最新美国发明专利第2018-11-20期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US10132051B2	Hybrid energy plant The invention pertains to energy production by capturing simultaneously water potential (surface height differences due to waves) and kinetic (flow of water due to e.g. waves, tide or streams) energy. The plant can have tidal compensation (2, 3, 22, 23) to avoid energy flux streaming over the plant in high tide, and directional stabilizing arrangement to turn it automatically parallel to wave crests. Surfaces capturing energy from flow have optimized movements to follow speed of water in different depths. Also energy conservation to filter output ripple can be arranged with twin-phase fluid accumulators (51, 55).
US10132049B2	Integrated ballast mat A protective coating system for a railway structure having a waterproof membrane and a ballast mat. The waterproof membrane is disposed on the railway structure. The ballast mat further has a ballast protection coating and a sealing layer. The ballast protection coating is a rubber compound and is disposed on the waterproof membrane. The sealing layer is disposed on the ballast protection layer.
US10132048B1	Non-stick, asphalt-resistive tool and associated use thereof A hand tool includes an elongated handle suitably sized and shaped for handling HMA, and an implement attached to a distal end of the elongated handle. Such an implement includes: a non-stick, asphalt-resistant top layer, and a metal core directly attached to the non-stick, asphalt-resistant top layer, and a non-stick, asphalt-resistant bottom layer directly attached to the metal core. Notably, the metal core is intercalated between the non-stick, asphalt-resistant top layer and the non-stick, asphalt-resistant bottom layer. Advantageously, each of the non-stick, asphalt-resistant top layer and the non-stick, asphalt-resistant bottom layer prohibits hot mix asphalt from adhering onto the implement.
US10132045B2	Traction assist device A traction assist device for mobilizing vehicles stuck in surfaces such as snow and ice includes a panel that has a top face, which is coarse. The panel is flexible, such that the panel is manipulable from an extended configuration into a rolled configuration. A plurality of grasps is coupled to and extends transversely from a bottom face of the panel. The grasps are configured to penetrate into surfaces, such as snow and ice, when the panel is positioned on the surface and a tire of a vehicle is positioned on the top face of the panel. The grasps retain the panel in a fixed position. The top face of the panel is configured to grip the tire, such that traction is supplied of the vehicle.
US10132042B2	Fibrous structures A fibrous structure is disclosed. The fibrous structure exhibits a plurality of discrete knuckles arranged in a pattern of repeat units. The repeat units can include a plurality of rows arranged orthogonally in an X-Y plane, each row having a portion of the discrete knuckles, and each discrete knuckle separated from adjacent discrete knuckles in a row by a distance. Each of the discrete knuckles within the repeat unit can have substantially the same shape and size; and wherein the distance between at least two adjacent discrete knuckles in each row are non-uniform such that the repeat unit exhibits varying pillow width distances along the rows in both the X and Y axes.
US10132040B2	Use of nanocrystaline cellulose and polymer grafted nanocrystaline cellulose for increasing retention in papermaking process Methods and compositions for improving the characteristics of paper substrates are disclosed. The methods involve adding to a paper substrate an NCC-polymer. NCC-polymers have unique chemical properties which result in improvements in wet strength, dry strength and drainage retention properties of the paper substrates.
US10132032B2	Imitation leather and method for producing same An imitation leather including a three-dimensional textile supporting material and a PVC-based covering that is applied to one side of the supporting material and includes three successively applied layers. The first layer of which is applied directly to the supporting material without an adhesion-promoting glue layer, the second layer of which is embodied as an intermediate layer and applied directly to the first layer and the third layer of which serves as a top layer and is applied directly to the second layer. This invention also discloses a method for producing such an imitation leather and an interior component of a motor vehicle having a visible surface that is composed of such an imitation leather.
US10132028B2	Method for manufacturing fabric Provided is a method for manufacturing a fabric having excellent stain resistance and flame retardancy. The method of manufacturing a fabric of the present invention includes the steps of (a) immersing a polyester fabric in a treatment liquid containing a first fluorine-based water-and-oil repellent agent to incorporate the treatment liquid thereinto, followed by drying the fabric; (b) coating one surface of the fabric with a coating composition containing a second fluorine-based water-and-oil repellent agent and a flame retardant; and (c) cleaning the fabric having the coating layer formed thereon with hot water of 65° C. to 90° C.
US10132027B2	Facilitating the assembly of goods by temporarily altering attributes of flexible component materials The invention aims to improve the manufacture of flexible goods, such as garments, through the temporary modification of the physical properties of the components to be assembled, facilitating their handling and manipulation later on in the manufacturing process. Attributes that can be affected by this process are the stiffness of the material, the presence of mechanical or physical markings, the density of the material, the air or fluid permeability of the material, the responsiveness of the material to magnetic fields, or the adhesive nature of the material.
US10132024B2	Clothes treating apparatus A clothes treating apparatus includes a reception unit for receiving clothes, a discharge duct for guiding air coming from an interior of the reception unit to the outside, a filter unit including a frame that is detachably inserted into the discharge duct and a filter provided in the for filtering air, and an attachment unit to detachably couple the filter unit to the discharge duct. The attachment unit includes a body provided in the frame and configured to rotate to allow coupling between the filter unit and the discharge duct, and a coupling part located at one side of the body for selectively coupling to the discharge duct through a through hole in the frame. The body defines a body through hole passing through the body, the body through hole being configured to prevent foreign substances from remaining.
US10132023B2	Household cleaning appliance with a dispensing system operable between a single use dispensing system and a bulk dispensing system In a household cleaning appliance configured to execute a cleaning cycle on an article, having a non-bulk dispensing system that stores a single dose of treating chemistry that the dispensing system dispenses to the treating chamber in total as part of the execution of the cleaning cycle, the method includes adding bulk dispensing functionality to the non-bulk dispensing system for operating the dispensing system as a bulk dispensing system.
US10132022B2	Washing machine appliance with a Venturi pump A washing machine appliance has a dispensing assembly with a supply conduit, a unitary manifold body and a water valve. The unitary manifold body defines a Venturi pump. The supply conduit extends between a reservoir and the Venturi pump such that the Venturi pump draws fluid additive from the reservoir to the Venturi pump when the water valve is open and motive liquid flows through the Venturi pump. The Venturi pump is disposed between an inlet and an outlet of the unitary manifold body within the unitary manifold body.
US10132021B2	Laundry treating appliance door assembly comprising a plastic fishbowl A laundry treating appliance door assembly comprises a plastic fishbowl. Typically, laundry treating appliances, such as dryers, have door assemblies comprising glass fishbowls. Utilizing plastic enables a fishbowl to have a sharper radius of curvature than that of a glass fishbowl due to manufacturing constraints of glass. A shaper radius of curvature allows for greater capacity in the treating chamber in a laundry treating appliance.
US10132020B2	Apparatus for the thermal treatment of a textile web An apparatus for a thermal treatment of a textile web includes at least one drum with a perforated casing surface around which a material web can be at least partially wrapped, at least one connecting element, and a patterning shell with a plurality of openings separated by ridges fitted onto the casing of the drum. The patterning shell includes at least two segments detachably connected with aid of the at least one connecting element. The at least one connecting element is arranged on or integrated into a ridge.
US10132019B2	Floor covering with universal backing and methods of making and recycling A dimensionally stable universal floor covering includes a tufted textile having stitches and a reinforcement layer operatively connected to the stitches to provide dimensional stability for the entire floor covering. The reinforcement layer is made of fibers and adhesive that are formed into a reinforcement layer of laminated fibers that is operatively connected to the stitches and/or the fibers and adhesive are formed into a layer of fibers and adhesive that is contained within the stitches. The fibers and adhesive are mixed and then moved by an applicator toward the stitches. A curved slip path is formed on a curved portion of the applicator to improve the movement of the fibers and adhesive toward the stitches. A removable tip portion on the end of the curved portion of the applicator improves the penetration of the adhesive and provides compression of the fibers towards the ends of the stitches. A releasable adhesive cover system is provided to cover the layer of fibers for providing additional strength and stability and for providing a releasable attachment of the universal floor covering to a supporting surface.
US10132017B1	Fish hook tying tool The fish hook tying tool provides a rotating fish hook holder for a fish hook, and an adjacently mounted cutter for a fishing line, thus providing a combined tool for assisting a fisherman in tying fishing line to a fish hook and the trimming the knot after tying the fishing line. The fish hook tying tool includes a hollow housing having opposed front and rear walls, the front wall having an arcuate slot defined therein. In use, the user slides a lug along a path defined by the arcuate slot to drive rotation of a drive gear mounted within the hollow housing. Manual rotation of the drive gear drives a pinion to rotate, which, in turn, selectively drives a coaxially mounted fish hook holder to rotate with the shank and eye of the fish hook extending away from the tool. An attached clamp secures the tool to a support.
US10132015B2	Non-kinking wrappable knit sleeve and method of construction thereof A warp knit textile sleeve is provided. The sleeve has an elongate, wrappable wall extending along a longitudinal axis between opposite ends. The wall has opposite free edges extending lengthwise along the longitudinal axis between the opposite ends. The wall is knit from at least one warp yarn extending lengthwise between the opposite ends and a plurality of weft yarns extending circumferentially between the opposite free edges. The weft yarns form a plurality of discrete, annular bands alternating in adjacent relation along the longitudinal axis. The weft yarn of one of the adjacent bands has a first diameter and the weft yarn of the other of the adjacent bands has a second diameter, wherein the first diameter is less than the second diameter.
US10132014B2	Woven fabric In a woven fabric woven from first constituent yarns as one of warps and wefts and second constituent yarns as the other, a part of the first constituent yarns are 2 to 15 side emission type optical fibers woven in juxtaposition, and, when the number of the side emission type optical fibers is 3 or more, a twist-preventing yarn having a diameter smaller than that of the side emission type optical fibers is interposed between the one or two side emission type optical fibers and the one or two side emission type optical fibers.
US10132005B2	Method of spinning fibres or extrusion, and the products obtained The invention relates to a continuous, scalable and parallelizable method for preparing strong and stiff fibers (filaments) or films. The fiber or film is prepared by utilizing hydrodynamically induced alignment of the constituents of a dispersion in combination with surface-charge controlled gel transition to produce fibers with a high degree of alignment of the constituents (polymer(s), fibrils etc). The invention also relates to the fibers or films so formed.
US10132003B2	Heating modulators to improve epi uniformity tuning Embodiments disclosed herein generally related to a processing chamber, and more specifically a heat modulator assembly for use in a processing chamber. The heat modulator assembly includes a heat modulator housing and a plurality of heat modulators. The heat modulator housing includes a housing member defining a housing plane, a sidewall, and an annular extension. The sidewall extends perpendicular to the housing plane. The annular extension extends outward from the sidewall. The plurality of heat modulators is positioned in the housing member.
US10132000B2	Diamond substrate and diamond substrate manufacturing method A diamond substrate is formed of diamond single crystals by preparing a base substrate; forming plural pillar-shaped diamonds formed of diamond single crystals on one side of the base substrate; causing a diamond single crystal to grow from a tip of each pillar-shaped diamond and coalescing the diamond single crystals growing from the tips of the pillar-shaped diamonds to form a diamond substrate layer; separating the diamond substrate layer from the base substrate; and manufacturing a diamond substrate from the diamond substrate layer, a shape in an in-plane direction of the diamond substrate is a circular shape or a circular shape having an orientation flat plane formed therein and has a diameter of two inches or more.
US10131995B2	Preparation method of low-pH controlled-release intelligent corrosion inhibitor This disclosure relates to a preparation method of a low-pH controlled-release intelligent corrosion inhibitor. The low-pH controlled-release intelligent corrosion inhibitor comprises a hydrogel with low pH responsiveness and a corrosion inhibiting substance having the capacity of corrosion inhibition. That is, a corrosion inhibiting substance is wrapped in a low-pH sensitive hydrogel. The swelling degree of the pH sensitive hydrogel may be changed according to the amounts of monomers and crosslinking agents so as to control the releasing speed of the corrosion inhibiting substance. By the soaking experiment and the measurements of electrochemical polarization curves and alternating impedance spectra, the sensitive and long-lasting features of the low-pH controlled-release intelligent corrosion inhibitor are indicated. Therefore, the advantageous effects of this disclosure lies in that: 1) the system enables the releasing speed of the corrosion inhibiting substance to be controlled by pH; 2) the system enables long-lasting effect and high corrosion inhibition efficiency of the corrosion inhibiting substance; and 3) the system has broad applicability.
US10131992B2	Substrate processing apparatus, method of controlling substrate processing apparatus, method of maintaining substrate processing apparatus, and recording medium A substrate processing apparatus includes: an operation unit, which is provided with a storage unit that stores a plurality of recipes including a recipe for processing a member that constitutes the inside of a reactor in which substrate processing is performed, and a recipe for processing an exhaust pipe through which a gas released from the inside of the reactor flows, the operation unit further being provided with a display unit that displays a setting condition for executing the recipes on an operation screen; and a control unit that executes the recipe that meets the setting condition. The operation unit includes a recipe control unit, which controls, based on the setting condition, execution of the recipe for processing the member constituting the inside of the reactor in which the substrate processing is performed, and the recipe for processing the exhaust pipe, among the recipes stored in the storage unit.
US10131987B2	Raw material for chemical deposition including organoruthenium compound, and chemical deposition method using the raw material for chemical deposition The invention provides a raw material for chemical deposition having properties required for a CVD compound, that is, which has a high vapor pressure, can be formed into a film at low temperatures (about 250° C. or less), and also has moderate thermal stability. The invention relates to a raw material for chemical deposition, for producing a ruthenium thin film or a ruthenium compound thin film by a chemical deposition method, the raw material for chemical deposition including an organoruthenium compound represented by the following formula, in which a cyclohexadienyl group or a derivative thereof and a pentadienyl group or a derivative thereof are coordinated to ruthenium: wherein the substituents R1 to R12 are each independently a hydrogen atom, a linear or cyclic hydrocarbon, an amine, an imine, an ether, a ketone, or an ester, and the substituents R1 to R12 each have 6 or less carbon atoms.
US10131978B2	Iron-chromium-molybdenum-based thermal spray powder and method of making of the same One embodiment provides a composition, comprising: a powder composition comprising alloy that is at least partially amorphous, the alloy comprising chromium, molybdenum, carbon, boron, and iron. One embodiment provides a method of forming a coating, comprising: providing a substrate; and disposing onto the substrate a coating, comprising: powder composition comprising an alloy that is at least partially amorphous, the alloy comprising chromium, molybdenum, carbon, boron, and iron.
US10131977B2	Ferritic stainless steel sheet having excellent brazability, heat exchanger, ferritic stainless steel sheet for heat exchangers, ferritic stainless steel, ferritic stainless steel for members of fuel supply systems, and member of fuel supply system One aspect of this ferritic stainless steel sheet contains, by mass %, C: 0.03% or less, N: 0.05% or less, Si: 1% or less, Mn: 1.2% or less, Cr: 14% or more and 28% or less, Nb: 8(C +N) or more and 0.8% or less, and Al: 0.1% or less, with a balance being Fe and inevitable impurities, in which a film satisfying Expression 1 is formed in a surface thereof. Expression 1 is df×Crf+5(Sif+3Alf)≤2.0. In Expression 1, df represents a thickness (nm) of the film, Crf represents a Cr cationic fraction in the film, Sif represents a Si cationic fraction in the film, and Alf represents an Al cationic fraction in the film.
US10131971B2	High strength aluminum alloy sheet for anodic oxide coated material and method of producing same and high strength anodic oxide aluminum alloy sheet An aluminum alloy sheet which is high in strength and excellent in heat conductivity, and which can be given an anodic oxide coating with a white color and a suitable yellowishness is provided. An aluminum alloy ingot containing Mg: 0.80 to 1.8 mass %, Fe: 0.05 to 0.30 mass %, Si: 0.20 mass % or less, Cu: 0.03 to 0.15 mass %, Mn: 0.05 to 0.20 mass %, and Cr: 0.05 to 0.15 mass %, restricts Zn to less than 0.15 mass %, and balance of Al and unavoidable impurities is treated by holding it at 560 to 620° C. for 1 to 5 hours, then hot rolled and, either through or not through process annealing, and cold rolled by a final cold rolling reduction of 15 to 95% to obtain an aluminum alloy sheet which has a 0.2% yield strength of 180 MPa or more and a conductivity of 40 (IACS %) or more.
US10131968B2	Recovery of lithium from silicate minerals A process is disclosed for recovering lithium from a lithium-containing silicate mineral. The process comprises mixing the silicate mineral with nitric acid. The process also comprises subjecting the mixture to a leaching process having conditions such that lithium values in the silicate mineral are leached into an aqueous phase as lithium nitrate. The leaching process conditions may be controlled such that non-lithium values in the silicate mineral tend not to be leached into the aqueous phase.
US10131967B1	Scrap submergence walled well A scrap submergence device having an open top chamber including walls constructed of a heat resistant material is provided. The chamber includes an inlet in the side wall of the chamber for receiving molten metal, an outlet in the side wall of said chamber, and an interior wall extending from the base wall. The interior wall has a height lower than a height of the at least one side wall. The inlet is disposed on a first side of the interior wall and the outlet is disposed on a second side of the interior wall.
US10131960B2	Genetically encoded fluorescent sensors for detecting intracellular signalling through diacylglycerol pathways Described herein are novel fluorescent sensors for Diacyl Glycerol (DAG) and phosphatidylinositol 4,5-bisphosphate (PIP2) that are based on circularly permuted fluorescent proteins. These sensors use less visible spectrum than FRET-based sensors, produce robust changes in fluorescence, and can be combined with one another, or with other sensors, in a multiplex assay on standard fluorescent plate readers or live cell imaging systems.
US10131959B2	Diagnostic methods and markers for bacterial vaginosis A method of diagnosing bacterial vaginosis in a woman, which involves determining an amount of each of more than one BV-associated bacterium in a vaginal sample obtained from the female and assessing a BV status of the female based on the amount of each of the more than one BV-associated bacterium in the sample.
US10131958B1	Massively parallel single cell analysis The disclosure provides for methods, compositions, and kits for multiplex nucleic acid analysis of single cells. The methods, compositions and systems may be used for massively parallel single cell sequencing. The methods, compositions and systems may be used to analyze thousands of cells concurrently. The thousands of cells may comprise a mixed population of cells (e.g., cells of different types or subtypes, different sizes).
US10131957B2	Breast cancer biomarkers and methods of using same The present invention provides breast cancer markers based on RECQL mutations, and related methods, uses, agents, and kits. The invention includes methods for determining the susceptibility of a subject to developing breast cancer, and methods for detecting, diagnosing, treating, and predicting responses to treatment for breast cancer.
US10131956B2	Marker used for detection of colon cancer, and application thereof The present invention provides a marker used for detecting colon cancer, and also provides application of said marker in the detection of colon cancer, as well as an associated kit and detection method.
US10131955B2	Methods for detecting genetic and phenotypic biomarkers of urothelial carcinoma and treatment thereof New methods for identifying patents with hematuria who are at low risk of having urothelial cancer (UC) include combining selected phenotypic variables with levels of genotypic expression into a new metric, the “G+P INDEX.” The G+P INDEX combines age, sex, smoking history, presence of hematuria, and frequency of hematuria with genotypic expression of the genetic markers, MDK, CDC2, HOXA13, IGFBP5, and optionally IL8Rb, then determining of the G+P INDEX value obtained for a patient is within one of three groups, either: (1) at High Risk of UC, (2) at Risk of UC, or (3) at Low Risk of UC. For groups 1 and 2, further clinical and laboratory work up is indicated, and patients in group 3 are monitored periodically to determine the need for further clinical workup. Using the G+P INDEX can save substantial time, effort, and funds by avoiding unnecessary medical diagnostic procedures for patients at Low Risk of UC.
US10131954B2	Methods for detection and quantification of EGFRvIII in the peripheral blood of GBM patients Methods and kits for detection and quantification of EGFRvIII in the peripheral blood for monitoring the therapy of a GBM patients.
US10131951B2	Assay systems for genetic analysis The present invention provides assay systems and methods for detection of copy number variation at one or more loci and polymorphism detection at one or more loci in a mixed sample from an individual.
US10131950B2	Method to predict heritable canine non-contact cruciate ligament rupture Method and kits for diagnosing propensity to non-contact cranial cruciate ligament rupture (CCLR) in a dog are described. The method includes isolating genomic DNA from a dog and then analyzing the genomic DNA from step for a single nucleotide polymorphism occurring in selected loci that have been determined to be associated with the CCLR phenotype via a genome-wide association study.
US10131949B2	Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
US10131947B2	Noninvasive detection of fetal aneuploidy in egg donor pregnancies The present invention provides assay systems and methods for determining the percent fetal contribution of cell-free DNA in a maternal sample from a pregnant female with an egg donor pregnancy. Further provided, are assay systems and methods for determining a statistical likelihood of the presence or absence of a fetal aneuploidy in a maternal sample using a determined percent fetal cell-free DNA in the sample.
US10131946B1	Method for identifying agents regulating lipofilling activity A method is provided for characterizing a lipofilling agent causing increased lipofilling activity in adipose tissue from a target body area. Such a method can include obtaining a plurality of distinct preadipocyte cultures taken from a plurality of distinct body areas of an individual, exposing the plurality of distinct preadipocyte cultures to a plurality of potential lipofilling agents, culturing the plurality of distinct preadipocyte cultures through differentiation to form a plurality of distinct adipocyte cultures, measuring a degree of lipofilling activity of adipocytes from each of the plurality of distinct adipocyte cultures, and quantifying the measured lipofilling activity across the plurality of distinct adipocyte cultures to identify a lipofilling agent causing increased lipofilling activity in adipose tissue from the target body area as compared to adipose tissue in the non-target body area.
US10131937B2	Assay systems for genetic analysis The present invention provides assays systems and methods for detection of chromosomal abnormalities and status of single loci associated with monogenic or polygenic traits in a sample containing nucleic acids from a maternal and a fetal source.
US10131935B2	Method for parallel isolation of viral nucleic acids Parallel isolation of a double-stranded nucleic acid and a single-stranded nucleic acid is possible from a sample that contains these acids, without separating the acids, by mixing the sample with a lysis buffer having high salt concentration or low salt concentration, or having a proteolytic enzyme. The sample that contains nucleic acid before its lysis, or the sample that has already been lysed or homogenized, is adjusted with a binding buffer in such a manner that the total nucleic acid is adsorbed onto a solid carrier. The binding buffer contains at least one non-ionic detergent in a high concentration. With the exception of the detergent, the sample contains no other non-acidic organic component miscible in water. The carrier with the adsorbed total nucleic acid is removed. The adsorbed total nucleic acid is washed and eluted.
US10131934B2	Thermal reaction device and method for using the same A method for carrying out nucleic acid amplification reactions using a microfluidic device is described. Amplification primers and other amplification reagents are deposited at a plurality of reaction sites in the device, a sample solution containing amplifiable polynucleotides is introduced into the reaction sites, and amplification is carried out.
US10131929B2	Enzymatically produced cellulose Enzymatic reactions are disclosed herein comprising water, glucose-1-phosphate, cellodextrin, and at least one cellodextrin phosphorylase enzyme comprising an amino acid sequence that is at least 90% identical to SEQ ID NO:2 or SEQ ID NO:6. These reactions produce a low molecular weight, insoluble cellulose with enhanced features.
US10131928B2	Inositol biotransformation Disclosed is a method of preparing pure or substantially pure D-myo-inositol-3-phosphate from glucose-6-phosphate and/or fructose-6-phosphate. The method may also be applied to protected and/or derivative forms of glucose-6-phosphate and/or fructose-6-phosphate so as to form protected/derivative forms of D-myo-inositol-3-phosphate, for use in further chemical reactions. The enzyme D-myo-inositol-3-phosphate synthase (INO1) is contacted with the glucose-6-phosphate and/or fructose-6-phosphate to generate labeled or unlabeled, protected or unprotected D-myo-inositol-3-phosphate, which may be further reacted and/or purified.
US10131927B2	Method for obtaining 1-kestose The present invention discloses an industrial scale method to obtain 1-kestose by the use of a recombinant fructosyltransferase (FTF), isolated from Festuca arundinacea, expressed constitutively in a non-saccharolytic yeast. In this invention, the recombinant FTF type sucrose:sucrose 1-fructosyltransferase (1-SSTrec) is produced constitutively, stable and at high yield, both in the culture supernatant and in intact cells of the host Pichia pastoris. Hence, the invention additionally provides a method for 1-SST production at industrial scale. The recombinant enzyme is then used for mass production of short-chain fructooligosaccharides (FOS), specifically 1-kestose, from sucrose. The method of the present invention establishes conditions that allow conversion rates where the synthesized FOS constitute above 55% (w/w) of the total sugars in the reaction mixture and the 1-kestose content reaches values higher than 90% (w/w) of the total FOS fraction.
US10131926B2	Transaminase and uses thereof A transaminase and a use thereof are provided. The transaminase has the amino acid sequences as shown in SEQ ID NO: 2 or 4, or has at least 80% identity to the amino acid sequences as shown in SEQ ID NO: 2 or 4, or has amino acid sequences which are obtained by the substitution, deletion or addition of one or more amino acids and have an the activity of an omega-transaminase with high stereoselective R-configuration catalytic activity, wherein the high stereoselective refers to the content of one of the stereoisomers being at least about 1.1 times that of the other.
US10131923B2	Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; d) whereby less than 7.5 mg enzyme composition/g glucan (on dry matter and enzyme as protein) or less than 3.0 mg enzyme composition/g feedstock (on dry matter and enzyme as protein) is used; and e) fermentation of the hydrolyzed ligno-cellulosic material to produce a fermentation product; and f) optionally recovery of a fermentation product; wherein before and/or during the enzymatic hydrolysis oxygen is added to the ligno-cellulosic material.
US10131922B2	Increase production of isoprenoids in saccharomyces cerevisiae by carotenoid optimization and screening The invention is for an increased isoprenoid production by carotenoid optimization in an expression system and the carotegenic gene for optimization may be geranylgeranyl diphosphate synthase (GGPPS), phytoene synthase (PSY1), conserved CRTI or mutated CRT1A393T, BT1 of S. cerevisae. The carotogenic gene from red yeast which includes Rhodosporidium spp. Rhodotorula spp, Sporidiobolus spp., Leucosporidium spp., Sporobolomyes spp. is selected.
US10131920B2	Nucleic acid molecules There is provided inter alia a DNA construct which comprises a tRNApyl coding sequence and a RNA polymerase III promoter sequence which is capable of acting to express functional tRNApyl sufficiently to support nonsense suppression in a eukaryotic expression system.
US10131916B2	Regulatory element for heterologous protein production in the fruiting body of filamentous fungi The present invention provides compositions and methods for regulating expression of nucleotide sequences in fungi. Compositions are novel nucleotide sequences for a tissue preferred promoter isolated from the Agaricus bisporus lectin gene. The sequences drive expression preferentially to fruit body tissue. A method for expressing a nucleotide sequence in fungi using the regulatory sequences disclosed herein is provided. The method comprises transforming a fungal cell to comprise a nucleotide sequence operably linked to one or more of the regulatory sequences of the present invention and regenerating a stably transformed fungus from the transformed cell.
US10131913B2	Purification process of nascent DNA A method for initiating the replication of a deoxyribonucleic acid molecule includes inserting into the DNA at least one nucleic acid molecule representing a multicellular DNA replication origin. The replication origin contains at least nine nucleotides and contains at least three uninterrupted origin repeating elements (ORE), each ORE having the sequence N3GN4, wherein N3 is T or G and N4 is G or C. The method can confer autonomous replication properties to a non-self-replicating DNA molecule. A process for preparing a vector for use in said methods is also presented.
US10131912B2	Extended dicer substrate agents and methods for the specific inhibition of gene expression The invention provides compositions and methods for reducing expression of a target gene in a cell, involving contacting a cell with an isolated double stranded nucleic acid (dsNA) in an amount effective to reduce expression of a target gene in a cell. The dsNAs of the invention possess a pattern of deoxyribonucleotides (in most embodiments, the pattern comprises at least one deoxyribonucleotide-deoxyribonucleotide base pair) designed to direct the site of Dicer enzyme cleavage within the dsNA molecule. Deoxyribonucleotides of the dsNA molecules of the invention are located within a region of the dsNA that can be excised via Dicer cleavage to generate an active siRNA agent that no longer contains the deoxyribonucleotide pattern (e.g., deoxyribonucleotide-deoxyribonucleotide base pairs). Such DNA-extended Dicer-substrate siRNAs (DsiRNAs) were demonstrated to be more effective RNA inhibitory agents than corresponding double stranded RNA-extended DsiRNAs. DsiRNA agents were also found to tolerate guide strand mismatches.
US10131910B2	Antisense oligonucleotides for the treatment of Usher syndrome type 2 The invention relates to the fields of medicine and immunology. In particular, it relates to novel antisense oligonucleotides that may be used in the treatment, prevention and/or delay of Usher syndrome type 2A and/or USH2A-associated non syndromic retina degeneration.
US10131907B2	Glycoconjugates of RNA interference agents The present invention relates to agents, compositions and methods for inhibiting the expression of a target gene, comprising an RNAi agent bearing at least one galactosyl moiety. These are useful for delivering the gene expression inhibiting activity to cells, particularly hepatocytes, and more particularly in therapeutic applications.
US10131903B2	Microfluidic platform for synthetic biology applications This invention provides methods and compositions for assembling biological constructs (e.g., plasmids, transformed cells, etc.). In certain embodiments the methods involve encapsulating separate components of the biological construct each in a fluid droplet confined in a fluid channel; optionally mixing droplets from different fluid channels to form a sequenced order of droplets carrying different components of the biological construct in a channel or chamber; and optionally combining two or more droplets each containing different components of the biological construct to permit the components to react with each other in one or more reactions contributing to the assembly of the biological construct.
US10131902B2	Micro RNA isolation from biological fluid The present disclosure provides methods and kits for isolating miRNAs from biological fluids.
US10131900B2	Electroporation-induced electrosensitization Methods of enhancing membrane permeabilization in a cell are provided. A method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the method, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm.
US10131899B2	Bioactive compositions for high avidity cell capture A composition useful for cell capture, the composition comprising a solid substrate on which is affixed a patterned polymer, and a cell-targeting agent attached to said patterned polymer, wherein said cell-targeting agent is exposed. Also described is a method for the preparation of the cell capturing composition, as well as flow through devices in which the cell capturing composition is incorporated. Further described is a method of capturing cells by contacting the cell-capturing composition with a liquid or gaseous sample containing cells. The method for capturing cells may also be a method for testing for the presence of one or more classes or species of cells or cellular organisms in a liquid or gaseous sample.
US10131898B2	Buffers for use with polymerases Amplification reaction mixtures comprising a cationic surfactant and an anionic surfactant are provided.
US10131897B2	Molecules associated with fatty acid biosynthetic pathways and uses thereof The present disclosure relates in part to recombinant microorganisms that include non-native genes encoding PUFA-PKS polypeptides, and to methods of making and using such microorganisms for producing at least one PUFA. In particular, the disclosure further relates to methods and related materials useful for the production of at least one PUFA by heterologous expression of the nucleic acid sequences disclosed herein encoding PUFA-PKS polypeptides.
US10131896B2	Compounds and methods for stabilizing thrombin activity The present invention is directed to compounds useful in stabilizing thrombin activity, thrombin compositions comprising the compounds, methods of using the compounds and methods of identifying compounds capable of stabilizing thrombin activity. The compounds are preferably isolated peptides comprising or interacting with the gamma loop of thrombin.
US10131894B2	Aglycosylated enzyme and uses thereof The present invention relates to compositions comprising an aglycosylated polypeptide having cellobiase activity, and methods for producing and using the same.
US10131893B2	Polypeptides having endoglucanase activity and polynucleotides encoding same The present invention relates to isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains.
US10131892B2	Thermostable cellobiohydrolase A thermostable cellobiohydrolase, having a cellobiohydrolase catalytic domain including: (A) a polypeptide including the amino acid sequence represented by SEQ ID NO: 1 or 2, (B) a polypeptide including an amino acid sequence in which at least one amino acid has been deleted, substituted, or added in the amino acid sequence represented by SEQ ID NO: 1 or 2, and having hydrolysis activity against a substrate of phosphoric acid swollen Avicel at least under conditions of 75° C. and pH 5.5, or (C) a polypeptide including an amino acid sequence having 75% or greater sequence identity with the amino acid sequence represented by SEQ ID NO: 1 or 2, and having hydrolysis activity against a substrate of phosphoric acid swollen Avicel at least under conditions of 75° C. and pH 5.5.
US10131889B1	Candida antarctica lipase B mutant, and methods for making and using the same The present invention relates to the field of bioengineering. It provides a Candida antarctica lipase B mutant and its application. The mutant enzyme overcomes the limit of the parent enzyme that can exhibit high enantioselectivity towards (R)-3-TBDMSO glutaric acid methyl monoester only at temperatures below 5° C. The mutant enzyme successfully increased R-ee value at 5-70° C. The mutant D223V/A281S exhibits high R-ee value (>99%), high conversion rate (80%), and high space-time yield (107.54 g L−1 d−1). The present invention lays a foundation for industrial production of (R)-3-TBDMSO glutaric acid methyl monoester using a biosynthesis approach and provide insights into conformational dynamics-based enzyme design.
