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序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
41 COMPOSITIONS AND COMBINATIONS FOR THE TREATMENT OF ANGIOGENESIS DISEASES AND DISORDERS PCT/IL2016/050213 2016-02-25 WO2016135728A1 2016-09-01 SREDNI, Benjamin

The present invention relates to compositions, combinations and methods for treating, reducing, ameliorating, alleviating, or inhibiting the progression of, angiogenesis diseases and disorders in a patient in need thereof (such as for example AMD), utilizing Te-containing compounds.

42 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound US16840871 2020-04-06 US11512105B2 2022-11-29 Kum Hee Lee; Seungyeon Kwak; Yoonhyun Kwak; Ohyun Kwon; Aram Jeon; Whail Choi; Kyuyoung Hwang; Byoungki Choi; Hyeonho Choi
An organometallic compound represented by Formula 1, an organic light-emitting device including the organometallic compound, and a diagnostic composition including the organometallic compound: M(L1)n1(L2)n2,  Formula 1 wherein, in Formula 1, M, L1, L2, n1, and n2 are each independently the same as described herein.
43 TELLURIUM-CONTAINING COMPOUNDS FOR AFFECTING MALE'S FERTILITY FOLLOWING CHEMOTHERAPY AND/OR RADIOTHERAPY US13143546 2010-01-07 US20110275709A1 2011-11-10 Benjamin Sredni; Michael Albeck; Benjamin Ron
Use of tellurium-containing compounds for maintaining and/or augmenting fertility in a male subject following chemotherapy and/or radiotherapy is disclosed. The tellurium-containing compound is utilized in combination with a chemotherapeutic agent and/or radiation, such that the male subject treated by the chemotherapeutic agent and/or radiation and by the tellurium-containing compound is instructed to refrain from conceptive sex for a pre-determined time period, following the chemotherapy and/or radiotherapy, during which conception is undesired.
44 Glutathione peroxidase mimetics and uses thereof US11543994 2006-10-06 US07923442B2 2011-04-12 Dusan Kuzma; Thomas G. Back; Noah Berkowitz
This invention relates to novel organoselenium and tellurium compounds, processes of producing the same and methods of use thereof. The compounds function as mimetics for the catalyst selenoenzyme glutathione peroxidase, which protects cells from oxidative stress.
45 Method and composition for reducing tumor development with a combination of platinum and tellurium or selenium compounds US357127 1994-12-15 US5654328A 1997-08-05 Benjamin Sredni; Michael Albeck
There are provided compositions for, and a method of, treating malignancies which comprise effective amounts of a novel combined therapy comprising a platinum compound and a tellurium or selenium compound, e.g., ammonium trichloro (dioxoethylene-O,O-tellurate), and administering the respective compounds simultaneously or separately.
46 Complexes of tellurium and selenium derivatives US123422 1993-09-17 US5475030A 1995-12-12 Benjamin Sredni; Leo Pavliv; Michael Albeck
A novel complex of a class of tellurium and selenium compounds is disclosed, which is based on a complexing agent and the particular compound to be complexed.
47 Compounds for the induction of in vivo and in vitro production of cytokines US136396 1987-12-22 US5093135A 1992-03-03 Michael Albeck; Benjamin Sredni
Certain tellurium compounds have been found to have the ability to stimulate the in vivo and in vitro production of cytokines and thier receptors. These compounds may be utilized in the treatment of autoimmune diseases, immune diseases and infectious diseases.
48 Complexes of tellurium and selenium derivatives US172643 1988-03-24 US4929739A 1990-05-29 Benjamin Sredni; Leo Pavliv; Michael Albeck
A novel complex of a class of tellurium and selenium compounds is disclosed, which is based on a complexing agent and the particular compound to be complexed.
49 Fluorocarbon metalloid compounds of tetrafluoroethylene and sulfur, selenium or phosphorus and their preparation US67845157 1957-08-15 US2931803A 1960-04-05 KRESPAN CARL G
50 Polyphenolic selenium compound having functional group of alkali metal ion and selenium complex US14158819 2014-01-18 US20140323745A1 2014-10-30 Gong Chen; Kunyuan Song
A polyphenolic selenium compound having a functional group of alkali metal ion and selenium complex which has an aromatic ring is provided, wherein the aromatic ring comprises at least two functional groups, each of which is one member selected from the group consisting of oxygen functional group, sulphur functional group, phosphorus functional group and nitrogen functional group; and selenium complex functional group is formed by selenium, alkali metal ion and the functional group. The polyphenolic selenium compound having a functional group of alkali metal ion and selenium complex of the present invention has characteristics of over 20% selenium content and no toxicity. Because it has revolutionary effects in killing bacteria, virus and cancer cell, enhancing human immunity, removing oxygen free radicals and etc., it holds a vital medicinal value.
51 Method for the stimulation of bone marrow cells US278957 1988-12-02 US4946437A 1990-08-07 Benjamin Sredni; Michael Albeck
A novel method is disclosed for the stimulation of the differentiation of bone marrow cell which is based on the administration of an effective amount of a tellurium compound which has a stimulating effect on bone marrow cells.
52 Photographic element containing a macrocyclic ether compound US77131 1987-07-23 US4782013A 1988-11-01 Arthur H. Herz; Roger L. Klaus
This invention is directed to a photographic element containing a radiation-sensitive silver halide emulsion layer and a macrocyclic thia or selena ether compound which also comprises oxygen atoms. These macrocyclic compounds are improved silver halide ripening agents.
53 Tellurium and selenium compounds for the induction of in vivo and in vitro production of cytokines US57800 1987-06-03 US4764461A 1988-08-16 Michael Albeck; Benjamin Sredni
Certain tellurium compounds have been found to have the ability to stimulate the in vivo and in vitro production of cytokines and their receptors. These compounds may be utilized in the treatment of certain tumors, autoimmune diseases, immune diseases and infectious diseases.
54 Organic derivatives of tellurium and selenium and their use to stimulate cytokine production US782129 1985-09-30 US4761490A 1988-08-02 Michael Albeck; Benjamin Sredni
Certain tellurium compounds have been found to have the ability to stimulate the in vivo and in vitro production of cytokines and their receptors. These compounds may be utilized in the treatment of certain tumors, autoimmune diseases, immune diseases and infectious diseases.
55 Pharmaceutical compositions of tellerium and selenium compounds for the induction of in vivo and in vitro production of cytokines US57799 1987-06-03 US4752614A 1988-06-21 Michael Albeck; Benjamin Sredni
Certain tellurium compounds have been found to have the ability to stimulate the in vivo and in vitro production of cytokines and their receptors. These compounds may be utilized in the treatment of certain tumors, autoimmune diseases, immune diseases and infectious diseases.
56 Tellurium (IV) compounds and compositions US181324 1980-08-25 US4355097A 1982-10-19 Henry J. Gysling; Sylvia A. Gardner
Disclosed are tellurium (IV) compounds represented by the formula: ##STR1## wherein: D is a Lewis base function containing a group VA or VIA donor atom;Q represents the atoms necessary to complete a 5- or 6-membered ring, when taken together with C, D and Te, when m is 1 and represents the atoms linking C and D when m is greater than 1;R.sub.1 and R.sub.2 are independently selected from the group consisting of hydrogen, alkyl and aryl;X is an anion;n is 1 or 2; andm is an integer from 1 to 500.These compounds are useful in an image-forming combination comprising the described Te(IV) compound and a reducing agent. The image-forming combination is useful in a variety of materials, including a dry amplification element.
57 Highly chlorinated aryl sulfides and process for the manufacture thereof US12507761 1961-07-19 US3217044A 1965-11-09 HELMUT KLUG
58 Compounds for the induction of in vivo and vitro production of cytokines EP88116788.6 1988-10-10 EP0311138A3 1990-07-18 Albeck, Michael; Sredni, Benjamin

