序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
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161 | POLYNUCLEOTIDE VACCINE ADJUVANTS AND FORMULATIONS CONTAINING CATIONIC SURFACTANTS, AND METHODS OF USE | PCT/US0120200 | 2001-06-22 | WO0200844A3 | 2003-06-12 | EVANS ROBERT K |
Improved polynucleotide vaccine adjuvants and related polynucleotide vaccine formulations are disclosed which are useful in prophylactic or therapeutic vaccine and/or gene therapy-based applications. These adjuvants comprise a block copolymer and a cationic surfactant component. The inclusion of a cationic surfactant results in an increased percentage of polynucleotide that is physically associated with the adjuvant in vitro, resulting in enhanced in vivo immune responses to polynucleotide vaccines. | ||||||
162 | ESTERS OF AROMATIC ALKOXYLATED ALCOHOLS AND FATTY CARBOXYLIC ACIDS | PCT/US2002/033198 | 2002-10-17 | WO2003032919A3 | 2003-04-24 | PEREIRA, Abel; WESTERGOM, Christopher; OBUKOWHO, Patrick |
Esters of alkoxylated aromatic alcohol and fatty carboxylic acid are provided. The esters are especially suitable as additives for personal care and cosmetic products. Certain of the esters of alkoxylated aromatic alcohol and fatty carboxylic acid having certain skin spread factor or viscosity are also provided. A personal care or cosmetic product composition that includes from about 0.1% to about 99% of at least one ester of alkoxylated aromatic alcohol and fatty carboxylic acid, and from about 0.1% to 60% of at least one functional ingredient is provided. The functional ingredients in the composition 15 may include active ingredients and additional ingredients. Especially suitable active ingredients are sunscreen active ingredients and antiperspirant active ingredients. Preferred compositions are sunscreen product formulations and antiperspirant products. In one preferred embodiment, the composition further includes at least one cyclomethicone compound present in the amount of from about 1% to 99% by weight of the composition. A method of improving the protection of human or animal skin or hair from radiation and a method of improving the protection of human or animal skin or hair from perspiration are also provided. |
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163 | A SOLVENT EXCHANGE PROCESS | PCT/US2001/017191 | 2001-05-25 | WO01094288A3 | 2002-07-04 | |
A process for recovering an organic acid or a metal salt thereof includes contacting an alcoholic phase containing one or more organic acid(s) or metal salt(s) thereof with water under conditions effective to provide an aqueous phase containing a portion of the organic acid(s) or metal salt (s) thereof. The aqueous phase does not contain substantial amounts of the alcohol(s). This process can also include recovery of the organic acid(s) or metal salt(s) thereof from the aqueous phase. | ||||||
164 | INHIBITORS OF THE ANANDAMIDE TRANSPORTER AS ANALGESIC AGENTS | PCT/US1999/012900 | 1999-06-09 | WO99064389A1 | 1999-12-16 | |
This invention relates to anandamide transport inhibitors and their use as analgesic. | ||||||
165 | SMALL MOLECULE ANTICANCER COMPOUNDS AND RELATED PRODUCTION PROCESS | PCT/US1999/006525 | 1999-04-14 | WO99053086A1 | 1999-10-21 | |
A group of specific branched-chain fatty acids, with significant anticancer effects on human and animals; methods of making using either chemical synthesis or biosynthesis methods; and methods of treating cancer. | ||||||
166 | RADIATION-POLYMERIZABLE COMPOSITION AND PRINTING INKS CONTAINING SAME | PCT/US1998/006155 | 1998-03-31 | WO98044007A1 | 1998-10-08 | |
A radiation-polymerizable composition contains at least one radiation curable acrylate resin oligomer prepared by reacting an alkoxylated polyol with a first acid component which includes an ethylenically unsaturated carboxylic acid; and a rheology modifier prepared by reacting a diepoxide with a second acid component which includes an ethylenically unsaturated carboxylic acid or reactive derivative thereof in the presence of a polyamide based on a polymerized fatty acid. The ethylenically unsaturated carboxylic acids of the first and second acid components are preferably acrylic acid or methacrylic acids. The diepoxide is preferably a diglycidyl ether such as bisphenol A. Colorants such as pigments or dyes optionally may be incorporated into the composition to form a printing ink which is curable by ultraviolet (UV) or electron beam radiation. | ||||||
167 | NEW FATTY ACID DERIVATIVES | PCT/NO1998/000021 | 1998-01-23 | WO98032718A1 | 1998-07-30 | |