US10131888B2	Intracellular protein delivery A secretion signal peptide sequence (SP) in combination with a cleavage inhibition sequence (CIS) fused to a structural gene sequence in a recombinant expression system can be used to express a full length protein with an SP in a cell. Such a fusion protein may be purified to homogeneity from a membrane fraction of the cell. The SP in combination with the CIS is a protein transduction domain that exhibits superior intracellular protein transduction efficiency when the SP precedes the CIS in a N to C-terminus direction.
US10131881B2	Method for preparing induced pluripotency stem cells from mesenchymal stem cells by using phlorotannin fraction The present invention relates to a medium composition for the dedifferentiation of induced pluripotency stem cells, containing a phlorotannin fraction extracted and isolated from one type of brown algae selected from the group consisting of Ecklonia cava, Dictyopteris prolifera, Dictyota coriacea, Sargassum horneri, Ishige okamurai and the like. In addition, the present invention relates to a method for preparing induced pluripotency stem cells by using the medium composition. Induced pluripotency stem cells can be safely, easily and effectively prepared by using mesenchymal stem cells by using the medium composition of the present invention, and the prepared induced pluripotency stem cells can be differentiated into various cells, and thus can be useful as a cell therapeutic agent.
US10131880B2	Pluripotent human adipose adult stem cells: isolation, characterization and clinical implications Methods for the efficient isolation and use of pluripotent adipose-derived stem cells (PASCs) are provided. In certain embodiments the methods involve providing an adipose tissue sample from which the stromal vascular fraction is co-cultured with the adipocyte fraction. PASCs can be isolated with a high degree of purification without requiring an additional cell enrichment process (e.g. cell sorting). PASCs and their conditioned media can be used for tissue regeneration within hours of harvesting the adipose tissue, and without requiring cell expansion. PASCs can grow as floating individual cells, as clusters of cells, or attached to surface(s) of the culture vessel. PASCs do not produce teratomas in vivo, nor do they induce immunorejection upon transplantation, and they achieve a high efficiency in grafting. The cells and compositions can be used for cell therapy and to screen new drugs.
US10131879B2	Methods for reprogramming cells and uses thereof An in vitro human neural multipotent, unipotent, or somatic cell possessing all of the following characteristics: is derived from the reprogramming of a somatic cell, a progenitor cell or a stem cell that exhibits at least a transient increase in intracellular levels of at least one reprogramming agent; is not differentiated from a pluripotent cell; expresses one or more markers of a multipotent, unipotent or somatic cell not characteristic of a neural stem cell, neural precursor cell, neural progenitor cell, neuroblast, or neuron; is not a cancerous cell; is stable and not artificially maintained by forced gene expression and may be maintained in standard neural stem cell media or neural media; and does not exhibit uncontrolled growth, teratoma formation, and tumor formation in vivo; wherein the cell comprises at least one polypeptide or an expression vector encoding at least one polypeptide selected from the group consisting of: Musashi1 (Msi1); Ngn2; Msi1 and Ngn2; Msi1 and methyl-CpG binding domain protein 2 (MBD2); Ngn2 and MBD2; Msi1, Ngn2 and MBD2; Achaete-Scute Homolog 1 (Ascl1); Msi1, Ngn2 and Ascl1; Msi1, Ngn2, MBD2 and Ascl1; Sox2; Msi1, Ngn2 and Sox2; and Msi1, Ngn2, MBD2 and Sox2; wherein the expression vector is transiently expressed.
US10131878B2	Methods for epicardial differentiation of human pluripotent stem cells Methods for generating high-yield, high-purity epicardial cells are described. Wnt/β-catenin signaling is first activated in human cardiac progenitor cells, by, for example, inhibiting Gsk-3 to induce differentiation into epicardial cells. Methods for long-term in vitro maintenance of human cardiac progenitor cell-derived epicardial cells and method comprising chemically defined, xeno-free, and albumin-free culture conditions are also provided.
US10131876B2	Method for automated generation of genetically modified T cells The present invention provides a process for generation of genetically modified T cells, T cell subsets and/or T cell progenitors comprising the steps: a) providing a cell sample comprising T cells, T cell subsets and/or T cell progenitors b) preparation of the cell sample by centrifugation c) magnetic separation of the T cells, T cell subsets and/or T cell progenitors d) activation of the enriched T cells, T cell subsets and/or T cell progenitors using modulatory agents e) genetic modification of the T cells, T cell subsets and/or T cell progenitors f) expansion of the genetically modified T cells, T cell subsets and/or T cell progenitors in a cultivation chamber g) washing of the cultured T cells, T cell subsets and/or T cell progenitors characterized in that all steps are performed in a closed and sterile cell culture system.
US10131874B2	Cell culture support and associated method for cell growth and release A cell culture support comprising a substrate, and a dual stimuli responsive block copolymer immobilized on the substrate, wherein the dual stimuli responsive block copolymer is both thermoresponsive and pH responsive. A method of culturing cells comprising the cell culture support having a dual stimuli responsive copolymer immobilized on a substrate, wherein the dual stimuli responsive copolymer is thermoresponsive and pH responsive; and growing the cells on the cell culture support. By lowering the temperature, cells are released from the cell culture support.
US10131864B2	Polypeptides having protease activity and polynucleotides encoding same The present invention relates to isolated polypeptides having protease activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of using the polypeptides in beer production.
US10131861B2	Corrosion-inhibiting compositions The invention relates to a composition comprising a) at least one N-methyl-N-acylglucamine of formula (I), wherein R1 represents a linear or branched, saturated or unsaturated hydrocarbon chain with 7 to 21 carbon atoms, one or more organic acids of formula (II) and/or the salts thereof, R2—COOM, wherein R2 represents a linear or branched alkyl group or a linear or branched mono- or poly-unsaturated alkenyl group with 5 to 29 carbon atoms, and M represents hydrogen or one or more cations, wherein the cations are present in charge-equalizing amounts, and c) one or more alkanolamines of formula (III), wherein NR1R2R3R1, R2 and R3 represent hydrogen, a linear or branched alkyl group with 1 to 4 carbon atoms, a cycloalkyl group with 5 to 7 carbon atoms, a linear or branched hydroxyalkyl group with 2 to 5 carbon atoms and 1 or 2 hydroxy groups or a hydroxyether group with 2 to 6 carbon atoms, with the provision that at least one of the groups is a hydroxyalkyl group or a hydroxyether group.
US10131860B2	Dialkyl polysulfide, process for preparing dialkyl polysulfide, extreme pressure additive, and lubricating fluid composition The present invention provides a dialkyl polysulfide which can be suitably used as an extreme pressure additive that can be added to a lubricant in a wide range of amounts, that enables effective formation of a film of a metal sulfide on a metal surface, and that is less likely to cause corrosion of the metal surface. In particular, provided is a dialkyl polysulfide containing compounds represented by General Formula (1) (where R1 and R2 each represent an alkyl group, and n is an integer from 1 to 6), wherein the total content of a compound in which n in General Formula (1) is 2 and a compound in which n in General Formula (1) is 3 is in the range of 80 to 100 mass % relative to the entire amount of the compounds represented by General Formula (1).
US10131857B2	Gasification quench system A system includes a quench system that may cool a syngas generated in a gasification chamber. The quench system includes a quench chamber, a dip tube that may direct the syngas from the gasification chamber into a quench liquid to cool the syngas to generate a cooled syngas, a draft tube disposed circumferentially about the dip tube and that may receive the cooled syngas in a first direction. A first passage is disposed between a first wall of the dip tube and a second wall of the draft tube. The system also includes a first baffle that may receive the cooled syngas from the first passage. The first baffle may split a flow of the cooled syngas into a first syngas flow and a second syngas flow, and the first baffle may redirect the first syngas flow in a second direction different from the first direction.
US10131855B2	Method and device for pyrolysis of biomass to produce syngas A method for pressurized pyrolysis of biomass in a pressurized pyrolysis furnace, including: 1) crushing and screening biomass; collecting biomass having desired particle sizes; and delivering the biomass having desired particle sizes to a pulse-type feeding system; 2) transporting the biomass to a pyrolysis furnace via the pulse-type feeding system; synchronously initiating microwave and a plasma torch, the microwave producing a microwave field in the pyrolysis furnace, working gas of the plasma torch being ionized for the first time to produce plasma jet entering the pyrolysis furnace; and 3) allowing the syngas generated in 2) to continue moving upwards and introducing the syngas out from the top of the pyrolysis furnace; chilling the syngas; introducing the syngas to a cyclone separator to separate residues; and then cooling and purifying the syngas using a cooling device and a purifying device, respectively, to produce clean syngas.
US10131852B1	Method for forming reduced thiophene diesel fuel using a graphene oxide adsorbent The present disclosure provides a method for removing sulfur compounds from a fuel containing sulfur compounds. The method includes contacting the fuel with an adsorbent that comprises a carbonaceous material doped with nanoparticles of aluminum oxide to reduce the concentrations of the sulfur compounds. The carbonaceous material is at least one selected from the group consisting of activated carbon, carbon nanotubes, and graphene oxide, and the adsorbent has a weight ratio of C to Al in the range from 3:1 to 30:1, and a weight ratio of C to O in the range from 1:1 to 10:1.
US10131850B2	Naphtha and methanol mixed catalytic cracking reaction process A naphtha and methanol mixed catalytic cracking reaction process involves a simultaneous cracking reaction of naphtha and methanol using a circulating fluidized-bed reactor comprising a reactor, a stripper, and a regenerator. The naphtha is supplied from the bottom part of the reactor at a position between 0%˜5% of the total length of the reactor, and the methanol is supplied from the bottom part of the reactor at a position between 10%˜80% of the total length of the reactor. The catalytic cracking reaction process uses the circulating fluidized-bed reactor and can crack naphtha and methanol simultaneously by having different introduction positions for the naphtha and methanol in the reactor, which is advantageous for heat neutralization, so that energy consumption can be minimized and also the yield of light olefins can be improved by suppressing the production of light saturated hydrocarbons such as methane, ethane and propane.
US10131843B2	Vertical alignment layer comprising cyclic olefin copolymer The present invention relates to a vertical alignment layer including a cyclic olefin copolymer, and more specifically, the present invention relates to a vertical alignment layer capable of having alignment even in a low temperature process, and exhibiting excellent liquid crystal vertical alignment by including a cyclic olefin copolymer having a specific substituent.
US10131838B2	Compositions for cooling materials exposed to the sun The present invention provides for a composition comprising a pigment, wherein the composition is suitable for coating a surface that is, or is expected to be, exposed to the sun. The pigment comprises particles that fluoresce in sunlight, thereby remaining cooler in the sun than coatings pigmented with non-fluorescent particles. The particles comprise solids that fluoresce or glow in the visible or near infrared (NIR) spectra, or that fluoresce when doped. Suitable dopants include, but are not limited to, ions of rare earths and transition metals.
US10131837B2	Fluorescent material, light-emitting device, and method for producing fluorescent material A method for producing a fluorescent material can be provided. The method includes preparing fluorescent material particles that contain a fluoride having a composition including Mn, at least one selected from the group consisting of alkali metal elements and NH4+, and at least one selected from the group consisting of Group 4 elements and Group 14 elements; causing at least one cation selected from rare-earth elements and a phosphate ion to come into contact with each other in a liquid medium containing the fluorescent material particles to obtain rare-earth phosphate-adhered fluorescent material particles including the fluorescent material particles to which the rare-earth phosphate is adhered; and separating the rare-earth phosphate-adhered fluorescent material particles from the liquid medium.
US10131835B2	Moisture-resistant phosphor compositions and associate methods A phosphor composition is derived from combining K2SiF6:Mn4+ in solid form with a saturated solution of a manganese-free complex fluoride including a composition of formula I: A3[MF6], where A is selected from Na, K, Rb, and combinations thereof and M is selected from Al, Ga, In, Sc, Y, Gd, and combinations thereof. The composition of formula I: A3[MF6] has a water solubility lower than a water solubility of K2SiF6. A lighting apparatus including the phosphor composition is also provided.
US10131834B2	Self-suspending modified proppant system for carbon dioxide based fracturing fluids Self-suspending proppants including proppant particles coated with a CO2-philic coating are provided. The CO2-philic coating may be lightly crosslinked and may have a physical structure that constrains CO2 molecules. Methods of making self-suspending proppants may include coating a proppant particle with a polymerizable precursor material of a CO2-philic material and polymerizing the polymerizable precursor material to form a self-suspending proppant are also provided. Additionally, hydraulic fracturing fluids that may include a CO2-based fluid and the self-suspending proppants and methods of treating subterranean formations by contacting a subterranean formation with hydraulic fracturing fluid and propagating at least one subterranean fracture are provided.
US10131833B2	Self-suspending modified proppant system for carbon dioxide based fracturing fluids Self-suspending proppants including proppant particles coated with a CO2-philic coating are provided. The CO2-philic coating may be lightly crosslinked and may have a physical structure that constrains CO2 molecules. Methods of making self-suspending proppants may include coating a proppant particle with a polymerizable precursor material of a CO2-philic material and polymerizing the polymerizable precursor material to form a self-suspending proppant are also provided. Additionally, hydraulic fracturing fluids that may include a CO2-based fluid and the self-suspending proppants and methods of treating subterranean formations by contacting a subterranean formation with hydraulic fracturing fluid and propagating at least one subterranean fracture are provided.
US10131829B2	Composition containing 2,3,3,3-tetrafluoropropene and 1,2-difluoroethylene Compositions containing 2,3,3,3-tetrafluoropropene and 1,2-difluoroethylene, that can be used in multiple fields of application. The composition can include from 45 to 90 mol % of 2,3,3,3-tetrafluoropropene and from 55 to 10 mol % of, 1,2-difluoroethylene. The composition can include from 55 to 80 mol % of 2,3,3,3-tetrafluoropropene and from 45 to 20 mol % of 1,2-difluoroethylene. The composition can include from 62 to 69 mol % of 2,3,3,3-tetrafluoropropene and from 38 to 31 mol % of 1,2-difluoroethylene at a temperature of between −30° C. and 56° C. and a pressure of between 1 and 15 bar.
US10131827B2	Working fluid for heat cycle, composition for heat cycle system, and heat cycle system To provide a working fluid which has cycle performance sufficient as an alternative to R410A while the influence over global warming is sufficiently suppressed, which does not significantly increase the load to an apparatus as compared with a case where R410A is used, and which can be stably used continuously without any special measures, a composition for a heat cycle system contains the working fluid, and a heat cycle system employs the composition. A working fluid for heat cycle, wherein the global warming potential is less than 300; the product of the relative coefficient of performance and the relative refrigerating capacity is at least 0.820 relative to R410A in a standard refrigerating cycle under conditions of an evaporation temperature of 0° C., a condensing temperature of 40° C., a supercoiling degree of 5° C. and a degree of superheat of 5° C.; the relative compressor discharge gas pressure is at most 1.100; the lower limit of the combustion range by method A in High Pressure Gas Safety Act is at least 5 vol %; and the pressure will not exceed 2.00 MPaG in a combustion test by method A in High Pressure Gas Safety act under 0.98 MPaG at 250° C.
US10131822B2	Peelable adhesive composition The invention relates to an adhesive composition comprising at least one natural latex and at least one polymeric composition having a glass transition temperature ranging from −50° C. to 0° C. The invention also relates to a membrane obtained after drying the adhesive composition according to the invention, to a combination of a flexible surface coating with an adhesive composition according to the invention, to a method for applying a flexible surface coating onto a substrate as well as a substrate coated with a peelable adhesive membrane according to the invention.
US10131821B2	Adhesive label liner sheet modifications for retaining unneeded label sections on liner One or more cuts is provided in a label liner sheet near the area of a cutout within the label, such as the center hole in a CD label, in order to facilitate reliable separation of the cutout from the label and retention of the cutout on the liner sheet as the label is peeled from the liner. The majority of the cut runs generally parallel to the cutout boundary underneath the cutout, and the ends of the cut cross the boundary at two separate boundary crossing points on either side of the portion of the cut running parallel to the boundary. The cut first causes a flap to be created in the liner sheet and partially lifted as the label is beginning to be peeled away. Thereafter, as the peel line passes the flap area, the cutout experiences the full retentive strength of the label's pressure sensitive adhesive primarily at the two boundary crossings, and the cutout is pulled from the label and retained on the liner sheet as the adhesive force overcomes the cohesive force.
US10131813B2	Ambient cure compositions for making coatings having humidity and corrosion resistance and methods of use The present invention provides substantially isocyanate-free multicomponent compositions useful in making rapid dry primer compositions and coatings, the compositions comprising one or more carboxylic acid compounds that contain one of a benzothiazole, benzoxazole, or benzimidazole group, preferably, that contain a benzothiazole group, one or more hydrophobic sulfonic acid catalyst, one or more pigment, extender or filler, one or more a) polycarbamates from alkyd polyol or acrylic polyol and one or more b) a polyaldehydes or the acetal or hemiacetal thereof as a second component. The multicomponent compositions cure quickly at a temperature of from 0° C. to less than 80° C. to form a crosslinked polyurethane coating having improved humidity and corrosion resistance.
US10131809B2	Optical layered body, polarizer and image display device The present invention provides an optical layered body having excellent antistatic properties, optical characteristics, hardness, adhesion, and interference fringe prevention performance, which can be produced at a low cost.An optical layered body having a hard coat layer provided on a triacetylcellulose substrate, wherein a resin composition used for forming the hard coat layer contains a quaternary ammonium salt-containing polymer, a binder resin, and a solvent; the quaternary ammonium salt-containing polymer has a higher hydrophilicity than the binder resin; and the binder resin contains two or more resin components having different hydrophilicities.
US10131808B2	Solventborne pigment pastes comprising metallic pigments and use thereof for producing solventborne effect coating materials Described are solventborne pigment pastes comprising lamellar effect pigments. Also described is the use of the solventborne pigment pastes comprising lamellar effect pigments for producing solventborne effect coating materials. Further described is a process for producing solventborne effect coating materials.
US10131805B2	Ink, ink stored container, inkjet recording apparatus, and printed matter Provided is an ink containing a wax, a plurality of organic solvents, and water, wherein the plurality of organic solvents include a compound having a solubility parameter of 9 or greater but 11 or less and a compound having a saturated vapor pressure at 100° C. of 20 mmHg or greater but 400 mmHg or less.
US10131803B2	Preparation method of graphene and dispersed composition of graphene Disclosed herein are a preparation method of graphene, capable of easily preparing a graphene flake having a smaller thickness and a large area, and a dispersed composition of graphene obtained using the same. The preparation method of graphene includes applying a physical force to dispersion of a carbon-based material including graphite or a derivative thereof, and a dispersant, wherein the dispersant includes a mixture of plural kinds of polyaromatic hydrocarbon oxides, containing the polyaromatic hydrocarbon oxides having a molecular weight of 300 to 1000 in a content of 60% by weight or more, and the graphite or the derivative thereof is formed into a graphene flake having a thickness in nanoscale under application of a physical force.
US10131802B2	Nanosilica based compositions, structures and apparatus incorporating same and related methods Silica based compositions that may be used coatings, films or other cast structures, as well as related methods and resulting structures are provided. In one embodiment, a hybrid nanosilica (HNS) composition includes tetraethylorthosilicate (TEOS), methyl triethoxysilane (MTEOS) and glycidoxypropyltrimethoxysilane (GPTMS). The composition may be used as a coating to provide various types of protection and device performance enhancement. For example, the composition may be used for impact protection or corrosion resistance. In one particular embodiment, optically enhancing nanoparticles may be dispersed throughout the HNS material and used as an antireflective coating (ARC) for various optical purposes.
US10131799B2	Antifouling coating composition and its use on man-made structures The invention pertains to an antifouling coating composition comprising a copper acrylate polymer, 2-(p-chlorophenyl)-3-cyano-4-bromo-5-trifluoromethyl pyrrole (tralopyril), and solvent, with the coating composition being substantially free of further biocidal compounds, wherein the copper acrylate polymer is present in an amount of 60-99 wt. % and the tralopyril is present in an amount of 0.1-30 wt. %, the weight percentages for copper acrylate polymer and tralopyril being calculated on the dry weight of the coating composition. In one embodiment, the coating composition comprises 30-70 wt % of solvent, the weight percentage of solvent being calculated on the wet weight of the coating composition. It has been found that the coating composition according to the invention combines a good antifouling performance against both weed and shell fouling, for at least 12 months, i.e. a yacht season, with a high gloss finish, and, when a suitable application method is used, a smooth and level surface.
US10131798B2	Controlled release composition containing DCOIT A composition containing 4,5-dichloro-2-n-octylisothiazolin-3-one, an activated carbon having a surface area of at least 700 m2/g and a cured isocyanate.
US10131796B2	Powder coating composition A coating composition comprising a blend of one or more polyester resins having a lower average molecular weight and higher melt flow index, where the coating composition is in the form of a powder having particles with a fine particle size distribution, and where the coating composition is configured to form a thin coating (34) that is substantially free of pores.
US10131790B2	Infrared-reflective pigment and infrared-reflective coating composition To provide an infrared-reflective pigment and infrared-reflective coating composition provided with both high infrared-light reflecting properties and high visible-light transparency. Provided is a flake-shaped infrared-reflective pigment, the infrared-reflective pigment 1 characterized by being provided with a layered body 13 having at least one metal thin-film layer 11 and at least two transparent dielectric layers 12, the film thickness of the dielectric layer 12 being (an integer multiple of λ/4n)±10 nm, where λ is the wavelength of incident light in a visible-light peripheral region and n is the refractive index of the dielectric layer 12. Also provided is an infrared-reflective coating composition containing the infrared-reflective pigment 1.
US10131787B2	Polycarbonate resin composition and molded article comprising the same A polycarbonate resin composition and a molded article using the same is disclosed. The polycarbonate resin composition includes a polycarbonate resin (A); a rubber-modified aromatic vinyl copolymer (B); and an additive for laser directed structuring (C). The polycarbonate resin composition has a heat deflection temperature (HDT) of about 100° C. or more.
US10131785B2	Polyester resin composition with excellent impact resistance and light reliability and molded article using the same A polyester resin composition and a molded article produced using the same. The polyester resin composition includes: (A) two polyester resins including an aliphatic ring structure and having different trans/cis isomer ratios in the aliphatic ring; (B) a white pigment; and (C) an inorganic filler, wherein the polyester resin composition has a crystallization temperature (Tc) of about 230° C. to about 250° C., as measured by differential scanning calorimetry (DSC) while cooling the resin composition at a cooling rate of −100° C./min. Exemplary compositions include a first poly(1,4-cyclohexylene dimethylene terephthalate) and a second poly(1,4-cyclohexylene dimethylene terephthalate) having different trans/cis isomer ratios in the cyclohexylene rings thereof, titanium oxide, glass fiber, and wollastonite.
US10131782B2	Polyoxymethylene compositions, method of manufacture, and articles made therefrom Reinforced polyoxymethylene compositions including 50 to 90 wt. % of a polyoxymethylene; 10 to 50 wt. % of glass fibers, wherein the weight of the polyoxymethylene and the glass fibers total 100 wt. %; 1 to less than 4.0 wt. % of a (meth)acrylic polymer additive, based on the total weight of the polyoxymethylene and the glass fibers; 0.1 to 5 wt. %, preferably 0.1 to 2.5 wt. % of a heat stabilizer; and 0.1 to 5 wt. % of an antioxidant, wherein the amounts of the (meth)acrylic polymer additive, the heat stabilizer, and the antioxidant are based on the total weight of the polyoxymethylene and the glass fibers.
US10131779B2	Blends of styrene-butadiene copolymers Polymer blend comprising 95 to 100% of a component A) and 0 to 5% of additives, where A) is consisting of polymers A1) to A4): A1) 50 to 75% of a star shaped block copolymer A1 which comprises at least 2 terminal vinylaromatic hard blocks S and diene soft blocks B, where the proportion of the hard blocks S is from 65 to 90%, and Mn of block S is 35000 to 200000; A2) 5 to 15% of block copolymer A2 which comprises 2 terminal vinylaromatic hard blocks S1 and S2 and random copolymer blocks (B/S) consisting of 20 to 60% vinylaromatic monomers, and 80 to 40% dienes where the proportion of blocks S1 and S2 is 40 to 60%; and Mn of blocks S1 is 35000 to 200000, and Mn of blocks S2 is 5000 to 30000 and the molar S1/S2 ratio is 1:0.5 to 1:10; A3) 3 to 10% of an block copolymer A3 built up from vinylaromatic hard blocks S and from random soft blocks B/S consisting of 60 to 30% vinylaromatic monomers and 40 to 70% dienes, where the diene content is less than 50% and the proportion of the soft phase is at least 60%; and A4) 10 to 35% polystyrene A4; whereby the ratio of A1) to A2) to A3) is from 7 : [1.2 to 1.9] : [0.5 to 12], have particular mechanical properties.
US10131774B2	Fiber optic cable having low thermal strain and methods of manufacturing the same according to ASTM D4065 and D638 A polymer composition is provided. The polymer composition includes a polyolefin, at least 30% by weight of a thermoplastic elastomer, and a filler material. When the polymer composition is formed into an article having a longitudinal axis, the polymer composition has an average coefficient of thermal expansion along a longitudinal axis of less than or equal to 150×10−6 m/mK as measured from −40° C. to 25° C. Further, the polymer composition has an elastic modulus of less than 3000 MPa as measured using dynamic mechanical analysis (ASTM D4065), and the polymer composition has an elongation at break of greater than 200% along the longitudinal axis (measured according to ASTM D638). An article made from the polymer composition and a cable including the polymer composition are also provided.
US10131768B2	Liquid (meth)acrylic syrup for impregnating a fibrous substrate, method of impregnating a fibrous substrate, composite material obtained following polymerisation of the pre-impregnated substrate The present invention relates to a liquid (meth)acrylic syrup for impregnating a fibrous substrate. The present invention relates in particular to a viscous liquid syrup mainly containing methacrylic or acrylic components. The invention also relates to a process for manufacturing such a syrup. The invention also relates to a process for impregnating a fibrous substrate or long fibers with said viscous liquid syrup. The invention also relates to a fibrous substrate preimpregnated with said syrup, which is useful for manufacturing mechanical or structured parts or products.The present invention also relates to a manufacturing process for manufacturing mechanical or structured parts or articles and to three-dimensional mechanical or structured parts obtained by this process.The invention applies to the preparation of mechanical parts or structural elements made of fire-resistant thermoplastic composite material.
US10131765B2	Method for manufacturing composite material polarizable under the action of a weak electric field The present invention relates to a composite (13), characterized in that it comprises: at least one ferroelectric organic polymer with relaxation properties, and at least one phthalate-based plasticizer.
US10131763B2	Modified natural rubber, process for producing same, rubber composition for tire, and pneumatic tire The present invention provides a modified natural rubber having a good balance of improved fuel economy, heat-aging resistance, processability, and breaking resistance, and a method for producing such a rubber. The present invention also provides a tire rubber composition and a pneumatic tire which are prepared using the modified natural rubber. The present invention relates to a highly purified, modified natural rubber whose pH is adjusted to 2 to 7.
US10131757B2	Methods for surface modification of materials The invention concerns methods and compositions for modifying a surface of a material by anchoring a surface modifying additive to a polymer matrix using an anchor molecule, wherein the surface modifying additive and the anchor molecule are both added to a melt phase of the polymer matrix.
US10131755B2	System and method for formation of thin films with self-assembled monolayers embedded on their surfaces The present invention relates to a method for the formation of virtually defect-free monolayers of particles with long-range order. The technique involves assembling the monolayer of particles on the interface between a solidifiable liquid and a fluid, which can be air or another liquid, ordering the particles using an electric field and then solidifying the former, e.g., by applying UV light. The monolayer becomes embedded on the surface of the solidified film. The monolayers can be coated onto the surface of materials to optimize their mechanical, thermal, electrical and optical properties.
US10131754B2	Preparation of large ultra-thin free-standing polymer films A method of making large ultrathin free-standing polymer films without use of a sacrificial layer includes the steps of providing a substrate, applying a polyelectrolyte material to said substrate, applying a polymer material onto said substrate and onto said polyelectrolyte material, and directly delaminating said polymer material from said substrate and said polyelectrolyte to produce the ultrathin free-standing polymer film.
US10131749B2	Sulfur compound and composition for optical materials containing same According to one preferred embodiment of the present invention, a composition for optical materials, which contains a compound represented by formula (1) and a compound represented by formula (2), is able to be provided. This composition for optical materials enables stable storage of a compound represented by formula (2) at low cost, and also enables stable storage thereof with respect to temperature change. In addition, this composition for optical materials enables the achievement of an optical material which has good light resistance. (In formula (1), in represents an integer of 0-4; and n represents an integer of 0-2.) (In formula (2), m represents an integer of 0-4; and n represents an integer of 0-2.)
US10131745B2	Polymeric nanogels with degradable backbones and from gras components, and compositions and methods thereof The invention generally relates to novel polymers and polymeric nanogels having biodegradable polymeric backbones, and compositions and methods of preparation and use thereof, for example, as guest-host polymer nano-assemblies and nano-delivery vehicles, which offer utilities in diverse fields including drug delivery, diagnostics and specialty materials.
US10131743B2	Method for working up alkaline polyether polyols This invention relates to a process for preparing polyols which contain oxyalkylene units. This process comprises neutralizing a crude polyol by addition of an acid, optionally removing water, and removing the salts formed by neutralization. The crude polyol is contacted with the acid for at least 5 minutes.
US10131735B2	Low-temperature radical polymerisation of alkoxyamines The present invention relates to a process for the radical polymerization of alkoxyamines at low temperature, typically at temperatures as low as −50° C., in the presence of a photoinitiator.
US10131733B2	Catalyst composition, method for hydrogenating styrenic block copolymers, and hydrogenated polymer A catalyst composition, a method for hydrogenating styrenic block copolymer employing the same, and a hydrogenated polymer from the method are provided. The method for hydrogenating styrenic block copolymer includes subjecting a hydrogenation process to a styrenic block copolymer in the presence of a catalyst composition. In particular, the catalyst composition includes an oxide carrier, and a catalyst disposed on the oxide carrier, wherein the catalyst includes a platinum-and-rhenium containing phosphorus compound.
US10131732B2	Method to produce functionalized, low viscosity ethylene-based polymers The invention provides a process to form a “functionalized ethylene-based polymer” from an ethylene-based polymer and at least one polar compound, said process comprising thermally treating a composition comprising the ethylene-based polymer, the at least one polar compound, and at least one peroxide, in at least one extruder comprising at least one barrel, to form a polymer melt; and wherein the at least one peroxide has a half life, at the maximum barrel temperature of the at least one extruder, of less than of the minimum residence time of the polymer melt in the at least one extruder. The invention further provides a composition comprising at least the following: a) an ethylene-based polymer comprising a melt viscosity, at 350° F. (177° C.), less than 50.000 cP, and b) at least one peroxide comprising a half-life from 0.10 to 2.00 minutes, at a temperature from 160° C. to 190° C.
US10131730B2	Resist composition and patterning process A resist composition comprising a polymer comprising recurring units of lactone and a PAG is provided. The resist composition has a high dissolution contrast during organic solvent development, and improved resist properties including MEF and CDU and forms a fine hole pattern with improved roundness and size control.
US10131727B2	Solid state matrix, process of preparation thereof, and process of preparation of theaflavins The present invention relates to a process for the development of a highly efficient solid state matrix by the activation of acrylate based polymer resin having specialized functional groups with 1,1-Carboxyl diimidazole for immobilizing biologically active macromeloecules such as oxidases, in particular plant oxidases and the most preferred being tea polyphenol oxidase through indirect covalent bonding/cross linking on such activated polymer resin support, are thermally stable, gives very high number of turnovers in vitro (“n” times) with tea substrate forming exclusive product Theaflavins without any loss of biological activity and leaving the product remaining in vitro with adherence to matrix rendering the matrix safe towards product poisoning and subsequent partial or complete loss of biological activity of the matrix bound enzyme system and thus well adapted to and well suited biorectors based on such systems. It is unique with respect to its recyclability or otherwise uneconimical tea substrates such as seed and flower substrates into theaflavins both with respect to crude substrate or purified ones.
US10131725B2	Production of high haze films using metallocene-based catalyst systems in cyclohexene Methods for preparing metallocene-based catalyst systems containing an activator-support are disclosed. These methods are directed to contacting an activator-support, an organoaluminum compound, and a mixture containing a metallocene compound and cyclohexene or a mixture of cyclohexane and 1-hexene, resulting in catalyst systems with increased catalytic activity for the polymerization of olefins. The olefin polymers can be used to produce film products with high haze values.
US10131724B2	Process for the production of high internal phase emulsion foams A method for polymerizing a High Internal Phase Emulsion foam including exposing a High Internal Phase Emulsion foam comprising a photoinitiator to an Ultraviolet light source, and partially polymerizing the top surface of the emulsion.
