1 |
Methods of regulating renalase (Monoamime Oxidase C) |
US11602409 |
2006-11-21 |
US20070248585A1 |
2007-10-25 |
Gary Desir; Jianchao Xu |
The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action. |
2 |
METHODS OF REGULATING RENALASE (MONOAMINE OXIDASE C) |
US12946630 |
2010-11-15 |
US20110081421A1 |
2011-04-07 |
GARY DESIR; JIANCHAO XU |
The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action. |
3 |
Methods of treatment with renalase (monoamine oxidase C) |
US11602409 |
2006-11-21 |
US07858084B2 |
2010-12-28 |
Gary Desir; Jianchao Xu |
The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action. |
4 |
Adjustment method of Renaraze (monoamine oxidase c) |
JP2008541423 |
2006-11-21 |
JP2009516693A |
2009-04-23 |
シュ,ジアンチャオ; デジール,ゲイリー,ブイ. |
本発明は、レナラーゼとしても公知であるモノアミンオキシダーゼC(MAO−C)の、治療的タンパク質としてのその活性および不活性形態での使用方法を提供する。 不活性型レナラーゼタンパク質のレナラーゼレベルの低い個体への投与を、必要に応じて身体により活性されることが可能であるタンパク質の適切なプールをこれらの個体に提供するために用いることが可能である。 活性レナラーゼタンパク質は、カテコールアミンレベルの即時の低下が必要である個体へ投与されることが可能である。 レナラーゼの阻害剤は、アドレナリン作用を増強するために用いられ得る。 |
5 |
METHODS OF REGULATING RENALASE (MONOAMINE OXIDASE C) |
EP06844468 |
2006-11-21 |
EP1951291A4 |
2012-04-04 |
DESIR GARY V; XU JIANCHAO |
|
6 |
METHODS OF REGULATING RENALASE (MONOAMINE OXIDASE C) |
EP06844468.6 |
2006-11-21 |
EP1951291A1 |
2008-08-06 |
DESIR, Gary, V.; XU, Jianchao |
The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action. |