序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR (TALE) - LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) FUSION PROTEINS US14435065 2013-10-11 US20150267176A1 2015-09-24 Jae Keith Joung; Eric M. Mendenhall; Bradley E. Bernstein; Deepak Reyon
Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof.
2 TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR (TALE) - LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) FUSION PROTEINS EP13845212.3 2013-10-11 EP2906602A1 2015-08-19 JOUNG, Jae Keith; MENDENHALL, Eric M.; BERNSTEIN, Bradley E.; REYON, Deepak
Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof.
3 TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR (TALE) - LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) FUSION PROTEINS EP13845212 2013-10-11 EP2906602A4 2016-06-01 JOUNG JAE KEITH; MENDENHALL ERIC M; BERNSTEIN BRADLEY E; REYON DEEPAK
Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof.
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