US10131722B2	Method for preparing terminal-modified conjugated diene polymer, terminal-modified conjugated diene polymer, rubber composition and tire This disclosure is to provide a method for preparing a terminal-modified conjugated diene polymer which achieves an extremely high compounding amount of cis-1,4 without complicated preparing conditions, a terminal-modified conjugated diene polymer obtained via the method, a rubber composition containing the terminal-modified conjugated diene polymer, and a tire using the rubber composition. This disclosure is A method for preparing a terminal-modified conjugated diene polymer comprising: polymerizing a conjugated diene compound by using a polymerization catalyst composition and modifying a polymer obtained via the polymerization by using a modifier, wherein the polymerization catalyst composition contains a rare earth element compound, and a coordination compound having a cyclopentadiene skeleton selected from substituted or unsubstituted cyclopentadienes, substituted or unsubstituted indenes, and substituted or unsubstituted fluorenes, and wherein the polymerization and modification is performed in a one-pot way.
US10131721B2	Polymeric acid catalysts and uses thereof Polymers including acidic monomers and ionic monomers connected to form a polymeric backbone are disclosed. The polymers may also include, e.g., acidic-ionic monomers within the polymeric backbone. Each acidic monomer may independently include at least one Bronsted-Lowry acid, and each ionic monomer may independently include at least one nitrogen-containing cationic group or phosphorous-containing cationic group. The acidic monomers and ionic monomers may make up, e.g., at least about 30% of the monomers of the polymer, based on the ratio of the number of acidic monomers and ionic monomers to the total number of monomers present in the polymer. The total number of ionic monomers may, e.g., exceed the total number of acidic monomers in the polymer. The polymer may be substantially insoluble in water.
US10131718B2	Cross-linked hyaluronic acid grafted with dextran A hyaluronic acid product is comprising a cross-linked hyaluronic acid and one or more dextran molecules. The hyaluronic acid is cross-linked by ether bonds, and the one or more dextran molecules are covalently grafted to the cross-linked hyaluronic acid.
US10131717B2	Topically administered, skin-penetrating glycosaminoglycan formulations suitable for use in cosmetic and pharmaceutical applications The present invention relates to topical glycosaminoglycan compositions, particularly hyaluronan compositions, that facilitate the penetration of modified glycosaminoglycans through the skin barrier into the epidermal and dermal layers of the skin, thereby allowing for the dermal administration of a glycosaminoglycan, such as hyaluronan, without requiring an injection. Through their ability to deliver hyaluronan to the epidermal and dermal layers, the present formulations are therefore suitable for use in dermal rejuvenation, enhancement, hyaluronan replenishment and protection therapy. The glycosaminoglycan compositions are also useful as delivery devices to facilitate the dermal and transdermal delivery of cosmetically and pharmaceutically active substances, including pharmaceuticals, polypeptides, proteins and similarly sized biomacromolecules, through the skin barrier.
US10131715B2	Cellulose particulate material The invention relates to plant-derived cellulose-containing particles useful as rheology modifiers and to a process for preparing cellulose-containing particles from plant material, which process involves treating said plant material with a peroxide reagent. The process can be controlled to produce cellulose-containing particle having a viscosity up to about 7500 or 8000 cps.
US10131712B2	Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors The present invention concerns compositions and methods of use of bispecific antibodies comprising at least one binding site for a tumor-associated antigen (TAA) and at least one binding site for an antigen expressed on an effector T cell, NK cell, monocyte or neutrophil. The bispecific antibodies are of use for inducing an immune response against a TAA-expressing tumor. The methods may comprising administering the bispecific antibody in combination with one or more therapeutic agents such as antibody-drug conjugates, interferons (preferably interferon-α), and/or checkpoint inhibitor antibodies. The bispecific antibody is capable of targeting effector T cells, NK cells, monocytes or neutrophils to induce leukocyte-mediated cytotoxicity of cancer cells. The cytotoxic immune response is enhanced by co-administration of interferon, checkpoint inhibitor antibody and/or ADC. In preferred embodiments, the checkpoint inhibitor is a chimeric or humanized anti-PD1 antibody as described herein.
US10131709B2	Nucleic acid molecules encoding monoclonal antibodies specific for IL-22 Provided are novel binding molecules of human origin, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize antigens such as native endogenous proteins associated with, e.g., immune response, autoimmune disorders, inflammatory diseases, metabolic disorders, vascular function, neurodegenerative diseases or tumors. More particularly, a human Auto-Immunosome and corresponding monoclonal antibody reservoir are provided. In addition, pharmaceutical compositions, kits and methods for use in diagnosis and therapy of are described.
US10131707B2	Treatment of sepsis and septic shock The technology described herein is directed to the treatment of sepsis and/or septic shock by, e.g. administering an agent that can reduce the level of circulating citrullated histones.
US10131706B2	Anti-factor Bb antibodies A pharmaceutical composition includes an isolated anti-Bb antibody or antigen binding portion thereof produced by a hybridoma cell line deposited under ATCC Accession Number PTA-8543 or an isolated anti-Bb antibody or antigen binding portion thereof that competitively inhibits binding of the antibody or antigen binding portion produced by the hybridoma cell line deposited under ATCC Accession Number PTA-8543 to the Bb segment of factor B; and a pharmaceutically acceptable carrier.
US10131705B2	Vaccines and diagnostics for the ehrlichioses The present invention concerns VLPT immunoreactive compositions for E. chaffeensis and compositions related thereto, including vaccines, antibodies, polypeptides, peptides, and polynucleotides. In particular, epitopes for E. chaffeensis VLPT are disclosed.
US10131701B2	Human leucine zipper/trail recombinant polypeptides Disclosed are recombinant polypeptides that include human TRAIL sequences as well as human leucine zipper motifs as well as polynucleotides that encode the recombinant polypeptides, expression vectors that comprise the polynucleotides, pharmaceutical compositions comprising the polypeptides, and methods of using the pharmaceutical compositions for the treatment of cancer. Further disclosed are TRAIL sequences with stabilizing mutations and methods of expressing the disclosed polypeptides in E. coli.
US10131699B2	EphA2 T-cell epitope agonists and uses therefore EphA2 T-cell epitope are provided herein. The epitopes include peptides corresponding to specific fragments of human EphA2 protein containing one or more T-cell epitopes, and conservative derivatives thereof. The EphA2 T-cell epitopes are useful in an assay, such as an ELISPOT assay, that may be used to determine and/or quantify a patient's immune responsiveness to EphA2. The epitopes also are useful in methods of modulating a patient's immune reactivity to EphA2, which has substantial utility as a treatment for cancers that overexpress EphA2, such as renal cell carcinoma (RCC). The EphA2 epitopes also can be used to vaccinate a patient against EphA2, by in vivo or ex vivo methods.
US10131698B2	Synthetic antimicrobial peptides Anti-microbial compositions comprising synthetic peptides for therapeutic use are described. These compositions have found applications in treating human and plant infections.
US10131692B2	Vasopressin-2 receptor agonists Vasopressin-2 receptor agonists, pharmaceutical compositions thereof and methods for using the foregoing for treating diabetes insipidus, primary nocturnal enuresis, and nocturia.
US10131690B2	C6S specific transporter molecules The present invention relates to isolated molecules, peptides, and polypeptides of specific consensus sequences or structures, and to compounds comprising or consisting of such molecules, peptides or polypeptides, that function as transporter moieties or compositions specifically recognizing the proteoglycan, chondroitin 6-sulfate (C6S). The isolated molecules, peptides, polypeptides and compounds of the invention may be conjugated or otherwise linked to a biologically active moiety (BAM). Thus the BAM conjugates allow the specific targeting and delivery of the BAM, which may be, for example, a peptide, chemical entity or nucleic acid, into the cytoplasm and/or nuclei of C6S expressing cells in vitro and in vivo.
US10131689B2	Separation and purification method for vancomycin hydrochloride of high purity Provided is a separation and purification method for vancomycin hydrochloride of high purity. The method comprises the following steps: (1) obtaining a vancomycin hydrochloride solution from a crude vancomycin product by ion exchange chromatography and obtaining a concentrate by nanofiltration desalination and concentration; (2) adjusting the concentrate with a hydrochloric acid solution and then performing a column chromatography using a reverse chromatography column for the adjusted concentrate; (3) collecting the chromatographic solution of vancomycin to obtain a mixed chromatographic solution; (4) adjusting the mixed chromatographic solution, and separating the solution and the salts by nanofiltration desalination and concentration to obtain a concentrate; and (5) obtaining a vancomycin dry powder with a chromatographic purity of up to 99% and a pure white appearance by dehydrating and drying the concentrate of step (4), or by solvent crystallization or salting-out crystallization.
US10131681B2	Aminophosphinic derivatives that can be used in the treatment of pain The present invention relates to a compound of the following general formula (I): R1—NH—CH(R2)—P(═O)(OR3)—CH2—C(R4)(R5)—CONH—CH(R6)—COOR7 (I) or a pharmaceutically acceptable salt of the latter, an isomer or a mixture of isomers in any proportions, especially a mixture of enantiomers, and in particular a racemic mixture, for which R1 represents a —C(═O)—O—C(R8)(R9)—OC(═O)—R10 group; R2 represents an optionally substituted hydrocarbon-based chain, an aryl or heteroaryl group or a methylene group substituted by a heterocycle; R3 represents a hydrogen atom or a —C(R12)(R13)—OC(═O)—R14 group; R4 and R5 form, together with the carbon that bears them, a saturated hydrocarbon-based ring or an optionally substituted piperidine ring or R4 represents a hydrogen atom and R5 represents a phenyl or a benzyl that is optionally substituted, a heteroaromatic ring or a methylene group substituted by a heterocycle; R6 represents an optionally substituted hydrocarbon-based chain or a phenyl or a benzyl that is optionally substituted; and R7 represents a hydrogen atom or a benzyl, alkyl, heteroaryl, alkylheteroaryl, —CHMe-COOR18, —CHR19—OC(═O)R20 and —CHR19—OC(═O)OR20 group. The present invention also relates to the use of these compounds as a medicinal product, and in particular for the treatment of pain, more advantageously neuropathic and neuroinflammatory pain, to their method of synthesis and also to the compositions containing them.
US10131680B1	Group 4 metal element-containing alkoxy compound, preparing method thereof, precursor composition including the same for film deposition, and method of depositing film using the same The present disclosure provides a Group 4 metal element-containing novel alkoxy compound, a method of preparing the Group 4 metal element-containing alkoxy compound, a precursor composition including the Group 4 metal element-containing alkoxy compound for depositing a film, and a method of depositing a Group 4 metal element-containing film using the precursor composition.
US10131666B2	Heterocyclic morphinan derivatives and use thereof The application is directed to compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, and Z are defined as set forth in the specification. In certain embodiments, the invention is also directed to compounds of Formula II-VII and the pharmaceutically acceptable salts and solvates thereof. The invention is also directed to use of compounds of Formula I to VII, and the pharmaceutically acceptable salts and solvates thereof, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the invention are especially useful for treating pain.
US10131665B2	Processes for producing diazabicyclooctane compounds A crystalline form of a diazabicyclooctane derivative represented by the following Formula (VII), and processes for producing the same:
US10131661B2	High-solubility acetone-added pyrroloquinoline quinone salt There are provided an alkali metal salt of 5-hydroxy-4-oxo-5-(2-oxopropyl)-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid, a method for producing the alkali metal salt, and a cocrystal comprising the alkali metal salt.
US10131657B2	Bromodomain inhibitors The present invention provides for compounds of formula (I). wherein Rx, Ry, Rx1, L1, G1, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
US10131656B2	Organic thin film transistor, method of manufacturing organic thin film transistor, organic thin film transistor material, organic thin film transistor composition, organic semiconductor film, and compound An object of the present invention is to provide an organic thin film transistor that has an organic semiconductor film manufactured by using a compound having excellent solubility to an organic solvent and that has excellent carrier mobility, a novel compound, an organic thin film transistor material, an organic semiconductor film, an organic thin film transistor composition, and a method of manufacturing an organic thin film transistor using this. The organic thin film transistor according to the present invention has an organic semiconductor film containing a compound represented by Formula (1).
US10131654B2	Pyrazole compounds and methods of use thereof The present invention comprises compounds of Formula I and their use in the inhibition of cell proliferation in therapeutic treatments. Pharmaceutical compositions comprising at least one compound of Formula I and at least one pharmaceutical excipient are disclosed, as well as methods of using compounds of Formula I and pharmaceutical compositions thereof for treatment of hyper-proliferative diseases and other disorders.
US10131653B2	Heterocyclic compound The present invention provide a compound having an orexin receptor antagonistic activity, which is expected to be useful as medicaments such as agents for the prophylaxis or treatment of sleep disorder, depression, anxiety disorder, panic disorder, schizophrenia, drug dependence, Alzheimer's disease and the like.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
US10131652B2	Pyrimidinyloxy benzene derivatives as herbicides Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein Q, Z, R2, R3 and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.
US10131649B2	Bicyclic compounds as pest control agents The present application relates to novel bicyclic compounds, to compositions comprising these compounds, to their use for controlling animal pests and to processes and intermediates for their preparation.
US10131640B2	Anti-inflammatory agents Disclosed are novel compounds that are useful in regulating the expression of interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1), and their use in the treatment and/or prevention of cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s). Also, disclosed are compositions comprising the novel compounds, as well as methods for their preparation.
US10131639B2	Formulations of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4methylcyclohexylamino)-pyrimidine-5-carboxamide Provided are pharmaceutical compositions and dosage forms of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide, or a pharmaceutically acceptable stereoisomer, tautomer, solid form, polymorph, salt, hydrate, clathrate, or solvate thereof. Also provided are methods of treating, managing, or preventing various disorders, such as diseases or disorders treatable or preventable by inhibition of a JNK pathway in mammals using such pharmaceutical compositions or dosage forms. Further provided are salts of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide and methods of preparation of such salts.
US10131633B2	Cationic lipid The present invention provides a cationic lipid which can be used for nucleic acid delivery to a cytoplasm and which is possible to solve the problem of physical stability of a lipid complex. This cationic lipid is a compound represented by the general formula (3) or a pharmaceutically acceptable salt thereof: wherein, L is an alkyl having 7-12 carbon atoms or an alkenyl having 7-12 carbon atoms, R is an alkyl having 1-2 carbon atoms, and n1 and n2 are independently an integer of 1-3.
US10131630B2	Process for preparing (3RS)-3-[(2SR)-(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidinium bromide The present invention relates to an efficient and environmentally friendly process for preparing (3RS)-3-[(2SR)-(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidinium bromide with high yield and purity suitable for industrial scale applications.
US10131628B2	2,2′-diaminobiaryls having a phthaloyl group or succinoyl group An electrochemical treatment of differently protected aniline or napthylamine results in the preparation of unsymmetrical 2, 2′-diaminebiaryls provided with different protecting groups. The treatment involves the protecting groups prior to the C, C coupling step. The co-reactants generally have different oxidation potentials which results from the selection of the protecting groups. The treatment also enables controlled access to the individual amino functions of the 2, 2′-diaminobiaryls by subsequent selective deprotection.
US10131624B2	Process for the preparation of (1S,2R)-Milnacipran The invention relates to a process for the preparation of Levomilnacipran or salts thereof, compounds useful in the treatment of depression, with high yield.
US10131623B2	Process for preparing symmetric pincer ligands from the group of the M-terphenyl compounds The present invention relates to a process for preparing compounds of the formula ABA by reacting a compound of the formula (A) with a compound of the formula (B) with X=—OR′ or —NHR′ and R′=H or a protecting group function and R1, R2, R3, R4, R5, R6, R7 and R8 are each independently selected from the group comprising hydrogen, (C1-C12)-alkyl, O—(C1-C12)-alkyl, (C6-C20)-aryl, O—(C6-C20)-aryl, where two of the R1 to R4 radicals may also be joined via a covalent bond, and halogen, which is characterized in that the reaction is conducted electrochemically.
US10131622B1	N-hydroxyalkylated polyamines, methods of making N-hydroxyalkylated polyamines, and fluids containing an N-hydroxyalkylated polyamine N-hydroxyalkylated polyamines, methods of making N-hydroxyalkylated polyamines, and drilling fluids containing N-hydroxyalkylated polyamines are provided, in which the N-hydroxyalkylated polyamine includes Formula (I): where R1 and R2 are independently a —C or —CH group; R3 is an aliphatic hydrocarbyl; R4 and R5 are independently acyclic hydrocarbyls, or R1, R2, R4, and R5 are covalently connected to form a cyclic hydrocarbyl; and R6, R7, R8, and R9 are independently acyclic hydrocarbyls or acyclic heterohydrocarbyls.
US10131620B2	Process for producing dimethyl carbonate The present disclosure relates to a recycling method for producing dimethyl carbonate and dimethyl carbonate derivatives. The process is unique in that it produces a by-product that can be re-used in the process as a raw material for repeating the process. For example, when the process is directed to synthesizing dimethyl carbonate, glycerol is used as a starting material. Glycerol is also a by-product produced during formation of dimethyl carbonate, and therefore it can be re-used as starting material to generate more dimethyl carbonate.
US10131615B2	Molded catalyst for use in manufacture of methyl methacrylate, and method for manufacture of methyl methacrylate using same The present invention provides a molded catalyst for use in the manufacture of methyl methacrylate, for manufacturing methyl methacrylate from a starting material of methyl α-hydroxyisobutyrate by a vapor phase contact reaction, wherein the molded catalyst for use in the manufacture of methyl methacrylate is characterized in that the molded catalyst includes a synthetic faujasite type zeolite, a lamellar aluminum silicate compound, and a synthetic lamellar magnesium silicate compound, the weight ratio of the lamellar aluminum silicate compound and the synthetic lamellar magnesium silicate compound being 1:5 to 6:1.
US10131607B2	Process for preparing unsymmetric OCO pincer ligands from the group of the M-terphenyl compounds The present invention relates to a process for preparing unsymmetric compounds from the group of the m-terphenyls which can be used as unsymmetric OCO pincer ligands, comprising the process steps of a) reacting a first substituted or unsubstituted phenol with a 1,3-disubstituted arene which may likewise be substituted in the 2 and 5 positions to obtain a phenol-arene coupling product and b) optionally protecting the OH group of the phenol-arene coupling product with a protecting group to obtain a protected phenol-arene coupling product, and c) reacting the phenol-arene coupling product from a) or b) with a second substituted or unsubstituted phenol to obtain an unsymmetric m-terphenyl, with the proviso that the first phenol and the second phenol have different substitution, characterized in that at least one of process steps a) and c) is conducted as an electrochemical process step.
US10131605B2	Tri-substituted aromatic-containing polymeric dispersants Disclosed are novel tri-substituted aromatic-alkoxylated polymeric dispersants and related method of preparing. Also disclosed are methods of dispersing at least one pigment comprising the following steps: contacting an aqueous solution containing at least one pigment with the polymeric dispersant copolymers as described herein.
US10131604B2	Catalysts for hydrodeoxygenation of oxygenated hydrocarbons The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing Group VIII metals. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.
US10131603B2	Method for reducing metal of sugar-alcohol compound and sugar-alcohol compound The present invention provides a method for reducing a metal of a sugar-alcohol compound, the method including the steps of (A) protecting a hydroxyl group of a sugar-alcohol compound containing metal impurities with a protecting group, (B) removing the metal impurities from the sugar-alcohol compound having the hydroxyl group protected with the protecting group, and (C) eliminating the protecting group of the sugar-alcohol compound from which the metal has been removed. There can be provided a method for reducing a metal of a sugar-alcohol compound that can provide a sugar-alcohol compound with a suitable quality for the semiconductor apparatus manufacturing process.
US10131600B2	Process for preparing ethylene glycol from a carbohydrate Ethylene glycol is prepared from a carbohydrate source in a process, wherein hydrogen, the carbohydrate source, a liquid diluent and a catalyst system are introduced as reactants into a reaction zone; wherein the catalyst system comprises a tungsten compound and at least one hydrogenolysis metal selected from the groups 8, 9 or 10 of the Periodic Table of the Elements; wherein the diluent that is introduced into the reaction zone comprises an alkylene glycol; and wherein the carbohydrate source is reacted with hydrogen in the presence of the catalyst system to yield an ethylene glycol-containing product.
US10131599B2	Fracking with CO2 for shale gas reforming to methanol A method of producing methanol from shale gas and CO2 by the exclusive dry CO2 fracking of shale rock by injection of gaseous CO2 at a pressure between 10 and 100 atm to extract shale gas and recover it together with used CO2; combining and admixing produced shale gas containing CO2 and steam to produce a mixture of methane:carbon dioxide:water having a molar ratio of 3:1:2 for conducting the bi-reforming reaction to form a mixture of hydrogen and carbon monoxide having a molar ratio of 2:1 to 2.1:1; and converting the hydrogen and carbon monoxide under conditions sufficient to exclusively form methanol.
US10131598B2	Polyfluoroalkyl allyl compound and method for producing the same A polyfluoroalkyl allyl compound represented by the general formula: CF3(CF2)n(CH2CF2)a(CF2CF2)bCH2CH═CH2 [I] (n: 0 to 5, a: 1 or 2, b: 0 to 3). The polyfluoroalkyl allyl compound is produced by reacting a carboxylic acid allyl adduct represented by the general formula: CF3(CF2)n(CH2CF2)a(CF2CF2)bCH2CHICH2OCOR′ [II] (n, a, and b are as defined above, and R′: a C1-C3 alkyl group) with a transition metal. This method for producing provides a polyfluoroalkyl allyl compound used as a synthetic intermediate for a fluorine-containing alkylsilane compound that can remove free iodine derived from the raw material compound, before a hydrosilylation reaction is performed, without using a metal reagent having a high environmental impact, and that has excellent handling properties.
US10131594B2	Metathesis catalyst on mixed metal oxide-zeolite support and process for use thereof The present invention relates to catalyst comprising at least one transition metal selected from Group VIA and Group VITA metals and a support containing a mixture of 0.1 to 60 percent by weight of zeolite, based on total weight of the support, with at least one other inorganic or organic material, wherein the at least one other inorganic or organic material is selected from silicon dioxide, titanium dioxide, zirconium dioxide and activated carbon, preferably silicon dioxide; and a process for olefin metathesis utilizing that catalyst.
US10131587B1	White smoke mix A mixture and method of creating the mixture includes mixing hexachloroethane, stannous oxide, and aluminum together. The mixture may be loaded into at least one canister. The mixture may be combusted to create a smoke screen. The loading of the mixture into the at least one canister may include pressurized loading at loading pressures in the range of approximately 2300 psi to 3600 psi. The hexachloroethane may include approximately 30-40 parts by weight of the mixture and have a particle size of approximately less than 850 μm. The stannous oxide may include approximately 55-65 parts by weight of the mixture and have a particle size of approximately less than 150 μm. The aluminum may include approximately 5-10 parts by weight of the mixture and have a particle size of approximately less than 45 μm. The mixture is devoid of zinc chloride.
US10131574B2	Antimicrobial glass articles and methods of making and using same Described herein are various antimicrobial glass articles that have improved resistance to discoloration when exposed to harsh conditions. The improved antimicrobial glass articles described herein generally include a glass substrate that has a low concentration of nonbridging oxygen atoms, a compressive stress layer and an antimicrobial silver-containing region that each extend inward from a surface of the glass substrate to a specific depth, such that the glass article experiences little-to-no discoloration when exposed to harsh conditions. Methods of making and using the glass articles are also described.
US10131573B2	3-D glass enclosures for electronic devices A 3-D glass enclosure comprises a generally planar glass base member, an encircling glass side wall member connected to the base member, and a generally planar glass cover member connected to the side wall member to form a unitary glass enclosure, the base, sidewall and cover members being made by reforming softened glass sheet preforms and subjecting the reformed members to ion-exchange strengthening, thus providing strong transparent enclosures for electronic devices such as tablet computers, cellphones, media players and televisions.
US10131571B2	Methods of forming optical system components and optical coatings A method of forming an optical coating, including the steps: depositing a buffer layer on a glass substrate via plasma deposition at a first plasma bias voltage; and depositing at least one layer of an optical coating on the buffer layer via plasma deposition, the deposition of the optical coating carried out at a second plasma bias voltage.
US10131570B2	Liquid-based masking layer A method of fabricating a liquid-based masking layer for a wet etching process, is disclosed. The method comprises forming a coated solid substrate by coating a solid substrate with a coating; forming a preliminary masking layer by removing parts of the coating which are not included in a pattern; depositing a porous surface on the preliminary mask to obtain a porous preliminary mask; forming a liquid-based masking layer by filling the pores of the porous preliminary mask with a filling liquid; and applying an etchant to a surface of the solid substrate and the liquid-based masking layer, etching parts of the substrate that are not covered with the liquid-based masking layer.
US10131569B2	Method for the preparation of lithium silicate glasses and lithium silicate glass ceramics The invention relates to a method for the preparation of a lithium silicate glass or a lithium silicate glass ceramic which comprise cerium ions and are suitable in particular for the preparation of dental restorations, the fluorescence properties of which largely correspond to those of natural teeth.The invention also relates to a lithium silicate glass and a lithium silicate glass ceramic which can be obtained using the method according to the invention, the use thereof as dental material and in particular for the preparation of dental restorations, as well as a glass-forming composition which is suitable for use in the method according to the invention.
US10131565B2	Preform for an optical waveguide and a fiber with non-circular core Preform for an optical waveguide containing a core with a non-circular geometry and at least one cladding layer, in which the dopand concentration of the cladding layer is increased compared to the dopand concentration of a preform with circular core geometry and identical NA. A method for the production of a preform for an optical fiber is provided. An optical waveguide with a nominal dopand concentration of c(eff)×F≤c(nom) in at least one cladding layer is also provided.
US10131562B1	Treatment of potable water Methods and systems for treating water for potable use or consumption are described. In an embodiment, a method for treating water for potable may include adding an effective amount of a magnesium compound to supply water to be treated. The method may also include adding an effective amount of a flocculation aiding metal salt to the supply water. The method may further include removing one or more contaminants from the supply water to provide treated water. Other methods and systems are described.
US10131559B2	Dual media system for treating wastewater containing selenium A bioreactor has a biofilm supporting bed with at least two types of media. An upper media is relatively porous, preferably porous enough to admit particles of a lower media. In use, wastewater flows downwards through the bed. Soluble nitrogen is reduced in the upper media and converted into nitrogen gas. Nitrogen gas bubbles rise through the upper media and escape from the bed. Selenium is reduced in the lower media and converted into elemental selenium. The elemental selenium is released periodically by backwashing the bed, which may cause fluidization or other expansion of the lower media into the upper media.
US10131557B2	Process for treatment of a fluid comprising an oxidizable containment There is described a process for treatment of a fluid comprising an oxidizable contaminant. The process comprises the step of contacting the wastewater with a combination of: (i) a sulfide, (ii) a complex of Fe(III) and a chelating agent, and (iii) an oxidant. It has been discovered that of treatment of a fluid containing an oxidizable contaminant employing iron(III)-chelates as the Fenton catalyst may be significantly improved by including a sulfide in the reaction scheme. As described herein, by employing sulfide ion, the present inventors have been able to: (i) increase the rate of iron recycling from minutes or hours to a few seconds, and (ii) destroy benzene in an oil and gas refinery (OGR) wastewater in less than one minute. It is believed that these findings in OGR wastewater can be extended to other fluids containing other oxidizable contaminants.
US10131555B2	Method and apparatus for controlling concentration of free chlorine, and sterilization method and sterilization apparatus each utilizing said method and said apparatus The method includes a process of (i) and a process of (ii) in this order. In the process of (i), the potential of a first anode and the potential of a first cathode are adjusted in an aqueous solution containing chloride ions so as to increase the concentration of free chlorine in the aqueous solution. In the process of (ii), the potential of a second anode and the potential of a second cathode are adjusted in the aqueous solution so as to decrease the concentration of free chlorine in the aqueous solution. The difference between the potential of the second anode and the potential of the second cathode in the process of (ii) is smaller than the difference between the potential of the first anode and the potential of the first cathode in the process of (i).
US10131554B2	Mobile water cart with water pre-conditioning device Water supply vehicle comprising a water reservoir, a flow through descaling device having a water inlet, a water outlet, a detecting device for detecting a water characteristic in a water flow from the water inlet to the water outlet, a controllable water descaling device, and a controlling device being designed for controlling the water descaling device based on a water characteristic detected by the detection device, wherein the water reservoir is connected to the water inlet, wherein the water outlet is connectable to a water hose for supplying water to a water consumer.
US10131551B2	Separation of kinetic hydrate inhibitors from an aqueous solution The invention relates to a process for treating an aqueous solution from a subterranean formation of an oil and gas operation. The aqueous solution can be removed from the subterranean formation and treated in a heated centrifugal separator. The heated centrifugal separator can separate the kinetic hydrate inhibitor from the aqueous solution, and then the aqueous solution can be reintroduced into the subterranean formation.
US10131548B2	Modification of layered double hydroxides The present invention relates to a process for modifying a layered double hydroxide (LDH), the process comprising, a. providing a material comprising a layered double hydroxide of formula: [Mz+1-xM′y+x(OH)2]q+(Xn−)q/n.bH2O wherein M and M′ are metal cations, z is 1 or 2, x is 0.1 to 1, b is 0 to 5, y is 3 or 4, X is an anion, n is 1 to 3 and q is determined by x, y and z, b. optionally washing the material at least once with a mixture of water and a mixing solvent miscible with water, and c. washing the material obtained in step a or b at least once with at least one first solvent, the first solvent being miscible with water and having a solvent polarity P′.
US10131544B2	Graphene/porous iron oxide nanorod composite and manufacturing method thereof The present invention discloses a graphene/porous iron oxide nanorod composite and a method for preparing the same. The composite includes graphene and Fe2O3 nanoparticles loaded on the graphene. The Fe2O3 nanoparticles have a honeycomb porous structure. The synthesis method of the composite is simple and the raw materials are inexpensive.
US10131543B2	Method for producing porous calcium deficient hydroxyapatite granules The method is for producing porous calcium deficient hydroxyapatite granules and comprises the following steps: (a) subjecting granules of calcium sulfate anhydrous (CSA), calcium sulfate dihydrate (CSD) or calcium sulfate hemihydrate (CSH), the granules comprising interconnected pores with a minimum mean diameter of 3 microns, to a first incubation in an alkaline aqueous solution having a pH-value of less than 10 and containing PO43− ions; (b) subjecting the granules to a second incubation in an alkaline aqueous solution having a pH-value of more than 10 and optionally PO43− ions; (c) filtering and drying the obtained porous granules of calcium deficient hydroxyapatite; and wherein (d) the sum of the amounts of PO43− ions present in the first and second incubation is at least as large as the amount of SO42− ions of the granules used for step (a). The porous calcium deficient hydroxyapatite granules obtained by the invention may be purposefully used as carriers for biologically active substances in particular for proteins.
US10131534B2	Stacked vias for vertical integration This disclosure provides systems, methods and apparatus for a via structure. In one aspect, an apparatus includes a substrate and a first electromechanical systems device on a surface of the substrate. The first electromechanical systems device includes a first metal layer and a second metal layer. A first via structure can be included on the surface of the substrate. The first via structure includes the first metal layer, the second metal layer, and a third metal layer. The first metal layer of the first electromechanical systems device may be the same metal layer as the first metal layer of the first via structure.
US10131532B2	Electronic vaporiser system An e-liquid cartridge designed to provide e-liquid for an electronic cigarette vaporizer system, the cartridge including a chip that stores and outputs (i) a unique identity for the cartridge and/or (ii) data defining the e-liquid stored in the cartridge, and the cartridge being adapted to be inserted into or form an integral part of the electronic vaporizer system. The data stored and output by the chip defines one or more of: flavor, nicotine strength, manufacturing batch number, date of manufacture, date of filling, tax data, quantity of e-liquid stored in the cartridge.
US10131528B2	Flavoring dispensing apparatus, system and method A flavoring dispensing apparatus, system, and method configured for use with a plurality of pump equipped flavoring containers such as bottles, operable to automatically dispense relatively precise or metered amounts of flavoring, and more specifically concentrated flavoring, into a beverage container, mixing vessel, or other receiver. The containers are easily removed and replaced and flavoring levels can be automatically monitored for replacement with a fresh container.
US10131526B2	System and method for filling containers An apparatus for filling containers with a liquid filling material includes a container treatment unit, a weighing unit, container carriers, weighing cells, a conveying element, filling positions, container receptacles, and a container-conveying section. As the conveying element, on which the filling positions are formed, rotates, it introduces filling material into the containers. The conveying element includes the container-conveying section, which moves the containers in a container-conveying direction. The weighing unit, which is made in the conveying element, weighs containers on the container-conveying section. Each container receptacle forms a weighing position with an associated container carrier and weighing cell.