The invention refers to a compound of the formula: wherein Q is Te or Se; t is 1 or 0; us is 1 or 0; v is 1 or 0; R, R₁, R₂, R₃, R₄, R₅, R₆, R₇, R₈, and R₉ are the same or different and are independently selected from the group consisting of hydrogen, hydroxyalkyl of 1 to 5 carbons, hydroxy, alkyl of from 1 to 5 carbon atoms, halogen, haloalkyl of 1 to 5 carbon atoms, carboxy, alkylcarbonylalkyl of 2 to 10 carbons, alkanoyloxy of 1 to 5 carbon atoms, carboxyalkyl of 1 to 5 carbon atoms, acyl, amido, cyano, amidoalkyl of 1 to 5 carbons, N-­monoalkylamidoalkyl of 2 to 10 carbons, N,N-dialkylamido­alkyl of 4 to 10 carbons, cyanoalkyl of 1 to 5 carbons, alkoxy of 1 to 5 carbon atoms, alkoxyalkyl of 2 to 10 carbon atoms and -COR₁₀ wherein R₁₀ is alkyl of from 1 to 5 carbons; and X is halogen; while the potassium salt is illustrated, it is understood that other pharmaceutically acceptable salts are within the scope of the invention in a method of stimulating the production of lymphokine by administering to a host an effective amount of such a compound and thus, also treating acquired immune deficiency syndromes, pharmaceutical compositions containing such compounds and a process of preparing the compounds by contacting an alykene glycol with tellurium tetrachloride in the presence of a potassium or ammonium halide at elevated temperatures.

59 Compounds for the induction of in vivo and in vitro production of cytokines EP85402070.8 1985-10-25 EP0194393B1 1990-06-13 Albeck, Michael; Sredni, Benjamin
60 Radiation sensitive element containing a macroheterocycle EP88420171.6 1988-05-30 EP0295190A1 1988-12-14 Friour, Gérard; Paris, Christian; Riveccie, Marcel; Herz, Arthur

This invention is directed to a radiation sensitive silver halide emulsion comprising a macroheterocycle having an acid function and to an element containing such emulsion. The macroheterocycle comprises at least two atoms of sulfur or selenium, each of which atoms being separated from one another by a chain of at least two carbon atoms. Such compound acts as a solvent and as a growth modifying agent for silver halide grains. Also described is a process for modifying the growth of silver halide grains.

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