deprivation or depletion therapies such as ADI-PEG 20 and other arginine deiminase (ADI) polypeptide-based therapies. | ||||||
| 3 | ANTIBODIES TO ARGININOSUCCINATE SYNTHASE AND RELATED METHODS | US14794273 | 2015-07-08 | US20160009821A1 | 2016-01-14 | Wei He; Yunyun Guo; Bor-Wen Wu |
| Provided are antibodies, and antigen-binding fragments thereof, which specifically bind to argininosuccinate synthase, and related compositions, kits, and methods of use thereof, for instance, as companion diagnostics to identify suitable subjects for arginine deprivation or depletion therapies such as ADI-PEG 20 and other arginine deiminase (ADI) polypeptide-based therapies. | ||||||
| 4 | ANTIBODIES TO ARGININOSUCCINATE SYNTHASE AND RELATED METHODS | EP15819121.3 | 2015-07-08 | EP3166972A1 | 2017-05-17 | HE, Wei; GUO, Yunyun; WU, Bor-Wen |
| Antibodies, and antigen-binding fragments, which specifically bind to argininosuccinate synthase, and related compositions, kits, and methods of use, which are useful as companion diagnostics to identify suitable subjects for arginine deprivation or depletion therapies such as ADI-PEG 20 and other arginine deiminase (ADI) polypeptide-based therapies. | ||||||
| 5 | ANTIBODIES TO ARGININOSUCCINATE SYNTHASE AND RELATED METHODS | EP15819121 | 2015-07-08 | EP3166972A4 | 2018-01-31 | HE WEI; GUO YUNYUN; WU BOR-WEN |
| Antibodies, and antigen-binding fragments, which specifically bind to argininosuccinate synthase, and related compositions, kits, and methods of use, which are useful as companion diagnostics to identify suitable subjects for arginine deprivation or depletion therapies such as ADI-PEG 20 and other arginine deiminase (ADI) polypeptide-based therapies. | ||||||
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