1 |
癌症的生物标记 |
CN201280063658.6 |
2012-10-24 |
CN104011543B |
2016-06-15 |
D.T.廷; S.马赫斯瓦兰; D.A.哈伯 |
基于检测存在随体相关基因提高的表达水平来诊断癌症并监控治疗效果的方法。 |
2 |
癌症的生物标记 |
CN201280063658.6 |
2012-10-24 |
CN104011543A |
2014-08-27 |
D.T.廷; S.马赫斯瓦兰; D.A.哈伯 |
基于检测存在随体相关基因提高的表达水平来诊断癌症并监控治疗效果的方法。 |
3 |
Biomarkers of Cancer |
US15496234 |
2017-04-25 |
US20170292942A1 |
2017-10-12 |
David Tsai Ting; Shyamala Maheswaran; Daniel A. Haber |
Methods for diagnosing cancer and monitoring treatment efficacy based on detecting the presence of increased levels of expression of satellite correlated genes. |
4 |
Biomarkers of Cancer |
US14353708 |
2012-10-24 |
US20140287956A1 |
2014-09-25 |
David Tsai Ting; Shyamala Maheswaran; Daniel A. Haber |
Methods for diagnosing cancer and monitoring treatment efficacy based on detecting the presence of increased levels of expression of satellite correlated genes. |
5 |
癌のバイオマーカー |
JP2014538904 |
2012-10-24 |
JP6247218B2 |
2017-12-13 |
ティン,デイヴィッド ツァイ; マヘスワラン,シャマラ; ハーバー,ダニエル エー. |
|
6 |
癌のバイオマーカー |
JP2014538904 |
2012-10-24 |
JP2014532409A |
2014-12-08 |
ツァイ ティン,デイヴィッド; マヘスワラン,シャマラ; エー. ハーバー,ダニエル |
サテライト相関遺伝子の発現レベルの増加の存在を検出することに基づいた、癌を診断するための方法、および処置効力をモニターするための方法。【選択図】図4C |
7 |
BIOMARKERS OF CANCER |
EP12843478 |
2012-10-24 |
EP2771685A4 |
2015-10-21 |
TING DAVID TSAI; MAHESWARAN SHYAMALA; HABER DANIEL A |
Methods for diagnosing cancer and monitoring treatment efficacy based on detecting the presence of increased levels of expression of satellite correlated genes. |
8 |
BIOMARKERS OF CANCER |
EP12843478.4 |
2012-10-24 |
EP2771685A1 |
2014-09-03 |
TING, David Tsai; MAHESWARAN, Shyamala; HABER, Daniel A. |
Methods for diagnosing cancer and monitoring treatment efficacy based on detecting the presence of increased levels of expression of satellite correlated genes. |
9 |
BIOMARKERS OF CANCER |
EP12843478.4 |
2012-10-24 |
EP2771685B1 |
2018-06-13 |
TING, David Tsai; MAHESWARAN, Shyamala; HABER, Daniel A. |
Methods for diagnosing cancer and monitoring treatment efficacy based on detecting the presence of increased levels of expression of satellite correlated genes. |
10 |
멜라노코르틴 수용체 MC4R 돌연변이체 |
KR1020020021425 |
2002-04-19 |
KR1020030083051A |
2003-10-30 |
백자현 |
PURPOSE: A mutant of melanocortin 4-receptor(MC4-R) is provided. The MC4-R mutant has improved activity, so that it can be useful for screening the corpulence treating agents or weight decrease treating agents. CONSTITUTION: A mutant of melanocortin 4-receptor(MC4-R) is prepared by substitution alanine for arginine at position 220 of the amino acid sequence of melanocortin 4-receptor(MC4-R), or threonine at position 232 of the amino acid sequence of melanocortin 4-receptor(MC4-R). A gene encoding the mutant of melanocortin 4-receptor(MC4-R) is provided. A recombinant plasmid containing the melanocortin 4-receptor(MC4-R) mutant gene is provided. A process for preparing the mutant of melanocortin 4-receptor(MC4-R) comprises the steps of: (a) inserting the gene encoding the melanocortin 4-receptor(MC4-R) mutant into a vector containing one or more expression control sequence which is operatively linked to the melanocortin 4-receptor(MC4-R) mutant gene and regulates its expression; (b) transforming a host with the recombinant vector; (c) culturing the transformant in an appropriate medium. |