US10131524B2	Gear reduction assembly and winch including gear reduction assembly A gear reduction assembly may include a main input shaft, a carrier coupled to the main input shaft, and at least one carrier shaft coupled to the carrier and spaced from the main input shaft. The gear reduction assembly may also include at least one spur gear pair including a first spur gear coupled to the carrier shaft, and a second spur gear, wherein the first and second spur gears are coupled to one another such that they rotate together. The gear reduction assembly also includes a first internal gear engaged with the first spur gear, a second internal gear engaged with the second spur gear, and a hub associated with the first internal gear. The first internal gear has a first number of teeth, the second internal gear has a second number of teeth, and the first and second numbers of teeth differ by from one to five teeth.
US10131514B2	Support mechanism for processing unit in sheet processing device The present invention is to provide a processing unit which can move smoothly to accurate position in a proper posture. The processing unit is provided with a support mechanism that supports a processing unit 26 so as to allow the processing unit 26 to be moved to a sheet processing position (processing tray) 24. The support mechanism includes the processing unit 26 and first and second support portions 50 and 55 that support the processing unit 26. The first and second support portions 50 and 55 apply, to different positions (j and k) of the processing unit 26 which are spaced from each other, a support force Fa acting from below to above (in a direction opposite to a gravity acting direction) and a support force Fb acting from above to below (in a direction same as the gravity acting direction), respectively.
US10131513B2	System and method of automatic feeder stack management Embodiments of a system and method for singulating articles in an automatic stack feeder are disclosed. The automatic stack feeder may comprise a pressure sensor on a perforated drive belt assembly configured to sense the pressure exerted by a stack of articles. The sensed pressure may be used to control various portions of the automatic stack feeder, such as a belt or a paddle.
US10131512B2	Document feeder and image forming apparatus incorporating the document feeder A document feeder, which may be incorporated in an image forming apparatus, includes a sheet conveying guide, at least one recess, a frame, and at least one protrusion. The sheet conveying guide is disposed facing an exposure glass on an apparatus body and guides an original document passing over the exposure glass when the document feeder is closed to the apparatus body. The recess is disposed on the apparatus body at both ends of the exposure glass in a lateral direction orthogonal to a document conveying direction. The frame is openably closable about one end side of the apparatus body in the lateral direction and vertically movably holds the sheet conveying guide. The protrusion is disposed on the frame facing the recess. The sheet conveying guide and the frame are secured to each other while the recess and the protrusion are engaged with each other in the closed state.
US10131510B2	Draw-in device for sheet-type articles A draw-in apparatus having at least two rotatable draw-in rollers for drawing in sheet goods, in particular bank notes, wherein the draw-in rollers are arranged relative to each other with meshing roller profiles respectively extending transversely to the draw-in direction so as to define a draw-in gap for the sheet goods, and wherein the draw-in rollers have axial cross-sectional profiles mutually matched such that a clearance between the draw-in rollers changes periodically upon a rotation of the draw-in rollers.
US10131507B1	Ejector hood An ejection hood apparatus includes a transfer conduit and a hood. The transfer conduit includes a downwardly concave control shell. An inlet end portion of the transfer conduit receives an upwardly directed transfer air stream including ejected material with at least a partially upward trajectory. The hood defines an ejection chamber including a lower chamber portion and an upper chamber portion. The lower chamber portion receives the transfer air stream from an outlet end portion of the transfer conduit with at least a partially downward trajectory. The hood includes at least one air outlet passage communicated with the upper chamber portion for exhausting at least a portion of the transfer air stream.
US10131506B2	Selective matrix conveyance apparatus and methods for granular resin material An apparatus for conveying granular resin material from one or more supplies to a receptacle adjustably selected from a plurality of receptacles.
US10131502B2	Front and/or side mount motor A conveyor system comprising: (a) one or more frames; (b) one or more controllers; (c) one or more motors located within a motor housing; and (d) a plurality or rollers; wherein the motor housing includes one or more internal pockets that receive the motor and the one or more controllers, and the controller is in contact with one or more walls of the motor housing; and wherein the motor housing is directly connected to the frame so that at least one of the one or more walls in contact with the controller are in direct contact with the one or more frames.
US10131501B1	Chain guide for paddle-type conveyor A guide that fits over a paddle link in a paddle-type elevator in a harvester combine grain elevator. The plastic guide provides a wide, low-friction surface that rides on the intermediate wall of a grain elevator, thereby keeping the paddle links from rubbing against and causing wear to the intermediate wall. The guide also serves to inhibit the paddle from tipping back, thereby preventing the concentration of force by one corner of a paddle link against the intermediate wall. The guide al so helps maintain the correct orientation of flexible paddle against the inside of the elevator housing, thereby inhibiting the paddle from tipping back and leaking grain back into the upward path of the conveyor. The plastic guide also reduces noise caused by the metal parts of a paddle-type elevator from coming into contact.
US10131489B2	Carrier for a container for rod-like articles of the tobacco industry A carrier for a container for rod-like articles of the tobacco industry, the carrier interior having a cuboid-like shape, the carrier having a bottom wall, a middle sidewall and two outer sidewalls=adjoining it, while from the side of the remaining walls of the abovementioned cuboid the carrier is open. An external movable element is attached to the carrier and extending along the middle sidewall. The height of the middle sidewall is lower than the height of the outer sidewalls, so that between the outer sidewalls and the upper edge of the middle sidewall there is a void space. The movable element is movable between a first position, in which it lies opposite to the middle sidewall, and a second position, in which it lies at least partially opposite to the void space or at least partially is situated within the void space above upper edge of the middle sidewall.
US10131484B2	Containers and methods for isolating liquids prior to dispensing A container (100) for isolating first and second fluids, such as beverage concentrate components, until dispensing is provided, as well as methods of assembly and dispensing. The container can have first (111) and second (113) enclosed bodies for containing the first and second fluids to be dispensed and an insert (130) directing fluid from the enclosed bodies, such as toward one or more valves or separate discharge paths (148a, 148b).
US10131482B2	Antimicrobial packaging material A packaging material includes an antimicrobial agent adhered to a substrate. The antimicrobial agent can include copper, and the packaging material can include cellulose. The substrate can be paperboard, and the copper can be a copper salt, such as copper sulfate. The packaging material may be provided by causing adherence between the substrate and the antimicrobial agent, such as by coating the substrate with the antimicrobial agent. Then, the packaging material may be cut into sheets. The sheets may be formed into cartons or other suitable packages.
US10131481B2	Oxygen absorbing multilayer container and method for producing the same An oxygen absorbing multilayer container having at least three layers of a first resin layer containing a thermoplastic resin, an oxygen absorbing layer containing an oxygen absorbing resin composition which contains a polyester compound (a) containing a constituent unit having a tetralin ring and a transition metal catalyst, and a second resin layer containing the same type of thermoplastic resin as the thermoplastic resin contained in the first resin layer, in this order, in which a cycloolefin polymer having a glass transition temperature of 50 to 110° C. is contained as the thermoplastic resin.
US10131476B2	Child safety covers for use with various packaging or containers including without limitation packaging and containers shaped to correspond to a characteristic of the contents contained therein Various shaped packaging containers for storing liquids and/or solid contents. In one embodiment, the container can have a leaf shaped body member. The body member can be opaque or transparent. A base member can be secured to a bottom area of the container. The base can be solid or can be provided with a lid opening at the bottom to provide access to the contents contained within the leaf shaped body member. The lid can be pivotally secured to the base. In a preferred embodiment a novel child safety lid/cover is provided and used to close the opening for the container. The cover requires a multiple step process in order to be removed and helps to prevent inadvertent or accidental openings of the container.
US10131466B2	Active electronic media device packaging Active packaging for supplying power, data, or both power and data to an electronic media device while the device is housed within the active packaging is provided. The active packaging may include one or more electrical traces in-molded or printed onto the packaging that couple to a suitable connector on the device. Power may also be provided via one or more wireless power techniques. Multiple active packages may be conductively stacked to transmit power, data, or both power and data to a row or stack or devices. POM sensors integrated with or attached to the device (or the active packaging itself) may detect various movement events. Coordinated and synchronized display effects may be presented while the devices are housed within the active packaging.
US10131465B2	Container with removable tray The present invention relates to a container including a container body with a removable tray wherein the container can house at least two materials that must be kept separate until use. The container also may have upwardly extending fingers in the removable tray for securing a material.
US10131464B2	Container for foodstuffs, in particular coffee A container for foodstuffs (10), in particular coffee, suitable to be used as a refill for a tin (20) having a peripheral wall (21) made of rigid material, which defines an internal compartment (22), comprises a central body (11) made of a flexible material and having external sizes substantially equal to, or a little smaller than, those of said internal compartment (22) of the tin (20). Coupling means (30) are provided to temporarily couple, in a removable manner, the central body (11) with the tin (20).
US10131452B1	Integrated telescopic boom and large deployable reflector A telescopic boom and reflector assembly for a spacecraft that includes a telescopic boom having a plurality of boom sections that are nested together within a prime batten or where the prime batten is attached to an outermost section of the boom when the boom is in a stowed position, where an innermost and smallest diameter section of the boom is secured to the spacecraft to facilitate testing and integration of the boom and reflector as a unitized assembly. The assembly also includes a reflector having a truss structure configured to allow the reflector to be collapsed into a stowed configuration, where the reflector is mounted to the prime batten. The assembly is configured to be deployed from the spacecraft by releasing the boom in a telescopic manner where the boom sections increase in diameter from the spacecraft outward when the boom is deployed.
US10131451B2	Pre-flight self test for unmanned aerial vehicles (UAVs) In one embodiment, a controller instructs an unmanned aerial vehicle (UAV) docked to a landing perch to perform a pre-flight test operation of a pre-flight test routine. The controller receives sensor data associated with the pre-flight test operation from one or more force sensors of the landing perch, in response to the UAV performing the pre-flight test operation. The controller determines whether the sensor data associated with the pre-flight test operation is within an acceptable range. The controller causes the UAV to launch from the landing perch based in part on a determination that UAV has passed the pre-flight test routine.
US10131445B2	Containment system and increased strength radome assembly A containment system for containing all or part of a radome and an external subassembly that is protected by the radome is disclosed. One embodiment of the containment system comprises a fabric material and an attachment system for attaching the fabric material to the radome and to the radome attachment ring. An increased strength radome for covering the external subassembly is also disclosed.
US10131444B1	System and method of providing clipboard cut and paste operations in an avionics touchscreen system A keyboard module configured for use in an avionics touchscreen system is disclosed. The keyboard module is configured to display, via a visual display in the avionics touchscreen system and responsive to a selection of an application program generated widget for focus via a touchscreen surface in the avionics touchscreen system, a virtual keyboard. The virtual keyboard includes a text box widget configured to display clip data stored in clipboard memory provided by the avionics touchscreen system, a copy widget configured to cause data in a first widget provided by the application program that is in focus to be copied to the clipboard memory, and a paste widget configured to cause the clip data in the clipboard memory and displayed in the text box widget to be pasted to a second widget provided by the application program that is in focus.
US10131442B2	Power leveling controller The disclosure herein relates to power leveling mechanisms comprising a high frequency controller. The power leveling mechanism receives a power demand signal indicating a power requirement of a vehicle and determines a high frequency component of the power demand signal. The power leveling mechanism also provides a signal to a primary propulsion system and provides, via the high frequency controller, a high bandwidth signal based on the high frequency component to an auxiliary propulsion system.
US10131439B2	Ejection seat pan lifter An aircraft is provided and includes a fixed frame including a ledge and a seat pan on which seating elements for seating an aircraft crewperson are disposable. The seat pan includes a hinge about which the seat pan is pivotable relative to the fixed frame and a flange disposable on the ledge to establish a first pivot position for the seat pan relative to the fixed frame and a seat pan lifter coupled to the fixed frame and selectively interposable between the flange and the ledge to establish a second pivot position for the seat pan relative to the fixed frame.
US10131438B2	Ejector seat with ejection retracting backrest An aircrew member must be properly positioned during flight to have a view inside and outside of the cockpit and to reach all aircraft controls. However, if an ejection event occurs, the aircrew member should be properly aligned with a thrust direction of the ejection seat to prevent injury. A retracting backrest for an ejection seat is deployed pre-flight to a desired flight position. A release mechanism engages a positioning member to secure the retracting backrest in the flight position. In response to an eject signal, the release mechanism disengages from the positioning member, and both the aircrew member and the retracting backrest are hauled back to properly align the aircrew member for ejection.
US10131437B1	Aerial package delivery system Systems and methods for delivering packages via aerial vehicles are disclosed. The system can comprise a label that includes a parachute to enable the packages to be dropped from the aerial vehicle, yet land at the package's destination without damage. The system can include a self-adhesive backing, a plurality of parachute cords, a parachute, and a breakaway cover. The parachute cords can include a shock absorber to reduce the shock on the package of the parachute opening. The parachute and/or the breakaway cover can include graphics to provide address, velocity, or spin information for the package. The parachute cords can include a harness to separate the cords and reduce tangling of the cords and spinning of the parachute canopy with respect to the package.
US10131436B1	Conductive network for parachute fabrics An apparatus, method for making, and product by process for a parachute, the parachute having a conductive network and a set of fabrics; the conductive network including a set of conductive elements and a set of devices; wherein a first subset of conductive elements of the set of conductive elements is incorporated with a second subset of fabrics of the set of fabrics and third subset of devices of the set of devices incorporated is incorporated with a fourth subset of fabrics of the set of fabrics.
US10131434B2	Cooling assembly for an aircraft provided with a fan A cooling assembly (15) includes a conduit (16) including a side wall (17) and a fan (20) that includes a rotating electric machine (32), a power supply module (35) including three distinct single-phase self-transformers (79a, 79b, 79c), each single-phase self-transformer being magnetically decoupled from one another, each single-phase self-transformer (79a, 79b, 79c) surrounding the side wall (17) of the conduit.
US10131432B2	Privacy divider for adjacent parallel passenger seats A suite divider for a passenger suite seating arrangement including separate first and second panels adapted to be deployed along a top of a partition wall separating laterally adjacent passenger suites, the first and second panels adapted to be stowed near respective first and second ends of the partition wall to connect the laterally adjacent passenger suites, and horizontally driven together to separate the laterally adjacent passenger suites.
US10131430B2	Rapid store load system for aircraft and method of operation thereof A method to load stores on an aircraft, the method may be controlled by one or more controller and may include one or more acts of loading stores onto corresponding lift portions; determining a relative position of the aircraft; positioning the stores relative to the determined position of the aircraft; and securing the stores to corresponding hardpoints (HPs) of the aircraft.
US10131429B2	Method and systems of autonomously picking up water in support of fire fighting missions The disclosure is directed to systems and methods for autonomously picking up water in support of fire fighting missions using aerial vehicles. More particularly, the disclosure is directed to systems and methods for picking up water in support of fire fighting missions using onboard sensing and decision making processes with application of the fire retardant using unmanned aerial vehicles.
US10131428B1	Inflatable packaging for use with UAV An inflatable package enclosure for use on an aerial vehicle including an inflatable exterior chamber, a first inner cavity positioned within the inflatable exterior chamber, an inflation valve positioned on the inflatable exterior chamber, and a handle on the inflatable exterior chamber for securing the inflatable package enclosure to the aerial vehicle, wherein when the inflatable exterior chamber is inflated and when a package is positioned in the first inner cavity, inner surfaces of the inflatable exterior chamber conform to outer surfaces of the package to secure the package within the inflatable exterior chamber.
US10131425B2	Rotary wing aircraft having a non-ducted tail rotor with at least five blades A non-ducted tail rotor comprising a hub and at least five blades, each of the blades extending to a free end that, in rotation, describes a circle presenting a given “maximum” radius. The hub is rigidly secured to a drive shaft, the hub comprising a hollow circular body centered on an axis of rotation, the body presenting an “internal” radius between the axis of rotation and an outer periphery of the body, the internal radius lying in the range 0.2 times to 0.4 times the maximum radius, each blade presenting a root extended by an airfoil element projecting from the body, extending from the root to the free end, the root being swivel-hinged to the outer periphery about a pitch axis.
US10131422B2	Aircraft An aircraft includes: a plurality of rotor units each including a propeller and a motor that drives the propeller; and a shock absorber covering the entire vertical length of lateral sides of the plurality of rotor units.
US10131421B2	Locked wheel extension protection in brake control systems A method for controlling brakes is provided. The method may include the steps of detecting an aircraft speed, determining the aircraft speed is within a range from an antiskid-dropout speed to a locked-wheel-protection-engagement speed, and determining an input of a pressure controller has a value less than a pressure maximum threshold. A current command that is output from the pressure controller may be detected at or above a threshold value. The states of the pressure controller and pressure controller input may be reset in response to the current command being at or above the threshold value for a predetermined duration.
US10131419B2	Systems and methods for detecting landing gear ground loads There is provided a system for predicting loading of a landing gear including, a plurality sensors positioned proximate to the landing gear. The plurality of sensors measure strain applied to the landing gear, and each sensor yielding strain data. The system further includes a processor that receives the strain data from the plurality of sensors and predicts at least one ground load based on strain data. There is further provided a method for predicting loading of a landing gear. The method includes powering a plurality of sensors located proximate to a landing gear structure, interrogating the plurality of sensors via data acquisition circuitry to yield strain data, instructing the data acquisition circuitry as to a sampling rate and data resolution to be used for the interrogating, and, finally, processing the strain data to predict a ground load.
US10131414B2	Shipboard auditory sensor A Shipboard Auditory Sensor (SAS) for detection and classification of acoustic signaling at sea is capable of detecting whistles blasts from other vessels in accordance with Rules 34 and 35 of COLREGS to support autonomous operations in a maritime environment.
US10131389B1	Automated guided cart independent securing device A workpiece transport assembly, a material handling assembly and a method of operating a cart within a material handling environment. An automated guided cart includes two independently-operable workpiece-securing devices to selectively permit retention of a workpiece or a workpiece-holding pallet while disposed on a mounting surface of the cart. The second workpiece-securing device is mounted to the cart in such a way as to be cooperative with the mounting surface to selectively permit workpiece or pallet retention regardless of whether the first workpiece-securing device is securing the workpiece to the cart. The second workpiece-securing device may be actuated either manually by operational personnel or automatically by controller or in response to movement by a cooperating conveyor.
US10131387B2	Construction vehicle having a tippable chassis A construction vehicle has a slewing ring on which a superstructure is rotatably mounted, and an undercarriage supporting the slewing ring. The undercarriage includes an upper chassis, having an upper propulsion device, that is rigidly connected to the slewing ring, and a lower chassis having a lower propulsion device that is mounted in a pivotable manner with respect to the upper chassis. Furthermore, a pivoting apparatus is provided in order to pivot the lower chassis relative to the upper chassis.
US10131385B2	Aerodynamic device An aerodynamic device provided as a plate-shaped body attached to a roof or a side wall of a vehicle includes means configured to selectively raise ribs arranged in two directions from a surface portion of the plate-shaped body in a switching manner between the two directions.
US10131381B2	Joint for an underbody of a motor vehicle A joint for a vehicle can direct forces away from an interior of the vehicle and along a frame rail. The joint can pivot when subjected to a high force, and the pivoting action can redirect and redistribute the force away from a passenger compartment. The joint can comprise multiple pivot points.
US10131378B2	Electric power steering apparatus An electric power steering apparatus which has a steering torque sensor to detect a steering torque, a current command value calculating section to calculate a current command value based on the steering torque, a motor to apply an assist torque, and a motor driving control section to drive and control the motor, comprises: a control function with an input steering angle; and a steering angle estimating/calculating section to calculate a front-wheel estimated steering angle and a rear-wheel estimated steering angle based on a 4 wheel speeds and calculate a 4-wheel estimated steering angle. The 4-wheel estimated steering angle is used for a steering angle control.
US10131370B1	Cart for protected transport of vulnerable artwork and method A cart is conveniently loaded and unloaded for protected transport of vulnerable artwork of larger dimensions. A cage located at the top of the cart includes perimetric members that confine the artwork safely during transport. One of the perimetric members is selectively removable for opening the cage to admit and release the artwork into and out of the cage through a corresponding side of the cage, thereby avoiding lifting of the artwork vertically over the cage during loading and unloading of the artwork transported by the cart.
US10131363B2	Vehicle with mode guidance A vehicle includes: a motor, sensors, steering, a suspension, a terrain mode switch, processor(s) configured to: implement a selected terrain mode by tuning at least one of the motor, steering, and suspension; record selected terrain modes; compute a confidence factor based on the recorded selections; determine a road condition based on the sensors; display guidance based on the confidence factor and the road condition.
US10131353B2	Vehicle and method for controlling the same A vehicle chooses a target vehicle based on a position of a preceding vehicle and information about a visual line of a driver, both of which are acquired by respective detection units provided in the vehicle, and controls a traveling speed of the vehicle of the driver in relation with the target vehicle. The vehicle includes: a preceding-vehicle detection unit to detect other vehicle located in front of the vehicle of a driver to acquire a position of the other vehicle; a driver visual line detection unit to acquire information about a visual line of the driver; and a control unit to choose a target vehicle based on the information of the other vehicle and the information about the visual line of the driver and control a traveling speed of the vehicle which the driver drives such that an inter-vehicle distance from the target vehicle becomes a preset distance.
US10131352B2	In-vehicle electric motor control device A CPU drives an inverter based on a command rotation speed that is inputted from a higher level ECU at a predetermined update interval. The CPU acquires an actual rotation speed of the electric motor, and calculates an accelerated rate and a decelerated rate based on the update interval and a difference between the actual rotation speed and the command rotation speed such that the actual rotation speed changes without reaching the command rotation speed and becoming constant before an end of the update interval. The CPU drives the inverter such that the electric motor rotates at the calculated rate.
US10131350B2	System and method of a velocity control mechanism for a vehicle A velocity control mechanism for a vehicle operable to move in a forward direction and a rearward direction. The velocity control mechanism includes an acceleration control mode operable to accelerate the vehicle in one of the forward direction and the rearward direction, a velocity control mode operable to control a velocity of the vehicle in one of the forward and the rearward direction, and an intermediate control mode positioned between the acceleration control mode and the velocity control mode. An actuator is moveable between the acceleration control mode and the velocity control mode and is biased into the intermediate control mode.
US10131343B2	Hybrid vehicle A vehicle includes an engine, an MG (motor generator) an MG2, a planetary gear device mechanically coupled to the engine and MG1 and MG2, a battery, an inverter configured to perform a power conversion between the battery and MG1 and between the battery and MG2, and a controller. MG1 generates a counter-electromotive torque when rotated by the engine. During an inverter-less running control where the inverter is put into a gate shut-off state and the engine is driven to cause MG1 to generate the counter-electromotive torque, the controller decreases a engine target rotation speed Netag when an integrated value of battery charging current (deterioration evaluation value D) is greater than a predetermined value (threshold value D1) smaller than the engine target rotation speed Netag when the deterioration evaluation value D is equal to or smaller than the threshold value D1.
US10131342B2	Engine friction model adaptation A hybrid powertrain includes an engine having a crankshaft and a throttle body, and an electric machine having a rotor selectively coupled to the crankshaft via a disconnect clutch. A transmission of the powertrain includes a torque converter having an impeller fixed to the rotor, a turbine disposed on an input shaft of the transmission, and a bypass clutch configured to selectively transmit torque from the impeller to the turbine. A vehicle controller is programmed to, in response to the bypass clutch being open or slipping and the disconnect clutch being closed, command a throttle position of the throttle body based on an error between measured and estimated speeds of the impeller.
US10131338B2	Heat-exchange dryer apparatus, system and method Various embodiments of a heat-exchange dryer apparatus are disclosed. In one embodiment, a heat-exchange dryer apparatus includes a desiccant cartridge comprising desiccant material, a purge-air reservoir secured to the desiccant cartridge, and a compressed-air conduit disposed inside the purge-air reservoir. In another embodiment, a vehicle air-brake system includes an air compressor, a desiccant cartridge comprising desiccant material, and a heat exchange dryer apparatus disposed between the compressor and the desiccant. The temperature of the compressed air is decreased while the temperature of the purge air is increased and the desiccant adsorbs a greater amount of contaminants form the compressed air for improved drying.
US10131337B2	Relay valve module of a pneumatic brake system A relay valve module of a pneumatic brake system for a vehicle includes a relay valve and an actuating unit. A valve body of the relay valve defines therein an air supply chamber in fluid communication with a supply air reservoir, and a delivery chamber in fluid communication with brake cylinders. A valve seat is disposed between the air supply and delivery chambers; and is opened and closed by movement of a valve member that is actuated by a piston slidable relative to the valve body. The actuating unit includes a stem assembly moved by a pressure to press the piston so as to move the valve member, and an actuating assembly electrically connected with an electronic control unit of the vehicle to receive a brake signal therefrom to provide the pressure to the stem assembly.
US10131336B2	System and method for braking a vehicle A valve includes at least one of an electrical port adapted to receive an electronic control signal and a pneumatic control port adapted to receive a pneumatic control signal. The valve also includes a pneumatic delivery port. The pneumatic delivery port is adapted to transmit a pneumatic fluid, based on the at least one of the received electronic control signal and the received pneumatic control signal, from a second independent source to control i) a second associated service brake and ii) delivery of the pneumatic fluid from a first independent source to control a first associated service brake.
US10131333B2	Brake actuation unit A brake actuation unit (1) having a master brake cylinder (2) and a pressure-medium reservoir (4); a pressure provision device (5), having a piston (51) actuated by an electric motor (35), wherein the piston delimits a pressure chamber (50); first and second groups of electrically actuatable valves (6a-6d, 7a-7d); and an electronic control unit (12, 12′). The electric motor has at least two independently operable drive units, each having at least one winding, for driving the electric motor. The electronic control unit has a first microcontroller (201) and a second microcontroller (301). The first microcontroller controls (205) one of the drive units and the second microcontroller controls (305) the other of the drive units. The first and second microcontrollers control (207, 307) the second group of valves.
US10131328B2	Automatic wheel chocking system for vehicles A wheel chocking assembly for a vehicle such as a truck where the wheel chocks are supported in respective cradles mounted for rotation on the truck's frame or chassis, and where the cradles are adapted to be moved between a first upwardly-facing inoperative position where each cradle supports its corresponding chock in an inoperative mode, and an operative positon where each cradle is rotated about 180° sufficient to lower its corresponding chock by a tether into chocking position under the influence of gravity. A control system is provided where transition from the aforementioned inoperative position to the operative position is remotely controlled by operation of the vehicle's parking brake.
US10131323B1	Vehicle notification system for approaching object detection A notification system for a vehicle is disclosed. The system comprises at least one object detection sensor configured to detect an object proximate to the vehicle and communicate a distance signal indicating a distance of the object from the vehicle. The system further comprises a first notification device configured to output a vibrating notification and a controller in communication with the at least one object detection sensor and the first notification device. The controller is configured to identify a first object detection of the approaching object in response to the distance signal indicating that the distance of the object is less than a first predetermined distance. The controller is further configured to activate the first device to output the vibrating notification in response to the first object detection.
US10131316B2	Airbag and method for operating a vehicle occupant protection system In an airbag comprising at least one aperture (14) which is provided in an airbag shell (12) and to which a closure element (16) is attached a tether (34) via which the closure element (16) can be maintained in a closed position acts on the closure element (16). The invention moreover relates to a method of operating a vehicle occupant protection system.
US10131313B2	Inflatable curtain restrictor An apparatus (10) for helping to protect an occupant (28) of a vehicle (12) includes an inflatable vehicle occupant protection device (14) configured to be inflated and deployed between a side structure (16) of the vehicle and the vehicle occupant. A deployment sleeve (50) encircles a portion of the protection device. The deployment sleeve (50) includes a rupturable tear seam (54) that absorbs the initial break-out forces of the protection device (14) during the initial stages of inflation and deployment. The tear seam (54) is adapted to rupture after the deployment sleeve (50) absorbs the break-out forces and release the protection device (14) to inflate and deploy to a fully inflated and deployed condition.
US10131310B2	Side airbag device for vehicle A seat provided in a vehicle interior of the vehicle; a side airbag having a plurality of chambers each folded, the side airbag being stored in a side portion of a seat back; an inflator arranged together with the side airbag, the inflator suppling gas to the plurality of chambers when a side-impact crash of the vehicle is detected; a channel section for distributing the gas generated from the inflator to the plurality of chambers; a valve unit provided in the channel section, the valve unit reducing the distributed amount of the gas flowing from the channel section to a particular chamber among the plurality of chambers; and an actuator unit that allows the valve unit to operate to reduce the distributed amount of the gas flowing from the channel section to the particular chamber according to the deployment behavior of any chamber among the plurality of chambers, are included.
US10131307B2	Activation control device for occupant protection device An activation control device for at least one occupant protection device is applied to a vehicle including occupant protection devices. The activation control device includes a front left sensor, a front right sensor and an activation control unit. The front left sensor is configured to detect an acceleration in a vehicle widthwise direction, and the front right sensor is configured to detect an acceleration in the vehicle widthwise direction. The activation control unit is configured to calculate a movement amount of the front left sensor in the vehicle widthwise direction based on GLy, calculate a movement amount of the front right sensor in the vehicle widthwise direction based on GRy, and determine to which region out of regions each defined in advance for each collision form a point defined by those movement amounts belongs, thereby specifying a collision form.
US10131306B2	Travel control method and travel control apparatus A travel control method comprises detecting a travel state of the subject vehicle including a position and a speed of the subject vehicle, acquiring obstacle information including a position and a speed of the obstacle, estimating the second range after a predetermined time on the basis of the travel state of the subject vehicle and the obstacle information, and announcing announcement information that the second range will become small to a driver of the subject vehicle when the second range is estimated to become small after the predetermined time.
US10131305B2	Bumper assemblies and vehicles with integrated air deflectors A bumper assembly includes a bumper cover including one or more air deflectors extending inward from the bumper cover, a bumper reinforcement beam positioned rearward of the bumper cover, and a low speed bumper energy absorber that extends along a front surface of the bumper reinforcement beam between the bumper cover and the bumper reinforcement beam. The one or more air deflectors extend from the bumper cover toward the low speed bumper energy absorber at an oblique angle relative to a front face of the low speed bumper energy absorber to substantially isolate a portion of the bumper assembly from air leakage through the bumper assembly.
US10131303B2	Bumper assemblies and vehicles with integrated air deflectors A bumper assembly includes a bumper cover, a bumper reinforcement beam spaced apart from the bumper cover, and a low speed bumper energy absorber that extends along a front surface of the bumper reinforcement beam between the bumper cover and the bumper reinforcement beam. The low speed bumper energy absorber includes a body portion extending along the front surface of the bumper reinforcement beam, wherein at least a portion of the body portion is space apart from the bumper cover, and one or more air deflectors extending between the body portion and the bumper cover, wherein the one or more air deflectors substantially isolate a portion of the bumper assembly from air leakage through the bumper assembly.
US10131301B2	Passive energy absorber structure adaptable to manage impact energy for different deformation targets and loads An energy absorber is disclosed that includes a container that receives a plurality of tubular segments and at least one spacer. The container includes one side that is adapted to receive an impact from a first direction. The tubular segments are assembled into the container in a parallel array with a cylindrical axis-C of the segments oriented perpendicular to the first direction. The spacer is placed in the container with the tubular segments being arranged to be displaced within the container so that they compress the spacer when the impact force is received on the one side. The method of making the energy absorber comprises assembling the plurality of tubular segments having in a container and assembling at least one spacer inside the container to hold the tubular segments in place.
US10131299B2	Method for controlling the voltage of an apparatus fitted in a motor vehicle Disclosed is a method for controlling the voltage of an electrical apparatus of a motor vehicle. The method includes the steps of measuring (E2) the voltage at the terminals of the apparatus and measuring (E3) the strength of the output current of the apparatus, calculating (E4) the values of resistance, inductance and capacitance of the equivalent circuit on the basis of the measured current strength and the measured voltage, comparing (E7, E8, E9) the calculated values of resistance, inductance and capacitance with the values of resistance, inductance and capacitance, respectively, stored in a storage area of the electronic control unit, and initiating (E12) an action if the difference between at least one of the calculated values and the corresponding stored value is above a predetermined threshold.
US10131295B2	Systems and methods for securing grommet to wiring Systems and methods are provided for securing wiring to a grommet with embedded lubricant by employing a series of pressure rings both on the interior and exterior of the grommet opening. In exemplary implementation, a tie strap is tightened around the wiring and then forced into the grommet opening before a second tie strap is tightened around both the wiring and grommet opening.
US10131293B2	Automobile power supply device An automobile power supply device includes plate-shaped metal wirings and is configured to supply electric power from a battery that is installed in an engine room of a vehicle body to a vehicle interior. The metal wiring may extend in a central portion of a floor surface in the vehicle interior, and the automobile power supply device may include wire harnesses that respectively connect multiple electric devices that are installed in the vehicle body to the metal wiring in the vehicle interior. The metal wiring may be formed by coupling a plurality of wiring materials.
