序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
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161 | MANUFACTURE OF DIMETHYL ETHER OR OLEFINS FROM METHANE, USING DI(METHYL-SULFONYL) PEROXIDE AS RADICAL INITIATOR | PCT/US2007/000288 | 2007-01-08 | WO2007136425A3 | 2007-11-29 | |
Enhancements and options are disclosed for converting methane into other compounds, via methane-sulfonic acid (MSA). One enhancement involves using di(methyl- sulfonyl) peroxide (DMSP, formed by electrolysis of MSA) as the initiator to start a chain reaction that bonds methane to SO3. Also disclosed are improvements in: (i) using catalysts to convert MSA into olefins, or into methyl-methane-sulfonate, an ester intermediate; (ii) converting MSA into dimethyl ether, a fuel that can be stored and transported under low pressures as a liquid; and, (iii) injecting DME directly into natural gas pipelines as "makeup" gas, to supplement natural gas supplies. |
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162 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | PCT/US2006006698 | 2006-02-24 | WO2006091870A3 | 2007-01-18 | REDDY M V RAMANA; REDDY E PREMKUMAR; BELL STANLEY C |
a,ß-Unsaturated sulfides, sulfones, sulfoxides and sulfonamides according to Formula (I): wherein Ar1, Ar2, X, n, * and R are as defined herein, are prepared by dehydration of ß-hydroxy sulfides, sulfones, sulfoxides or sulfonamides. | ||||||
163 | COMPOUNDS FOR TREATING NEUROLOGIC DISEASES, OTOLOGIC DISEASES, OR OPHTHALMOLOGIC DISEASES AND METHODS OF USE THEREOF | PCT/US2005016132 | 2005-05-06 | WO2005108353A3 | 2006-10-26 | STRACHER ALFRED; KESNER LEO |
Described herein are compounds and methods for treating or preventing a neurologic, otologic, or ophthalmologic disease in a subject. | ||||||
164 | METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF | PCT/IL2004000535 | 2004-06-17 | WO2004110339A3 | 2006-07-27 | ZIV ILAN; SHIRVAN ANAT |
The invention provides novel methods for selective targeting of chemical compounds to cells undergoing a death process, in particular apoptosis, and to platelets undergoing activation during blood coagulation. The invention further provides compounds to be used in said methods for medical practice, for diagnostic and therapeutic purposes. | ||||||
165 | PROCESS AND INTERMEDIATES TO PREPARE THE SULPHONYL DERIVATIVES OF CHOLECALCIFEROL | PCT/PL2005/000030 | 2005-05-13 | WO2005110979A2 | 2005-11-24 | CHODYNSKI, Michal; KRUPA, Malgorzata; FITAK, Hanna; WINIARSKI, Jerzy; RYZNAR, Teresa; GORECKI, Bartlomiej; SZELEJEWSKI, Wieslaw; KUTNER, Andrzej |
Preparation of sulphonyl derivatives of cholecalciferol of Formula (I), wherein R1 is protective group, preferably t-butyl(dimethyl)silyl, where R2 is heterocyclic group, such as 2-thiazolyl, 2-benzothiazolyl, 1-phenyl-lH-tetrazo-5-yl, 2-pyridyl, 2-pyrimidynyl, 1-isochinolinyl, 1-methyl-2-imidazyl, 4-alkyl-1,2,4-triazo-3-yl, comprising the conversion of the hydroxyl derivative of cholecalciferol into the corresponding sulfide followed by its oxidation to the respective sulphone characterized by the use of hydroxyl derivative of cholecalciferol as a starting material, which triene system is protected as Diels-Alder adduct, and in particular as an adduct with sulfur dioxide of the formula 2a. Novel are derivatives of formula 3a and 4, isolated in the process provided in the invention. |
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166 | PROCESS FOR PRODUCTION OF ACETYL ANHYDRIDES AND OPTIONALLY ACETIC ACID FROM METHANE AND CARBON DIOXIDE | PCT/US2004023681 | 2004-07-23 | WO2005009927A3 | 2005-03-24 | BELL ALEXIS T; MUKHOPADHYAY SUDIP; ZERELLA MARK; SUNLEY JOHN GLENN; GAEMERS SANDER; MUSKETT MICHAEL JAMES |
Acetyl anhydrides such as acetyl sulfate are produced by a process for comprising contacting methane and carbon dioxide in an anhydrous environment in the presence of effective amounts of a transition metal catalyst and a reaction promoter, and an acid anhydride compound, and optionally an acid. The acetyl anhydride can be contacted with water to produce acetic acid or with an alcohol to produce a product comprising an acetate ester and that may also comprise acetic acid. Optionally, water in stoichiometric amounts or less, with respect to the acetic anhydride, may be fed to a continuous process of this type to produce some acetic acid in situ. | ||||||
