| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | PICHIA PASTORIS LOCI ENCODING ENZYMES IN THE ADENINE BIOSYNTHETIC PATHWAY | US13272543 | 2011-10-13 | US20120100617A1 | 2012-04-26 | Juergen Nett |
| Disclosed are the ADE3, ADE4, ADE5, 7, ADE6, ADE8, ADE12, and ADE13 genes encoding various enzymes in the adenine biosynthesis pathway of Pichia pastoris. The loci in the Pichia pastoris genome encoding these enzymes are useful sites for stable integration of heterologous nucleic acid molecules into the Pichia pastoris genome. The genes or gene fragments encoding the particular enzymes, which may be used as selection markers for constructing recombinant Pichia pastoris. | ||||||
| 2 | Genes and protein sequences useful as drug targets for therapeutic action against protozoa | US10270311 | 2002-10-15 | US20040082048A1 | 2004-04-29 | Nittala Venkata Narasimha Viswanath; Jagannadham Kodam |
| Novel gene and protein sequences useful as drug targets for therapeutic action include at least one enzyme selected from the group consisting of (a) aldolase, (b) lactate dehydrogenase, (c) 3-phosphoglycerate kinase, (d) carbamoyl phosphate synthase, (e) glutamine amido transferase, (f) chitinase, (g) amino acyl synthetase, and (h) trypsin inhibitor (Kunitz protease inhibitor). | ||||||
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