US10131291B2	Assembly-type vehicle component An assembly-type vehicle component 1A, 1B used by assembling one of functional members 3A, 3B having predetermined functions to a mounting member 2 to be mounted to a vehicle body side is configured to allow two types of functional members 3B, 3A to be assembled to the fitting portion 20 of the mounting member 2 so as to be in a detachment-prevented state, and the mounting member 2 has a rattling preventing protrusion 25U for pressing the assembled functional member 3A, and a rattling preventing protrusion 25D for pressing the assembled functional member 3B. Each functional member 3A, 3B has a reception portion 36A, 36B (i.e., gap 37A, 37B) for receiving the rattling preventing protrusion 25D, 25U that is irrelevant to the functional member, so as not to cause pressing.
US10131290B2	Removable and serviceable twist lock assembly clip for blind installation A vehicular assembly and a method of connecting a panel to a vehicular structure in order to form an assembly. The assembly includes a clip that is used to join first and second components each of which defines an aperture therein. The first and second components are sized and shaped such that upon being joined to one another, their respective apertures are substantially aligned with one another and held together by the clip. The clip includes a first connector portion and a second connector portion. The clip can be turned in a twisting or screwing motion about an axis of rotation such that upon insertion of the clip into the aperture of the first component and subsequent rotation, the first connector portion forms a locking engagement with an edge structure that is defined by the aperture of the first component. In addition, upon additional insertion of the clip into the aperture of the second component, the second connector portion of the clip forms a resiliently-biased engagement with an edge structure that is defined by the aperture of the second component. This helps promote the blind installation of automotive components in a more ergonomic manner.
US10131288B2	Strap-type vehicle-to-crossbar coupler assembly A rack for carrying cargo on top of a vehicle that may include a crossbar and a pair of coupler assemblies for connecting opposing ends of the crossbar to raised rails on top of the vehicle. Each coupler assembly may include a body, a securing assembly to secure the body to the raised roof rail, and a crossbar clamp, where the securing assembly and the crossbar clamp are independently adjustable.
US10131283B2	Glove box bin bumper stops A storage compartment for a vehicle glove box includes at least one bumper stop defined by a resilient tab disposed on a storage compartment sidewall, the resilient tab including a cam face, a stop face, and a finger tab accessible from an interior of the storage compartment. The cam face may define an arcuate configuration. The stop face is carried by the finger tab whereby a deflecting force applied to the finger tab deflects the stop face from a retaining position to a releasing position. The storage compartment sidewall defines an aperture disposed to provide access to the finger tab from an interior of the storage compartment. Vehicle glove boxes including the described storage compartment are provided.
US10131281B2	Work vehicle It is an object to provide a work vehicle being capable of arranging side view mirrors at arbitrary positions while reducing the vibration of the side view mirrors. Regarding a tractor, which is a work vehicle in which a mirror portion of a side view mirror is provided on the other end of a support arm whose one end is fixed on a cabin for covering a drive operating unit, the support arm is bent in a midway portion, and a beam is integrally formed with the support arm in such a manner as to sandwich a bending portion, and a cross-sectional area of a cross section vertical to the axial direction of the support arm is configured to be reduced as the support arm advances from the one end to the other end thereof.
US10131280B2	Vehicular video mirror system A video mirror system for a vehicle includes an interior rearview mirror assembly including a mirror case and a reflective element, and a video display device disposed in the mirror case and operable to display video images that are viewable by the driver of the vehicle. The reflective element includes a transflective mirror reflector and the video display device is fixedly disposed to the rear of the reflective element. The interior rearview mirror assembly includes an on-screen display controller operable to receive a video signal from a camera disposed at the vehicle. The on-screen display controller is operable to overlay a graphic overlay onto a video signal received from the camera such that a video feed generated by the on-screen display controller includes the graphic overlay. The video display device comprises a metallic enclosure that is electrically grounded when the interior rearview mirror assembly is mounted at the vehicle.
US10131277B2	Surroundings monitoring apparatus A surroundings monitoring apparatus includes an acquisition portion acquiring captured image data from an imaging portion that captures an image of an area including a road surface in a moving direction of a vehicle and in a vicinity of the vehicle, and an output control portion outputting the captured image data acquired by the acquisition portion to a display device by switching a screen displayed at the display device to the captured image data based on one of a change of a pitch angle of the vehicle and a change of a gradient of the road surface on which the vehicle is driven.
US10131276B2	Vehicle sightline guidance apparatus A vehicle sightline guidance apparatus includes a display member displaying an image on either one one a see-through windshield and screen that allow a vehicle occupant to visually recognize outside of a vehicle; a scenery-information acquiring unit acquiring scenery information visually recognized by the occupant from inside the vehicle; and a perspective-position specifying unit specifying a perspective position, which is a position on the windshield or screen that a sightline passes when the occupant visually recognizes a predicted path of the vehicle or a position where left and right edges of the predicted path are projected, based on the scenery information. Based on the perspective position, the display member displays two reference marks on the windshield or screen such that the marks are separated from each other by a distance equivalent to a vehicle width or larger and appear to be aligned with the left and right edges.
US10131273B2	Lighting module for a motor vehicle A lighting module for a motor vehicle includes a carrier, such as a single printed circuit board, and a plurality of light sources configured to perform various functions selected from a group including door lock status, turn signal indication, blind spot warning indication and door latch handle illumination.
US10131261B2	Seat device for vehicle A seat device for a vehicle includes a dynamic damper attached to a frame of a seat installed in the vehicle. The dynamic damper includes a damper case that is formed from separable first and second case halves, a weight that is housed in a damper chamber, and an elastic member that is disposed between the weight and the damper chamber so as to allow vibration of the weight. The damper case is provided with a plurality of mounting parts that are mounted on the frame, and the mounting parts comprise first and second mounting parts which are engaged with the frame at two left and right places as seen in a front view of the seat, and a third mounting part other than the first and second mounting parts which is provided between the first and second mounting parts.
US10131251B2	Seat adjuster assembly A handle adjuster assembly for a seat track locking mechanism. The handle adjuster assembly includes a seat member and a lever pivotally attached to the seat member. The lever has a first end and a second end adapted to engage with the seat track locking mechanism. A handle is pivotally attached to the first end of the lever at a pivot such that the handle is free to rotate in a first rotational direction relative to the lever about the pivot, and wherein the handle is prevented from rotating in a second rotational direction opposite the first rotational direction about the pivot.
US10131245B2	Electrified vehicle DC power conversion with distributed control An electrified vehicle has a battery pack comprising series-connected battery units providing a main voltage. To supply a lower voltage bus equally from all battery units, a plurality of DC/DC converters are powered by respective units and have their outputs in parallel. A central module has an outer loop controller generating a target current to regulate the bus voltage to a predetermined voltage and has an allocator distributing the target current into a plurality of allocated current commands according to respective states of charge of the battery units. A plurality of local controllers each adjusts a current of a respective DC/DC converter. Each local controller receives a respective allocated current command as a respective feedforward control variable. Each local controller uses an error between the bus voltage and the predetermined voltage to be integrated as a respective feedback control variable only when the error is above a threshold.
US10131244B2	Method for monitoring a battery The invention relates to a method for monitoring a battery (16) in a vehicle (10). The battery (16) comprises multiple battery cells (19) or multiple groups (20) of battery cells (19). The method has the following steps: a) detecting a time curve of an operating parameter of at least one individual battery cell (19) during a driving cycle, b) ascertaining charging processes and discharging processes in the detected time curve of the operating parameter, c) ascertaining a use parameter set which comprises functions that characterize the individual charging processes and discharging processes and the functional parameters thereof, the ascertained charging processes and discharging processes being reconstructed using said characterizing functions and functional parameters, and d) storing the ascertained use parameter set in a non-volatile storage unit (32). The invention additionally relates to a computer program, to a battery system (12) which is designed to carry out the method, and to a vehicle (10) with such a battery system (12).
US10131229B2	Electronic meter cluster for a vehicle An electronic meter cluster system for a vehicle. The system includes a display screen and a meter control module configured to control the display screen. For example, the meter control module is configured to control the display screen to display a meter for conveying information to a driver of the vehicle, the meter including numerals and a pointer needle. The meter control module arranges the needle relative to the numerals to convey information to the driver. Based on a change in the information being conveyed to the driver, the meter control module is configured to modify at least one of sharpness of the numerals, size of the numerals, one or more colors of the display, brightness of the needle, and length of the needle.
US10131228B2	Head-up display apparatus A head-up display apparatus stored in a storage space within an instrument panel of a vehicle for irradiating a display light into a projection area on an upper side of the instrument panel to form a virtual image, is provided. The apparatus includes a display for emitting the display light, a reflecting member supported swingably about a swing axis for reflecting the display light from the display toward the projection area, a drive mechanism arranged in the reflecting member for swinging the reflecting member, and a case storing the display, the reflecting member and the drive mechanism. The drive mechanism includes a drive part and a transmission part for transmitting a drive force of the drive part to the reflecting member. The drive mechanism is arranged at a position shifted from an optical path of the display light nearer the display than the reflecting member.
US10131226B1	Human perception test system and method thereof The present invention provides a human perception test system, which performs a human perception test. The human perception test program and presents on the display module a human perception test interface; the human perception test interface is configured to display a graphic box and an arbitrarily moving graphic; a user operates the control unit to control the graphic box, so that the graphic box and the graphic perform synchronous displacement; when the period of time of the synchronous displacement is equal to a preset time value, two moving speeds of the graphic box within the period of time of the synchronous displacement are acquired; and the micro control unit determines, according to an absolute value of a difference between the two moving speeds, whether the user succeeds in the human perception test.
US10131220B2	Multi-mode hybrid vehicle powertrain apparatus A hybrid powertrain apparatus comprising a first planetary gear device including at least three rotary elements, a first motor, an output axis, and a second motor connected to a first rotary element, a second rotary element, and a third rotary element of the first planetary gear device; a first brake and a second brake provided to vary rotation restricting states of the first rotary element and the third rotary element relative to a fixing member; an engine variably connected to the first rotary element; a clutch configured to variably connect the first rotary element and the engine to vary a mutual rotation restricting state between the first rotary element and the engine; and a speed multiplication gear or a speed reduction gear between the clutch and the engine and connecting the clutch and the engine.
US10131219B2	Suspension link element The invention relates to a link element (1) for a motor vehicle, comprising a connecting rod (2) and a coupling element (3) for coupling the connecting rod (2) to a subassembly of the motor vehicle, wherein the coupling element (3) comprises a housing (5) with a passage (6) through which the connecting rod (2) extends into the housing (5); characterized by a stop plate (7) for supporting forces transferred to the coupling element (3) by the connecting rod (2).
US10131218B2	In-wheel motor for a vehicle and a vehicle comprising the motor The present invention relates to a motor wheel for a vehicle and a vehicle comprising the motor wheel. The motor wheel comprises a wheel, an electric motor, a reduction gear transmitting rotation from the electric motor to the wheel, and a dampening structure connecting the wheel to a vehicle bearing member. The electric motor comprises an electric motor case. The reduction gear comprises a reduction gear case coupled to the electric motor case and rotatably mounted within the wheel hub. The electric motor case is connected to the bearing member of the vehicle and is displaceable relative to the bearing member. The invention improves dynamic properties to the vehicle, reduces vibrations transmitted to the vehicle body, and provides a more comfortable drive.
US10131215B2	Flexible tonneau cover assembly A flexible tonneau cover assembly includes a pair of side rails positioned on side walls of a cargo box of a motor vehicle, two sliding elements slidably received in the side rails, spring blocks inserted within each side rail, and a spring located between the sliding element and the spring block in each side rail. The flexible tonneau cover assembly also includes a front rail including a first end having an opening for receiving a projection of the first sliding element, and a second end having a latch receivable by the latch receptacle of the second sliding element. A tonneau cover is attached to the front rail and extends to cover the cargo box of the vehicle, which is tensioned by the springs.
US10131214B2	Fiberglass roller for tarp deploying device A tarp deploying apparatus for use on a trailer includes a fiberglass tarp roller. The fiberglass tarp roller is constructed from two fiberglass tubes. A splined joint is used to join the two tubes together. Each end of the tarp roller also includes a female socket with grooves to engage splines on a motor shaft that drives the tarp roller or to connect the roller tube to a universal joint. A pin or bolt may also be used at the splined joint to securely hold the tarp roller together without the need for a welding operation.
US10131205B2	Climate control system A climate control system having a coolant subsystem, a heat pump subsystem, and an intermediate heat exchanger. The intermediate heat exchanger may transfer thermal energy from the heat pump subsystem to the coolant to increase the temperature of the coolant when the climate control system is in a heating mode.
US10131203B2	Refrigeration cycle device An ejector draws a refrigerant on a downstream side of an exterior heat exchanger serving as an evaporator, from a refrigerant suction port by a suction effect of an injection refrigerant injected from a nozzle portion for decompressing a part of the refrigerant discharged from a compressor, and mixes the injection refrigerant with the suction refrigerant to pressurize the mixed refrigerant at a diffuser. The refrigerant flowing out of the diffuser is drawn into the compressor. In this way, the density of the refrigerant drawn into the compressor can be increased, thereby suppressing reduction in flow amount of the refrigerant flowing into an interior condenser serving as a radiator. Thus, even if the temperature of the outside air (heat-absorption target fluid) is decreased, the interior condenser is prevented from degrading its heating capacity for the ventilation air (heating target fluid).
US10131201B1	Cooling system for dome of autonomous vehicle A cooling device includes a duct, a passageway, and a plurality of nozzles spaced around the duct. The duct is sized to extend around at least a portion of the dome. The passageway may extend through the duct. The plurality of nozzles may be spaced around the duct and have first openings oriented toward the passageway and second openings oriented toward the surface.
US10131194B2	Amphibian hull An amphibian operable in land and marine modes includes a hull, having a discontinuity, and a retractable wheel or track drive assembly at least partially located in the discontinuity. A wheel or track drive of the at least one retractable wheel or track drive assembly is retracted above a lowest point of the hull when operating in marine mode, and the wheel or track drive is protracted below the lowest point when operating in land mode. The hull is a planing V hull having a forward bow section defining a frontal bow surface/area across a beam of the hull. The discontinuity is provided in the forward bow section, and the wheel or track drive of the retractable wheel or track drive assembly is located ahead of and in front of at least a portion of the frontal bow area when protracted.
US10131192B2	Central tire inflation/deflation system with a timed function CTIS wheel valve A central tire inflation/deflation system (CTIS) with a novel valve that may deflate more quickly and may deflate to a lower pressure than the previously known central tire inflation/deflation system valves. Also, the present valve may not be temperature sensitive, at least because the present valve does not require trapped air behind a diaphragm to operate the valve. The present valve may be placed into existing CTIS's in place of existing valves, without modifying pneumatic lines of the existing CTIS's. Thus, the present valve may be operated by a single fluid flow line, receive pressure from the single fluid flow line, and exhaust to the single fluid flow line. A second communication line, either a pneumatic pilot line or an electrical line, is not necessary, which allows the present valve to be retrofit into an existing CTIS without adding weight or complication from additional components.
US10131190B2	Vehicle wheel having sound-damping structures This vehicle wheel includes: a first vertical wall surface defined by one rising part of a rim that forms a well part and a second vertical wall surface defined by another rising part are provided; an auxiliary air chamber member has a main body part with an auxiliary air chamber on the inside and has edge parts extending from each of both sides of the main body part in the wheel width direction; each of the edge parts of the auxiliary air chamber member fits into a groove formed in each of the first vertical wall surface and second vertical wall surface, and the auxiliary air chamber member is thereby attached atop the outer circumferential surface of the well part.
US10131189B2	Pneumatic tire A pneumatic tire includes: a plurality of land portions; and in at least one land portion of the plurality of land portions, a sipe extending in the tread width direction, of which ends open at the circumferential grooves or the tread ends. The sipe has at least one bent portion extending continuously in the extending direction of the sipe from one of the end regions of the sipe to the other end region in the depth direction of the sipe. The at least one bent portion is located on the outer side in the tire radial direction in the center region than in the end regions.
US10131183B2	Rigid wheel and grouser designs for off-road mobility A wheel includes a circular wheel main body and at least one grouser. The at least one grouser is provided along an outer circumference of the wheel main body and has a contact surface capable of drawing a first tangent line. The first tangent line is inclined opposite to a rotational direction of the wheel main body from the center line of the wheel main body.
US10131182B2	Motorcycle wheel A motorcycle wheel is provided, in particular a motorcycle wheel suitable for use on an enduro motorcycle. The wheel includes a cast or forged rim having integrally spokes which extend toward a central hub connection region. The central hub connection region is configured to receive a hub element in a detachably fastened manner. The hub element forms a hub of the motorcycle wheel which is connectable to a motorcycle.
US10131181B2	Wheel with flexible wide-body spokes A wheel with flexible spokes, including a rim and hub, and spokes between the rim and hub made of fibrous material that causes the spokes to be both lighter in weight and stronger than comparable steel spokes. The spokes are also flexible and resilient such that they can bend while retaining their integrity and strength.
US10131177B2	Barrier coating for a substrate A barrier film, a document including a barrier coating, and a method for producing a document are described. A document includes a substrate, printed data on a surface of the substrate, and a barrier coating. The barrier coating is disposed between a portion of the printed data and a portion of an adhesive. The portion of the adhesive is disposed between a portion of a protective layer and a portion of the substrate.
US10131173B2	Printable film A printable film that contains a base film substrate and an image receiving layer. The film substrate is a polyethylene terephthalate base film substrate that contains inorganic particles and that has an opacity ranging from about 50 to about 95. The image receiving layer comprises, at least, a polymeric network, poly-alkene polymeric compounds and inorganic compounds. Also disclosed herein is the method for obtaining the printable film.
US10131170B2	Protective layer transfer sheet The present invention aims principally to provide a protective layer transfer sheet that can prevent occurrence of fusion between a receiving layer and a transfer layer and occurrence of peeling traces when the transfer layer is peeled from the receiving layer, even in the case that thermal energy applied on transfer of the transfer layer is increased and can obtain a high quality printed article and to provide a protective layer transfer sheet that can impart extremely good scratch resistance to the surface of a printed article. The protective layer transfer sheet includes a substrate, and a transfer layer provided on a surface of the substrate, and the transfer layer includes a binder resin and one or more substances selected from the group consisting of phosphoric acid esters, olefin-maleic acid copolymers, and amino polyether-modified silicone oils.
US10131159B2	Printing device provided with abutting part for suppressing cover from opening due to impact from fall A printing device includes: a printing mechanism; a housing having a casing and a cover; a first frame member; a second frame member; an engaging member; and an abutting part. The first frame member supports the printing mechanism. The second frame member supports the printing medium. The second frame member is juxtaposed with the first frame member in a first direction. The engaging member is supported to the first frame member. The engaging member is movable between a first position in engagement with the cover and a second position out of engagement with the cover. The abutting part is provided at at least one of the first frame member and the second frame member. The abutting part avoids direct contact between the engaging member in the first position and the second frame member when the second frame member is deformed and contacts the first frame member through the abutting part.
US10131153B2	Image-recording apparatus including attachment portion having liquid chamber connectable to liquid cartridge An image-recording apparatus includes a cartridge including a first storage chamber and a first air communication portion, a cartridge-attachment portion including a second storage chamber and a second air communication portion, a switching portion, and a controller. The second storage chamber stores liquid supplied from a supply portion of the cartridge connected to a connecting portion of the cartridge-attachment portion through a liquid outlet port. The switching portion switches the second air communication portion between a first state and a second state. An air flow rate through the second air communication portion per unit of time is lower in the second state than in the first state. The controller determines the liquid level of liquid in the first storage chamber and switches the switching portion to the second state when the liquid level in the first storage chamber is lower than a vertical position of the liquid outlet port.
US10131149B2	Printing assembly A printing assembly has at least one frame, which frame has at least two side walls, between which two side walls a transport path, provided for the transport of printing material, at least partially extends. At least one transport direction is defined by the transport path provided for the transport of printing material. The printing assembly has at least two cross members which are spaced apart from each other in the transport direction and which each extend from one of the side walls to another of the side walls. Each of the at least two cross members has at least one first cross beam and at least one second cross beam spaced apart therefrom, which jointly bound at least one interior of the particular cross member at least partially in and against the transport direction. At least one component of one of a gas transport device and at least one additional device for supplying at least one printing head with one of energy and operating media and printing fluid and data and at least one gas and at least one inner device for one of cleaning and maintaining and covering at least one printing head is arranged in the at least one interior in each case. The printing assembly has at least one supporting body which can be moved, in relation to the frame, in at least one parking direction and which extends at least in a transverse direction between side walls. At least one printing head is arranged on the at least one supporting body and can be moved jointly with the at least one supporting body.
US10131143B2	Printing machines for seamless textiles A printing machine and method for using the same, for printing seamless fabrics provided in tube form, the printing machine comprising a drum on which a tube of the fabric is fitted; and a print head placed in proximity to said drum to print onto the tube fabric as it rotates on the drum. The print head moves axially on the drum to advance the printing.
US10131139B2	Liquid discharging apparatus There is provided a liquid discharging apparatus configured to discharge liquid, including: a liquid discharging head including a driving element; a driving device configured to drive the driving element; a power unit; a switch configured to perform switching of voltage supply; and a controller. When the power unit is switched on, the controller causes a power supply voltage of the power unit to be raised up to a first voltage while checking the power supply voltage; and the controller controls the switch to start the voltage supply from the power unit to the driving device while the power supply voltage is being raised up to the first voltage; and under a condition that the voltage supply is started while the power supply voltage is being raised up to the first voltage, the controller controls the driving device to apply the voltage to the driving element.
US10131137B2	Sheet-fed printing press with a sensor system and methods for calibrating and for aligning the sensor system A sheet-fed printing press includes a printing cylinder and a high-precision sensor system for monitoring a sheet run in the area of the printing cylinder. At least one gage, which is mounted on the printing cylinder, can be detected by the sensor system. It is particularly advantageous if the sensor system is configured to be self-calibrating. A method for calibrating a sensor system and a method for aligning a sensor system are also provided.
US10131136B2	Simultaneous recto-verso printing press There is described a recto-verso printing press (100) adapted to carry out simultaneous recto-verso printing of sheets, the printing press (100) comprising a main printing group (5, 6, 15, 16, 25, 26) with first and second printing cylinders (5, 6) cooperating with one another to form a first printing nip between the first and second printing cylinders (5, 6) where first and second sides of sheets are simultaneously printed, the first printing cylinder (5) acting as a sheet conveying cylinder of the main printing group (5, 6, 15, 16, 25, 26). The printing press (100*) further comprises an additional printing group (7, 8, 17, 18, 27, 28) with third and fourth printing cylinders (7, 8) cooperating with one another to form a second printing nip between the third and fourth printing cylinders (7, 8) where the first and second sides of the sheets are simultaneously printed, the third printing cylinder (7) acting as a sheet conveying cylinder of the additional printing group (7, 8, 17, 18, 27, 28). The main printing group (5, 6, 15, 16, 25, 26) and the additional printing group (7, 8, 7, 18, 27, 28) are coupled to one another by means of an intermediate sheet conveying system comprising one or more sheet-transfer cylinders (10, 10′, 10″)interposed between the first and third printing cylinders (5, 7).
US10131135B2	Imprint apparatus and imprint method An imprint apparatus according to one embodiment includes a contact processing unit and a defect determination unit. The contact processing unit brings a template pattern formed on a front surface of a template into contact with resist placed on a substrate. The defect determination unit determines a defect in an imprint process, on the basis of force which is generated from at least one of the template, the resist, and the substrate, during the imprint process.
US10131134B2	System and method for discharging electrostatic charge in nanoimprint lithography processes Apparatus, systems and methods that use alpha-ionizers to discharge electrostatic charge accumulated on the working surfaces of imprint lithography templates and/or substrates.
US10131130B2	Labels compatible with recycling Adhesive compositions, facestocks and/or packaging labels containing same, where such compositions, facestocks and/or labels designed to facilitate the recyclability of a plastic article formed from any suitable polymer or mixture of polymers (e.g., a polyethylene terephthalate (PET), recycled polyethylene terephthalate (rPET), high density polyethylene (HDPE), polyvinyl chloride (PVC), low density polyethylene (LDPE), polypropylene (PP), polystyrene (PS), polyesters, recycled polyesters, polylacticacid (PLA), biopolymers, cellulose or other types of polymers or plastics) are described. Methods for removing an adhesive composition, facestock and/or packaging label containing same, from a plastic article that is to be recycled and/or subjected to multi-generational recycling are also provided.
US10131125B2	Method of forming three-dimensional composite A method of forming three-dimensional composite comprising steps of: (a) manufacturing at least one shaping member; (b) fitting each of the at least one shaping member on each of at least one mold; (c) adhering at least one connection sheet on said each shaping member so as to form each of at least one semi-finished product; (d) fixing said each semi-finished product in a cavity; and (e) heating said each semi-finished product and vacuuming the cavity. Said shaping member has at least one orifice and covers said each mold, and each connection sheet has a substrate and an adhesive layer, a melting point of the adhesive layer is less than the substrate. Said each semi-finished product in the cavity is heated until the adhesive layer melts, and the cavity is vacuumed so that the adhesive layer penetrates into said each shaping member, thus producing a three-dimensional finished product.
US10131123B2	Multi-layer film composite having a polycarbonate layer The invention relates to a multi-layer film composite having at least one layer made of polycarbonate or copolycarbonate, characterized in that the polycarbonate or copolycarbonate comprises at least one additive of the general formulas (1) to (8), R1 are selected independently of each other from the group made of C10-C25-alkyl, C10-C25-alkoxy, and C10-C25-alkyl-substituted aryl, R2 are selected independently of each other from the group of C10-C25-alkylcarbonyl or hydrogen, and R3 are selected independently of each other from the group of C10-C25-alkyl.
US10131117B2	Fabrication process of coated stamped parts A manufacturing process of a hot stamped coated part comprising the following successive steps, in this order: providing a hot rolled or cold rolled steel sheet comprising a steel substrate and an aluminium-silicon alloy precoating, the precoating containing more than 50% of free aluminium and having a thickness comprised between 15 and 50 micrometers, then cutting the steel sheet to obtain a precoated steel blank, then heating the blank under non protective atmosphere up to a temperature Ti comprised between Te−10° C. and Te, Te being the eutectic or solidus temperature of the precoating, then heating the blank from the temperature Ti up to a temperature Tm comprised between 840 and 950° C. under non protective atmosphere with a heating rate V comprised between 30° C./s and 90° C./s, V being the heating rate between the temperature Ti and the temperature Tm, in order to obtain a coated heated blank, then soaking the coated heated blank at said temperature Tm for a time tm comprised between 20 s and 90 s, then hot stamping the blank in order to obtain a hot stamped coated part, then cooling said stamped part at a cooling rate in order to form a microstructure in the steel substrate comprising at least one constituent chosen among martensite or bainite.
US10131115B1	Hermetically sealed molecular spectroscopy cell with dual wafer bonding A method include forming a plurality of layers of an oxide and a metal on a substrate. For example, the layers may include a metal layer sandwiched between silicon oxide layers. A non-conductive structure such as glass is then bonded to one of the oxide layers. An antenna can then be patterned on the non-conductive structure, and a cavity can be created in the substrate. Another metal layer is deposited on the surface of the cavity, and an iris is patterned in the metal layer to expose the one of the oxide layers. Another metal layer is formed on a second substrate and the two substrates are bonded together to thereby seal the cavity.
US10131111B2	Structural weld pattern A blow molded structure and having ribs formed therein, the ribs defined by a recess in one wall of the blow molded structure that defines two sidewalls on either side of a joint, the joint being a weld between the two opposing walls of the blow molded structure. The ribs are arranged in intersecting paths and a passage is defined in the interior cavity of the blow molded structure at the intersection of two ribs such that fluid flows through the passage during molding.
US10131107B2	Sheet processing device and image forming device provided with the same The present invention is to provide a sheet processing device including: a receiving tray capable of accommodating therein a sheet having, at a part thereof, a protruding portion and a sheet not having the protruding portion in a mixed state; a first binding member that binds the accommodated sheet bundle at a substantially center thereof in a sheet conveying direction; a folding section that folds the sheet bundle bound by the first binding member in two; and a second binding member that binds protruding portions of the sheet bundle folded by the folding section on a fore edge side of the sheet bundle. With this configuration, the fore edge side of the folded and saddle-stitched sheet bundle can be bound by temporary binding. Thus, a sheet processing device capable of ensuring the security of a saddle-stitched sheet bundle can be provided.
US10131105B2	Method of manufacturing a tire tread Method of manufacturing a tire tread having a plurality of raised elements, each having a contact face intended to come into contact with a ground when the tire is rolling and lateral faces connected to this contact face. The method of manufacture comprises: preparing a green form of the tire; laying a cover layer over all or part of an external surface of the green tire; laying the green tire in a mold; with the mold comprising a blade, using this blade to mold a lateral face of a raised element; vulcanizing the green tire to obtain the tire cutting the cover layer using cutting means belonging to the mold; during the molding of the lateral face driving with the blade a cut part of the cover layer into the green tire so that the lateral face of the raised element is partially or fully covered.
US10131102B2	Process and system for manufacturing an ophthalmic lens A process for manufacturing an ophthalmic lens having at least one optical function, includes the following steps: additively manufacturing (100) an intermediate optical element by depositing a plurality of preset volume elements of at least one material having a preset refractive index, the intermediate optical element including a target ophthalmic lens and a thickness allowance consisting of a portion of the plurality of volume elements; and subtractively manufacturing (300), by machining, the target ophthalmic lens from the intermediate optical element, the machining being carried out in a preset sequence, of at least one step, the preset sequence making it possible to subtract the thickness allowance, the additive manufacturing step (100) including a step of determining a manufacturing setpoint for the intermediate optical element in which the thickness allowance is determined depending on the preset sequence defined in the subtractive manufacturing step (300).
US10131100B2	System for minimizing wrinkles in composites A wrinkle mitigation system includes at least one tooling rod disposed against a tool surface at a location on the tool where a composite ply is configured to overlap the tooling rod. The tooling rod may has an elongated shape and is generally oriented along a direction of wrinkle formation in the composite ply. The tooling rod has a rod width that results in the composite ply assuming a corrugated shape when compaction pressure is applied to the composite ply.
US10131099B2	System and method for feeding a fluid to a mold for molding a reinforced composite structure A system and method for feeding a composite fluid to a mold for casting a reinforced composite structure, such as a rotor blade for a wind turbine are provided. The system includes a first feeding unit for feeding a first flow of composite fluid to the mold through a first mold inlet, and a second feeding unit for feeding a second flow of composite fluid to the mold through a second mold inlet. The first flow of composite fluid and the second flow of composite fluid are individually controllable.
US10131095B2	Techniques of additive fabrication using an aspheric lens and related systems and methods According to some aspects, an additive fabrication device for forming solid objects within a build region is provided, the device comprising a laser source, an aspheric lens configured to receive light emitted by the laser source and to produce a light beam having a circular cross section at at least one position inside the build region, and at least one mirror configured to be actuated to reflect the light beam toward a selected position within the build region.
US10131094B2	Air cushion inflation machine An exemplary air cushion inflation machine includes: a first terminal connected to a direct current input; a second terminal; a reference resistor powered by the direct current input; an op-amp; and a transistor. The first terminal of the op-amp is connected to a variable voltage source and the second terminal of the op-amp is connected to the reference resistor. The transistor has a base connected to an output of the op-amp, an emitter connected to the reference resistor, and a collector connected to a first terminal of a sealing band apparatus having first and second terminals. A meltable material placed between the first and second terminals is melted by resistance of current flowing between the first and second terminals. The variable voltage source changes voltage based on a voltage drop measured across the first and second terminals by a voltage measurement device and the constant current.
US10131092B1	Material joint for an inflatable structure and method of constructing the same A material joint connecting an internal spar or baffle to panel walls of inflatable structures. The material joint is formed by a folded center strip and a pair of side strips. The side edges of the center strip are folded to form an initial “T-shaped” cross-section having a middle section, two side sections formed by a first bend, and two overlapping end sections formed by a second bend. The middle section is fused directly to the facing surface of the panel wall and the overlapping end sections are fused together to extend perpendicularly from the middle section. The end strips overlap the center strip with part of the end strips fused to the side sections of the center strip and part fused directly to the panel wall. The spar or baffle is connected to the fused overlapping end sections of the center strip. Under the internal air pressure of the inflated structure, the side sections bow and arc under tension from the connected spar or baffle and the middle section acts as a “bridge” to lift and flatten the exterior surface of the panel wall across its width.
US10131086B2	Micro-structure and nano-structure replication methods and article of manufacture A method for the replication of a textured surface of a master is disclosed, in which the textured surface of the master is comprised of micron-scale cones having nano- or micro-scale surface features. Alternatively, the master may be comprised of micron-scale structures, nano-scale structures, and micron scale structures having nano-scale surface features. Replication can be achieved through a molding or embossing technique. Using these technique, the textured surface of the master is faithfully replicated onto the surface of the replica. A number of representative materials and additional processing steps are also disclosed. The replicated texture exhibits many useful properties, including enhanced hydrophobicity and reduced light reflection properties, making the disclosed method a simple and attractive alternative to existing texturing techniques.