167 | ANIONIC PHTHALIC ACID ESTER COMPOUNDS AND STAIN RESISTANT COMPOSITIONS | PCT/US2003/030715 | 2003-09-30 | WO2004031135A2 | 2004-04-15 | WILLIAMS, Michael, S.; SARGENT, Thomas, N. |
This invention relates to compounds of formula (I) wherein A is an unsaturated alkylene moiety; B the residue of a polyol wherein one hydroxyl moiety is esterified with one carboxyl moiety of the phthalic acid moiety; D is the residue of a polyol wherein one hydroxyl moiety is esterified with another carboxyl moiety of the phthalic acid moiety, and another hydroxyl moiety is esterified with one carboxyl moiety of the unsaturated alkylene moiety; E is the residue of polyol wherein one hydroxyl moiety is esterified with another carboxyl moiety of the unsaturated alkylene moiety; and M is a cation. The compounds can be used alone, or polymerized, or polymerized and combined with other polymers, to form effective stain and soil repellent compositions. |
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168 | ANTIMICROBIAL BIARYL COMPOUNDS | PCT/US0124067 | 2001-08-01 | WO0209648A3 | 2002-06-27 | JEFFERSON ELIZABETH ANN; SWAYZE ERIC |
Provided are antibacterial compounds having Formula (I) wherein X is CH, O, S, N or NH; Y is CH or N; n is 0 or 1; one of R1 and R1' is -C(O)NR5R5', -C(O)-Q-NR5R5', -CH2NR5R5' or -S(O)2NR5R5' and the other is H or R3, one of R2 and R2' is -NHC(O)R6 or -NHS(O)2R6 or -NHS(O)R6 and the other is H or R4; Q is an amino acid or peptide; R3 is H, halogen, -NR5R5' or -NHC(O)R6; R4 is selected from the group consisting of H, halogen, hydroxyl, amino, carboxyl, alkyl, alkenyl and alkynyl; R5 is selected from the group consisting of H, alkyl, alkenyl or alkynyl optionally substituted with halogen, OH, amino, amidinyl, guanidinyl, urea, alkyl, carboxyl, oxo, carboxamide; R5' is H or R5 and R5' together form a 5-16 member heterocycle optionally substituted with halogen, OH, amino, alkyl, carboxyl, carbonyl or carboxamide; and R6 is selected from the group consisting of H; amino, alkyl, alkenyl or alkynyl, each optionally substituted with halogen, amino, amidinyl, guanidinyl, urea, carboxyl or carbvoxamide; a 5-16 member carbocycle or heterocycle; and a 5-16 member heterocycle-substituted alkyl or carbocycle-substituted alkyl, wherein said carbocycle and heterocycle are optionally substituted with halogen, OH, amino, alkyl, carboxyl, oxo or carboxamide. | ||||||
169 | METHOD FOR THE PURIFICATION OF ARYL SULFONIC ACIDS AND SALTS | PCT/US2001/000417 | 2001-01-05 | WO01051459A1 | 2001-07-19 | |
Solid aryl sulfonates are purified by preferentially dissolving impurities into an aqueous liquid phase. | ||||||
170 | TW107147196 | 2018-12-26 | TW201930328A | 2019-08-01 | WOJTCZAK WILLIAM A; MIZUTANI ATSUSHI; PARK KEE-YOUNG | |
This disclosure relates to methods and compositions for treating a wafer having a pattern disposed on a surface of the wafer. | ||||||
171 | 鹽及含有該鹽之光阻組成物 | TW099139163 | 2010-11-15 | TWI476172B | 2015-03-11 | 市川幸司; ICHIKAWA, KOJI; 落合光良; OCHIAI, MITSUYOSHI; 杉原昌子; SUGIHARA, MASAKO |
172 | COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES | EP19174479.6 | 2014-03-14 | EP3607821B1 | 2022-08-03 | PETERS, Kevin; SHALWITZ, Robert; JANUSZ, John; SMITH, Alexander |
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed. | ||||||
173 | PROCESS FOR PURIFYING ALKANESULFONIC ANHYDRIDE AND PROCESS FOR PRODUCING ALKANESULFONIC ACID USING THE PURIFIED ALKANESULFONIC ANHYDRIDE | EP18717080.8 | 2018-04-18 | EP3612515B1 | 2022-07-20 | WORTMANN, Juergen; SPIELMANN, Jan; FEDERSEL, Katharina; RUETHER, Feelly |