The properties of biologically active compounds, for example drugs and agrochemicals, which contain in their molecular structure one or more functional groups selected from alcohol, ether, phenyl, amino, amido, thiol, carboxylic acid and carboxylic acid ester groups are modified by replacing one or more of these functional groups by a lipophilic group selected from those of the formula: RCOO-, RCONH-, RCOS-, RCH2O-, RCH2NH-, -COOCH2R, -CONHCH2R and -SCH2R, wherein R is a lipophilic moiety selected from cis-8-heptadecenyl, trans-8-heptadecenyl, cis-10-nonadecenyl and trans-10-nonadecenyl. | ||||||
168 | 一种基于氧气氧化的羧酸及ε-己内酯联产的新方法 | PCT/CN2020/103204 | 2020-07-21 | WO2021047292A1 | 2021-03-18 | 麻生明; 刘金仙 |
本发明公开了一种基于氧气氧化的高效羧酸及ε-己内酯联产的新方法,即在催化剂催化下,在将醛氧化成相应羧酸的同时将环己酮氧化为ε-己内酯,实现羧酸和ε-己内酯的联产。本方法操作简单,原料和试剂价廉易得,反应条件温和,清洁环保,能够实现羧酸和高附加值的ε-己内酯产品的联产。 |
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169 | PROCESS FOR THE PRODUCTION OF DIACYL PEROXIDES | PCT/EP2020/066229 | 2020-06-11 | WO2020249690A1 | 2020-12-17 | TAMMER, Martinus, Catharinus; TALMA, Auke, Gerardus |
Process for the production of a diacyl peroxide involving the reaction of an anhydride with a peroxyacid, removal of the formed carboxylic acid, production of an anhydride from said carboxylic acid, and recycling of the anhydride within the process. |
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170 | ENERGY-EFFICIENT AND ENVIRONMENTALLY FRIENDLY PROCESS FOR THE PRODUCTION OF TARGET CHEMICAL COMPOUNDS FROM CELLULOSIC MATERIAL | PCT/EP2015/067573 | 2015-07-30 | WO2016020269A1 | 2016-02-11 | MARCKMANN, Henning; HORTSCH, Ralf; SCHUTH, Marco; ARZT, Bernhard |
The present invention is directed to an energy-efficient and environmentally friendly process for the production of chemical target compounds from cellulosic material. In a further aspect, the present invention is directed to a system for conducting the process according to the inventive process. |
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171 | FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF | PCT/US2011/049788 | 2011-08-30 | WO2012030860A1 | 2012-03-08 | ZANGHELLINI, Alexandre Luc |
The invention provides processes for the conversion of pyruvate obtained from sugars or other carbon sources, to valuable C5 materials such as levulinic acid, levulinate esters, valerolactone, and derivatives thereof. |
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172 | METHOD FOR HYDROGENATING 1,2-UNSATURATED CARBONYLIC COMPOUNDS | PCT/EP2010/070371 | 2010-12-21 | WO2011076787A1 | 2011-06-30 | HULTEBERG, Christian; BRANDIN, Jan |
Disclosed is a method of hydrogenating an1,2-unsaturated carbonylic compound to obtain the corresponding saturated carbonylic compound in the presence of a palladium catalyst with heterogeneous distribution of palladium. |
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173 | EPOTHILONE ANALOGUES, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR USE AND THEIR PREPARATIONS | PCT/CN2009000218 | 2009-03-02 | WO2009105969A8 | 2010-10-07 | TANG LI; QIU RONGGUO |
The invention discloses novel epothilone analogues, their pharmaceutical compositions, their use and their preparations, especially discloses the compounds of the formula (I), their preparations and their use for preparing therapeutical compositions used as cell inhibitors. | ||||||
174 | METHOD FOR PRODUCING CARBOXYLIC ACIDS BY OXIDATIVE CLEAVAGE OF UNSATURATED COMPOUNDS | PCT/IB2009/000484 | 2009-03-02 | WO2009109857A1 | 2009-09-11 | MAHESWARI, Palanisamy Uma; DE HOOG, Paul; ENAMORADO, Patrick, Gomez; HAGE, Ronald; REEDIJK, Jan |
The invention provides a method of oxidative cleavage of an unsaturated carbon-carbon bond, said method comprising contacting a reactant molecule containing a carbon-carbon unsaturated bond with a catalytic system comprising (i) either a mixture of tungstate salt and tungstic acid or a mixture of a molybdate salt and molybdic acid; (ii) an aqueous solution of dihydrogen peroxide; (iii) a phase-transfer catalyst; and (iv) a carboxylic acid. |
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175 | 15环噻酮化合物及其制备方法与应用 | PCT/CN2009/000218 | 2009-03-02 | WO2009105969A1 | 2009-09-03 | 邱荣国 |
176 | FATTY ACID BLENDS AND USES THEREFOR | PCT/US2007015017 | 2007-06-27 | WO2008002643A3 | 2008-11-27 | KNUTH MARK E; BEETHAM PETER R; WALKER KEITH A; GOCAL GREGORY FRANCIS WILLIAM |
Provided herein are blends oils or fatty acids comprising more than 50% medium chain fatty acids, or the fatty acid alkyl esters thereof, and having low melting points. Such blends are useful as a fuel or as a starting material for the production of, for example, a biodiesel. Also provided genetically altered or modified plants, modified such that the amount of medium chain fatty acids generated by the plant are increased. Further provided is a method of predicting the melting point of a blend of fatty acid methyl esters and the use of such a method for identifying blends suitable for use as, for example, a biodiesel. | ||||||