US10131085B2	Clip transporting unit The invention relates to an improved transporting unit for a transporting device, in particular for a transverse, longitudinal, and/or simultaneous stretching installation, wherein transporting units (KT) can be moved along a guiding and/or supporting rail by means of a clip unit (KL) and a drive unit (AT) connected to the clip unit, is characterized by the following features: the clip transporting unit (KT) or the clip unit (KL) and/or the drive unit (AT) has, for example, a volume or weight fraction of at least 60% that consists of a forged part (ST) and/or is composed of a forging blank (SR).
US10131082B2	Method for making dual chamber bottle A multiple-chamber container that is extrusion blow molded with a single neck finish and a method to trim the single neck finish is provided. The physical appearance of the multiple-chamber container before the trimming process differs from the multiple-chamber container after the trimming process. The multiple-chamber container includes multiple openings that are configured to engage with a single cap after the trimming process to create a seal. The multiple-chamber container may contain different materials, such as liquids, gel-like substances, granular materials, food, etc. that are not permitted to flow from one chamber to the other chamber when the cap is engaged with the chamber openings.
US10131077B2	Device for molding semiconductor package A device for molding a semiconductor package including an upper mold configured to retain a substrate thereon, the substrate having semiconductor chips thereon, a lower mold defining a cavity and including a plurality of moving blocks, a bottom surface of the cavity defined by the moving blocks, the cavity configured to contain a molding resin, the moving blocks movably arranged under the cavity, a driving unit configured to movably drive the moving blocks, and a controller configured to control an raising order of the moving blocks by controlling the driving unit may be provided.
US10131075B2	Polyurethane cold cast protective skins formed around and integrated onto existing hand-held computing devices A system and method for bonding a protective cover to a mobile device is disclosed. A cold cast protective cover is permanently bonded to the device and provides protection against damage from dropping, impact, exposure to electric or static discharge, and exposure to liquid, gas, and dusts. The cold cast protective cover takes the shape around all or some desired portion of the outer surface of the mobile device while still providing access to the device's user interface, including display, power and volume buttons, power charging port, memory port, speaker port, camera lens, and the like. The cold cast protective cover can, with additives, increase the safety of the device for Intrinsic Safety or Hazardous environments.
US10131073B2	Monobloc blade preform and module for a turbo machine intermediate casing A fiber preform for a vane module of an intermediate casing of a turbine engine, the preform being obtained by three-dimensional weaving. The preform includes first longitudinal segment presenting opposite first and second ends and suitable for forming a first vane; a second longitudinal segment presenting first and second opposite ends and suitable for forming a second vane; and a first transverse segment connecting together the first and second longitudinal segments by their first ends, and suitable for forming a first transverse vane portion such as a flange or a platform.
US10131071B2	Device system including a radio link A device system, including a remote control (13) having a device housing (31) and a first radio unit (38), a tool device with a second radio unit and a radio link which connects the first radio unit (38) of the remote control (13) to the second radio unit of the tool device. The first radio unit is (38) is arranged on a front side (57) of the device housing (31), wherein the front side (57) is lying opposite a rear side (56) of the device housing (31) facing the operator in a working position of the remote control (13).
US10131070B2	Sheet punching device and image forming apparatus A sheet punching device including: a die which has a die hole and is configured to be driven to rotate; a punch configured to move in and out of the die hole to punch a hole in a sheet; and a punch operating unit configured to reciprocate the punch with respect to the die hole in a state in which the punch is opposed to the die hole of the die, to move the punch in and out of the die hole.
US10131058B2	Robot arm mechanism A purpose is to prevent a first connection piece string from colliding against a second connection piece string in a robot arm mechanism including a linear extension and retraction joint. In the robot arm mechanism having the linear extension and retraction joint, the linear extension and retraction joint includes an arm section, and an ejection section for supporting the arm section, the arm section includes a first connection piece string 21 made by a plurality of first connection pieces, and a second connection piece string made by a plurality of second connection pieces, the second connection piece string is sent out forward from the ejection section together with the first connection piece string in a state where the second connection piece string is joined to the first connection piece string, and a flexible guide rail for separating the first connection piece string from the second connection piece string and guiding the second connection piece string to the ejection section is interposed between the first connection piece string and the second connection piece string behind the ejection section.
US10131052B1	Persistent predictor apparatus and methods for task switching An apparatus and methods for training and/or operating a robotic device to perform a target task autonomously. The target task execution may be configured based on analysis of sensory context by the robot. Target action may comprise execution of two or more mutually exclusive actions for a given context. The robotic device may be operable in accordance with a persistent switching process. For a given sensor input, the switching process may be trained to select one of two or more alternative actions based on a prior action being executed. Switching process operation may comprise assigning priorities to the available tasks based on the sensory context; the task priorities may be modified during training based on input from a trainer. The predicted task priorities may be filtered by a “persistent winner-take-all process configured to switch from a current task to another task based on the priority breaching a switching threshold.
US10131051B1	Anticipation-based robotic object grasping A grasp management system is described. The grasp management system may be configured to determine a grasp strategy for a robotic manipulator. Information about an initial state of an object may be accessed. Information about a final state of the object may also be accessed. The final state may enable a subsequent interaction with the object. An anticipated pose space may be determined that enables the subsequent interaction with the object. An initial pose for the robotic manipulator may be determined based at least in part on the anticipated pose space. The initial pose may be used by the robotic manipulator to grasp the object.
US10131048B2	Connection device and drive assembly for a cutting tool The present invention provides a connection device or tool (10, 110, 210, 310, 410, 510, 610, 1110, 2110, 3110, 4110) to connect a first tool (80, 90) to a second tool (90,80), the connection device or tool (10, 110, 210, 310, 410, 510, 610, 1110, 2110, 3110, 4110) comprising at least one shell member 30 which clamps a first end to said first tool (80, 90) and a second end of said at least one shell member 30 to engage with said second tool (90,80), whereby relative rotation between said first tool and second tool is prevented, and axial separation of said first tool (80, 90) and second tool (90,80) is prevented or is assisted in being prevented. This results in a safer combination of the first tool (80, 90) and second tool (90,80), and allows for a one handed operation of the combination.
US10131046B2	Fastener and installation device A fastener and a fastener installation device which enables cables to be installed in hard to reach places safely and quickly. The fastener including a body forming a loop; a first connector formed at a first end of the body; and a second connector formed at a second end of the body; wherein the first connector is complementary with the second connector. The first connector of the first fastener connects with a second connector of a second fastener and the second connector of the first fastener connects with a first connector of a third fastener to form a chain of fasteners. The installation device including a hollow body and a cap rotatably mounted to an end of the hollow body which includes an aperture allowing a top fastener to pass through the aperture when the cap is in a first position.
US10131040B2	Cannulated ultra high torque device A torque-limiting device may include a shaft extending axially through upper and lower shanks and a spring to connect to a nut. The upper and lower shanks may be under a force from the spring and further configured to selectively engage within a predetermined torque limit and disengage at above the predetermined torque limit. Accordingly, the shaft may receive torque up to the predetermined limit as provided by a user operating a handle of the torque-limiting device. The torque-limiting device may be disposable, reusable, economical, and have high torque capabilities. The shaft may include a lumen extending there through, and through which a variety of devices and materials may be delivered to a workpiece.
US10131039B2	Surgical devices and methods for driving an implant and applying counter torque Devices, systems, and methods are provided for driving an implant and applying counter torque. For example, a driver can include a handle, a driver shaft, and a counter torque shaft, the counter torque shaft being laterally offset from the driver shaft. A distal end of each shaft can mate with a specific type of implant and/or anatomy. The shafts can be removed and replaced from the device, allowing a user to select shafts having particular lengths and/or mating tips. In use, distal ends of the shafts can be fixed or constrained relative to one another and to an implant such that the counter torque shaft cannot orbit around the driver shaft. Rotating the handle can rotate the driver shaft, driving the implant. This can cause the counter torque shaft to try to orbit around the driver shaft, but the fixed/constrained ends restrict this motion, applying the counter torque.
US10131036B2	Method and device for manufacturing elastic abrasive method for blasting the elastic abrasive including method for recycling the elastic abrasive and device for blasting the elastic abrasive including device for recycling the elastic abrasive To obtain a circulation-type blasting device which enables stable processing for a long period of time even in a case that an elastic abrasive of which abrasive grains are attached to a surface of an elastic core are used.A circulation-type blasting device is provided with a device for recycling an elastic abrasive for recycling all or a part of elastic abrasive used in a cyclic way, and the device for recycling the elastic abrasive is provided with a mixing unit for mixing recovered abrasives recovered from an abrasive recovery unit and abrasive grains introduced from an abrasive grain supplying unit in a gas flow by introducing the abrasive grains and the recovered abrasive in the gas flow to generate a solid-gas biphase flow, and a combining unit composed of at least one bent space to which the solid-gas biphase flow is introduced.
US10131035B1	Surface finishing Grooves are formed on an exterior surface of a component. The grooves are formed proximate to one another such that the grooves diffract light. The exterior surface is processed to reduce the sharpness of peaks between the grooves, reduce differences between the peaks and valleys of the grooves, and/or roughen the grooves. The processing reduces diffraction caused by the grooves such that light reflected from the grooves is not substantially color-shifted (e.g., is or is near the color of the reflecting surface). In various implementations, the processing may include dry blasting, etching, abrasive blasting, burnishing, grinding, ablation, an/or any other process capable of reducing the sharpness, reducing the differences, and/or roughening the surface. In implementations where dry blasting is used, the dry blasting may use ceramic beads as a blast material.
US10131028B1	Adjustable sharpening apparatus and method for cutting implements An apparatus for sharpening a cutting implement includes a base assembly and first and second clamping members pivotably supported by the base assembly. The clamping members each have an inside surface, a proximal end portion, and a distal end portion, where the second inside surface faces and is spaced apart from the first inside surface. The clamping members are adapted to pivot to clamp a cutting implement between the inside surfaces. A clamping assembly attached to the base assembly includes a cam member movably supported by the base assembly, a follower assembly disposed in operational engagement with the cam member and with the proximal end portions of the first and second clamping members. A handle is operatively connected to the cam member, where operating the handle moves the cam member, thereby moving the follower assembly and pivoting the first and second clamping members.
US10131027B2	Projected scale for depth measurement A device for determining a penetration depth in a drilled hole which is drilled into a workpiece (W) from a workpiece surface (WO) with a drill of a drilling machine. The device contains at least one light source for projecting a light field is provided onto a workpiece (W) to be processed by the drilling machine. The light source is positioned with respect to the drilling machine in such a way that a center axis (L) of the light source runs at an angle (a) with respect to a central axis (L) of the drilling machine, and at least a first blocking element for partially covering the light source is provided, said blocking element forming a reference on the light field.
US10131025B2	Workpiece positioning device for positioning workpiece A workpiece positioning device has a more simple structure and a low cost. The workpiece positioning device includes a movable base on which a workpiece is placed, drive mechanisms for moving the movable base, a vision sensor for repeatedly detecting the current position of the workpiece placed on the movable base, a difference calculating part for calculating the difference between the current position and the target position each time the current position is detected by the vision sensor, a difference determining part for determining whether the difference is within an allowable range, and a drive controller for controlling the drive mechanisms so as to stop the movement of the movable base when it is determined that the difference is within the allowable range.
US10131024B2	Rotatable interchangeable work surface mount An assembly which provides a rotating work surface extension. The assembly may be attached or fixed to an existing work space platform. An assembly comprising interchangeable rotating work surface extensions is disclosed, along with a system comprising such an assembly and a method of positioning a workpiece utilizing such an assembly.
US10131020B2	Part orienter with removable rotating fixture A machine for manufacturing parts that includes a base having therein one or more motors, an electrical power input port and a connector for connection to a general purpose programmable controller, and including a removable part holding and aligning (or presenting) fixture which can hold and rotate one or more parts to a specific location. The machine can include a tool for performing a process on a part. The machine can include a programmed general purpose controller that can control the operation of the machine during a manufacturing process.
US10131019B2	Laser processing method and laser processing machine A laser processing machine for carrying out hole-forming on a plate-shaped workpiece is provided. A first program storage that stores a plurality of hole-forming programs and a second program storage that stores a plurality of cutout piece drop programs are also provided. A program selector that selects, from the second program storage, a cutout piece drop program associated with a hole-forming program selected from the first program storage to form the hole on the workpiece. A working head controller that controls a laser processing head according to the hole-forming program and the cutout piece drop program that are selected is also provided. A motion path of the processing head after forming the hole on the workpiece and a jetting condition of assist gas to an inside of the outline from the processing head on the motion path are programmed in each of the plurality of cutout piece drop programs.
US10131018B2	Grain-oriented magnetic steel sheet and method of producing the same A grain-oriented magnetic steel sheet includes grooves each of which extends in a direction intersecting a transportation direction, the grooves being formed at predetermined pitches PL in the transportation direction by laser beam irradiation, in which a relationship between a standard deviation value D and the pitch PL satisfies the following expression (1), the standard deviation value D being a standard deviation of distances between a linear approximation line, which is obtained from a center line of each of the grooves in a groove width direction by a least-squares method, and respective positions on the center line, and an average angle formed between tangent lines of the respective positions on the center line and a direction perpendicular to the transportation direction is more than 0° to 30°. [Expression 1] 0.02≤(D/PL) (1)
US10131017B2	Laser nanomachining device and method According to one aspect, the invention relates to a device (1, 2, 3) for laser nanomachining a sample made of a material having a given transparency band, the device comprising: a focusing module (203, 703) allowing a nondiffracting beam (210, 710) to be generated, along a focusing line generally oriented along the optical axis of the focusing module, from a given incident beam; first means (202, 702) for emitting a first light pulse (I1) of spectral band comprised in the transparency band of said material, able to generate in said material, after focusing by said focusing module, a plasma of free charges along said focusing line via multi-photon absorption, thus forming a “plasma channel”; and second means (202, 702) for emitting at least one second electromagnetic wave (I2) of spectral band comprised in the transparency band of said material, which wave(s) is/are intended to be spatially superposed on said plasma channel in order to heat said material via absorption by the free charges of the plasma.
US10131014B2	Machine for flash-butt welding of rails Application of the machine for flash-butt welding of rails with one rod, which connects two tong-type clamping devices is widening greatly the functional capabilities at its service, both in welding of separate rails and also in repair of rail tracks under the field conditions and in hard-to-reach places such as railway switches and frogs, the underground tracks, rails, which are laid side by side at a close distance, etc., not changing the optimum process and quality of the welded joints.
US10131007B2	Cutting tool and method for its manufacture A cutting tool (2) is specified with a cutting region (4) that comprises a substrate (12) onto which a coating (10) is applied, which coating (10) is subsequently processed, whereby a sharp cutting edge (8) is formed. Furthermore, a corresponding method for the manufacture of the cutting tool (2) is specified. By means of the sharpening of the cutting edge (8) after the coating rather than before, a particularly sharp cutting edge (8) is formed, whereby the precision of the cutting tool (2) as well as its service life is improved.
US10131006B2	Pneumatic device for a pneumatic saw A pneumatic device includes a cylinder, a buffer member and a piston unit. The cylinder includes a cylinder wall defining an air chamber. The buffer member has a tubular wall that defines a communicating hole. The tubular wall has a length greater than the wall thickness thereof. The piston unit includes a sealing member, and a rod member movably extending through the communicating hole. The rod member has a driven section received within the air chamber and mounted with the sealing member. The piston unit is movable between a restoring position where the driven section is spaced apart from the buffer member, and an impact position where at least one of the driven section and the sealing member is in contact with the buffer member.
US10131002B2	Cutting insert having varying rake angle and variable-width land, and cutting tool A polygonal cutting has opposing first and second end surfaces connected by a side surface, and a plurality of cutting edges formed between the end surfaces and the side surface. Each cutting edge is formed at corner and includes a corner cutting edge and a major cutting edge connected to the corner cutting edge. A rake surface formed along the cutting edge on first the end surface is inclined toward the second end surface. In a side view of the cutting insert, the major cutting edge includes an inclined part which is inclined so as to approach the second end surface from the corner cutting edge. A portion of the rake surface along the inclined part is formed such that an angle of inclination toward the second end surface increases toward the corner in a direction along the intersecting edge between the first end surface and the side surface.
US10130997B2	Main shaft device and machine tool provided with same This device is provided with: a main shaft (20) onto which a tool (100) is detachably mounted; a rod (30) slidably supported by the main shaft (20) and configured to attach or detach the tool (100) to or from the main shaft (20) through a sliding action; a fluid channel (32) formed in the rod (30); fluid feed device (51, 70) configured to feed a fluid into the fluid channel (32); a plurality of fluid channels for seating detection (24) for detecting when the main shaft (20) and the tool (100) are in a seated state, the fluid channels for seating detection (24) being formed in the main shaft (20) so as to communicate with the fluid channel (32) when the rod (30) is positioned at a first position; and a plurality of fluid channels for cleaning (25) for cleaning seating portions of the main shaft (20) and the tool (100), the fluid channel for cleaning (25) being formed in the main shaft (20) so as to communicate with the fluid channel (32) when the rod (30) is positioned at a second position different from the first position.
US10130995B2	Method for manufacturing metal powder A method for manufacturing metal powder comprising: providing a basic metal salt solution; contacting the basic metal salt solution with a reducing agent to precipitate metal powder therefrom; and recovering precipitated metal powder from the solvent.
US10130993B2	Additive manufacturing of three-dimensional articles The present invention relates to a method for forming a three-dimensional article through successively depositing individual layers of powder material that are fused together so as to form the article, the method comprising the step of heating a first portion of a support surface while depositing a layer of powder material on a second portion of the support surface.
US10130992B2	Processes for making silver nanostructures The present invention is directed to a process for making silver nanostructures, comprising reacting at least one polyol and at least one silver compound that is capable of producing silver metal when reduced, in the presence of a source of chloride or bromide ions, at least one copolymer, and at least one acid scavenger. The present invention is also directed to silver nanostructures made by the processes described herein.
US10130991B2	Casting system and a method of casting using the same A casting system includes a casting surface; a rim area disposed on the casting surface or associated therewith; a heat resistant impermeable diaphragm having an edge area. The diaphragm covers a portion of the casting mold when it is positioned on the surface so as to form a space defined by at least a base constituted by the surface, and at least a casting face constituted, at least partially, by the diaphragm; a sealing arrangement for sealingly engaging the rim and edge areas, thereby sealing the space; an outlet for withdrawing gas from the space; a heat resistance coefficient of the diaphragm is such that it can melt when coming in contact with the molten material. The diaphragm covers an area larger than that through which molten material is case so that, when the space is sealed, vacuum application causes the diaphragm to adhere to a portion of the mold.
US10130989B2	Evaporate pattern casting method An opening is provided in a foam pattern, and a coating agent is applied to the opening. The coating agent applied to the opening is taken as a beam having a sectional secondary moment I (mm4), a vertical plate thickness h (mm), and a length L (mm). It is assumed that a volume of a cavity part in the foam pattern is V (mm3), a bulk density of the casting sand filling the cavity part is ρs (kg/mm3), a gravitational acceleration is g (mm/sec2), a density of the melt is ρm (kg/mm3), an angle of the opening with respect to a vertical direction is θ, and a transverse strength of the coating agent at the highest temperature during pouring of the melt is σb (MPa). A sectional shape of the opening, the angle θ of the opening, and the transverse strength σb of the coating agent are selected to satisfy the expression: σbI>V(ρm−ρs)g{(hL/2)sin θ−cos θ}.
US10130981B2	Method and device for descaling a metallic surface and installation for producing semifinished metallic products A method for descaling a metal surface of a semifinished metal product, including the steps of: guiding the semifinished metal product in a transporting direction past nozzle head parts that rotate about rotation axes and are arranged alongside one another transversely to the transporting direction; and directing high-pressure fluid jets produced by nozzle elements arranged on the rotating nozzle head parts at the metal surface. The fluid jets also being blasted as far as the metal surface at a narrow point between two immediately adjacent nozzle head parts. The nozzle head parts rotate synchronously with one another at a preset angular position with respect to a rotation angle of a particular rotation axis of the nozzle head parts. The fluid jets produced by the nozzle elements are always blasted onto the metal surface past one another without coming into contact with one another.
US10130980B2	Cooling facility and method A cooling method for a rolling ingot of aluminum alloy after metallurgical homogenization heat treatment of said ingot and before hot rolling, characterized in that cooling by 30 to 150° C. is performed at a rate of 150 to 500° C./h, with a thermal differential of less than 40° C. throughout the treated portion of the ingot is disclosed. A facility allowing use of said method and said implementation is also disclosed.
US10130978B2	Cleaning method of oil tank and cleaning device of same Crude oil is discharged from an oil tank. A nozzle is inserted into a support opening formed in advance on a roof of the oil tank. A cleaning liquid containing LCO is injected from the nozzle over the sludge accumulated inside the oil tank after the crude oil is discharged from the oil tank. The cleaning liquid in which the sludge is dissolved is discharged from the oil tank and is returned to the oil tank for recycle cleaning. Subsequently, the cleaning liquid in which the sludge is dissolved is discharged from the oil tank.
US10130977B1	Elevated potable water tank and tower rotary cleaning system A system for vacuuming out sediment when installed on the inside of a gravity feed, elevated potable water tank or tower holding water at a pressure head of the kind having a riser serving as a water inlet and outlet. The system having a rotating manifold driven by a rotational drive mechanism installed along the bottom wall of the tank or tower connected to a plurality of downwardly directed nozzles. The rotating manifold is connected to a drain pipe passing down through the or alongside the tank riser and is supported so that the nozzles are positioned above the bottom wall in the vicinity of the sediment. When water is allowed to flow through the drain pipe, the pressure head causes sediment which may otherwise be a health risk and promote electrolytic corrosion to be vacuumed out by the nozzles.
US10130967B2	Portable shower device A portable shower device for portable showering purposes includes a tank that defines an internal space. The tank is configured to store water. A hose is sealably coupled to and extends from the tank. The hose is fluidically coupled to the internal space. A spray head is coupled to an external end of the hose. A pump is sealably coupled to the tank. The pump is configured to pressurize the tank such that water is motivated through the hose to the spray head. A pair of axles is singly and rotationally coupled to a bottom of the tank proximate to a back and a front of the tank. Wheels are coupled singly to each opposing end of each axle. A handle is positioned on the front of the tank for grasping by a user to motivate the tank upon the wheels.
US10130966B2	Masking material, method for producing masking material, and masking method A masking material for use in a heating process includes: a base material comprising a resin as a main resin component and containing a magnetic substance, the resin having a higher melting point than a temperature of the heating process, the magnetic substance having a higher Curie temperature than the temperature of the heating process; and a releasable protective layer formed on one surface of the base material, the releasable protective layer comprising a releasable protective material. The masking material has excellent heat resistance property and can be repeatedly used.
US10130963B2	Siphon-type airbrush A siphon-type airbrush, comprising a front handle, a tail handle, a needle, a sprayer, a nozzle, an air inlet valve and a nozzle base; the front handle corresponds to the tail handle to form an airbrush body; the airbrush body is internally formed with an accommodating cavity; the accommodating cavity is internally provided with the needle; the front handle is internally provided with a siphon channel; the air inlet valve is disposed at the middle part of the airbrush body; the rear end of the nozzle base is in threaded connection with the front handle; the front end of the nozzle base is in threaded connection with the sprayer; the nozzle comprises a nozzle body; the nozzle body is pressed between the sprayer and the nozzle base; the front end of the nozzle body extends to form a nozzle tip.
US10130962B2	Wirelessly controlled trigger start and chemical tank change-over for pressure washers A pressure washer includes a prime mover, a pump driven by the prime mover, and a spray gun fluidly coupled to the pump. The spray gun includes a flow-control valve movable between an open position and a closed position to control a fluid flow from the spray gun, a user interface for controlling the flow-control valve, a sensor configured to detect the state of the user interface, and a first wireless system electrically coupled to the sensor. In a first state of the user interface, the flow-control valve is in the closed position. In a second state of the user interface, the flow-control valve is in the open position. The pressure washer further includes a second wireless system electrically coupled to the prime mover. The second wireless system signals the prime mover to start to drive the pump to provide fluid to the spray gun upon receiving a start signal from the first wireless system indicating that the sensor detects the user interface in the second state.
US10130959B1	Shower unit with easy to change water outflow rate A shower unit, comprises a water inlet assembly and a water outlet assembly mounted on a housing, water outlet channels are arranged on the water outlet assembly, a water inlet and a water outlet are formed in the water inlet assembly, two water inlet channels are arranged in the water inlet assembly, each water inlet channel can communicate with the water inlet and the water outlet independently, and the water outlet channels communicate with the water outlet to spray water; an electromagnetic valve is mounted in one water inlet channel, a circuit board mounted on the housing is electrically connected with a switch, each time the switch is pressed, the circuit board powers on and then powers off the electromagnetic valve after a set delay, which respectively opens and closes the water inlet channel. The water outflow rate of the shower unit can be changed rapidly, and has water-saving effects.
US10130958B2	Showerhead assembly with gas injection distribution devices A method and apparatus that may be utilized for chemical vapor deposition and/or hydride vapor phase epitaxial (HVPE) deposition are provided. The apparatus includes a showerhead assembly with separate inlets and manifolds for delivering separate processing gases into a processing volume of the chamber without mixing the gases prior to entering the processing volume. The showerhead includes a plurality of gas distribution devices disposed within a plurality of gas inlets for injecting one of the processing gases into and distributing it across a manifold for uniform delivery into the processing volume of the chamber. Each of the gas distribution devices preferably has a nozzle configured to evenly distribute the processing gas flowing therethrough while minimizing recirculation of the processing gas within the manifold. As a result, improved deposition uniformity is achieved on a plurality of substrates positioned in the processing volume of the processing chamber.
US10130951B2	Open-ended conical tube for recovering cells from a microfludic chip Provided are devices for recovery of cells from a microfluidic device. In particular, provided are open-ended conical tubes for recovery of cells from a microfluidic device and methods of use. In some embodiments, the open-ended conical tubes comprise: i) a nipple portion (7), wherein the nipple portion (7) comprises a length in the range of 0.2 to 0.3 inches, a diameter in the range of 0.2 to 0.3 inches, wherein the nipple portion (7) comprises a narrow orifice; ii) a conical portion (5) attached to and in fluid communication with the nipple portion, wherein the conical portion (5) has a length in the range of 1.0 to 1.5 inches and the angle of the outer surface of the conical portion (5) of the tube in relation to the outer surface of a cylindrical portion (1) of the tube is between 30° to 45° , wherein an outer circumferential surface of the conical portion (5) is attached to a flange (6) comprising a cylindrical cavity (12), wherein the cylindrical cavity (12) is formed into the surface of the flange (6), and the flange (6) is attached to the outer circumferential surface of the conical portion (5) of the tube such that the opening of the cylindrical cavity (12) extends perpendicularly with respect to the longitudinal axis of the tube, wherein a cap of a PCR tube fits into the cylindrical cavity (12) in the flange (6); iii) the cylindrical portion (1) attached to and in fluid communication with the conical portion (5) and having an axis substantially co-linear with an axis of the conical portion (5), wherein the cylindrical portion (1) comprises a wide orifice and threads (8) on the outer surface abutting the wide orifice to accommodate a cap for the conical tube, wherein the cylindrical portion (1) comprises a length in the range of 2.2 to 2.8 inches, an outer diameter in the range of 1.10 to 1.19 inches along its entire length and an inner diameter configured to accommodate one or more microfluidic chips or slides.
US10130949B2	Microfluidic system The present invention concerns a microfluidic system comprising: a microchannel containing several elements of two non-miscible fluids, the microchannel comprising a droplet (30) containing magnetic particles (M), and a device for generating inside the microchannel magnetic field, said device comprising an activable magnetic element, the activable magnetic element comprising a tip (5,6), the microfluidic system being configured to transport the droplet by flow or by pressure difference.
US10130948B2	Microfluidic device and control equipment for microfluidic device Provided is a microfluidic device to more easily and mechanically operate a valve for controlling a fluid flow, which comprises: a platform having a plurality of chambers; at least one flow channel which connects between the chambers; and a valve which opens or closes the flow channel, wherein the valve includes a blocking member which selectively blocks the flow channel and a pressing member installed in the blocking member to move the blocking member, and the pressing member has a structure which presses and moves the blocking member by the linear reciprocating motion in the same direction as the direction of an external force, and the valve further includes a driving unit which reversibly controls the opening and closing of the flow channel caused by the blocking member by fixing the pressing member to the position of the moved pressing member or returning to the original position.
US10130946B2	System for detecting rare cells This disclosure provides a system for detecting rare cells. The system includes a substrate, extensions extending outwardly from the substrate and arranged about a center axis of the substrate to define a channel enabling the fluid to move radially from the center axis to an outer edge of the substrate, and a functionalized graphene oxide disposed on the extension. This disclosure also provides a method for detecting rare cells using the system of this disclosure. The method includes the steps of introducing a sample of fluid containing the rare cells into the inlet of the system such that the sample of fluid flows radially from the inlet toward the outer edge of the substrate and capturing the rare cells as the rare cells interact with the functionalized graphene oxide disposed on the extensions.
US10130945B2	Cell pathology tubes and associated cell processing methods Cell tubes that can be used both for pathology collection and subsequent cell processing include a tube with a cell bed at a lower portion of the tube. The tube can include a base member that can be detachable from the tube body. The tubes can be used to form cell (cytology) blocks that incorporate the cell bed. The cell bed can be an inert cell bed of paraffin.
US10130943B2	Catalyst composition for fluid catalytic cracking, process for preparing the same and use thereof The present invention provides a catalyst composition for use in a catalytic cracking process, said catalyst composition comprises 3.5 to 15.5% of pentasil zeolite, 9 to 40% of ultra-stable Y (USY) or rare earth exchanged USY (REUSY) zeolite, 3.5 to 15% of large pore active matrix based bottom up gradation component and 0.3 to 3% of a metal trap component, the percentage being based on weight of the catalyst composition. The present invention also provides a process for preparing the said catalyst composition and a catalytic cracking process comprising contacting the said catalyst composition with a feedstock.
US10130937B2	Preparation method for rod-shaped molybdenum oxide and preparation method for molybdenum oxide composite The present specification relates to a preparation method for rod-shaped molybdenum oxide and a preparation method for a molybdenum oxide composite, the preparation method for rod-shaped molybdenum oxide according to the present invention may be carried out under low temperature and pressure conditions, and thus has an advantage in that it is possible to mass produce rod-shaped molybdenum oxide, and the preparation method for a molybdenum oxide composite according to the present invention has an advantage in that the molybdenum oxide composite may be synthesized at a temperature which is equal to or less than the boiling point of ethanol, and the amount of an ethanol solvent used is reduced.
US10130936B2	Alumina-supported vanadium oxide dehydrogenation catalyst Fluidizable catalysts for the gas phase oxygen-free oxidative dehydrogenation of alkanes, such as propane, to corresponding olefins, such as propylene. The catalysts comprise 5-20% by weight per total catalyst weight of one or more vanadium oxides (VOx), such as V2O5. The dehydrogenation catalysts are disposed on an alumina support that is modified with calcium oxide to influence characteristics of lattice oxygen at the catalyst surface. Various methods of preparing and characterizing the catalyst as well as methods for the gas phase oxygen free oxidative dehydrogenation of alkanes, such as propane, to corresponding olefins, such as propylene, with improved alkane conversion and olefin product selectivity are also disclosed.
US10130931B2	Super absorbent polymer and method of preparing the same Disclosed are a granular super absorbent polymer, including particles (A) having an average diameter of 150 to 850 μm, wherein the particles (A) includes particles (a1) having an average diameter of 500 to 850 μm; and particles (a2) having an average diameter of 150 to 250 μm, and the particles (a1 and a2) have a water-solubility index of 0.08 to 2.0 (represented by Equation 1), thereby it is possible to maintain a proper amount of extractables in a resin, and to exhibit excellent flow conductivity and water absorption ability in a case of being actually applied to products, without inducing any skin problem when, as well as a preparation method thereof.
US10130930B2	Sorbent comprising carbon and nitrogen and methods of using the same The present invention relates to sorbents including carbon and nitrogen. In various embodiments, the sorbent can remove mercury from a mercury-containing gas that includes sulfur (VI) such as SO3 more efficiently than other sorbents. The sorbent can include a graphene edge comprising an active site for mercury oxidation and a nitrogen layer structure including cationic nitrogen atoms, neutral nitrogen atoms, or a combination thereof proximate the active site.
US10130919B1	Method for making a polygraphene membrane for water desalination A method for preparing a polygraphene membrane includes adding graphite and sodium nitrate into sulfuric acid to form a first mixture; adding potassium permanganate solution into the first mixture to form a second mixture; adding hydrogen peroxide solution to the second mixture to form a mixture including soluble manganese ions; filtering the mixture including soluble manganese ions to form an aqueous suspension; centrifuging the aqueous suspension; performing ultrasonication of the suspension to obtain graphene oxide sheets; acylating the graphene oxide sheets to prepare an acylated graphene oxide sheet; and polymerizing the acylated graphene oxide sheets to prepare polygraphene.
