Diphenyl compound |
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申请号 | JP16743090 | 申请日 | 1990-06-25 | 公开(公告)号 | JPH0356431A | 公开(公告)日 | 1991-03-12 |
申请人 | Fujisawa Pharmaceut Co Ltd; | 发明人 | MATSUO MASAAKI; OGINO TAKASHI; IKARI NORIHIRO; TAKATANI TAKAO; SENOO HACHIRO; SHIMOMURA KYOICHI; | ||||
摘要 | NEW MATERIAL:A compound expressed by formula I [R 1 is halogen, (protected amino, hydrazino, aminophenoxy, (protected) OH, etc.; R 2 is halogen, alkylamino, (protected) amino, (protected) hydrazino, etc.; R 3 is H, alkyl, halogen, CN, carboxy, etc.; R 3a is H or alkyl; R 4 and R 4a are H, alkyl or halogen; A is CH(OH), CH 2 , CO, O, S, SO 2 , C(=NOR a ) (R a is H, alkyl, alkenyl, etc.), SO 2 N(RC) (RC is H or alkyl), etc.] and salts thereof. EXAMPLE: 1,1-Bis(4-aminophenyl)-1-methoxyiminomethane. USE: A remedy for pains, inflammatory diseases, rheumatism, nephritis and thrombocytophenia. PREPARATION: For example, a compound expressed by formula II, its reactive derivative or salt thereof is reacted with a compound expressed by formula III or salt thereof to afford the compound expressed by formula I (A is SO 2 NH). COPYRIGHT: (C)1991,JPO&Japio |
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说明书全文 |