A process for purifying alkanesulfonic anhydride that includes feeding a stream containing alkanesulfonic anhydride, sulfuric acid, high boilers and residual low boilers into a melt crystallization to form crystals of the alkanesulfonic anhydride suspended in mother liquor, and solid-liquid separation to remove the crystals from the mother liquor. | ||||||
174 | VERFAHREN ZUR HANDHABUNG VON WÄSSRIGEN METHANSULFONSÄURELÖSUNGEN MITTELS ROSTFREIER STAHL | EP10768963.0 | 2010-10-26 | EP2496726B1 | 2021-09-08 | FASSBENDER, Stefan; PETERSEN, Peter; LAUTERBACH, Arnulf; RENZ, Günter; BORGMEIER, Frieder; KOLB, Peter |
175 | PROCEDE DE PREPARATION DE DERIVES OXYSULFURES ET FLUORES EN MILIEU LIQUIDE IONIQUE | EP15805177.1 | 2015-12-07 | EP3230263B1 | 2018-09-19 | METZ, François |
176 | SULFONIC ACID GROUP-CONTAINING POLYMER, SULFONIC ACID GROUP-CONTAINING AROMATIC COMPOUND AND METHOD OF MAKING THE SAME, AS WELL AS POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE MOLDED PRODUCT AND SOLID POLYMER FUEL CELL USING THE SAME | EP12833332.5 | 2012-09-06 | EP2758448B1 | 2017-08-02 | CHEN, Qiao; SHAO, Fangke; WU, Gang; IZUHARA, Daisuke; UMEDA, Hiroaki |
177 | SURFACTANT COMPOSITIONS | EP12730808.8 | 2012-06-27 | EP2726589A1 | 2014-05-07 | JAKOBS-SAUTER, Britta; SCHROEDER, Clemens; BREITZKE, Burkhard; SCHOENKAES, Udo; GIUFFRIDA, Giuseppe; MATHESON, Lee; KINSLEY, Kermit; COX, Michael; RUSSEL, Geoffrey Lynn; WINDER, John Barry |
A surfactant composition comprising alkylarylsulfonate molecules wherein more than 30 wt.% of the alkylarylsulfonate molecules of the surfactant composition are one or more species of the formula: [R - X - Ar (SO 3) -] a [M n+] b wherein: X is a linear acyclic aliphatic hydrocarbyl chain; R is bound to a non-terminal carbon atom of X and is selected from H and C1, C2, and C3 alkyl groups; X and R together have 9 or 10 carbon atoms; Ar is an aromatic group; M is a cation, n is selected from 1,2 and 3; and a and b are selected such that the alkylarylsulfonate molecule is electroneutral, wherein more than 20 wt.% of the alkylaryl molecules of the surfactant composition have an R which is methyl or ethyl. | ||||||
178 | VERBINDUNGEN MIT (METH)ACRYLAT-RESTEN UND SULFONAT- ODER SULFATGRUPPEN, POLYMERE UND KONDENSATE DARAUS SOWIE VERWENDUNG DER POLYMERE UND KONDENSATE | EP12723194.2 | 2012-05-24 | EP2714653A1 | 2014-04-09 | WOLTER, Herbert; SEYFRIED, Mona; NIQUE, Somchith |
The invention relates to a compound, comprising at least three functionalities, that is (a) a sulfonate or sulfate group of the formula - (O) d-SO 3M with d = 0 or 1 and M = hydrogen or a monovalent metal cation or the corresponding fraction of a polyvalent metal cation, (b) a (meth)acryl group, and (c) either (c1) at least one further (meth)acryl group or an inorganically condensable group, and/or (c2) a further carboxylic acid function, and/or (c3) a function which increases the refractive index of a material produced from the compounds, that is a thioether group, with the proviso that a sulfonate or sulfate group and a (meth)acrylate group are separated from one another in a silicon-free compound via a hydrocarbon-containing group, the carbon chain of which is either interrupted by O, S or NH or contains a linking group. | ||||||
179 | 3-METHANESULFONYLPROPIONITRILE FOR TREATING INFLAMMATION AND PAIN | EP11849401.2 | 2011-12-13 | EP2651407A2 | 2013-10-23 | ST. LAURENT, Joseph, P. |
The present invention relates to purified 3-methanesulfonylpropionitrile or a pharmaceutically acceptable salt thereof, and a method for preparing such compound. The compound has at least 90% (w/w) purity. The present invention is also directed to a pharmaceutical composition comprises the purified compound and a pharmaceutically acceptable carrier. The present invention is further directed to a method for treating inflammation, inflammatory-related disorders, or pain, by administering 3-methanesulfonylpropionitrile or a pharmaceutically acceptable salt or solvate thereof to a subject in need thereof. | ||||||
180 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | EP06736103.0 | 2006-02-24 | EP1896401B1 | 2013-04-10 | REDDY, M.V. Ramana; REDDY,E. Premkumar; BELL, Stanley, C. |