US10130913B2	Exhaust gas purification system, and NOx purification capacity restoration method There is provided an exhaust gas purification system including: a NOx storage-reduction catalyst that is provided in an exhaust system of an internal combustion engine 10 to reduce and purify NOx in exhaust gas; a deterioration degree estimation module for estimating a degree of deterioration of the NOx storage-reduction catalyst; a NOx storage amount estimation module for estimating a NOx storage amount of the NOx storage-reduction catalyst; a regeneration control unit for starting a regeneration process in which a NOx storage capacity of the NOx storage-reduction catalyst is restored when a NOx storage amount that is estimated by the NOx storage amount estimation module reaches a predetermined storage amount threshold; and a storage amount threshold correction module for correcting the storage amount threshold based on the degree of deterioration that is estimated by the deterioration degree estimation module.
US10130909B2	Process for drying a gas stream comprising 2,3,3,3 tetrafluoropropene A method of drying a fluid comprising a fluoropropene, which method comprises the step of contacting the fluid with a desiccant comprising molecular sieve having openings which have a size across their largest dimension of from about 3 Å to about 5 Å. A heat transfer device comprising a heat transfer fluid comprising a fluoropropene, and a desiccant comprising a molecular sieve having openings which have a size across their largest dimension of from about 3 Å to about 5 Å. Preferably, the fluoropropene is R134yf or R-1225ye.
US10130906B2	Purification of a gas stream At least one gaseous impurity, for example silane, is removed by absorption from a feed gas stream, for example a gas stream comprising nitrogen and hydrogen, the gaseous impurity being less volatile than the feed gas stream. The absorption is effected by a sub-cooled absorbent at a first cryogenic temperature and a first pressure. The absorbent is typically propane. The absorption may be conducted in a liquid-vapor contact column (130). Absorbent containing impurity may be regenerated in a regeneration vessel 150 and returned to the column (130).
US10130903B2	Filter with dual pleat pack A fluid filter apparatus comprising an upper housing shell; a lower housing shell; a pleat pack element comprising a peripheral frame and a folded pleated media. The frame is at least partially molded over the media to secure the media in the frame, and the media comprises two or more types of media of different densities from each other.
US10130901B2	Systems for emptying pit latrines and septic tanks An example system includes an auger assembly that is attachable to a vacuum system, in which the auger assembly includes a hose, an auger, and an auger motor. The hose includes an inlet at a distal end and an outlet at a proximal end. The auger includes a shaftless helical blade having a portion that is radially enveloped by the hose. The vacuum system is adapted to suck material from the septic tank or pit latrine via the hose. The auger motor is adapted to rotate the auger about a helical axis in a first direction, in which the rotation about the helical axis in the first direction causes the shaftless helical blade of the auger to translate along the helical axis from the outlet of the hose towards the inlet of the hose.
US10130897B2	Contacting a gas stream with a liquid stream A co-current contacting system is described herein. The co-current contacting system includes a co-current contactor located in-line within a pipe. The co-current contactor includes an annular support ring configured to maintain the co-current contactor within the pipe and a number of radial blades configured to allow a liquid stream to flow into the co-current contactor. The co-current contacts also includes a central gas entry cone configured to allow a gas stream to flow through a hollow section within the co-current contactor, wherein the co-current contactor provides for efficient incorporation of liquid droplets formed from the liquid stream into the gas stream. The co-current contacting system also includes a separation system configured to remove the liquid droplets from the gas stream.
US10130896B2	Process for purifying hydrocarbons A process for washing hydrocarbons said process comprising: (I) distilling a crude acetone mixture preferably obtained from the cleavage of cumene hydroperoxide and containing hydrocarbons and water so as to form a bottoms fraction containing said hydrocarbons in an organic phase and an aqueous phase; (II) contacting at least a part of said bottoms fraction with an aqueous metal hydroxide solution so as to provide a concentration of 0.1 to 5 wt % MOH, where M is an alkali metal, in the aqueous phase; (III) separating the aqueous phase and the organic phase; (IV) contacting at least a part the organic phase from step (III) with an aqueous metal hydroxide solution so as to provide a concentration of 6 to 20 wt % MOH in the aqueous phase; (V) separating the organic phase and aqueous phase formed in step (IV); (VI) washing at least a part of the organic phase of step (V) with water.
US10130891B2	Video compression system and method for compensating for bandwidth limitations of a communication channel A system and method are described below for encoding interactive low-latency video using interframe coding. For example, one embodiment of a computer-implemented method for performing video compression comprises: detecting a maximum data rate of a communication channel between a server and a client; transmitting a video stream comprising a series of sequential frames from the server to the client; detecting that the maximum data rate will be exceeded if a particular frame of the sequence of frames is transmitted from the server to the client over the communication channel; and in lieu of transmitting the frame which could cause the maximum data rate to be exceeded, causing the client to re-render the previous frame of the sequence of frames, thereby effectively reducing the frame rate of the video stream rendered on the client.
US10130890B2	Game device Provided is a user interface having improved usability when, in a period in which information relating to a state of a game which is being executed by a game device is being distributed to another game device, users exchange messages regarding the game being distributed. The game device executes a game application, distributes the information relating to the state of the game being executed to the another game device, receives from a distribution-destination game device a message input by the user of the distribution-destination game device regarding the distributed information, and controls display means to display a game image representing the state of the game along with the received message.
US10130885B1	Viewport selection system Techniques for enabling selection of one or more viewports from a scene representation are disclosed herein. In some aspects, scene configuration information including a position of at least one viewport relative to the scene may be received. Each of the at least one viewport may be associated with a streaming camera view. A scene representation may then be defined based, at least in part, on the scene configuration information. One or more viewport representations corresponding to each of the at least one viewport may be positioned within the scene representation, based, at least in part on, the scene configuration information. The scene representation, including the at least one viewport representation, may be displayed, for example, to a user. Each viewport representation may allow the respective streaming camera view associated with the corresponding viewport may to be displayed, such as by selection of each viewport representation.
US10130879B2	Game system A game system is disclosed. The game system includes a computer, a display device and an operation device. The computer is configured to run a game, the display device is configured to display a game image, and the operation device is configured to input an operation command into the computer. A vibrator is provided in the display device and/or the operation device. The computer is further configured to send a vibration signal to the display device and/or the operation device according to game information, so as to drive the vibrator to generate vibration. According to the above game system, the display device and the operation device such as mouse or keyboard may generate vibration by means of the vibrator, according to game information, present vibration sensing and tactile for a player, thereby enabling the player to be more personally on the scene in the game.
US10130877B2	Remote gaming and projection Remote gaming and/or projection are provided. A first device includes a gaming system or presentations associated with its display. The features of the gaming system are accessed over a network and images associated with accessed features and/or associated with presentations of a host's display are then projected onto a client's display. The client and the client's display are remote from the host, the gaming system, and the host's display.
US10130876B2	Joystick module A joystick module includes a base, a joystick body, a joystick cover and a second protruding edge. The base includes a casing and a first protruding edge. A top part of the casing has an opening. The first protruding edge is formed on a periphery of the opening of the casing. The joystick body is installed in the base. A first end of the joystick body is protruded through the opening so as to be rotated. The joystick cover is installed in the base and connected with the joystick body. In response to a rotation of the joystick body, the joystick cover is correspondingly rotated. During the rotation of the joystick body, a part of the second protruding edge is contacted with an inner surface of the casing. When the part of the second protruding edge is contacted with a part of the first protruding edge, the rotation of the joystick body is limited.
US10130873B2	Method and apparatus for preventing a collision between subjects An apparatus for executing a computer game are provided. The apparatus includes an output unit configured to transmit a first image generated based on a form of a first user participating in the computer game and a second image generated based on a form of a second user participating in the computer game to a display apparatus, and a control unit configured to predict a possibility of a collision between the first user and the second user, and to control transmitting warning information indicating the possibility of the collision to the display apparatus via the output unit, according to a result of the predicting.
US10130872B2	Apparatus and method for matching groups to users for online communities and computer simulations A method includes detecting a first group seeking members, detecting one or more users seeking to join a group, retrieving group parameters corresponding to the first group, and retrieving user parameters corresponding to each of the one or more users. The group parameters may include group characteristic data and group requirements. For each user of the one or more users, the group parameters corresponding to the first group are compared against the user parameters corresponding to the user. A score is determined for each of the one or more users based on the comparing. One or more selected users of the one or more users is recommended to the first group at least in part based on the score. One or more computer programs may be adapted to execute the above steps, and a processor may be configured to perform the above steps.
US10130871B2	Crane teamwork building game A crane game is provided for amusement, training, and team building purposes. The body of the crane is suspended beneath manually held handles which are attached to the crane body by cords. Two lifting hooks are suspended beneath the crane body and operated by lifting lines which engage the crane body and extend outwardly from the crane body. Multiple persons each control a handle or lifting line and operate the crane through coordinated movement of the handles and lifting lines.
US10130866B2	Process and system for managing a bowling centre A process and a system for managing a bowling center, which includes one or more bowling lanes along which a bowl is rolled, one or more pin setting up machines at one end of the lane and one or more bowlers' bays at the opposite end of the lane, one or more overhead monitors or videos above the lane, one or more consoles or keyboards located at the one or more lanes, respectively, and allowing a user to enter data, an electronic control system set up to manage the bowling center, and in particular, a score program which calculates the score of the games played at the bowling center and displays the score, in particular at the respective overhead monitor. A visual signal is emitted at the respective lane to indicate that the lane is open and waiting for users.
US10130865B2	Micro adjustment mechanism for a pitching machine A machine for throwing balls is provided that can accurately adjust the vertical height or pitch and the lateral placement or yaw of balls being thrown. The machine includes a pitch housing, a threaded pitch adjustment shaft rotatably mounted to the pitch housing, a pitch yoke threadably mounted to the pitch adjustment shaft, a yaw housing to which the pitch housing is fixed, and a threaded yaw adjustment shaft rotatably mounted to the yaw housing. Also included is a yaw yoke mounted to the yaw housing and to the yaw adjustment shaft, and a stand to which the yaw housing is rotatably mounted.
US10130864B2	Cycling training apparatus with stationary movement A cycling training apparatus including a structure that is supported on the floor and a belt that is movable with respect to the structure and forms a closed longitudinal loop on which a bicycle can be supported and ridden. The apparatus includes a securing element with two opposite ends. One end has a first connector configured to be attached to a bicycle. The opposite end includes a second connector configured to be attached to a fixed point. The securing element is flexible so that the straight line distance between these ends is variable, enabling the bicycle to move longitudinally over the belt. The connectors also allow for transversal movement and lateral tilting of the bicycle.
US10130859B1	Training device with return This disclosure presents a training device and return for practice or game play so that when a ball is directed toward the target, the ball can either impact the target face or pass through one of a plurality of holes in the target face. The training device may be adjustable for use with different sized balls and the return may be automated.
US10130858B2	Composite golf club grip A golf grip for a golf club is disclosed herein. The golf grip includes a closed end, an open end, a composite shell including a laminate composite fiber material, a foam layer, and a shaft cavity. The foam layer is inward of the composite shell. The shaft cavity extends from the open end towards the closed end. The shaft cavity is inward from the composite shell and the foam layer. In embodiments, the golf grip also includes a core tube inward of the composite shell and of the foam layer. The core tube forms a shaft cavity for receiving a shaft of the golf club.
US10130857B1	Golf tee marking device The golf tee marking device can place a notch in a golf tee multiple times and at multiple heights, one height for drivers and another height for irons. The golf tee marking device comprising a housing for inserting and holding a golf tee, at least one lever having means for crimping said golf tee within said housing, when said lever is activated. Wherein said golf tee is positioned in said housing and said lever is activated by a user, said crimping means creates a notch on said golf tee to the correct height of the golf tee.
US10130856B2	Releasable and interchangeable connections for golf club heads and shafts Golf club heads are releasably engaged with shafts so that the club heads and shafts can be readily interchanged and/or so that the shaft position with respect to the club head can be readily changed. Assemblies for connecting the club head and shaft may include: a shaft adapter, a collet, a ferrule, and a club head having an interior chamber. The club head and shaft may be changed by releasing the securing system and exchanging the original parts with different parts.
US10130852B2	Golf club head having a detached faceplate A golf club head includes a body having a faceplate with a strike surface, a toe end opposite a heel end, a back end opposite the faceplate, and a sole opposite a top rail, the faceplate is connected to the sole and configured to pivot about the sole.
US10130845B2	Gymnastic machine, system, method, and program product for easily controlling the training of a user on a gymnastic machine Gymnastic machine usable by a user for a training, said user being provided with an electronic device wearable by the user and configured to receive commands by the user.The gymnastic machine comprises a main control unit configured to: receive from said electronic device, via a wireless-type data communication channel, an input command provided by the user to the electronic device; generate, based on the received input command, an operative command of the gymnastic machine; control the gymnastic machine based on said generated operative command. A system, a method, and a corresponding program product for the simplified control of the training of a user on a gymnastic machine are also described.
US10130840B2	Passive muscle training device and method for driving the same A passive muscle training device includes a base having at least one first link and at least one second link. At least one first rod is pivotably connected to the at least one first link. At least one second rod is pivotably connected to the at least one second link. The at least one first rod and the at least one second rod each have a handle extending beyond the cover on the base. A power input end is pivotably connected to the first rod and drives an eccentric portion of a shaft to swing the at least first rod and the at least one second rod alternatively. The user holds the two handles and the user's muscles are trained by centripetal contraction and centrifugal contraction due to the movement of the handles.
US10130838B2	Abdominal exercise assembly An abdominal exercise assembly for exercising abdominal muscles includes a plate that is rigid. The plate has a first end that is configured to insert between a mattress and a box spring of a bed. A second end of the plate is positioned proximate to an edge of the bed. A support is slidably coupled to the second end. The support is configured to position proximate to and parallel to the edge of the bed. A bar, coupled to the support distal from the plate, extends bidirectionally from the support in parallel with the second end of the plate. The bar is configured to be selectively vertically positioned relative to the plate. The plate is retained in a substantially horizontal configuration by a combination of the weight of the mattress and a user positioned on the mattress. The bar is configured to selectively position legs of a user.
US10130833B2	Reinforced filter media Reinforced filter media are prepared by adhering discrete, non-intersecting strands of thermoplastic or thermoset materials to the filter media web. The filter media may be a fabric, a nonwoven web or a filtering foam. The reinforced filter media can be used to prepare respirators, including flat-fold respirators or molded respirators.
US10130832B2	Automatic switchable exhale cartridge An exhale valve assembly includes a housing, a valve carrier body, a primary valve assembly, a plunger, a lock assembly, and an air pressure activated actuator assembly. The valve carrier body is disposed the housing and has a passageway. The primary valve assembly is mounted to the valve carrier body. A first air flow path passes through the passageway and a second air flow path passes through the primary valve assembly. The plunger is configured to permit a flow through the first air flow path when the plunger is in a first position and to direct a flow through the second air flow path when the plunger is in a second position. The lock assembly is configured to secure the plunger in the first position. The air pressure activated actuator assembly is configured to release the lock responsive to a pressure change within the cavity of the housing.
US10130831B2	Self-contained breathing system A breathing apparatus is operable in self-contained and filtered modes of operation. In the self-contained mode of operation, a breathable gas is delivered to a user from a self-contained source of breathing gas. In a second, filtered mode of operation, a suction source draws ambient air through a filter removing contaminants and delivers filtered ambient air to the user. A method of delivering air to a subject is also provided.
US10130824B2	Asystole detection and response in an implantable cardioverter defibrillator An implantable cardioverter defibrillator (ICD) receives a cardiac electrical signal by a sensing circuit while operating in a sensing without pacing mode and detects asystole based on the cardiac electrical signal. The ICD determines, in response to detecting the asystole, if asystole backup pacing is enabled, and automatically switches to a temporary pacing mode in response to the asystole backup pacing being enabled. Other examples of detecting asystole and providing a response to detecting asystole by the ICD are described herein.
US10130821B2	Interventional medical systems and associated tethering assemblies and methods An assembly for tethering a medical device to a delivery catheter includes a tether, a collet, and a spring-biased holding element that is coupled to a distal end of the tether and that extends around the collet, being moveable between first and second positions. At the first position, corresponding to the spring bias thereof, the holding element prevents fingers of the collet, which are configured to grip a proximal end of the device, from opening; at the second position, the collet fingers are allowed and/or caused to open. The assembly is coupled to a tubular member of the catheter, and, when the tethering assembly abuts a distal end of the catheter tubular member, a pull force applied to a proximal end the tether, which extends out from a proximal opening of the catheter, moves the holding element from the first position to the second position.
US10130816B2	Devices and methods to use power spectrum or signal association for pain management Methods and systems for electrical stimulation can include obtaining a biosignal of the patient; altering at least one stimulation parameter of an electrical stimulation system in response to the biosignal; and delivering an electrical stimulation current to one or more selected electrodes of the electrical stimulation system using the at least one stimulation parameter. In some embodiments, a power spectrum is determined from the biosignal. In some embodiments, the biosignal is at least two different biosignals measured at the same or different locations on the patient and a coherence, correlation, or association between the two biosignal is determined.
US10130814B2	Movement disorder A method of treating a movement disorder using deep brain stimulation, the method comprising the step of inserting a lead having at least one electrode into the brain of a subject, the lead being inserted along a trajectory from the occipito-temporal or occipito-parietal regions, passing laterally to the posterior horn of the lateral ventricle to contact the subthalamic nucleus, the zona incerta or the globus pallidus.
US10130813B2	Seizure onset classification and stimulation parameter selection A neurostimulation system senses electrographic signals from the brain of a patient, extracts features from the electrographic signals, and when the extracted features satisfy certain criteria, detects a neurological event type. A mapping function relates the detected neurological event type to a stimulation parameter subspace and a default stimulation parameter set where the values of the stimulation parameters define an instance of stimulation therapy for the patient. The decision whether to implement a stimulation parameter subspace or a default stimulation parameter set may be informed by integrating other information about a state of the patient. A stimulation parameter subspace or stimulation parameter set may optimized by testing it against various thresholds until certain effectiveness criteria is satisfied. The neurological event type may be one of several electrographic seizure onset types.
US10130806B2	Systems and methods for making and using a temporary lead A trial electrical stimulation lead includes a lead body having a distal end portion, a proximal end portion, and a longitudinal length; electrodes disposed along the distal end portion of the lead body; terminals disposed along the proximal end portion of the lead body; conductors electrically coupling the terminals to the electrodes; and a preventer extending proximally from the proximal end portion of the lead body. The preventer has a diameter smaller than a diameter of the lead body. The preventer prevents coupling of the trial electrical stimulation lead to an implantable control module, but permits coupling to an external trial stimulation system.
US10130804B2	Syringe—IV access locking device A safety device is described wherein drug delivery systems and methods involve associating unique keys to patients that prevent the interconnection between a drug delivery device and non-complimentary patient key. Medication in a drug delivery device intended for a patient may only be accessed via a particular unique key associated with the intravenous access device of that patient.
US10130800B2	Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof The present specification disclosed a noninvasive transdermal delivery device that relates generally to a handheld mechanical apparatus for noninvasive transdermal administration of gas, small to large water-soluble (hydrophilic) pharmaceutical agents, vitamins, and other therapeutic agents. Components of such delivery devices, methods of producing a substance comprising a supersaturated amount of a dissolved gas, as well as, methods of administering a therapeutic agent using such delivery devices and methods of treating a disease or condition using such delivery devices are also disclosed.
US10130799B2	Inflator with varying mechanical advantage An inflator comprises a body, a first drive member, and a second drive member. The body defines a reservoir that is configured to hold fluid and includes an outlet. The first drive member is operable to move through the reservoir to drive fluid from the reservoir through the outlet. The second drive member is engaged with the first drive member. The second drive member is movable relative to the body through a first range of motion to actuate the first drive member to drive fluid through the outlet at a first rate. The second drive member is movable relative to the body through a second range of motion following the first range of motion. The first drive member is configured to either drive fluid through the outlet at a second rate or not drive fluid through the outlet as the second drive member moves through the second range of motion.
US10130796B2	Guide wire and method for manufacturing a guide wire A guide wire includes an elongated core wire possessing a distal portion at which is located a reshaping portion that is configured to be reshaped. The reshaping portion includes a first material portion made of a first material and a second material portion which is made of a second material different than the first material. The first material portion is joined to the second material portion at a joint surface which extends in the longitudinal direction of the core wire.
US10130795B2	Catheter apparatus with telescoping lumen catheters and its use in methods for treating vasculatures The invention provides for methods and catheter apparatus for passing one or more guidewires (via the use of one or more telescoping guidewire lumens) through a chronic total occlusion of a vasculature. The catheter apparatus may include: a catheter shaft having a distal end; one or more telescoping guidewire lumen catheters passing longitudinally through the shaft, wherein the one or more guidewire lumen catheters are capable of telescoping beyond the distal end of the catheter shaft; an expansible distal portion of the shaft; and a retractable sheath covering at least a portion of the expansible distal portion of the shaft, wherein retracting the retractable sheath from the expansible distal portion of the shaft directly activates the expansible distal portion of the shaft causing expansion of the expansible distal portion of the shaft.
US10130791B2	Catheter and introducer catheter having torque transfer layer and method of manufacture The instant invention relates generally to catheters and to introducer catheters used to help deliver catheters or other medical devices to locations within the human body. In particular, the instant invention relates to large diameter catheters and introducer catheters having a torque transfer layer that includes at least two flat wires braided into a wire mesh. The flat wires have a width of at least about 0.007 inches and a depth of at least about 0.003 inches. The lumen diameter of the catheter is at least about 6 French. The torque transfer layer provides increased strength, flexibility, and kink resistance.
US10130787B2	Humidity controller A breathing assistance apparatus adapted to deliver humidified gases at a desired level of humidity to a patient including a humidifier and a heated conduit is disclosed. The humidifier includes a controller which controls the humidifier, or the humidifier and the heated conduit to deliver the gases to the patient at the required humidity or temperature, without the requirement for sensors in the gases stream. The controller uses information already available to the controller, without the requirement for additional information to be provided by sensors in the gases stream. This means the need for sensors in the gases stream is dispensed with. A significant benefit is achieved as sensors are not required in the conduit and thus the apparatus is simple and less bulky.
US10130786B2	Nebulizer mouthpiece for reducing drug loss A method for reducing a loss of medication from a nebulizer includes the steps of entraining a liquid medication into a first flow of a pressurized gas into a nebulizer chamber and also entraining an additional amount of the liquid medication into a second flow of ambient air drawn into the nebulizer chamber through an opening when a patient inhales through the nebulizer chamber. When the patient exhales, a portion of the exhaled breath is directed into the outlet of the nebulizer chamber, thereby increasing a backpressure within the outlet and substantially stopping the second flow of ambient air into the nebulizer chamber, thereby decreasing the amount of medication lost to the ambient environment while the patient is not inhaling.
US10130785B2	Nasal mask system An elbow for a respiratory mask includes a mask connection end adapted to connect to the mask and a tube connection end adapted to connect to an air delivery tube that delivers breathable gas to a patient. The mask connection end includes a first region constructed of a more rigid material and a second region constructed of a more flexible material. The second region provides flexibility to one or more portions of the mask connection end to enable engagement and disengagement of the elbow with the mask and/or sealing of the elbow with the mask.
US10130781B2	Compressible connector for an inner cannula A tracheal tube assembly includes an outer cannula configured to be positioned in a patient airway and an inner cannula configured to be disposed inside the outer cannula. The tracheal tube assembly further includes a flange member secured about the outer cannula, and an outer cannula connector coupled to a proximal end of the outer cannula. The inner cannula includes a compressible proximal end region that is compressed while secured inside the outer cannula connector.
US10130775B2	Medicament delivery device A medicament delivery device includes a housing having distal and proximal ends along a longitudinal axis. The housing is arranged to accommodate a medicament container and a delivery member connected to the container; a reloadable drive mechanism for acting on an accommodated container; a delivery member cover at the proximal end and slidable in relation to the housing along the axis; and a cover lock mechanism that includes a first lock member on an actuator movably arranged in relation to the housing and a second lock member on the cover. The first lock member engages the second lock member to block movement of the cover, and the actuator is movable in relation to the cover such that manually actuating the actuator generally transverse to the axis causes the first lock member to be moved out of engagement with the second lock member, thereby allowing the cover to be moved.
US10130772B2	Injection device A handheld injection device includes a housing, a rotatable dose setting member and a power reservoir coupled to the dose setting member. Energy is stored in the power reservoir during rotation of the dose setting member. The injection device also includes a release member for receiving a force from a user and a rotatably arranged drive member engaging with a drive track of a piston rod. The device further includes a release clutch rotationally constrained to the housing and releasably engaging the drive member. The release clutch is positionable in a first axial position when the release member is in a dose setting position and in a second axial position when the release member is in a dose injection position. The axial position of the drive member within the housing remains constant when the release member is in its dose setting position and in its dose injection position.
US10130771B2	Syringe barrel and mold for injection molding A syringe barrel includes a hollow barrel portion that has a proximal-end opening at a proximal end of the barrel portion and is configured such that a gasket is insertable from the proximal-end opening into the barrel portion. An inner peripheral portion of the barrel portion includes a tapered portion in a main area of the inner peripheral portion in an axial direction, the tapered portion having an inner diameter that gradually increases toward a distal end of the tapered portion from a proximal end of the tapered portion.
US10130768B2	Combination plunger device for a dual chamber mixing syringe A combination plunger, a mixing device and a mixing syringe including the same are provided. The mixing syringe includes concentric outer and inner barrels that form an outer chamber, the inner barrel having an inner chamber. The combination plunger includes a mixing plunger and a delivery plunger and a biasing means. The mixing plunger is slidably located in the outer chamber and translated by coordinated depression of the delivery plunger to transfer a first substance from the outer chamber to mix with a second substance in the inner chamber. After the mixing stage is complete, the delivery plunger is disengaged from the mixing plunger and permitted, such as by rotation, to be further depressed in the axial direction to deliver fluid contents of the mixing syringe to a recipient. The mixing syringe needle is then retracted as result of engagement by the delivery plunger and activation of the biasing means.
US10130765B2	Integrated insulin delivery system having safety features to prevent hypoglycemia Safety features are applied to an integrated insulin delivery system to enhance safety by controlling medication delivery including the automatic resumption of basal rate after a particular event, such as termination of a bolus, expiration of a time period, delayed resumption after the bolus has terminated, IOB comparison, and others. Other safety features include overriding a delivery control that may result in hypoglycemia, and terminating an extended bolus or temporary basal rate in view of a glucose signal indicating imminent carbohydrate deficiency. In another feature, an automatic resumption of a basal delivery rate is programmed into the delivery device to avoid the possibility of complete loss of delivery of insulin in the event that communication with the delivery device is disrupted.
US10130764B2	Pump and monitor for IV pressure bag infusers A pumping device that can be used with currently-available pressure bag infusers is disclosed. The pumping device is hand-held and lightweight. The device is controlled by a microprocessor. Thus constant pressure to the bag is maintained through automatic adjustment of pumping and venting functions. In addition, a novel, new pressure bag infuser and a modified Luer Lock fitting for use with the pumping device are described.
US10130761B2	Infusion systems An infusion system comprises an infusion set (30) with one or more advanced features including tube set strain relief (10), infusion pumps having heat exchange abilities and two-direction pumping abilities (100), Piezo pump devices (200), reservoirs (220, 240) made from expanded tubing, and oil impregnated pump plungers (302). An exemplary strain relief (10) includes an adhesive layer (12) such as pressure sensitive adhesive (PSA) secured to a base (14). The base (14) rotatably receives a pin (18) of a tube holder (16). The pin (18) is captured within an opening (22) of the base (14) to allow 360 degree rotation of the tube holder (16).
US10130758B2	Fluid delivery device, transcutaneous access tool and insertion mechanism for use therewith A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir, the transcutaneous access tool including a needle or a trocar; and a transcutaneous access tool insertion mechanism for deploying the transcutaneous access tool, wherein the insertion mechanism is configured to insert and retract the needle/trocar in a single, uninterrupted motion.
US10130755B2	Devices and methods for delivering a beneficial agent to a user Device for delivering a beneficial agent includes a cassette including a cassette housing with a fluid reservoir and a cassette base region. The device also includes a delivery tube. The device also includes a pump including a pump housing containing a pump assembly having a fluid drive component. The pump housing has a receiving region to receive the cassette base region. The fluid drive component is proximate the receiving region. A lock member is coupled to the pump housing and movable between an open position and a closed position. The cassette is capable of being inserted into and removed from the receiving region when the lock member is in the open position, and the cassette is secured to the pump with the cassette base region within the receiving region and the delivery tube in operative engagement with the fluid drive component when the lock member is in the closed position.
US10130751B2	Membrane separation and washing devices, systems and methods employing same, and data management systems and methods A method of separating blood into two or more components and subsequently washing a component, comprising providing a blood storage container containing an initial blood composition, and a blood separation circuit comprising a separator. The method also comprises separating and washing cellular material within the same blood separation circuit.
US10130749B2	Medical device for extracorporeal blood treatment comprising plural sensor units The invention relates to a medical device for extracorporeal blood treatment comprising an extracorporeal blood circulation having at least one tube and at least two sensor units measuring on the tube with different operating principles, wherein portions of the tube are adapted to be coupled to the at least two sensor units for measurement. According to the invention, each sensor unit consists of a sensor-specific component and a sensor-neutral component, wherein the sensor-neutral components of the sensor units are formed to be identical whereas the sensor-specific components are different in response to the operating principle and comprise a respective specific sensor system. Furthermore, for each sensor unit a sensor-neutral component is mounted on a sensor-specific component, wherein when being introduced and fixed in a sensor-neutral component a portion of the tube is adapted to be coupled to the sensor system of the sensor-specific component located there beneath so that the sensor system can carry out a measurement at the tube.
US10130746B2	Filtration system for preparation of fluids for medical applications Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed through a first filtration step which is effective for creating purified water and a pair of ultrafilters placed at the outlet. The ultrafilters are separated by an intervening flow path to prevent grow-through from the outlet end upstream. In embodiments, a recirculation path with an air removing filter helps to eliminate air from the ultimate product water.
US10130740B2	Pressure control during processing of adipose tissue An adipose tissue (AT) transfer system includes, on the aspiration side, an aspiration cannula, an aspiration pump, a container, and flexible tubing connecting the aspiration cannula to the container. On the reinjection side, the system includes a reinjection cannula, flexible tubing connecting the inlet of the reinjection cannula to the container, and a reinjection pump imposing positive-displacement pumping action on the flexible tubing and causing movement of AT in a continuous or pulsed mode. The aspiration pump operates to continually supply harvested AT to the second flexible tubing while the reinjection pumps causes continuous or pulsed deposition of the AT at the injection site. To ensure that internal pressure and/or flow of the AT through a channel of delivery of the AT to the reinjection site does not exceed a predetermined value, the system contains an external pressure sensor configured to measure such internal pressure in absence of a part that is in direct contact with the AT.
US10130736B1	Tissue-derived tissuegenic implants, and methods of fabricating and using same The disclosure provides implants containing a plurality of particles containing at least one population of viable osteogenic cells adherent to and resident in an osteoconductive matrix or at least one viable population of osteogenic cells caused to be in contact with the osteoconductive matrix; methods of fabricating the implants; and use of the implants in bone repair. The implant further contains an osteoinductive component. An example of an osteoinductive component is a demineralized bone matrix in the form of particles or fibers.
US10130731B2	Mobile device holder and powered air freshener Technologies are generally described for apparatuses and methods relating to a mobile device holder and air freshener. The mobile device holder and air freshener may include a body, a fastening component, a removable cap, a flexible arm, and a mount. The fastening component may secure a mobile electronic device to the apparatus. The removable cap may allow scented material to be installed within the body. The fastening component may secure a mobile electronic device to the apparatus. The flexible arm may be coupled to the body at a first side and the mount on a second side. The mount and the flexible arm may support the mobile electronic device. The body may allow air that has entered the apparatus through a first vent of the apparatus to become scented and flow out of the apparatus through a second vent of the apparatus.
US10130729B2	Scented odor reducing composition An odor reducing composition comprising a scent and silver nanoparticles is disclosed, together with methods of making and using the same, and methods for reducing an odor.
US10130728B2	Systems and methods for controlling humidity Systems and methods for controlling humidity. Methods can include providing a chamber configured to receive objects to be sterilized; injecting a first quantity of water into the chamber; determining a pressure rise and a pressure drop in the chamber resulting from the first injection; calculating an absorption ratio (AR) as the ratio of the pressure drop to the pressure rise; sensing the humidity of the chamber after the first injection to determine a first humidity value (RHchamber); comparing the first humidity value to a pre-selected humidity value (RHsetpoint) to determine a humidity error (RHerror), wherein RHerror=RHsetpoint−RHchamber; and injecting a second quantity of water into the chamber, wherein the second quantity of water is calculated based on the absorption ratio (AR) and the humidity error (RHerror). Systems can perform the method; and the systems and methods can be employed in a sterilizer.