177 | NOVEL BIOACTIVE LIPID DERIVATIVES, IMMUNE-DERIVED MOIETIES REACTIVE THERETO, AND METHODS OF MAKING AND USING THE SAME | PCT/US2007/070013 | 2007-05-31 | WO2007140431A3 | 2007-12-06 | SABBADINI, Roger, A.; GARLAND, William, A.; HANSEN, Genevieve |
Compositions and methods for producing monoclonal antibodies and their derivatives reactive against bioactive lipid targets are described. These compositions include derivatized lipids, each of which comprises a bioactive lipid that having a polar head group and at least one hydrocarbon chain (e.g., a lysolipid such as lysophosphatidic acid) in which a carbon atom has been derivatized with a pendant reactive group; immunogens made by linking a derivatized lipid to a carrier moiety (e.g., a earner protein, polyethylene glycol); monoclonal antibodies and derivatives produced by immunizing an animal with such an immunogen; and therapeutic and diagnostic compositions containing such antibodies and antibody derivatives. Methods for making such derivatized lipids, immunogens, and monoclonal antibodies and derivatives, and detecting or using such antibodies once generated, are also described. |
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178 | NEW SUNSCREEN COMPOUNDS AND COMPOSITIONS CONTAINING SAME AND METHODS FOR USE THEREOF | PCT/US2004042962 | 2004-12-20 | WO2005062860A3 | 2006-05-04 | GONZALEZ ANTHONY D; PECHKO ANDREW H; ANDERSON GLEN T; KALAFSKY ROBERT E |
There is provided a photostable and synergistically enhanced topical sunscreen composition that provides increased substantivity, waterproofness, sweat resistance and rub off resistance. There is further provided methods of enhancing the photostability of a sunscreen active in a topical sunscreen composition, synergistically enhancing the W absorbance of a topical sunscreen composition having a sunscreen active, and enhancing the substantivity, waterproofness, sweat resistance and rub off resistance in a topical sunscreen composition. The preferred compositions and methods have a sunscreen active, a cosmetically acceptable vehicle, and novel 2 substituted-3,3-diaryl-2-propenoic acid derivatives with [A] a C16 to C50 straight or branched chain, substituted or un-substituted, conjugated or non conjugated hydrocarbon, or [B] a siloxane, polysiloxane, organo-modified polysiloxane residue, a group represented by the formula R10 [Si (R10) 2] n- and R11 which is a silicone residue derived from a silicone represented by the formula R110H having a molecular weight up to about 30,000, wherein each R10 is independently selected from the group consisting of alkyl, alkoxy, aryl and aryloxy and n is from (1) to about (500). | ||||||
179 | STRUCTURED TRIGLYCERIDES AND EMULSIONS COMPRISING SAME | PCT/IL2005000257 | 2005-03-03 | WO2005084129A8 | 2005-12-01 | ROZEN GEILA; SHOCHAT IRIT |
The present invention relates to structured triglyceride, to parental nutrition emulsions comprising same, and use thereof. In particular, the invention relates to structured triglycerides comprising at least one medium chain C6-C12 fatty acid and at least one fatty acid selected from the group consisting of long chain C14-C18 or very long chain C20-C22 fatty acids, preferably each fatty acid is present in a predetermined position of the glycerol backbone. The parenteral nutrition emulsions are particularly useful for nourishing preterm-and term-infants, children, critically ill patients, and cancer patients. | ||||||
180 | MELDONIUM SALTS, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS | PCT/LV2004000005 | 2004-07-15 | WO2005012233A8 | 2005-05-19 | KALVINSH IVARS; BIRMANS ANATOLIJS |
New salts of Meldonium, the method of their preparation, and pharmaceutical formulation on their basis have been described. The general formula of these salts is X-(CH3)3N+NHCH2CH2COOH where X- is an acid anion selected from the group of pharmaceutically acceptable acids. Practically non-hygroscopicand/or increased thermal stability and/or lasting action Meldonium hydrogen salts of fumaric acid, phosphoric acid, oxalic acid, maleic acid, and pamoic acid as well as Meldoinum orotate and galactarate are especially suitable. Novel pharmaceutical formulations containing non-hygroscopicand/or increased thermal stability and/or lasting action 3-(2,2,2-trimethylhydrazinium) propionate salts for oral, parenteral, rectal and transdermal introduction are concurrently described. |