US10130725B2	Method for labeling exosomes with radioactive substance and use thereof A method for labeling exosomes with a radioactive substance using an amine group on surfaces of the exosomes includes providing a cell-derived exosome, treating a surface of the exosome with N-hydroxysuccinimide-azadibenzocyclooctyne (NHS-ADIBO), and mixing the treated exosome with N3-introduced chelator-radioactive substance to conduct a reaction between the chelator and an amine group present on the surface of the exosome, wherein the radioactive substance is introduced inside the exosome by the above reaction. The exosomes can be stably labeled at high labeling efficiency, and the exosomes can be favorably used as an agent for nuclear medicine imaging and therapeutic imaging for confirming the biological distribution of exosomes and whether the exosomes move to target organs and target diseases in animals including a human being.
US10130724B2	Mini-gastrin analogue, in particular for use in CCK2 receptor positive tumour diagnosis and/or treatment A gastrin analog shows high uptake in CCK-2 receptor positive tumors and simultaneously a very low accumulation in the kidneys. This is achieved by a mini-gastrin analog PP-F11 having the formula: PP-F11-X-DGlu-DGlu-DGlu-DGlu-DGlu-DGlu-Ala-Tyr-Gly-Trp-Y-Asp-Phe-NH2, wherein Y is an amino acid replacing methionine and X is a chemical group attached to the peptide for diagnostic and/or therapeutic intervention at CCK-2 receptor relevant diseases. Very suitable compounds with respect to a high tumor to kidney ratio are mini-gastrin analogs with six D-glutamic acids or six glutamines. These compounds still possess a methionine which can be oxidized easily which is a disadvantage for clinical application under GMP due to the forms which may occur. The elimination of the methionine leads to a lower affinity to oxidation which in general favors the tumor-kidney-ratio. Ideally, the methionine is replaced by norleucine. This PP-F11N mini gastrin exhibits currently the best tumor-kidney-ratio and is the most promising candidate.
US10130720B2	Composition comprising a polymeric reagent The present invention provides conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates. The conjugates as well as the polymeric reagents used to form the conjugates include at least one of each the following: an aromatic moiety comprising an ionizable hydrogen atom, a spacer moiety, and a water-soluble polymer. Methods of making polymeric reagents and conjugates, as well as methods for administering conjugates and compositions, are also provided.
US10130716B2	Zwitterionic polymer bioconjugates and related methods Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates.
US10130713B2	Cocrystalline DHEA formulations A cocrystalline DHEA composition with at least one additional coformer is disclosed for therapeutic formulations. The cocrystalline DHEA/coformer formulation including at least one coformer chosen from the group consisting of glutaric acid, maleic acid, tartaric acid, fructose, and wherein the L-isomer of tartaric acid and the D-isomer of fructose are utilized. The cocrystalline DHEA/coformer formulations include certain excipients as a solubilizer or inhibitor.
US10130711B2	Chemical structures for localized delivery of therapeutic agents The present invention provides a method for selective delivery of a therapeutic or diagnostic agent to a targeted organ or tissue by implanting a biocompatible solid support in the patient being linked to a first binding agent, and administering a second binding agent to the patient linked to the therapeutic or diagnostic agent, such that the therapeutic or diagnostic agent accumulates at the targeted organ or tissue.
US10130710B2	Formulation and method for producing same An object is to provide a formulation that includes a particle containing an active ingredient and a surfactant, and a base, and is more excellent in storage stability. For solution, a formulation including a particle containing an active ingredient and a surfactant, and a base, in which the surfactant is contained in a ratio of 5 to 100 parts by weight based on 1 part by weight of the active ingredient, is provided.
US10130707B2	Topical pharmaceutical composition based on semifluorinated alkanes The invention provides liquid or semi-solid pharmaceutical compositions for topical administration comprising a semifluorinated alkane. The compositions are useful for the delivery of active ingredients into the deep layers of the skin or skin appendages. Various active ingredients may be incorporated, such as immunosuppressants, antiinfectives, antifungal agents, antiinflammatory agents, and retinoids.
US10130705B2	Vaccines with interleukin-33 as an adjuvant Disclosed herein is a vaccine comprising an antigen and IL-33. Also disclosed herein is a method for increasing an immune response in a subject in need thereof. Further disclosed herein is a method for treating cancer in a subject in need thereof. The methods may comprise administering the vaccine to the subject.
US10130699B2	Vaccine against Lawsonia intracellularis and porcine circovirus 2 The present invention pertains to a vaccine comprising in combination killed whole cell Lawsonia intracellularis bacteria and porcine circo virus 2 (PCV2) ORF2 protein for use in protecting a pig against an infection with Lawsonia intracellularis and PCV2 by an intradermal administration of the vaccine. The invention also pertains to a method to protect a swine against an infection with Lawsonia intracellularis bacteria and PCV2.
US10130697B2	Vaccines comprising mutant attenuated influenza viruses The invention provides a vaccine comprising an effective amount of an isolated recombinant influenza virus comprising a mutant M gene segment that is mutated so that upon viral replication the mutant M gene expresses a functional M1 protein and a mutant M2 protein with a deletion of the cytoplasmic tail and either lacking a transmembrane domain or having a mutated transmembrane domain.
US10130695B2	Compositions containing combinations of bioactive molecules derived from microbiota for treatment of disease Compositions consisting of bioactive molecules derived from the microbiota of a mammal are provided herein. When administered orally with a colonic delivery system, the compositions are useful for the prophylaxis and treatment of diseases, in particular inflammatory, autoimmune and infectious diseases. The compositions comprise combinations of small molecules and bacterial antigens formulated in colonic delivery systems. Use of the compositions results in any or all of: induction of immune tolerance; strengthening of the gut mucosal barrier integrity; reduction of inflammation; and amelioration of a disease state caused by inflammation, an autoimmune reaction or an infectious agent.
US10130686B2	Method and composition of thyroid hormone analogues and nanoformulations thereof for treating inflammatory disorders Thyroid hormone antagonists and their nanoparticle formulations (Nanotetrac™ or Nanotriac™) act at a cell surface receptor to block angiogenesis and tumor cell proliferation. The complex anti-angiogenic performs actions on specific cytokines and chemokines. Thyroid hormone antagonists inhibit expression in tumor cells of cytokine genes, e.g., specific interleukins, and chemokine genes, such as fractalkine (CX3CL1), and chemokine receptor genes (CX3CR1) that are targets in the development of inflammation-suppressant drugs. This application discloses a novel composition of Tetra or Tri-iodothyroacetic acid (tetrac or triac), other thyroid partial agonists or antagonists and their nanoparticle formulations conjugated to polymers and encapsulating non-steroidal anti-inflammatory, anti-inflammatory glucocorticoids, and/or polyphenols for the management of various acute and chronic inflammatory disorders ranging from neurological, vascular, and musculoskeletal disorders.
US10130684B2	Oral dissolving films for insulin administration, for treating diabetes Provided are orally administrable thin film dosage forms adapted to adhere to a mucosal tissue of a patient, wherein said film comprises mixtures of polymers and insulin.
US10130678B2	Systems and methods for improved delivery of osteoinductive molecules in bone repair Systems and methods for preparing synthetic osteoinductive bone grafts are provided in which a porous ceramic granule, which may be incorporated within a biocompatible matrix material, is loaded with an osteoinductive agent. Loading of granules is facilitated in some cases by the use of low-pH buffers and pre-treatments.
US10130677B2	Antimicrobial peptide and uses thereof The invention relates to antimicrobial peptides, pharmaceutical compositions comprising the peptides and to uses thereof for in the treatment or prevention of microbial, bacterial, fungal, viral and parasitic infection.
US10130676B2	Therapeutic peptides for cerebrovascular diseases The present invention provides a method for treating or ameliorating cerebrovascular diseases in a subject by using peptides isolated from extracts from rabbit skin inflamed by vaccinia virus. The present invention also provides a peptide comprising an amino acid sequence having at least 70% identity to SEQ ID NO: 1, or variants, mutants, derivatives, or fragments thereof.
US10130675B2	Wound healing agent The present invention aims to provide a wound healing agent that inhibits bacterial growth, promotes granulation tissue formation and epithelization, and minimizes foreign body reaction in the granulation tissue. The wound healing agent of the present invention contains protein (A) and water, wherein the protein (A) contains: GAGAGS (1); and an amino acid sequence (X) and/or an amino acid sequence (X′), and the total percentage of β turns and random coils in the protein (A) as determined by circular dichroism spectroscopy is 60 to 85%, and the percentage of the total number of amino acid residues in the amino acid sequences (X) and (X′) is 50 to 70% of the total number of amino acid residues in the protein (A). Amino acid sequence (X): at least one amino acid sequence selected from the group consisting of VPGVG (2), GVGVP (3), and GAHGPAGPK (4). Amino acid sequence (X′): an amino acid sequence in which 1 or 2 amino acid residues in the amino acid sequence (X) are independently replaced by a lysine (K) or arginine (R) residue.
US10130670B2	Composition for treating or preventing inflammatory skin disease, comprising, as active ingredient, immature citrus fruit extract, or synephrine or salt thereof The present invention relates to a composition for treating or preventing an inflammatory skin disease, comprising, as an active ingredient, an unripe Citrus unshiu fruit extract and/or Synephrine or salt thereof. The composition of the present invention prevents an inflammatory reaction by inhibiting activity of STAT6, expression of eotaxin-1 and an agglomeration function of eosinophil, and thus, shows effects of preventing and treating an allergic inflammatory disease, atopic dermatitis, eczema, psoriasis, etc. Also, the composition of the present invention does not have cytotoxicity and a skin side effect, and thus, can be safely applied to pharmaceutical products and cosmetics.
US10130669B2	Method and system for treating wounds A method and a system comprise receiving an amount of a first disinfecting solution on and around a wound. An amount of a second disinfecting solution is received on and around the wound. An amount of a third disinfecting solution is received on and around the wound. An amount of a fourth disinfecting solution is received around the wound. Cold laser emissions are received on and around the wound. The cold laser emissions comprise at least multiple wavelengths. A sterile gauze bandage and wrap cover the wound.
US10130665B2	Method for identifying bacteria for bacteriotherapy A method, for the identification of bacterial isolates suitable for use in bacteriotherapy, the method comprising: (i) preparing a suspension of material collected from a host harboring microbiota; (ii) addition of an activator of bacterial spores sufficient to allow growth of bacteria from spores present in the suspension; (iii) culturing the suspension; and (iv) identification of at least one bacterial species within the culture.
US10130661B2	Devices for wound healing The present invention provides devices and methods for improving wound healing, in particular, in diabetic subjects.
US10130657B2	Formulation, apparatus, and methods for treatment of brain trauma A formulation comprising platelet rich plasma (PRP) for treatment of patients who have experienced brain injury, consisting of a mixture of human autologous plasma, D5W, glutathione, methylcobalamin, and regular insulin. The formulation is infused directly adjacent to a patient's brain through the nostrils or nares of the nasal cavity. Treatment using the formulation may be supplemented with one or more therapies including hyperbaric oxidation therapy (HBOT), cranial osteopathic therapy, intravenous (IV) nutrition, electroencephalographic (EEG) biofeedback, low level laser therapy (LLLT), transcranial magnetic stimulation (TMS), adult stem cell treatments, and a ketogenic diet and medium-chain triglyceride (MCT) oil therapy.
US10130656B2	Mineral pitch resin manufactured under a safe and low temperature procedure A manufacturing method of mineral pitch resin, which comprises the steps of identification of the mineral, collection of the mineral, and processing of the mineral in a temperature controlled clean room facility by dissolving, filtering and demoisturizing. This method produces a resin which is verifiably free from harmful contaminants and is safe for humans to consume as a healing, tonifying and adaptogenic substance.
US10130655B2	Composition and method for pre-surgical skin disinfection This invention provides a pre-surgical disinfecting composition that includes at least about 50 percent by weight of a C1-6 alcohol, based upon the total weight of the disinfecting composition, an acid, and a cationic oligomer or polymer. A method for pre-surgical skin disinfection with rapid antiseptic efficacy without the use of secondary antimicrobial compounds is also described.
US10130654B2	Method of inducing osteogensis and promoting osseointegration around an implant The invention relates to a method of inducing osteogenesis in a subject comprising administrating a chitosan material to the a subject in need of osteogenesis, wherein the chitosan material having a chitosan with a degree of deacetylation at the range of 70%˜90%, and the chitosan is 0.15% by weight of the chitosan material. The method of the present invention can induce bone-forming and promote osseointegration around an implant.
US10130651B2	RNAi Therapy for Hepatitis B Virus Infection Described are compositions and methods for inhibition of Hepatitis B virus gene expression. RNA interference (RNAi) triggers and RNAi trigger conjugates for inhibiting the expression of Hepatitis B virus gene are described. Pharmaceutical compositions comprising one or more HBV RNAi triggers optionally with one or more additional therapeutics are also described. Delivery of the described HBV RNAi triggers to infected liver in vivo provides for inhibition of HBV gene expression and treatment.
US10130646B1	Calcium gluconate solutions in flexible containers A terminally sterilized aqueous calcium gluconate solution comprising 1 to 15 wt. % calcium gluconate and from 1 to 19 wt. parts of calcium saccharate per 100 wt. parts of calcium gluconate packaged in a flexible plastic container with the remainder water.
US10130644B2	Concentrated therapeutic phospholipid compositions The invention relates to concentrated therapeutic phospholipid compositions; methods for treating or preventing diseases associated with cardiovascular disease, metabolic syndrome, inflammation and diseases associated therewith, neurodevelopmental diseases, and neurodegenerative diseases, comprising administering an effective amount of a concentrated therapeutic phospholipid composition.
US10130639B1	Homogeneous ophthalmic composition This application is directed to a homogeneous solution of an aqueous, topical composition useful for the treatment of infection and/or for the treatment of inflammation due to trauma to tissue. Specifically, this application relates to a homogeneous, aqueous composition of a quinolone antibiotic and an anti-inflammatory agent.
US10130635B2	Process for preparation of optically pure and optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives and their use in preparing pharmaceuticals The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives represented by formula (IA) and (IB), processes for preparing the alcohol derivatives and their use in preparing pharmaceuticals.
US10130632B2	Methods for treating renal disease The invention features methods for treating or reducing the likelihood of developing a renal disease by administering to a subject in need thereof an agent that decreases expression of a pathogenic APOL1. The agents of the method target various signaling pathways and decrease the level of the pathogenic APOL1 polypeptide.
US10130630B2	BTK inhibitors The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts or stereoisomers thereof, or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula (I) in the treatment of Btk mediated disorders.
US10130629B2	Pharmaceutical combinations A pharmaceutical combination comprising N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, or a pharmaceutically acceptable salt thereof, and at least one active ingredient, as defined herein, or a pharmaceutically acceptable salt thereof, and optionally a pharmaceutically acceptable carrier, for simultaneous or sequential administration; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.
US10130626B2	Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to EGP-1 (TROP-2), CEACAM5, CEACAM6, CD74, CD19, CD20, CD22, CSAp, HLA-DR, AFP or MUC5ac and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 24 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy.
US10130625B2	Linked diaryl compounds with anticancer properties and methods of using the same Provided are compositions comprising linked diaryl compounds that possess anticancer properties. Methods of use are also disclosed herein. The method comprises administering an effective amount of a compound described herein to an individual in need thereof.
US10130622B2	Compounds for treatment of cystic fibrosis A corrector agent capable of stabilizing a newly synthesized cystic fibrosis transmembrane conductance regulator (CFTR) protein, useful in the treatment of cystic fibrosis.
US10130615B2	Benzomorphan analogs and the use thereof In one aspect, the invention provides compounds of Formula (I) or (II): (I) or (II) and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2a, R2b, R3, R4, Z and G are defined as set forth in the disclosure. The invention also provides compounds of Formulae A and B and pharmaceutically acceptable salts and solvates thereof. Other aspects of the invention include the use of compounds of Formulae I, II, A, and B, and pharmaceutically acceptable salts and solvates thereof for the treatment of disorders responsive to modulation of one or more opioid receptors. In certain embodiments, the Compounds of the Invention are useful for treating pain.
US10130613B2	Methods of treatment for cholestatic and fibrotic diseases The present invention relates to the compound [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) or 2-hydroxy-N-(5-nitro-2-thiazolyl)benzamide (Tizoxanide) for treating cholestatic and fibrotic diseases.
US10130605B2	Compositions for use in treating inflammatory bowel diseases and intestinal colitis Compositions for use in treating and/or alleviating a symptom of inflammatory bowel disease, colitis, and/or enterocolitis in a subject in need thereof are disclosed. The composition comprises a therapeutically effective amount of an anthraquinone derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable vehicle. In one embodiment, the composition comprises diacerein. Also disclosed is a first composition comprising an anthraquinone derivative selected from the group consisting of diacerein, aloe-emodin, emodin, and rhein, and a first pharmaceutically acceptable vehicle; and a second composition comprising mesalazine, and a second pharmaceutically acceptable vehicle, in combination for use in treating and/or alleviating a symptom of inflammatory bowel disease, colitis, and/or enterocolitis.
US10130596B2	Composition for reducing frequency of urination, method of making and use thereof Pharmaceutical compositions for reducing frequency of urination are disclosed. The pharmaceutical compositions comprise one or more prostaglandin pathway inhibitors and a pharmaceutically acceptable carrier. Also disclosed are methods of making and using the pharmaceutical compositions.
US10130594B2	Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogs for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analog or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
US10130579B2	Cosmetic material A cosmetic material comprises (A) a hydrophobic powder; (B) a carboxylic acid modified silicone; (C) a basic compound; and (D) water. The (A) hydrophobic powder is generally dispersed in an aqueous phase of the cosmetic material. The cosmetic material can provide a refreshing sense of feel during use, and can form a cosmetic film with excellent water resistance on the skin.
US10130578B2	Topical delivery of skin compositions having low pH Low pH compositions for topical administration to skin are provided. They comprise a buffering agent having a pKa of about 2.8 to about 4.2 and a cosmetically acceptable active ingredient having a pKa within about 1 unit of the pKa of the buffering agent. The composition has a pH of about 3.3 to 4 and a buffer capacity of at least about 0.15. A method of increasing the topical delivery of a cosmetically acceptable active ingredient having a pKa of about 2.8 to about 4 is also provided.
US10130574B2	Nitrone inhibition of oxidation of unsaturated fats Provided are compositions useful for inhibiting oxidation of unsaturated fats comprising an antioxidant compound of Formula I: wherein R, R1, R2, R3, R4, R5 and R6 are as defined herein.
US10130573B1	Composition and method of treating skin conditions The present invention is a composition and method of treatment for skin disorders, conditions, and severe skin dryness in general through topical systematic and periodic application of a formulation that generally may include salicylic acid, glycolic acid, urea, dimethyl isosorbide, ethoxydiglycol, barrier repair agents, anti-irritants, humectants, and also has an acidic pH formulation.
US10130572B2	Apparatus and methods for concealing vitiligo A method for concealing vitiligo is provided. The method comprises depressing a spring head. The spring head may be covered by a covering. Depression of the spring head may saturate the covering with a solution. The solution may include a bronzer and dihydroxyacetone (“DHA”). The method may also comprise guiding the saturated covering over a portion of depigmented skin.
US10130571B2	Dentifrice Comprising Zinc-Amino Acid Complex and Phosphates Disclosed herein are dentifrices comprising a zinc amino acid complex together with soluble phosphate salts. Methods of making and using the dentifrices are also provided.
US10130561B2	Functionalized calcium phosphate hybrid systems for confectionery and foodstuff applications A method for repairing dentition, including milling beta tricalcium phosphate with sufficiently high energy to substantially distressed its lattice structure, mechanochemically chelating an edible acid thereto to yield functionalized calcium phosphate moieties, and incorporating the functionalized calcium phosphate moieties into an edible material to yield a calcium phosphate delivery system. The calcium phosphate delivery system is introduced into an oral environment and dentition is repaired. The functionalized calcium phosphate moiety is characterized by weakly bonded fumaric acid at least partially wrapped around distressed calcium phosphate particles, and dentition repair occurs at a dentition depth of at least 10 microns below the surface.
US10130557B2	Child-resistant blister package A child-resistant blister package. The package has a top face, a bottom face, and a periphery. The package also has a protection layer with a top face, a bottom face and a periphery; a blister layer with one or more cavities; and an access layer with a top face, a bottom face, and a periphery. The bottom face of the access layer has a line of weakness that allows the unit dose to be removed from the cavity in one-step by applying a force to the top of the cavity and pressing the unit dose through the line of weakness. The bottom face of the protection layer and the top face of the access layer are permanently joined along substantially the entire periphery of the package. The blister package can also contain a tear resistant layer.
US10130554B2	System for therapeutic treatment by vacuum pressure and method of use thereof A therapeutic device for applying pressure to a portion of a wearer's body is provided. The device includes a flexible enclosure formed from a flexible material and configured to enclose at least a portion of the wearer's body, thereby forming a cavity between an inner surface of the enclosure and the body. The device also includes at least one port extending through the flexible enclosure for accessing the cavity; and a fluid evacuation pump in fluid communication with the cavity. The device is configured such that, upon actuation of the pump, the flexible enclosure transitions from a relaxed position to a compressed position, in which the flexible enclosure exerts a compression force against the wearer's body. Optionally, the flexible enclosure defines a cross sectional area, wherein the cross sectional area in the relaxed position is greater than the cross sectional area in the compressed position.
US10130547B2	Exoskeleton device with sitting support and method of operation thereof An exoskeleton device includes a plurality of braces that are each attachable to a part of a user. A plurality of joints connects adjacent braces. Each joint is controllable to bend or unbend so as to cause the exoskeleton device to change between an erect configuration and a sitting configuration. At least one support column is extendible from a brace. A length of the support column is adjustable. A controller is configured to adjust the length of the support column in coordination with the bending or unbending of a joint to provide support for the exoskeleton device when in the sitting configuration.
US10130546B2	Multi-active-axis, non-exoskeletal rehabilitation device A robotic device for operation in association with an appendage of a user, wherein the appendage of the user has an endpoint, the robotic device including: a base; and a robotic arm attached to the base and having an endpoint, the robotic arm having at least two active degrees of freedom relative to the base and being configured so that when the base is appropriately positioned relative to a user, the reference frame of the robotic device is oriented generally similarly to the reference frame of the user and motions of the endpoint of the appendage of the user are mimicked by motions of the endpoint of the robotic arm.
US10130541B2	Device for supporting a patient to allow performance of a breast exam A device for supporting a patient to allow an exam to be performed on the patient's breast, including a supporting table which has a longitudinal axis of extension and on which the patient can lie in a reclining position; the supporting table is provided, in proximity to one end of it, with a through hole for receiving the breast to be examined; a mounting frame for mounting the supporting table and equipped with at least one actuator for adjusting the supporting table in height; the supporting table is divided into a first portion and second portion along an axis; the first portion is smaller in extension along the longitudinal axis than the second portion and is provided with the through hole; the two portions are movably connected to each other.
US10130526B2	Portable wound therapy system A portable system for subatmospheric pressure therapy in connection with healing a surgical wound, includes a wound dressing dimensioned for positioning relative to a wound bed of a subject, a portable subatmospheric pressure mechanism dimensioned to be carried or worn by the subject and a container for collecting exudates from the wound bed removed under the subatmospheric pressure supplied by the subatmospheric pressure mechanism. The portable subatmospheric pressure mechanism includes a housing, a subatmospheric pressure source disposed within the housing and in fluid communication with the wound dressing to supply subatmospheric pressure to the wound dressing and a power source mounted to or within the housing for supplying power to actuate the subatmospheric pressure source.
US10130523B2	Self-contained electronic device for detecting and alerting of the saturation of a protection layer article for urofecal incontinence The invention relates to a self-contained electronic device for detecting and alerting of the saturation of a protection layer article used for urofecal incontinence, including at least one self-contained electrical generator module comprising an arrangement of pairs of elements having metal electrodes that are electrically connected to one another and distributed over a predetermined inner area of the article, made of zinc-copper in particular, intended for generating a current upon contact with an acidic and aqueous urofecal medium by means of a redox reaction, in order to electrically control, in a self-contained manner, the inner and outer means for giving notification of the saturation, in particular light means, sound means, or means for analogue or digital transmission of wired or wireless signals. The invention is useful in a protection layer article for urofecal incontinence for seniors or infants.
US10130518B2	Appurtenances including sensors for reporting information regarding wound dressings In some embodiments, an appurtenance to a wound dressing includes: a substrate with at least one surface of a size and shape to mate with a surface of a wound dressing; a plurality of projections attached to the substrate and positioned to secure the substrate to the wound dressing; one or more sensor units attached to the substrate, the one or more sensor units configured to sense a condition of the wound dressing; and a transmission unit attached to the substrate and operably coupled to the one or more sensor units, the transmission unit including circuitry configured to transmit information associated with the one or more sensor units.
US10130514B2	System and method for delivery of a therapeutic agent to the inner ear Embodiments of the invention provide systems and methods for delivering therapeutic compositions to the inner-ear to treat inner-ear disorders. An embodiment of such a system comprises a sheath for insertion into the auditory canal and a cannula which can be inserted through the sheath. The cannula can include a tip for piercing the tympanic membrane and delivering the composition to an inner-ear tissue surface. The system may also include a therapeutic composition comprising a therapeutic agent and a thixotropic material which allows the composition to be delivered (e.g., by injection) through the cannula in liquid form and transition to gel-form once delivered to the tissue surface. A method for using the system comprises introducing the sheath into the ear, introducing the cannula through the sheath to pierce the tympanic membrane and position the tip adjacent an inner-ear tissue surface; and delivering the composition through the cannula to adhere to the tissue surface.
US10130513B2	Active confocal imaging systems and methods for visual prostheses The disclosure features systems for providing information to a user about the user's environment, the system featuring a detection apparatus configured to obtain image information about the environment, where the image information corresponds to information at multiple distances relative to a position of the user within the environment, and an electronic processor configured to obtain focal plane distance information defining a set of one or more distance values relative to the position of the user within the environment, construct one or more confocal images of the environment, from the image information and the set of one or more distance values, wherein each of the one or more confocal images corresponds to a different distance value and comprises a set of pixels, and transform the one or more confocal images to form one or more representative images comprising fewer pixels and a lower dynamic range.
US10130512B2	Headgear for observation of eye movements An apparatus for covering a left eye and a right eye of a human, includes: a first eye piece configured for covering a left eye of a human; and a second eye piece configured for covering a right eye of the human; wherein the first eye piece and the second eye piece are configured for preventing transmission of visible light; and wherein at least one of the first eye piece and the second eye piece comprises a region that is transparent for electromagnetic radiation with a wavelength range outside a visible range.
US10130509B2	Drainage device and method of producing same The invention relates to medical technology and is intended for use in ophthalmology in the surgical treatment of various types of glaucoma. According to a first aspect of the invention, the drainage device for use in the surgical treatment of glaucoma is formed from a bioresorbable material in the form of a hollow profile with a closed contour in cross section, ensuring the possibility of the scleral flap passing through the cavity of the device during the surgical treatment. As a result, the formation of adhesions under the scleral bed, along the scleral flap rib and also between the scleral flap and the conjunctiva is prevented, the ease and reliability of fixing the device on the scleral flap is increased, and adverse immune and inflammatory reactions are reduced. According to a second aspect, the described drainage device is produced by manufacturing a blank from polymer material on a rod in the form of a hollow profile of closed cross section and subsequently cutting at least one section out of the blank in order to produce at least one drainage device. According to a third aspect of the invention, in order to produce the drainage device, a blank in the form of a hollow profile of closed cross section is woven from threads, and at least one section is subsequently cut out of the blank in order to produce at least one drainage device. According to a fourth aspect of the invention, blanks in the form of strips are produced from a flat preliminary blank made of polymer material, wherein the drainage device is produced by connecting the ends of at least one blank.
US10130507B2	Dry eye treatment device A dry eye treatment device and method of use are disclosed for applying heat to the exterior surface of an eyelid to treat dry eye symptoms which can be caused by meibomian gland dysfunction (MGD). More specifically, a user operable main unit and hand piece are provided that allow the user to heat his/her or another patient's eyelids to a desired temperature, which can effectively and efficiently raise the temperature at the meibomian glands sufficient to melt, loosen, or soften occlusions or obstructions in the meibomian glands, thereby restoring natural secretory function to the meibomian glands.
US10130506B2	Closure system for an ostomy pouch and related methods An ostomy closure is disclosed for sealing an ostomy pouch after use and removal from an ostomy mounting plate. The ostomy closure may comprise a flexible storage bag having a bag base and a bag opening and define a bag chamber. The bag base may couple to an exterior surface of the ostomy pouch. The bag opening may retract over the ostomy pouch and define a bag pouch enclosure for encapsulating the ostomy pouch within the bag chamber to prevent leakage of contents within the ostomy pouch from and through flexible storage bag upon being securely sealed at an opened end.
US10130504B1	Inflatable prosthetic boot insole A foot support for a prosthetic boot has a shape-holding layer and cushion layers on opposite sides of the shape-holding layer. Covers made of nylon and vinyl laminates surround the layers. The vinyl laminates are fused by welding edges of the cover around the foot support. The edge welding surrounds the foot support. An inner parallel welding holds a valve and forms an inflation passage. The inner welding continues around concave curved edges of the shape-holding and cushion layers and terminates where it rejoins the outer welding, forming an inflatable tarsal and metatarsal supporting chamber. A small hard pump has two ends to either increase or reduce pressure in the supporting chamber.
US10130502B2	Transpyloric anchoring A gastrointestinal implant device (2800) comprises a planar proximal element (220) configured to reside in a stomach to resist distal migration, a distal element (222) configured to reside in an intestine to resist proximal migration and one or more tethers (224) coupling the planar proximal element to the distal element.
US10130498B2	Stent with flexible hinge An endoprosthesis may include an expandable tubular framework expandable from a compressed state to an expanded state and include a plurality of strut rows, wherein adjacent strut rows define interstices spacing the adjacent strut rows apart, and a plurality of connectors extending across the interstices and interconnecting adjacent strut rows, at least some of the plurality of connectors defining a flexible hinge portion. The lengths of the interstices between adjacent strut rows may vary along the length of the expandable tubular framework. The plurality of connectors extend radially outward beyond an outer diameter of the plurality of strut rows in the expanded state. The plurality of connectors are configured to engage a wall of a body lumen in the expanded state to inhibit migration of the endoprosthesis subsequent implanting the endoprosthesis in the body lumen.
US10130495B2	Prosthetic ankle and foot combination A prosthetic ankle and foot combination has an ankle joint mechanism constructed to allow damped rotational movement of a foot component relative to a shin component. The mechanism provides a continuous hydraulically damped range of ankle motion during walking with dynamically variable damping resistances, and with independent variation of damping resistances in the plantar-flexion and dorsi-flexion directions. An electronic control system coupled to the ankle joint mechanism includes at least one sensor for generating signals indicative of a kinetic or kinematic parameter of locomotion, the mechanism and the control system being arranged such that the damping resistances effective over the range of motion of the ankle are adapted automatically in response to such signals. Single and dual piston hydraulic damping arrangements are disclosed, including arrangements allowing independent heel-height adjustment.
US10130491B2	Spinal implant with attachment system The embodiments of the present disclosure relate to a spinal implant assembly having features to prevent or minimize fixation elements, such as screws, from being dislodged, or from backing out over time and with use. The spinal implant assembly may comprise an implantable body having first apertures for receiving fixation elements. A plate configured to nest against the posterior portion of the implantable body and comprising one or more second apertures can be provided. These second apertures permit access to the head portions of the fixation elements. One or more locking elements are then passed through the second apertures and engage the head portions of the fixation elements. In addition, the plate may comprise an adjustable arm to allow the plate to be used with implantable bodies of different size.
US10130484B2	Subchondral treatment of joint pain of the spine Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.
US10130483B2	Tibial component with enhanced radial cement fixation A cemented tibial prosthesis having a bone-contacting surface with a porous outer rim. With the bone-contacting surface seated against a resected proximal tibia, bone cement or another suitable adhesive will travel into the pores of the porous outer rim to enhance the connection between the tibial prosthesis and the tibia.
US10130481B2	Patellar ligament spacer for ACL injuries A method and implant to treat anterior cruciate ligament (ACL) injuries are disclosed. The method involves advancing the insertion of the patellar ligament to the proximal tibia. The implant includes a spacer (30) which is inserted between the patellar ligament and the tibia and fixed to the tibia. The spacer decreases the angle between the patellar ligament and the tibia plateau and consequently modifies the internal joint force, restoring stability to the joint even if the ACL is ruptured. The method and implants are applicable to both human and canine patients.
US10130479B2	Method and implant for replacing damaged meniscal tissue A method and apparatus for replacing damaged meniscal tissue includes a meniscus implant including a porous body having a plurality of interconnected open micro-pores and one or more open cavities for receiving meniscal tissue. The interconnected micro-pores are arranged to allow fluid to flow into the porous body and are in fluid communication with the one or more open cavities.

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